Ed Boyden: A light switch for neurons

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  • Опубліковано 16 тра 2011
  • www.ted.com Ed Boyden shows how, by inserting genes for light-sensitive proteins into brain cells, he can selectively activate or de-activate specific neurons with fiber-optic implants. With this unprecedented level of control, he's managed to cure mice of analogs of PTSD and certain forms of blindness. On the horizon: neural prosthetics. Session host Juan Enriquez leads a brief post-talk Q&A.
    TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes. Featured speakers have included Al Gore on climate change, Philippe Starck on design, Jill Bolte Taylor on observing her own stroke, Nicholas Negroponte on One Laptop per Child, Jane Goodall on chimpanzees, Bill Gates on malaria and mosquitoes, Pattie Maes on the "Sixth Sense" wearable tech, and "Lost" producer JJ Abrams on the allure of mystery. TED stands for Technology, Entertainment, Design, and TEDTalks cover these topics as well as science, business, development and the arts. Closed captions and translated subtitles in a variety of languages are now available on TED.com, at www.ted.com/translate.
  • Наука та технологія

КОМЕНТАРІ • 264

  • @liquidminds
    @liquidminds 13 років тому +10

    "That might change a couple things"... perfect closing :-)

  • @thisscreensucks
    @thisscreensucks 13 років тому +2

    lol the directors comment at the end of "that might change a couple things" might possibly be the biggest understatement ever uttered

  • @dark14cs
    @dark14cs 13 років тому +3

    This should be front page news , the implications of this research can not be understated. Bravo

  • @johntheactor
    @johntheactor 12 років тому +5

    I like how they mention the singularity in the last minute and a half of the talk like it's nothing.

  • @KhanRec0rdz
    @KhanRec0rdz 12 років тому +6

    Holy crap. My jaw dropped when he talked about the eyes! That's revolutionary!

  • @sunnyy3358
    @sunnyy3358 Рік тому

    Thank you so much for doing this TED Talk. The amount of scientific progress that could be done with these type of discoveries Ed Boyden is working on is amazing.

  • @aang7505
    @aang7505 5 років тому +1

    Absolutely amazing! Any updates?? 7 years later??

  • @feelingfeni4798
    @feelingfeni4798 4 роки тому +5

    5:20
    He said if we could some how GENETICALY MODIFY YOUR NEURONS IN YOUR BRAIN AND EVERY OTHER ORGAN to be a light switch to turn on or off and see what happens to you... Oh wait, he forgot to phrase it in a logistical manner! Oops

  • @VanKlaunch
    @VanKlaunch 13 років тому +3

    Absolutely enlightening and inspiring!

  • @Lifeintakes
    @Lifeintakes 13 років тому +1

    Great video, thanks TED!

  • @CheesemanXCV
    @CheesemanXCV 13 років тому +1

    Excellent research, excellent opportunities. Extreme need for caution and responsibility.

  • @oldmcgroin
    @oldmcgroin 11 років тому +12

    This man deserves more respect.

  • @P00P0STER0US
    @P00P0STER0US 13 років тому

    Juan was really poking the future with a stick there at the end. Imagine if one could download memories and upload them, either into the same person or another person.

  • @1a1a1and
    @1a1a1and 13 років тому +1

    This is sweeeeetttttttttt, loved the q&a ;)

  • @AntiProtonBoy
    @AntiProtonBoy 13 років тому

    That blind mouse thing was ace.

  • @joeymatee
    @joeymatee 11 років тому +4

    that was an amazing talk, i think without dry humour and silly pictures the audience was disappointed

  • @Uraffyouruse
    @Uraffyouruse 13 років тому

    Great talk

  • @kidmecha
    @kidmecha 13 років тому +5

    He is so calm about potentially controlling and/or changing our entire species. I hope he is an optimist (like me) and thinks that (once the technology is in use) we will all be mature enough as a people to use this technology for good and not evil.

    • @lovrosucic6780
      @lovrosucic6780 Рік тому +2

      Has your opinion changed in the last 11 years? (Still an optimist) Just curious :D

    • @deemanrt
      @deemanrt Рік тому +2

      @@lovrosucic6780 great reply! This is absolutely a control mechanism. Now if only they could find a way to deliver self-assembling nano-tech in a small delivery package that everyone has to accept. Then simply install the lights in key areas and start a pilot programming test. Perhaps they could use large black lights that appear as streetlights?
      Just speculating here, of course.

    • @aflamewithintheflame
      @aflamewithintheflame 9 місяців тому

      @@deemanrt haha .... phones are everywhere they would work. all the cameras and 5g ... this is like the matrix but we are walking around... or are we lol.

  • @niniomigrania
    @niniomigrania 13 років тому

    Sounds promising! Imagine very complex brain control with this, the possibilities are endless.

  • @brianvandenberg4467
    @brianvandenberg4467 5 років тому +5

    14:30 14:33 wow. How would you get FDA approval right???
    !for human subjects.....
    Claim “Defense Services”
    Claim “Classified”
    Surely folks wouldn’t do something like this in the Dark....

  • @nehorlavazapalka
    @nehorlavazapalka 13 років тому +1

    Am I the only one who sees the potencial of this becoming a torture device? I think that this will be one of it's first applications. It's much more easier to cause pain via this device than to substract memories from the brain.

  • @yaHARmeMATEY
    @yaHARmeMATEY 13 років тому

    TED when are u gonna do these in HD!

  • @libanlibanliban
    @libanlibanliban 13 років тому

    Truly amazing.

  • @kablamo9999
    @kablamo9999 13 років тому +1

    Incredibly interesting!

  • @JoeBrenan
    @JoeBrenan 13 років тому +3

    Just amazing, this is why i study and love science.

  • @Driux
    @Driux 13 років тому +1

    This talk deserves a standing ovation.

    • @aflamewithintheflame
      @aflamewithintheflame 9 місяців тому

      for being a complete psychopath yeah

    • @Driux
      @Driux 9 місяців тому

      @@aflamewithintheflameIgnoring this this is a 12yo comment of mine... That is such an odd thing to reply on two conceivable levels. You think he's a complete psycho for some undisclosed reason. You think he deserves standing ovation for being said complete psycho.

  • @13Septem13
    @13Septem13 13 років тому +1

    Hope one day I could use technology he talking about for example to learn stuff without reading books but just uploading it into the brain. It is so exciting!

  • @rpm297
    @rpm297 13 років тому +1

    I kinda saw the 'download information into the brain' question coming. But how would you or could you teach the human brain to translate binary code, if you could?
    Would it be more effective than one's own natural curiosity? Could the brain be stimulated in such a way it could send one's learning capacity into hyper-drive?
    Wouldn't that over-stimulate the neurons and render them into a kind of burnout?
    More questions than answers for me in this one... must have possibilities...

  • @1schwererziehbar1
    @1schwererziehbar1 13 років тому

    this guy has the most beautiful animations.

  • @stevenaudet
    @stevenaudet 13 років тому +2

    This is so scientifically awesome!

  • @ez910503
    @ez910503 13 років тому +1

    Fabulous. Absolutely fabulous. Perfect marriage of the physics and neurophysiology. Unbelievable.

  • @joshliu3964
    @joshliu3964 8 років тому +6

    This is still works in progress. Ed recently put up an AMA on Reddit. Hopefully psych meds will be a thing of the past

    • @rabia1180
      @rabia1180 8 років тому

      can you please link me to the reddit AMA? I looked but can't find it!

    • @joshliu3964
      @joshliu3964 8 років тому

      www.reddit.com/r/askscience/comments/4ak060/askscience_ama_series_im_ed_boyden_professor_of/

    • @rabia1180
      @rabia1180 8 років тому +1

      Josh L thank you Josh!

    • @jain355
      @jain355 7 років тому

      TThe Real ED Cure is ovеr 300 Yеars Old! twitter.com/a9c60516d47d92b7a/status/804602507225808896 Ed Bоydeеeen А light switch foor neurоns

    • @10bristol
      @10bristol 3 роки тому

      @@jain355 The twitter account is gone. Where can i find the information you talked about?

  • @SmushiSan
    @SmushiSan 10 років тому +1

    Are there any sources for the information he's saying? Can someone help me get his lab journal somewhere?

    • @NateSonnenfeld
      @NateSonnenfeld 7 років тому +1

      Just Google Ed Boyden, Karl Deisseroth, etc.Look up their names on Google Scholar, info's all out there.

    • @elyzavalerio52
      @elyzavalerio52 4 роки тому

      @@NateSonnenfeld ua-cam.com/video/Nb07TLkJ3Ww/v-deo.html

  • @MrBranboom
    @MrBranboom 13 років тому +2

    'That might change a couple things' XD

  • @9009tubeyou
    @9009tubeyou 13 років тому

    Interesting topic he have presented here. Imagine easy learning can be at schools if they had that kind of technology there.

  • @DeadWhiteButterflies
    @DeadWhiteButterflies 13 років тому +1

    Downloading memories. Bladerunner much? :D
    Great talk though.

  • @ChrisCapel
    @ChrisCapel 13 років тому

    @abram730 Oops, yeah I meant Parkinsons... Soooo yeah...

  • @test123ok
    @test123ok 13 років тому

    this is fantastic ! I can't wait till this becomes a real product.

  • @aang7505
    @aang7505 5 років тому

    Phenomenal!

  • @t3tsuyaguy1
    @t3tsuyaguy1 13 років тому

    @Ultra4 In it's simplest form, it's essentially a domino effect. One pair of sodium & potassium ions switch positions. This leads to a change reaction down the length of the neuron. Think of sports fans doing "the wave".
    Of course it's more complicated than that, but it's a common enough way of explaining the action of neural impulses.

  • @Phyrexious
    @Phyrexious 13 років тому

    Madness..?
    THIS IS... AWESOME!!!!

  • @TerielAtmano
    @TerielAtmano 13 років тому +1

    Wow. Now THAT are ideas worth spreading.

  • @epicbrowndragon
    @epicbrowndragon Рік тому

    Studied for 11 years…this then aired 11 years ago…and 11 years later what tech do we have using this?

  • @Volound
    @Volound 13 років тому

    @MrPlatonist they do, actually. understanding my position and my arguments is a prerequisite for being able to think about them. isnt that obvious?
    but if you mean it literally, then i didnt make any such accusation, so strawman.

  • @Redflowers9
    @Redflowers9 11 років тому +2

    Ed Boyden was a *prodigy actually, he worked for MIT as a teenager.

  • @nehorlavazapalka
    @nehorlavazapalka 13 років тому +2

    @hmspinaforethisisspa 100% sure that you are right.... but this can really become the worst torture ever

  • @LaBambathereal
    @LaBambathereal 13 років тому

    i have always wondered... how does our body make electrical impulses ? There's no power supply, or is there ? Do we make some kind of biotic electricity ?

  • @t3tsuyaguy1
    @t3tsuyaguy1 13 років тому

    Very clever.

  • @YourCritic
    @YourCritic 13 років тому

    Brilliant

  • @P00P0STER0US
    @P00P0STER0US 13 років тому

    @SheepRCool17 What need? We already have television, radio, cheap food, fatigue, and myriad other elements to keep us doing what we're expected to do. The idea of a physical implant used for that seems clunky. I think it's truly marvelous if such things can help people afflicted in such a way that this can help.

  • @SkiesAhoy
    @SkiesAhoy 13 років тому

    @andy3071190 Noise that you have to endure? Oh please. There's a very obvious mute button which you can use for those few seconds, if the starting music is really THAT aggravating.

  • @borderlinebuddhist
    @borderlinebuddhist 13 років тому

    i find it depressing that this isnt front page news.

  • @damoninsky
    @damoninsky 13 років тому

    @Icecoldpoker I think there should be science on every front-page. People need to pay attention and be more involved in its advancement. We should celebrate the incremental breakthroughs and build more confidence to lead us to bigger breakthroughs (such as vaccines, technologies, discoveries...not disappointments).

  • @Ko252
    @Ko252 13 років тому +4

    This is genius.

  • @ngarcia257
    @ngarcia257 13 років тому +1

    This is awesome... And this needs more views...

  • @Desert2GardenLV
    @Desert2GardenLV 13 років тому

    Someone please give this guy a Billion dollars. We need this.

  • @bryanm6080
    @bryanm6080 3 роки тому

    Anyone here in 2020 based off of Neuralink? Was looking at professors to start a masters in neuroengineering, came to search for Dr. Boyden @ MIT!!

  • @MrBalcora
    @MrBalcora 13 років тому +1

    If this research is successful, it will definitely change society

  • @ianmathwiz7
    @ianmathwiz7 11 років тому

    3:19 Migraines must be twice as common, seeing as they're listed twice :D

  • @tunnis7us
    @tunnis7us 13 років тому

    Finally good ted talk without stupid time consuming jokes in every sentence

  • @brianvandenberg4467
    @brianvandenberg4467 5 років тому +1

    13:28 14:37 14:40 part of my #ivXXX Protocol.....the Eye Tracking “Software” Portion.
    M EYE 👁 Algorithms that learn to activate switches with single commands (Private Internal Voice Vibration Protocol 2cd edition).
    Look at a switch/Relay and say “On”...Receiver activates!!!
    All this 3 second delay....with “Hey Alexa” or “Hey Siri” going obsolete in 5 years.....
    What channelRhodOpsin will you pick?

  • @Volound
    @Volound 13 років тому

    @saurabhdelft i disagree. i think that anyone i asked would realize my response addressed your argument and blew it out of the water. it shows you are just arguing from ignorance.
    and theres a certain kind of irony to someone accusing someone of being a "shallow thinker" who hasnt managed to grasp all of the rudiments of the english language, wouldnt you agree?
    but to answer your question, "what was the goal of black people, what was the purpose of black people in 1850 in the americas"?

  • @nightmathzombieethan
    @nightmathzombieethan 13 років тому +2

    Cool, AND scary.

  • @MrPlatonist
    @MrPlatonist 13 років тому

    @volound
    in that sense, yeah. but the way YOU said it, it seemed otherwise. iow, probably my mistake then. =)

  • @DeanOSupremo32
    @DeanOSupremo32 13 років тому +2

    Man so much good can come from this...but also evil

  • @Decimaster321
    @Decimaster321 13 років тому

    The evolutionary developments that lead to the growth of neurology must have been amazing, producing a system that seems so far removed from basic chemical survival. I wonder if we will find out how these cell systems emerged in my lifetime.

  • @t3tsuyaguy1
    @t3tsuyaguy1 13 років тому

    @belliebum12 LOL! Actually, they'll probably need programmers to write the interfacing software. You'll have plenty of work. ;)

  • @yaHARmeMATEY
    @yaHARmeMATEY 13 років тому

    @cristoretornebiblia then dont choose the HD options then :S

  • @FungusyHam
    @FungusyHam 13 років тому

    woah, I read this in scientific american a couple of months ago. Cool stuff!

  • @oicub2
    @oicub2 13 років тому

    @shade1978x 17:12 That does change things don't it ..

  • @vqly
    @vqly 13 років тому

    @Dixavd It's more than fine, every time that mouse get a jolt of blue light it's feeling a jolt of dopamine, the brain reward system.

  • @Rarae192
    @Rarae192 12 років тому

    @andy3071190 I love that noise: bwwwwoaaaaaONGGGGGG!!! It wouldn't be a TEDTalk without it.

  • @ErichoTTA
    @ErichoTTA 13 років тому

    I admit the name "Siemens" sounds funny.

  • @consciousnez
    @consciousnez 12 років тому +5

    I cant wait to genetically modify my children...i wasnt even gona have kids till i saw this. now i will have super kids

    • @jjk2one
      @jjk2one 6 років тому +1

      They will murder their parents.

    • @arie1899
      @arie1899 6 років тому +2

      Actually with no technology, they murder their parents...

    • @jjk2one
      @jjk2one 3 роки тому

      @@arie1899 Blade runner murdered his girl friend... figure it out if you can

  • @Volound
    @Volound 13 років тому

    @saurabhdelft this would be funny if it wasnt so sad.

  • @holdmybeer
    @holdmybeer 13 років тому

    kind of scary O.o but important also.

  • @Dixavd
    @Dixavd 13 років тому

    @vqly yes I know, I understand it perfectly and every way it works and the fact that the mouse gets pleasure from the blue light but just like irrational phobias I can't help but feel uncomfortable when I see it connected to that thing because of allt he times I have been in hospital in my life with drips and canulae and things so anything being connected to an alive awake subject - thanks for trying though.

  • @GiffyPooh
    @GiffyPooh 13 років тому

    Today I graduate with a Masters degree in Psychological Counseling... and I guess it's also the same day I change professions.

  • @andreeaweed
    @andreeaweed 12 років тому

    wow this is a great invention ...this is a genius

  • @Jotto999
    @Jotto999 13 років тому

    Neurology and genomics will transform humanity!

  • @roidroid
    @roidroid 13 років тому

    you could use this to insert new receptors types into your retinal cells, which will be sensitive to radiation sources that we can't naturally see. Such as various wavelengths of IR or UV. And the sky's the limit, we could enable until we have expanded our visual colour range 10x, 1000x, 100,000x, why stop?
    I want to see X-rays, RF signals, Neutron radiation, anti-proton streams.

  • @Redflowers9
    @Redflowers9 11 років тому +1

    It's great when child prodigies actually go on to be productive.

  • @matrixistrue
    @matrixistrue 13 років тому

    @Driux AMEN BROTHER

  • @ZeusLT
    @ZeusLT 13 років тому

    @saurabhdelft to serve us

  • @roidroid
    @roidroid 13 років тому

    @Th3CrimsnChin so deep

  • @roidroid
    @roidroid 13 років тому

    @P00P0STER0US It was kinda an embarasingly naieve question, "Oh so it's on and off, it's digital?".
    Juan reads too many sci-fi books, it's just another small development. It doesn't mean that in 5 years we'll all be uploading our memories, ffs what a jump Juan, these things take time and lots of further developments.

  • @charlesedwards5816
    @charlesedwards5816 3 роки тому

    nice

  • @Spencerianism
    @Spencerianism 13 років тому

    @maxgunn555 How old are you?

  • @SyllonRM
    @SyllonRM 13 років тому

    the guy talking is extremely nervous =D

  • @maxgunn555
    @maxgunn555 13 років тому

    @TheFounderUtopia how is it ironic i dont understand?

  • @Icecoldpoker
    @Icecoldpoker 13 років тому +1

    @ChalleFoV3
    This is not a breakthrough - This work in neurogenetics has been around for half a decade and consists of many many many smaller experiments. Slowly but surely a consensus backing an idea is formed...... it does NOT happen overnight.
    I am not being pessimisitic - Just being a scientist

  • @FrankFloresRGVZGM
    @FrankFloresRGVZGM 13 років тому +1

    Interesting, but frightening in the context of a for profit monetary system.

  • @kiddhitta
    @kiddhitta 13 років тому

    @borderlinebuddhist well then there would be no room for the new episode of Glee's advertisement

  • @ElementzUK
    @ElementzUK 13 років тому +1

    Reprogramming the brain. Wonderfully terrifying =)

  • @nicolareddwoodd7377
    @nicolareddwoodd7377 10 років тому

    I am so sorry, mouse.

    • @paulathebomb2
      @paulathebomb2 9 років тому

      Nicola Reddwoodd
      They are doing this with foster children, making them to forget thier families and where they came from to adopt them out for money. God help us.
      Reply ·

  • @user-iv8eb7xb8f
    @user-iv8eb7xb8f 4 роки тому +2

    It is pretty creepy actually.

  • @rlinfinity
    @rlinfinity 13 років тому

    @madzane94 Alga is singular. Algae is plural.

  • @maxgunn555
    @maxgunn555 13 років тому

    @TheFounderUtopia what makes his name ironic?

  • @Lostpanda123
    @Lostpanda123 13 років тому

    @juanarruti Thats true :D

  • @Volound
    @Volound 13 років тому

    "I regard the brain as a computer which will stop working when its components fail. There is no heaven or afterlife for broken down computers; that is a fairy story for people afraid of the dark,"
    - Stephen Hawking