T cell subtypes | Th1, Th2, Treg, Th17 | Cytotoxic T cells | exhausted T cells
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- Опубліковано 4 жов 2024
- This video talks about T cell subtypes | Th1, Th2, Treg, Th17 | Cytotoxic T cells | exhausted T cells
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0:01: T cell subtypes
1:10: T helper cells
4:20: T cell activation and differentiation
5:17: Th2 cells
5:53: Th17 cells
16:11: Cytotoxic vesicles lead to apoptosis
16:32: Activation of caspase 3 leads to apoptosis
17:40: Memory T cells play a role in immune response
21:05: Exhausted T cells are important for cancer
24:29: Negative core stimulation is a key mechanism to drive exhaustion
Q
Extremly useful video! It made many topics clearer for me! Thank you!
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
Hey!!!!!! Ur vedios are truly commendable
A small request, plz start a proper series for exams like csir net, ur content and way of explanation is amazing
It will surely reach heights.... Plz keep going!! 🌻
please check out my playlists (www.youtube.com/@animatedbiologywitharpan/playlists) already there is unit-wise content for CSIR NET. for example Unit13 is named as biotechniques, Unit 5 is dev bio... so on. Definitely take a look. These videos are better than any existing institutes. share with friends
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@@animatedbiologywitharpan thank you so much
Thanks for all the videos. It would be helpful if there would be a cursor/pointer during the presentation. This would simplify the understanding.
Thanks for your suggestion. We will incorporate this change in future videos
Very interesting 👌 thank you
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Very useful sir thank you
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Hey arpan sir can you plzzz make a video on interleukins in detail it will be very helpful Sirr plzz
OK thanks for the suggestion, are you a med student ?
very good video
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
Respected Sir, during Crohn's disease, the Pro-inflammatory cytokines should be more than Anti-inflammatory cytokines... Because the Treg cells are of less quantity than Th1 and Th17... but the seesaw is showing the opposite thing...
The seesaw is bit confusing. I thought pro-inflammatory cytokines has higher weightage hence the seesaw will dip that side. May be I should have used arrows to explain this. Any way thanks for all the feedback. Seriously it will help me to improvise
I wanna know that cytotoxic t cells are activated by infectious cell,Are their naive?😅
Sure I will make a video on cytotoxic t cells in details
Cytotoxic T cells also need to be activated by the APC to be functional because normal cell infected can`t give costimulatory signal please confirm once
yes cytotoxic T cells needs to be activated as well.
Is then th17 connected to autoimmune disease, th2 allergy response and th1 cancer ?
Is the prolonged th17 expression connected with th1 ?
Th17 is associated with auto immune disease and neurological disease like multiple sclerosis. also its role is important agains fungal infection. detailed video ua-cam.com/video/fcDvPJqiwH0/v-deo.htmlsi=F8Z8lb7ptkJJlC6P
multiple sclerosis ua-cam.com/video/Czchy27HEGQ/v-deo.htmlsi=J_DzzJlK_fzoJXiV
@@animatedbiologywitharpan Usually autoimmune diseases will lead to neurological diseases, am I wrong ?
Are autoimmune diseases associated just with the Mch 2 or mch1?
If Mch 1 Is triggered by Mch 2 that means that the epigenetic is leading the pathology. Am I wrong ?
@@animatedbiologywitharpan I have always been stuck on the dq2 (celiac disease). Could we say that Mch 2 is an Cd4 while Mch 1 is a Cd8 ? I know I am a pain in the ass
Yes @@il3mendo
Can u please provide a link for ur video. T cell activation. I really in need of it. Please bhai send me
ua-cam.com/video/R_9lNOByPpE/v-deo.htmlsi=QfjDcfL98Nc1OTlg
SIr at 9min 23 sec you say that IL4 activates TBET gene , shouldn't it activate GATA3 ?
yup, it was a mistake it is GATA3
I suggest you can refer to this article.www.sciencedirect.com/science/article/abs/pii/S1471490614000593
what if someone has too much memory t cells?
It generally does not happen. Technicaly there should be no problem
i saw a laboratory report from a patient where the central memory T4, T8 are too high and the effektor memory RA T4, T8 too low.