David Sinclair Reveals Why He Takes NMN with TMG

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  • Опубліковано 28 жов 2024

КОМЕНТАРІ • 59

  • @WellnessMessiah
    @WellnessMessiah  Рік тому +3

    Since 2007, I've been researching and testing the best longevity supplements.
    What did I find?
    You can get my full supplement routine for FREE when you get this app: wellnessmessiah.com/app

  • @awhippetslife
    @awhippetslife 11 місяців тому +23

    I’ve been taking TMG for three weeks now and I am seeing my BP go from High 140/100 down to 120/75-80.

    • @TheCloeboy
      @TheCloeboy 10 місяців тому

      Congrats. How many mg/day do you take?

    • @sajrambob6794
      @sajrambob6794 10 місяців тому

      How much per day?

    • @GregAlexanderOfficial
      @GregAlexanderOfficial 10 місяців тому +4

      My blood pressure has done the exact same thing

    • @sajrambob6794
      @sajrambob6794 10 місяців тому

      @@GregAlexanderOfficial how much tmg per day?

    • @moiLawUk
      @moiLawUk 9 місяців тому

      There's been research saying it increases cholesterol however ?

  • @DoNotAgePartners
    @DoNotAgePartners Рік тому +17

    So important to take the two together ✅

    • @corinav8193
      @corinav8193 Рік тому +2

      So how much time should there be between taking NMN and taking TMG? Thanks for helping out!

    • @lynnsanelli1838
      @lynnsanelli1838 Рік тому +2

      @@corinav8193 donotage company told me it can be taken at same time or later in day as long as it's sometime that same day.

    • @semaaral2498
      @semaaral2498 Рік тому +1

      Someone said me to take it any night before bed.
      So shall I take it with NM or Resveratrol?
      Thank you 🙏💊💕🔬

    • @lynnsanelli1838
      @lynnsanelli1838 Рік тому +2

      @@semaaral2498 NMN should be taken first thing in morning to enhance workouts, energy, etc. You can take TMG anytime during the day -- with NMN or later in day

    • @michaelmcallister5522
      @michaelmcallister5522 Рік тому

      If taking just glycine will I also need to take TMG if taking NMN?

  • @markfischer3626
    @markfischer3626 Рік тому +12

    Two other substances are needed to assure the salvage pathway for NAD+. One is an NAMPT booster. R-alphalipoic acid (R is the natural form) or quercetin do this. I take both. The other is the CD38 blocker Apigenin which I also take. L-Leucine taken without any other amino acids and also not with other BCAAs isoleucine and valine boostes the effect of NMN and resveratrol. I take that to along with 100 mg resveratrol every other day. I also take 1000 mg AKG every day along with the others. AKG may be the best possible fuel for making ATP and squalene, precursor to many hormones. It's just one step away from the last molecule before exiting the Krebbs cycle. NAD+ catalyzes the reaction of AKG to Succinyl Co A. That's the molecule that leads the path out. The entire point of the entire pathway starting from glucose or whatever other fuel you use to get a high energy electron to turn ADP into ATP. This is the power that drives practically everything else. It's made in the mitochondria. Maximizing mitochondria and their production is currently a very important factor in the path to good health and longevity. There are possibly others but this one is critical.
    Fasting or OMAD and MCT especially C8 appear to be very important too as do polyphenols derived from plant based foods. Blueberries are among the best. Other dark berries like blackberries and even strawberries and red and black raspberries are very good too. The powerful antioxidant glutathione is made from NAC and glycine in the liver. Taking it directly gives poor absorption. Melatonin and L-tryptophan are also useful for making NAD+. Taurine is now discovered to be essential too. I take all of these (not taurine yet) and many more.
    What do you think of Sirtuin 6 activator? Only one known safe source. Rather expensive.

    • @BK-dy8jk
      @BK-dy8jk Рік тому +3

      Holy cow how do you know so much of this? I know only a few of these and thought I was really something but you blew me away. Love to talk to you more about things since you really seem to know your supplements, you get a A+.

    • @ladyfame1430
      @ladyfame1430 10 місяців тому

      I said the same thing holy cow do you work for one of these companies lol just kidding I appreciate your wealth of knowledge

    • @AbuPaponette
      @AbuPaponette 5 місяців тому

      He you need to give a us a course or something, we need your information

    • @bperez8656
      @bperez8656 4 місяці тому

      All that work
      All that taking
      And what tangible effects have you noticed ?

  • @lindaallen2412
    @lindaallen2412 Рік тому +10

    Yea all very well but if he and his FDA friends have their way we won't be able to get NMN

  • @garyshields2734
    @garyshields2734 Рік тому +2

    Really interesting. I'm thinking that people in dialysis, might have improved kidney functions with increased intake of methyl, via TMG for the kidneys. I don't know, if that would work, be harmful to the kidneys, under these conditions or not.

  • @arsononemwv
    @arsononemwv Рік тому +7

    im 28 and looking to age well. Am I wasting my money taking NMN / TMG at this age? I weigh 146LB and I am 5'10

    • @BK-dy8jk
      @BK-dy8jk Рік тому +1

      Well, at this age, you’re still doing great and won’t need much of this until maybe after 35. Could take a small dose 250 MG but I doubt you’ll notice anything yet.

  • @charlescino8273
    @charlescino8273 8 місяців тому +2

    Instead of taking NMN, why not just take Niacin (flush) ?

    • @WellnessMessiah
      @WellnessMessiah  8 місяців тому +2

      Hi Charles, yes Go to minute 4 I think where I speak about niacin in this video:
      ua-cam.com/video/odAULo1atVs/v-deo.html

    • @Delta-V1
      @Delta-V1 6 місяців тому

      How to know Niacin is flush?

    • @abdulwaheed-sq8qy
      @abdulwaheed-sq8qy Місяць тому

      @@Delta-V1 after taking nicin skin turn into burn redness very hot ear

  • @C21agent1
    @C21agent1 Рік тому +2

    What are the dosages for NMN and TMG I’m a female 63 years old 150 lb

    • @BK-dy8jk
      @BK-dy8jk Рік тому +1

      Well, I would start low and maybe move up after a month to 1000mg a day each and take a Sunday break.

  • @ricklopez4703
    @ricklopez4703 6 місяців тому

    Are you saying we have access to Supersoldier Serum 🤔

  • @chuklhed9092
    @chuklhed9092 5 місяців тому

    Does anyone take TMG without working out? I’ve seen studies that show it only works with really intense exercise.

  • @Amanda_Blair
    @Amanda_Blair 5 місяців тому +1

    What is a good NMN for people who are poor lol. I want to be healthy and age well but don’t have the funds for super expensive supplements

    • @WellnessMessiah
      @WellnessMessiah  5 місяців тому +1

      Niacin. check my explanation here:
      ua-cam.com/video/5Ps6Jet1D1Q/v-deo.html&lc=UgzC6QUF8AqkcRYRHlN4AaABAg

    • @Amanda_Blair
      @Amanda_Blair 3 місяці тому

      @@WellnessMessiah thank you 😊

  • @ElK.-qv4ol
    @ElK.-qv4ol Рік тому

    how much tag goes he take, and does he do this daily ?

    • @SAMSAM-rw9fc
      @SAMSAM-rw9fc 10 місяців тому

      I have become crazy to decide which NMN should i take btw im a mature person,any suggestions of the brand, please?

    • @MarieLamour-cv1jc
      @MarieLamour-cv1jc 5 місяців тому

      @@SAMSAM-rw9fc Renew by science. Unsure why anyone cares if you're mature.

  • @dapolcio3405
    @dapolcio3405 10 місяців тому +4

    NMN is overpriced. NMN is broken down in the stomach into niacinamide and ribose. It is much cheaper to buy niacinamide and ribose and take them together.

    • @GlossaME
      @GlossaME 10 місяців тому +2

      If I take Niacin (flush version) , do I get the same benefits as Niacinamide? Roughly 3 grams per day

    • @dapolcio3405
      @dapolcio3405 10 місяців тому

      I've read somewhere that all b3's boost NAD but too much blocks some enzyme or something that produce it. Usually 100-150 mg 3 x day of niacinamide is all you need to boost NAD. I don't know if the same amount applies to niacin@@GlossaME

    • @Delta-V1
      @Delta-V1 6 місяців тому

      ​@@GlossaMEhow to know wjich niacin is flush version ?

    • @GlossaME
      @GlossaME 6 місяців тому

      @@Delta-V1 make sure it's not called NIACINAMIDE. It should be plain B3 NIACIN. You'll know when you take it, within minutes.

    • @xp75
      @xp75 3 місяці тому

      @@GlossaME

  • @pjaworek6793
    @pjaworek6793 Рік тому +3

    So, "it's probably not doing anything". Well at least it's cheap.

    • @arhu74
      @arhu74 Рік тому

      doesn't taste bad either (it actually tastes pretty good)

    • @dune7824
      @dune7824 Рік тому

      lol yeah I'll save my money. Buying something cheap for no benefit doesn't make much sense to me.

    • @myhanslombard
      @myhanslombard Місяць тому

      @@dune7824 Try it, it really changed my energy levels, like x 10. With TMG

  • @gloriagolemboski4515
    @gloriagolemboski4515 Рік тому +1

    Is he married to Sarina now. I heard him say he had a wife and wears a ring.

    • @SAMSAM-rw9fc
      @SAMSAM-rw9fc 10 місяців тому +1

      Focus on how to look a teenager by taking NMN after David comes to you himself to propose to you regardless he is married or not ha ha