Hormone replacement therapy (HRT) and the heart
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- Опубліковано 26 сер 2024
- The arrival of menopause can be particularly distressing both mentally and physically. A number of conditions are associated with menopause. These include hot flashes, an increase in incidence of osteoporosis, alzheimer’s, vaginal atrophy and cardiovascular disease. At the beginning of the 20th century, the FDA approved an estrogen replacement medication called Premearin for the treatment of hot flashes.
In the 1970s, it was found that unopposed estrogen therapy was associated with an increase in endometrial cancer and HRT became unfavourable.
Subsequently however researchers found that if the dose of estrogen was reduced and combined with progesterone then the risk of endometrial cancer was reduced and once again HRT in the form of combined therapy (estrogen and progesterone) became popular again.
In 1988, the FDA approved HRT as a treatment not only for hot flashes but also for prevention of osteoporosis. As confidence and usage increased, researchers became interested in cardiovascular disease prevention.
We know that the incidence of cardiovascular events increases in post-menopausal women. This was shown nicely in the SWAN study which found that in women with hot flashes, there was a higher incidence of sub-clinical cardiovascular disease which included more calcification in the walls of the big vessels in the body (aorta) compared to women without menopausal symptoms. GIven this observation, researchers became very interested in trying to work out whether replacement of hormones by giving patients HRT could in fact prevent or arrest the sub clinical cardiovascular disease and in some way prove protective.
A bunch of observational studies did in fact suggest that this could be the case and doctors became very interested in prescribing HRT to women to reduce the risk of heart disease.
In 1998, a study was undertaken to better study the effects of HRT on the most common causes of mortality and morbidity in women such as cardiovascular disease, cancer and osteoporosis. This was called the Women’s health Initiative study.
16608 women with intact uteruses were given either a combination of oestrogen and progesterone or placebo and a further 10739 women without uteri were given oestrogen or placebo. The results were published after 5 years and claimed that in women with intact uteri, there was an increase in coronary disease and breast cancer but there was a reduction in osteoporotic fractures and colon cancer. On the basis of these results the trial was stopped prematurely and the message sent out was that HRT was a bad bad thing and there was a huge drop in HRT prescription.
In the group of women without uteri, they found that there was a small increased risk of strokes and there did not appear to be any benefit in terms of cardiovascular risk or breast cancer (but there was no increase risk either) but again there was a consistent beneficial effect on osteoporotic fractures and colon cancer. Nevertheless the overall message still remained that HRT was not such a great thing and it could be used maybe sparingly for osteoporosis and symptoms relief (from hot flashes) but should definitively not be used in asymptomatic women.
Please watch the video to find out the rest
Watching what happens to your body with no estrogen...as you go into old age...is devastating...far beyond disliking hot flashes. Hot flashes are nothing. Take HRT. Change diet to reduce heart disease...but don't give up your estrogen. I'm in my 70s. HRT is ONLY thing that has arrested osteoporosis. Before HRT I lost 2 inches in height. This changes everything inside the body. Without estrogen the brain changes. HRT means so much more than an antidote to menopausal symptoms.
betzi b 💝💝💝💯🙏
I feel similarly. Women that don't have severe menopause seem to sometimes think others are giving in ... but severe symptoms are devastating. As soon as I started HRT, my so-called fibromyalgia and hip bursitits (that had haunted me for 10 years) stopped. I started sleeping through the night. My IBS stopped. And of course, the other devastating symptoms associated with severe menopause. As soon as menopause started, i felt like my brain was actually being attacked and I was 100 years old. HRT saved me, literally. I have Afib and heart disease in my family not breast cancer so I would prefer to stay on HRT as long as needed. Living life without it , was no life at all, for me.
@@mishca5116 no family history doesn't mean u don't get cancer 😂😂😂😂, just need a trigger
@@BlackMamba-lt8oe i didn't say it did prevent me from getting cancer. It is a matter of personal risk assessment. I am quite aware that no family history doesn't mean you are at no risk for bc. Again, everyone has to make decisions on their own personal situation.
@@mishca5116 I agree. Life without it seems so full of inflammation that it is hardly worth it.
This is my story. Only saying what worked for me. At 41 I went through menopause, my first worse symptom was memory loss and depression and as a nurse I was devestated and frantic to say the least. That was in 1982 . Thank God I had a doctor who recommended hrt. I also used progesterone for a few years then quit that as I didn't feel well with it. I did have a hysterectomy around 55 . I'm now 791/2 years of age. Good memory, no depression , no pain anywhere , thank you God. I've done hrt for 38 + years at a small dose .125 . This worked for me, I can't say for others. My quality is so much more I feel than it would have been. My present gynecologist has no problem with me taking the med because as he said since I'm a small woman I would need something for bone loss, depression , and maybe pain med as time went by, all of which have a list of adverse reactions , so I would be taking 3 at least meds with side effects vs 1 med with potential side effects.
This is my story only. As a side my daughter is 60 no hrt is shrinking and has some slight anxiety / depression and alot of painful joints esp her back.. she didn't feel well on hrt . Would it have made a difference? Who can tell. Good luck and good health.
Maybe she can try red clover for estrogen. It's the only source of estrogen that only gives me the good effects and none of the bad. I also like fenugreek for testosterone (rarely need it) and damiana for progesterone.
@@koalamama2 thanks so much. God bless
I have had the same positive reactions as yours...am 78..which is unbelieveable to me! I still "feel" i benefit from a very low dose 37 mg...who knows? I sincerely do "feel" so positive about this.....
Do you take estrogen in pill form or topical application?
Thanks so much for this video! I'm about to start taking HRT and hoping it will make a difference. My sister has been taking it for a year now and has just started experiencing heart palpitations and has increased BP. She's always had low HR and BP, eats very healthily and exercises regularly so this is unusual for her. Hard to work out whether the HRT is causing palpitations, high BP (these can be side effects) or if her symptoms are due to low estrogen (does she need her dose of HRT increased?)....or is it totally unrelated. It's a minefield 🙈🥴
I wish more doctors were like you and keen to educate themselves.
I was told i can't have HRT as I had a heart attack 14 years ago. That was the end of the conversation. I'm now 54 and through the menopause. It was a nightmare but nightmares like all things end eventually. Thankyou so much for talking about this subject. It's interesting and extremely helpful to so many people. You're a very kind person.
Being a woman with heart attack? Definitely have genetic factor so yeah not a good idea
@@naegleriafowleri2230 How do you know it's a genetic factor???? Are you a doctor??????
You look great with the beard! And you’re gifted with eloquent speaking. This topic was extremely useful for me. Thank you for all you do for us.
As I have studied BHRT I thought i'd add some more information. The Women's Health Initiative trial was NOT based on natural Progesterone it used a synthetic Progestin. Progestin's have been found to be extremely onerous both in promoting breast cancer and heart disease. It is imperative that a natural progesterone is used combined with bio-identical oestrogen. With regard to oestrogen, countless further studies clearly show that replacing E2 (estradiol) and E3 (estriol) a much weaker, but breast cancer protective oestrogen combined, with natural progesterone is the safest possible replacement (unless like you said there are contraindications or previous breast cancer or heart disease). E3 has actually been used currently in trials and is thought to have a similar effect to tamoxifen so it works almost like an anti-oestrogen on the receptor sites. It is also VITAL that oestrogen is ONLY administered transdermally. Progesterone can be oral. This bypasses the liver. If vaginal dryness is the only problem E3 can be used internally via pessary, etc, and can be compounded.
Perfect. Absolutely agree with all you have said here! 😁
is vagifem E3 please?
Valuable info. Thank you!
This has been my experience, as well. I've been on BHRT since 2006 and am still on it. I don't know how I would have managed without it. Although I was fit and healthy, after going off birth control at age 40 I had wicked early onset menopausal symptoms. I will be forever thankful that BHRT was made available to me by a very caring and knowledgeable doctor. My mother had been prescribed Premarin when she was in her 50's (30 years ago) while going through menopause. She was one of the unlucky ones who was later diagnosed with breast cancer several years later. There was no history of cancer in our family. Fortunately she survived the experience but I remembered the HRT controversy from back then and was determined go a more natural route. What a blessing it was that bio-identical hormones became available just when I needed them. I really feel for women who haven't had this opportunity and were left to suffer. My symptoms were relentless and exhausting. Thank you Dr. Gupta and Body360 for sharing this critical needed information!!
Probably one of the best summaries of HRT and CVD. Thank you Dr Gupta
I had debilitating, embarrassing hot flashes, multiple per hour. They went on all night with sweating, insomnia, chronic uti and bladder infections. I thought the bladder infections might kill me. I felt horrible. The hot flashes literally stopped within hours of the application of the estrogen patch. I also take oral progesterone 12 days per month.. No more uti's, sleep like a baby. I've been on it 4 years now and never want to go off of it. It's been life changing for me.
Dr Gupta, I just found your channel. You rock!!!
Thank you for taking the time to share your knowledge.
Thanks so much for this video. I’m a nurse and I love watching your videos because to be a good RN you must always be learning. That being said, this one was perfect for me because I went off Estrodial last year; exactly a year ago after my dr told me I’m nearing 60 and need to come off if. I am 57, had a hysterectomy at 40 due to anemia r/t fibroids and I have terrible hot flashes, sleep disturbances, moody and have brain fog. When I first went off it I was fine for a few weeks. But now it has become Unbearable! I’ve read different things So I was so happy to see you had this topic!! I have a MD appt next Tuesday to discuss going back on and now I feel armed with knowledge which was really broken down simply. Thanks again!!
Luv the new look, your site is exceptionally helpful!
A long time ago, I was in CV pharmaceutical research and I love to keep up with the scientific literature. This is such a clear, interesting explanation of the studies about the effects of HRT, especially about the age/distance from menopause.
What strikes me is that, while the natural state of hormones is cyclical and the dosage of Premarin is evidently 3 weeks on, 1 week off, if the estrogen and progesterone are combined, there is no way to separate the cycles of each. Best case scenario would be to try to replicate the natural sequence and also the natural estrogens in the body, which horse urine does not do.
I also wondered why certain female traits increase with menopause. Don't we have a decrease in estrogen? Then I discovered that the ratio of progesterone and estrogen is more important than the actual levels and that progesterone decreases the 2 years approaching menopause, before the decrease in estrogen. Therefore, the P/E ratio decreases, causing those premenopausal symptoms like weight gain.
I also had the privilege of working with chicken farmers. Those white chickens are CornishX, bred to be estrogen dominant. When fed soy (estrogen), they become fat on very little feed. Even if given access to the field, they are too lazy to forage and just sit around eating all day, gaining weight so fast that they have heart disease and even broken legs by 8 weeks, at which time they are 8 lb dressed weight. If fed without soy, but with protein like fish meal, they are only 3 lb dressed at 3 weeks, yet eat more.
I identified with the estrogen dominance and changed my diet and lifestyle. Menopause at 58 with no big issues. Instead of controlling symptoms with drugs, I've learned the the first action should be to be healthy. Detox (yes that is a necessary physiological process) and eat healthy and move.
I’m glad you found what works best for you. My husb is a data consultant w/clients incl commercial chicken farmers and large feed mills he’s analyzed data on growth patterns and many factors involved. Good meta analysis show benefit of soy to women incl menopausal. Most fish incl ‘wild’ now carry pesticides and micro plastics in their system esp fat. Farmed fish often escape and taint wild areas (watch Artifishal doc film) I’ve been vegan whole food plant based for yrs. Menopause symptoms are min and weight stayed at/below healthy BMI range naturally w/o any effort. My husb same is in no medication at the age of 70 plus the blood work and every of those half his age. For me after yrs of studying data and quality studies and found vast bal of it not funded (directly or indirectly) by food industry like meat/dairy/fish/poultry all very powerful lobby juggernauts to govts and WHO show plant based diets incl soy and phytoestrogens to be the best at lowering all cause mortality and (only) at reversing CVD. I’m a student not a follower and look at many diff sources and who incentivized them, ie I don’t automatically believe a vegan MD over a non. Dr Kim Williams cardiologist does have some excellent talks and videos. I respect everyone’s right to look at the info they find and decide for themselves. Many blue zones do eat some animal protein (less then 10%) and soy. More studies are showing our unique microbiomes play role in how we process food, drugs etc. We’ll see what good quality (independent of big pharma) studies show. Women like us have seen good health is key - however we get there. Best wishes.
@Connie Eash
Thank you so much for your post. I had been watching other videos recently of how soy has become so dominant in the American diet. It's virtually in so many, many products. From what I've gathered it surely seems to play a major role in America's obesity explosion starting in the 1970's. Also with males developing female traits such as breast tissue. Thank you again for your info!!😉
You posted a video some time ago regarding magnesium and the benefits for the heart. I researched the subject and found that it was thought to be a good remedy for menopausal hot flushes too. I am 58 years old and had been having flushes quite regularly (particularly at night) so decided to give it a try. As far as I am concerned it seems to have solved the problem. I was taking magnesium tablets for about 1 week before I noticed any difference, but do feel better now. I never liked the idea of having HRT so if anyone else is a bit wary, it might be worth trying magnesium tablets as an alternative.
Magnesium for the Win!!!😉 I use magnesium to help keep my heart rate calm and to feel relaxed and sleep well. My body chemistry seems to looove this mineral!😉😎
Amazing! There are many types of magnesium, which type did you take? Magnesium citrate?
@@AdelleRamcharan I take Magnesium citrate and it really help me.
Hi Gillian, thank you for sharing your experience with magnesium. Could you please let me know, which form of magnesium has helped you? I know your comment is from one year ago, how are you doing now?
@@AdelleRamcharan Hello, Sorry I have only just seen your reply. I take 2 Magnesium Glycinate tablets before bed. Hope it helps you.
I found hrt very effective in eliminating hot flushes. I'm 58 and I've been on it for 3 years. No hot flushes any more but i continue with one low dose patch per week as I feel it might be effective against osteoporosis. Thankyou for the video, as always.
Thank you ! I went into full menopause at 44 had pedi menopause at 39 and was told HRT was bad but the riisk of all that you said in this video was so high for me . Nearly 2 years ago after suffering everything you could think of , my well being turned up side down a cousin of mine suggested bio identical natural hormones and I’ve been on them for 17 months and they have changed my life !! Hot flushes gone , heart palpitations gone , anxiety gone , vaginal dryness gone . I even got oestopiana , which is scary . I restored my well being and reduced my risk of dying of other things . Know I do bone building classes so I don’t lose anymore bone and have protected my self as much as I can from the effects of menopause .
Wow! Do you take estrogen and progesterone or only estrogen?
@@marsha2875 yes I take both and a little testosterone. Honestly the best thing I did .
Can HRT cause Cataracts ?
@@jacquelineelmawey2669 how much T do u take and is it a cream which is compounded.ty
@@MS-sr1fe I take 10mg of testosterone with 0.25mg oestrogen in a trouche that dissolves inside your mouth
Oh wow... Thank you so much doctor🙏 for all this easy to understand information on hrt and menopause... extremely helpful and I now know the pros and cons of hrt... You're too brilliant and a wonderful soul👌👏🙏. Take care and God bless 🙏
In my opinion starting body identical hrt at 50 is the holy grail. I'm staying on it forever. I'm 55 now, life without it was upsetting in many ways. I had all symptoms doctor mentioned above. I'm so grateful its available as I can live a normal life again. Body identical is Utrogestan micronised Progesterone & Estradiol Sandrena transdermal gel.
I'm not going to suffer as it won't get better just gets misreable and older. 🙄
Do you feel estrogen pill or cream is safer?
I’ve been on HRT for approximately 15 years age 52…. Now 70 and continue using them . My doctor does nothing but the BioTe pellets and tells me testosterone is very good for my heart . Not only for my muscles but my heart and strengthens heart “ muscles “ . I am grateful for additional benefits from it since I had horrible hot flashes. Alzheimer’s runs in my family and I’m osteopenia… I have cardiovascular disease and had a double bypass now 3 years ago . All the while staying on my hormones minimal lapses. I 100% agree with the quality of my life and have no menopausal symptoms or anything else . Refuse statins and am very grateful for finding them . Thanks for the video it’s very reassuring . Love your videos keep them coming
Bio identical therapy made my hair and my sisters hair fall out. Premarin made me sick plus animal cruelty. Estrace killed my mom with ovarian cancer. I’m eating vegetables and organic turmeric. Hot flashes are minimal. Sweets and alcohol are really bad and cause night sweats. Thank you Doctor. Stay away from stress! Happy Thanksgiving everyone.
@L.M. Wallace Almost no one prescribes Premarin anymore. I think if you have been on it for years and are resisting change you can, but everyone else is on body identical oestrogen in the form of gel, patch, spray or tablet and either body identical progesterone Utrogestan or a progestin if they prefer. No need to pay a fortune. It’s all available on the NHS.
Premarin is not bio identical....and the right dosage would not have caused hair loss.
Dr Gupta you are the best! I so wish i could have you or someone like you as my dr.
Thank you for this information it is truely appreciated.
Thank you Dr Gupta, yet again, another vital explanation of important health information.
Yes! This information was extremely helpful! Thank you for posting! And I love your shirt 😁✌
Very timely, with the current establishment of a menopause charity in the UK; this subject is all too often ignored by GPs, and the effects of menopause are generally not considered or kinked to other health issues. For example, i have read that more post-menopausal women die from heart attacks than from breast cancer. If this is true, then we need better education. Thank you for addressing this
Die of heart attacks how ,estrogen is protecting them
I was having many palpitations every day and this was the worst symptoms for me....I was in and out of the hospital...hrt has really helped with this
How long were you on HRT until your palpitations went away?
So good to hear from someone that does a lot of research, and talks to us with inteligence. It's always hard for me when someone calls heart problems CVD, because there's a lot that can go wrong with the heart. The most common problem is clogged arteries, all the way to hearts that don't beat right. What does HRT do to the heart to affect it negatively? Clogged arteries can be avoided with a low fat diet and exercise. Other than that, exactly how does the HRT affect the heart. Thanks for helping to inform us.
Absolutely brilliant topic and thanks for yet another fantastic video. Really appreciate all your efforts to educate people.
Yes, estrogen is great for heart, bones, brain, joints, skin, mood, vaginal issues, bladder health, etc. Quality of life after menopause is quite bad for many women, estrogen improves quality of life significantly. There is a small but significant increase in the risk for breast cancer. But I keep remembering what a doctor said to me--without HRT if you have a heart attack after menopause you have a 50% chance of dying. With HRT, there is a small increased risk but if you get breast cancer you have a 10-year survival rate of 84%. Risk/benefit decision.
Good video! Glad you are well. Nice "pandemic beard." Thank you for all you do!!
Thank you for clarifying the reality of HRT.
The menopause is not a joke, it is not a process that everyone finds easy to go through, and it's effects can be devastating physically and mentally-and by no means limited to hot flushes.
So many women are suffering needlessly and losing their quality of life, due to outdated research.
I really appreciate that you took the time to learn more about this issue, and are giving it the level of importance it deserves. Thank you Dr. Gupta!
I'm on hrt bio identical pellet..I'm 70 and feel great..
Thanks doc!
I've had hrt now on estrogen only.
Had fracture of public rami.sum
Really helpful to analyze the results and make some sense of why doctors do what the do. I was in this situation. Now I understand the decision the doctor made to use HRT only for a limited time. Takes a lot of skill to analyze the results. Thanks you!
Very clear and concise explanation . Brilliant and thank you.
I had a TAH back in jan 2013 at the age of 53, for 2 years I tried to get by without HRT but eventually being totally miserable all the time I begged my GP for help, a couple of non HRT options were tried but made me feel spaced out, so eventually I was prescribed estradiol 1mg, a few weeks later I felt ‘normal’ for the first time in years. I have been on this ever since and dread the time when I have to stop taking it, I rarely get hot flushes, I did gain about 40lbs, however 2 years ago I started a clean keto program (no grains, sugar or highly processed foods)and have lost all of the weight I gained and some besides.
I take 400mg of magnesium, vitamin b complex and vitamin D daily. I haven’t felt so healthy for over 20 years, I only get IBS flare ups when I accidentally eat wheat and rarely get reflux anymore.
I have found your videos incredibly informative and am using your information to tweak my nutrition so be the best me! I just need to increase my exercise and I’m hoping that I will have nailed it! Many thanks and keep well.
Helpful. Please keep ur coming especially HRT for over 60 yrs old. Thx
Go and read the marvellous web site www.menopausedoctor.co.U.K. Full of up to date information. Talks about older women as well as young and has a regular podcast to listen too as well as videos. It’s an excellent resource.
Thankyou So much for covering this topic which is often not talked about and is going to affect every woman on this planet. Ty for sharing doc. Tc
Thank you so much! This gives me some peace of mind!
Your help revakidate my own experience with hrt. I am one of those people started hrt right after onset of menopayse. I am 76 years old on vivelle-dot 25 -the lowest dose which is still safe and effective. Thank you.
Very thorough discussion and so helpful to me. Being past 10 years post menopausal and a history of a PE, I am sad that HRT is not for me.
Thank you for very informative video👍 you look better then ever.
I was on HRT for many years in my Forties for Hot Flashes, night sweats, etc., which was minimal for me. I was more concerned with what it did for my skin, hair, etc. I've never had female problems. My period only lasted one or two days while most of my friends were 5-7 days. At the time I was concerned so I asked my doctor but he said to consider myself lucky, as long as it came regularly, I was fine. To this day, I've never had any female problems. I got pregnant, gained 18 lbs, had two hours labor and went to the beach after two weeks and back to work after three. Health wise, I've been very fortunate. I hardly ever get sick, not even colds and flu. Its January and I haven't had a cold or the flu this winter. Did not have the COVID vaccine, mainly for fear of blood clots while I'm taking a blood thinner. My family history is one of death by heart attacks, strokes and my sister had a blood clot in her neck that traveled to her brain and she died. I am afraid of blood clots and heart attacks for I feel its my destiny.
Bio identical hormones helped relieve my POTS symptoms (what I thought was POTS, but a tilt table test was negative. I also have M.E). I was prescribed HRT for severe PMT. The cardiology nurse said that because I responded so well to HRT, it showed that my POTS symptoms were clearly hormone related.
Was this because you had adrenal weakness in menopause? Did they ever test your DHEA which is a precursor hormone to testosterone and oestrogen but produced by the adrenal gland. Often people with POTS type symptoms have adrenal weakness/fatigue.
I can't believe I just read your post about this. I know it's been 2 years, but I truly think you are onto something here... dysautotonomia and peri/menopause symptoms! Thank you!!
Thanks so much for taking time to educate yourself and us on hrt. I’m facing the dilemma of what will suit me best
I wish I watched this 6 months ago . I'm starting hrt tonight. I'm in hell with hot flushes,vaginal dryness,headaches etc. I'm 47 and feel optimistic now after watching your video. Thank you so much
Thank you!!! This has been so helpful in figuring out if HRT is right for me. I'm not symptomatic and bloodwork shows I'm heading into menopause. I appreciate your very detailed explanation. Wish we had more doctors like you. Stay safe.
Brilliant video, thank you.
Thank you for your explanation of HRT.
It's very helpful.
I was prescribed HRT by my male doctor when I was 47. I am now 68 and been taking it for 21 years. I feel great, I am fit well and very active still running my business. I only eat whole plant based foods also which I think is the best diet to keep us healthy. All diseases stem from animals. I’m staying on HRT till I die! 😃😃
Actually all disease stem from poor diet, mainly high carbohydrates which leads to insulin resistance and that sends your body into a meltdown. Some plant based diets are high in carbs with all of those pretend meats. Best thing is to do what works for you and not blame place or shame people due to your beliefs. We should operate in facts , not feelings.
@@umayaswellcallmejesus1489 I was not shaming or blaming anyone! I speak from facts I do now eat fake anything only natural plants. Do some research and educate yourself. Look up Dr John McDougall, Dr Caldwell Esstlystene, Dr Michael Gregor.
That reads DO NOT EAT FAKE ANYTHING!
@@chrissiewilding6074 I am educated, and I do research that’s why I made a factual statement.
Not all diseases.stem from animals. Deficiency of B12 can cause disease.
such a tough one.Im 5 years in and 59 and if i thought it would help my heart at all i would have taken it as there are so many things about the menopause that make me miserable. i wish i had known this sooner
Thank you. I am 66, and I STILL have flashes, though they are greatly mitigated by my bioidentical HRT regimen. I definitely feel disapproval from most of my doctors (all in the same medical system, and one of them is a ob/gyn, though not a menopause specialist). But I've heard conflicting views from people who ARE menopause specialists. I take minimal doses of bioID progesterone and transdermal estrogen, and am much more comfortable because of it - better sleep, etc. Appreciate your balanced take. Stay safe!
so even the menopause specialists disagree ?
@@annehaughton3968 No, my observation is more like non-specialists are still clinging to outdated research.
Excellent video. Very informative. 👍
How about evidence of a whole food plant based diet on hormones and the benefits of overall health. Sy
There’s literally 1000s of studies now showing benefits incl lowering of all cause mortality. Search Dr Neil Barnard for hormones and Dr Kim Williams cardiologist/past head of ACA. Also watch Forks over Knives, Food Matters, What The Health, Eating you alive, Plant Pure Nation. They’re all very well researched and show truth about food industry esp meat/dairy/poultry/fish and their power over govts, govt orgs and legislation etc. Artifishal is doc film on fishing industry. Decide for yourself after taking time to look at all info. Best wishes.
One Review of studies:
www.nature.com/articles/s41398-019-0552-0
nutritionfacts.org/topics/hormones/
Excellent summary thank you!
Very well explained. Thank you
The best information every where 😊
Glad it was helpful!Thank you for your support- it would mean a tonne if you’d consider subscribing to the channel.
Also I try and do some regular broadcasts via WhatsApp on +44795131008
Excellent summary....
Thank you! This video was very helpful.
Glad you delved into this controversial subject ~ iT Affects Everyone ~ all of us out here in the frying pan are begging for solutions! My wife, after 50, is encountering these issues. She has fibroids, cysts, and having heavy bleeding issues which thrust us into the er for transfusions. Gynecologist is young and really mainly delivers babies. Been on a roller coaster ever since. some Dr recommend Hysterectomy but refuse to operate due to Heart. Can you do a Vid on having surgery (like a Hysterectomy) and it’s implications if you have Heart Disease and What you should do to try to get the surgery that you are in need of!
I’ve been using Premarin vaginal cream for 16 years (.5 mg every 5 days. Because I had breast cancer I am vigilant in testing the thickness of my uterus lining as that, according to my gynecologist, gives an indication of uterus cancer if it thickens, I’ve been ok so far. Thank you Dr Gupta for letting us know the benefits of taking HRT such as strengthening bones, which I totally agree with, as a 74 year old that has fallen a couple of times but didn’t break a bone😃. But the main reason I take it is to avoid urinary incontinence which is the best benefit for me.
Great video Dr. Gupta. ❤️
Hi there, this is an important topic for me right now. I'm 50 and thought I was breezing through Perimenopause but things have taken a turn. I have developed severe arthritis in my toe (although the Dr says no evidence related to MP) also knuckles on my fingers deforming (though not picked up on X-ray) I feel, at least with the fingers there may be a link to oestrogen decline ?
I've also started having hot flushes. However I am anxious about taking HRT, I was considering going on it for a short amount of time, but worry I will get too used to it or I will get breast cancer. Even with the risks explained, there seems so much room for doubt, it seems to be a gamble. However I am leaning towards it for a short term remedy.
I wish there was even more research as it's so difficult to make a decision.
God Bless you. I suffered a lot during menopause and instead of hormones treatment dr have me medicines for depression
At that time I had no idea of depression at all. I was told to take it for 2 to 3 months
But it went on for more than 7 yrs now. I am still struggling.
Have you kept a diary of what you’re doing/eating when you get hot flashes? I tried HRT for one month Premarin, found out it was made from pregnant mares, grossed me out so bad I stopped taking it. Looked for holistic ways to help. Found out starchy sugary foods were my enemy , gave them all up and no hot flashes since. Of course I eat clean and exercise to increase serotonin and support my adrenal glands. It’s a process but no man made pills involved. Hope this gives you a starting point to figure out a better way for you !
@@umayaswellcallmejesus1489 . Thank you very much for your advice. With me its connected with the feeling of hot flushes , lot of fear, anxiety and weakness. Food I prefer to have light food with more of fruits and vegetable juices. Used to do regular yoga and breathing exercise .
I highly recommend Dr. Louise Newson’s excellent website menopausedoctor.co.uk or Barbara Taylor’s menopause videos here on UA-cam. Knowledge is power. You can be helped by an up-to-date menopause specialist! You deserve it. Good luck!
Oh wow I am so thankful for this video and all the info. I just turned 50 and going through menopause. I was contemplating over HRT but your video helped make the decision a lot easier. Thank you again. Love all your videos 🙏
HRT patches are allowed if previous blood clots. Just not oral.
You are exceptional !
Red clover is excellent for relieving hot flashes as well as aiding heart and bone health.
Red clover does zip for bones. I could 've planted several pastures with all the red clover I took. Hot flashes are nothing. Soy can help. But you can stuff down all the clover and cohosh you want (the latter causes uterine hypertrophy by the way) and those bones just leak out like your body is a sieve...and vegan...alkaline...nada. The harsh truth is nature needs you around to get your young to the age of procreation..then you can disintegrate and get out of the picture. End of story and your vacancy on the planet makes a place for the next young mother.
Red clover causes endometrial hypertrophy ( overgrowth) as well as solving the hot flushes.....
Really! The studies I looked at showed no change in endometrial growth.
@@krsnadd9106 I dont know about red clover but the study on black cohosh was reported in JAMA but it was over 20 years ago so maybe subsequent studies dont support that. However my guess is that we aren't lucky enough to find an herb that only activates healthy bone growth and doesn't activate other receptors in breast and uterus. If there is one...i sure want to know what it is. Many things affect study results and interpretation. So we really need a source of reliable info. We need a Dr. Greger for women
@@krsnadd9106 Happened to me.....it's oestrogen (phyto) and so will grow an endometrium, that's what oestrogen does after all.
Thank you for this.
Thank you for your videos. Menopause night sweats and palpitations/ectopics, sleep deprivation are life ruining symptoms, sadly I can't tolerate any form of HRT.
Hi Dr Gupta,
I noticed that this video was uploaded a year ago. I’m hoping there is a chance you would have perhaps since heard of Louise Newson GP. She has made many UA-cam videos on the subject and is known as the Menopause Doctor. She has her own clinic, a free help app called ‘Balance’ and is a rather well known authority on the subject. She has made many appearances on TV programmes such as This Morning.
Always Like your videos very informative also your new look Doc 👌
Hi, love your videos. I get more information from your videos about my current Afib and heart failure diagnosis than from my doctors. I have a question - why can't you stay on HRT if you are diagnosed with early stage heart failure. What are the risks of staying on HRT with heart failure. Thanks in advance.
I find it bizarre that this vlog on HRT relates only to women
Progestin is synthetic. Progesterone is not. Premerin is synthetic hormone.
Interesting information thank you. I’m sure there are many women like me who are interested in the effects of estrogen on the heart and heart function if you could give us information on that.
Very helpful. More if possible on using HRT patches in women over 60. Anything on menopause and ectopic beats?
I would like to know if there are any cardio vascular implications to coming off HRT?Thank you
I am sorry to say but i have developed etopics for the first time when i tried to stop hrt. Once back on it, the etopic beats disappeared...
I’ve had hot flushes and sleep disturbance now for around 15 years. I had a short spell of hrt patches during peri menopause and it sure did help. I was taken off hrt for fibroid investigation and told the hot flushes wound die down eventually. However they didn’t! I’m now 65. Still have sleep problems and hot flushes. Not recommended for hrt as I had breast cancer 6 years ago. I’m now 10 years past menopause but it still has a big impact on my quality of life 🙁. I’m active, not overweight, stopped smoking 21 years ago, eat well, drink little, do yoga, walking and take magnesium (for PAF). Is there anything else I can do and is HRT still definitely out of the picture (as it seemed to be the only thing that worked for me)?
I went through menopause fairly young...I think it was 48 or 49. I sailed through menopause, with only insomnia as a symptom. So, I never looked into any replacement. I was very fortunate. But, I do worry I went through it too young.
@Brèagha I may have been more like 46 or 47. Compared to many of my friends who are well over 50, I was concerned, but maybe it is ok.
That's not too young. It's an average age. What's classes as early menopause is in 30s and younger.
50 is the average age for women to start menopause so you did not start it young.
@@jmk1962 when I think about it and look back it was 46. Had to do some math. I have friends that went as high as 50 or 52. So I beg to differ. I did start young.
Good info. Can you speak more on Bio-identical HRT in specific in another video? Thank you.
I have commented on BHRT if you want to check out my info on another question.
@@Zoe.TheBody360 ok great. Just trying to get as much helpful info as possible
Beautiful life . In the UK our Drs generally dont prescribe bio-identical hormones. We are given Body Identical hormones and neither are completely without possible risks and side effects. There are some private clinics that prescribe bio identical hormones but not many in the UK. However we do also have Drs who come from a variety of medical backgrounds who have set up private clinics in the UK which specialise in Body Identical Hormines. Consultations with them include full blood tests, scans etc and extensive follow up. They also prescribe testosterone specifically for women which is not readily available on the NHS if its indicated within the range of symptoms may continue to experience .
@@yasmindavidson5171 My apologies, it never occurred to me that you weren't in the states. Never-the-less, thanks for the info.
@@beautifullife8580 no apology necessary. I think I sometimes assume that most people who watch these uploads are also from the UK listening to a UK Dr, which is obviously not the case at all. I think maybe Dr Gupta is now just thanking God hes not a woman as he reads through his comments 😅
I had surgical menopause at age 45 and now at age 68 I’m still on it. I have great bones, muscle tone, healthy sex life and no metabolic issues. I do have autoimmune (lupus and arthritis). Can I continue HRT? I use estrogen, progesterone (for sleep) and testosterone.
It's been 2 years since this video. Dr Gupta, do you have any new insights or opinions regarding HRT? In this video you spoke about how HRT is not recommended if a patient has had breast cancer. About 70-80% of breast cancer patients have estrogen receptor positive cancer. That does not mean estrogen caused the breast cancer but estrogen possibly will feed the cancer and make it grow fast. How about patients who had estrogen receptor negative breast cancer? They should not be disallowed HRT. Because the risk of cancer recurring is lower than the risks of heart diseases, osteoporosis and Alzhemier's Disease due to menopause and estrogen being depleted from a woman's body. I have a friend who has been on anti-oestrogen medication after breast cancer and now she is having osteoporosis due to the medication. That is so tragic what medications can do to someone. She may not even have breast cancer again. And I am sure there are many other women like this. Women have had oestrogen their whole life and to be disallowed HRT is not right. Thanks Dr, hope this can be an idea for a new video or short. Much love.
Dr. Gupta. Based on your knowledge of Cardiology, what can you say about the claims that are made that Coronary Artery Disease (CAD) can be reversed partially or even completely by a strict plant Based Diet? Would you please comment on the viability of such a claim?? I have Two Stents in my heart and am a candidate for a possible third stent. I'd like to know if reversing this problem is possible for me or anyone else similar afflicted by CAD. Thank You !
What about TRT for men? 44 year old male here on TRT.
He did a video on that a few months ago
I advise men nutritionally with hormone deficiency. The problem with replacing testosterone is not a simple one as (a) it can be aromatised to oestrogen and in these circumstances can be dangerous for men and (b) you have to ensure you are not converting to much to DHT a more potent form of testosterone. I find that improving insulin sensitivity, losing weight improving nutritional health is the way forward and naturally raises testosterone. If you add a hormone, it is very important that you test for the metabolites and ensure you are detoxifying your hormones properly too.
Thank you
Great video! What about HRT for women who went through natural early menopause (early 40’s) and who have a family history of maternal heart disease, BUT...did not suffer from hot flashes etc or any other menopause symptoms.?
Hello Dr. Gupta,
Thank you for the information you provide to help us. I am a 56yr old woman who suffered a silent MI sometime in the last 2yrs. I have CVD along with triple vessel disease. I've had a TT from PTC and started menopause at 47. My current Doctor placed me on bio-identical HRT. And now I'm wondering if I'm in danger. I'm right side dominant with an 85% blockage. I've been on the Esselstyn no-oil diet and my cholesterol ldl is 130 my total is 200. Hdl is 150. I've been feeling really good with the hormones and look like my self again. I've only been on the HRT for 4mths. I seem to have plenty of blood flow considering.
Thank you in advance for any help
I have been on it for 3 years. I have osteoporosis, heart problems, and a dirty mammogram 😢
I really appreciate your videos, thank you for giving us the information we need. Other than HRT for meno, which I've been asked not to take. I take magnesium taurate daily but my PVCs have been crazy on days. What else can I do???
There is that flambouyant 1950's Raj Kapoor filmi shirt I like to see you wear.
Okay, now I watch video. 😊
Thank you 🙏🙏
Hi Sanjay, you are looking well! The interview you did with us is very popular in our group (Perimenopause Hell) and this one was posted recently. HRT is a controversial subject as you say, but it is kind of lodged in the minds of women that it is the only treatment for menopausal symptoms. Many women feel fobbed off when they are offered anti-depressants, so I am often explaining this is not a bad option, and worth trying, especially if low mood is also a symptom. Viz your comment about atrophy, the vaginal creams are actually very low in estrogen and I think the leaflets that come with them are very off-putting, they basically count these treatments as "HRT" when the dose is in no way comparable.
Personally I favour herbal methods, they are my choice, but we support many methods. One thing about the breast cancer statistics is that they were perhaps not as high as many might expect for the massive fuss that was made:
For
10,000 women WITHOUT HRT - 30 cases of BC
10,000 women taking HRT - 38 cases
I think for many women that is a risk worth taking, if your symptoms are severe and your livelihood is threatened. Women have to work longer and harder than ever now. If you are still paying a mortgage, losing your job because you are not coping is probably something you would like to avoid. Or if you are in the public eye, pouring with sweat from your awful hot flashes is very embarrassing.
One last thing to note - the type of HRT used in these studies was the older sort. It may well turn out that the modern bio-identical products are much healthier. There is no guarantee, but fingers crossed. In days gone by women had their menopause around 57, and often died by 59. We do need answers to maintaining Quality of Life for older women, as nature can be very cruel!
En France il est très difficile d obtenir une prescription d'hormones de synthèse. " THS" le corps médical reste persuadé que c est dangereux.
Dr Gupta , thank you for your insight and care. I’m a healthy 46yo women .Very recently I have had rapid heart rate, occasional BP if checked and have had recent acidity and anxiety . I also had a night sweat for the first time . My blood work has all coke back okay and the doctor is suggesting anxiety medicine. What should I do next ?
Very informative thanks. Love your shirt 😂
Good morning dr sanjay gupta sir will listen your video shortly thanks 29/11/2020
Had a hysterectomy 12 years ago, suffered horribly after a few years following it,rash,heart palpitations, anxiety, insomnia.. Ugh 😖😞😣, my doctor was always washing it away,
went to another doctor for a second opinion he said I was suffering from anxiety, doctors just don't seem to care about patients anymore!
Menosense maybe my last hope 🤷
So hot y go for hysterectomy
@@BlackMamba-lt8oe someone's bored this afternoon @stailleos...... do go away; come back when you've grown up.
@@BlackMamba-lt8oe if u only suffered menopause u would know!!!
@@akosw1977 😂😂😂😂 grown up, give u a baby as a gift
@@tnbn55 Thank u kindly ..I appreciate it immensely.
Love the shirt btw😎
Thankyou for the information Dr Gupta. I am going through perimenopause and was prescribed combined pill for heavy periods. After 3 years on it I came off it to see how things were and within 2 weeks I started with horrible ectopics that even kept me awake at night. I saw my Dr and had ECG and it was normal. After 5 weeks I concluded that the only thing I had changed was stopping the pill so I went back on it. Within 3 weeks the ectopics were hardly there. On 6 months and I tried to come off it again but same pattern happened. To me this suggests that not having the right level of oestrogen and progesterone must cause the ectopics not to mention the horrendous faint like flushes that happen when I'm not on it. I daren't come of it now unless I try going onto hrt which is oestrogen and progesterone but in a different format I think. Any information anyone has would be gratefully received. Thank you
Would Phytoestrogen not help with all that with out the cancer risk~?~? Much Safer~!
Don’t think I would have wanted to take the chance of taking HRT. I know many who took it and have breast cancer diagnosis now. I think there are more natural ways of reducing hot flashes; Exercise, stress management, maintaining a healthy weight and eating a healthy plant based diet. Love your videos, intellect and you’re hot!
sandramA heynemana and there are many who dont ! If I had been able to manage my hot flushes through alternative ways I would have done it. I tried everything...and I mean everything. Dr Louise Newson has a great website. If women are able to manage without HRT that's fine. If not also fine. People need to do their due diligence
@@yasmindavidson5171 I agree it’s up to each individual but too many unknowns down the road that can cause long term effects.
@@sassysandie2865 this is why its important for every woman to do her own due diligence. I was petrified of HRT. However. When I was recommended Dr Newson to look at her information I was shocked at how much inaccuracy and fear mongery is out there. Old reports and newer medications with no accurate reviews. I am not overweight and I follow a very healthy lifestyle. I do all of the things I'm supposed to try to do..... and still. I didn't escape the awful symptoms that go with perimenopause. In the UK I would say that Dr Newson is one of the most respected and well known menopause specialists. I cant speak for other countries or their health care provision. I just feel that your approach although well intentioned simply doesnt work for every woman. Its making a very complex and individual journey a one size fits all prescription. Diet, exercise and a healthy lifestyle are important at all ages for both genders. However they are also not a guarantee against any disease, or a good menopause experience.
@@yasmindavidson5171 are there any RC studies for long term effects that you are aware of?
@@sassysandie2865 RC?
Yes its really controversial. Im premenoposal and have symptoms yet so scared of HRT. Im 46 and very aches from most of my joints but still worried to take HRT. Any advice on nutrition that could help instead?