Cytokines and Chemokines

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  • Опубліковано 22 лис 2024

КОМЕНТАРІ • 82

  • @ahmednahian9123
    @ahmednahian9123 Місяць тому +7

    Used your videos in high school; used your videos in university; now using your videos in medical school. Thank you immensely!

  • @WanderTheNomad
    @WanderTheNomad 3 роки тому +31

    9:24
    (TGF-β) - Transforming growth factor beta

  • @sciencenerd7639
    @sciencenerd7639 3 роки тому +26

    Great stuff. In college I got to take an immunology class from the guy that discovered Interleukin 1 which was pretty cool.

  • @RishiYadav-vf7xh
    @RishiYadav-vf7xh 3 роки тому +15

    If you are a student and watching this,
    ''HE KNOWS A LOT ABOUT THE STUDENTS' PAIN
    PROFESSOR DAVE EXPLAINS''
    Watching before exams, surely deserves this channel. Thank you professor

  • @ebukahjoseph8016
    @ebukahjoseph8016 3 роки тому +5

    This was very timely for a paper I’m currently working on

  • @glennpearson9348
    @glennpearson9348 3 роки тому +12

    This series has been a heck of a journey, Dave. Looking forward to your insights on innate immunity! Thanks so much and have a glorious day.

  • @planetearth2249
    @planetearth2249 3 роки тому +63

    We all know how the saying goes:
    The more from Dave, the better the day.

  • @deajapon
    @deajapon 2 роки тому +8

    TGF-beta (9:25) should be transforming growth factor-beta, not tumor necrosis factor right?

    • @papongpapong1047
      @papongpapong1047 Рік тому

      I believe so-- I thought it was a typo to begin with, but when I heard him also say it in the script, I figured he must've meant it. I did some searching, thinking TGF was a synonym for TNF, but was still confused at the change of letter. Came to find what you had commented about, and wanted to add that TGF stimulates the production of extracellular matrix (ECM) fibroblasts, whereas TNF has anti-fibrotic activity.
      source: www.ncbi.nlm.nih.gov/pmc/articles/PMC8766837/#:~:text=TGF%2D%CE%B2%20can%20stimulate%20the,TGF%2D%CE%B2%20(86).

  • @DanielMacLir
    @DanielMacLir 2 роки тому +2

    Thank you so much for the explanation of the nomenclature.

  • @yifangli9298
    @yifangli9298 2 роки тому +1

    Thanks dave for providing information to my studies

  • @Krauvich
    @Krauvich 3 роки тому +65

    Good to know that not everybody on UA-cam is completely incompetent nowadays. Keep up the good work, Dave.

  • @drdrew7475
    @drdrew7475 3 роки тому +22

    Swipe, swipe, swipe, swipe... heheh funny, swipe, swipe, oh Professor Dave just posted! Finally something worth watching!

  • @manikantakolasani9531
    @manikantakolasani9531 11 місяців тому

    Dear Dave I enjoyed this video I would hear some explanation about the details of this classification of cytokines and their roles in detail through mentioning any articles as ur reference.
    Please share the details of the information you have mentioned in this video.
    Thank you 😊

  • @papariham4008
    @papariham4008 Рік тому +1

    THANK YOU SO MUCH DAVE EXPLAIN OH God INCREDIBLE EXPLAINING

  • @harshalambekar3724
    @harshalambekar3724 Рік тому +2

    Nice video sir you make microbiology easy 😊

  • @hv2314
    @hv2314 2 роки тому +18

    At marker 9:45, TGF-Beta should be "Transforming Growth Factor-Beta", not Tumor Necrosis Factor-Beta

    • @papongpapong1047
      @papongpapong1047 Рік тому +1

      I was also thinking this! Came to the comments to point it out. Thank you for pointing this out, too

  • @STICKMAN99100
    @STICKMAN99100 3 роки тому +3

    Oh my. you could write a textbook with this stuff.

  • @funkystyle7249
    @funkystyle7249 2 роки тому +1

    could you please put this in your immunology playlist?

  • @TheoTungsten
    @TheoTungsten 3 роки тому +12

    Preparing myself for university.

  • @Nxck2440
    @Nxck2440 3 місяці тому

    9:31 TGF is actually tumour growth factor, not necrosis factor :3

  • @meryamlazrak1329
    @meryamlazrak1329 2 роки тому +2

    Thank you sir

  • @CatFoxMusic
    @CatFoxMusic Рік тому +1

    At 9:35, TGF beta should stand for Transforming Growth Factor beta

    • @SeanElliottH
      @SeanElliottH 11 місяців тому

      I figured somebody else caught it 😉

  • @martinarenzi4744
    @martinarenzi4744 Рік тому +1

    Thank you Professor Dave! I love your videos, you are so clear and precise. Regarding this video, I found it hard to follow, I have the basic knowledge of chemistry, biochem, biology, microbiology, is there some basics one should study to fully understad and easily follow this video?
    Thank you as always for your work😃

  • @siddoo6778
    @siddoo6778 3 роки тому +3

    Great video! When a chemokines come in contact with a ligand, how does the cell know where to go? Does it have a gps of sort or does it roam on autopilot in a certain direction until it encounters another chemokines? Thanks!

    • @JG-lf6mk
      @JG-lf6mk 3 роки тому +3

      The cells utilise chemotaxis, which means they move towards the area where the concentration of chemokines is the highest. This happens because if you imagine the cell as a sphere with chemokine receptors uniformly spaced out all across it, the area that is facing the highest concentration of chemokines will have the most receptors activated. Therefore the cell will move according to this asymmetric activation of these receptors, moving towards the side that has the most receptors activated.

    • @iyedbouazdia3594
      @iyedbouazdia3594 Рік тому

      @@JG-lf6mk wow this so cool

  • @zhansayabauyrzhanova2492
    @zhansayabauyrzhanova2492 2 роки тому +1

    thanks very much!

  • @PIERRETMENDY
    @PIERRETMENDY 3 роки тому

    Thank you Dave

  • @femmiehh
    @femmiehh 2 роки тому

    Could you confirm if you meant to say 'Inflammatory bowel disease' instead of 'irritable bowel syndrome' at 7:58?

  • @zothanmawiitlangte9881
    @zothanmawiitlangte9881 9 місяців тому

    TGF is transforming growth factor not tumour necrosis factor

  • @Stop-and-listen
    @Stop-and-listen 3 роки тому +1

    Thanks!

  • @latauggeri131
    @latauggeri131 6 місяців тому

    In d last vid u said th17 Cytokine is named so as it's dominated by 1L-17 which is u said cxcL8 (cxcL8=1L-17)
    But here u r saying cxcL8 is = IL8.....
    Pls clarify

  • @liangcheng6778
    @liangcheng6778 2 роки тому +2

    you made a mistake. TGF-B is not tumor necrosis factor

  • @Lava-id3ee
    @Lava-id3ee Рік тому +1

    love you professor 😘

  • @shitalchordia1441
    @shitalchordia1441 3 роки тому

    Professor Jesus helped me again in my exam preparation

  • @asdf-th8jr
    @asdf-th8jr 3 роки тому +2

    make a video about lipid nanoparticles in covid vaccines

  • @arshithgowda8728
    @arshithgowda8728 2 роки тому +1

    Its advanced version beginners can't understand easily without proper basics of immunity

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  2 роки тому +2

      You have to start from the beginning of the immunology playlist.

    • @arshithgowda8728
      @arshithgowda8728 2 роки тому +1

      @@ProfessorDaveExplains thankyou sir 🙏🙏🙏🙏🙏

  • @Apoorva4102
    @Apoorva4102 3 роки тому +1

    why am i not able to watch the next videos in the series? :/

  • @ranaalmonyseer5426
    @ranaalmonyseer5426 3 роки тому +2

    GOOD

  • @drcaocuong
    @drcaocuong 9 місяців тому

    thanks to you !

  • @maitanphuc2006
    @maitanphuc2006 3 роки тому +1

    Thanks . 😍

  • @solomonaboagye9120
    @solomonaboagye9120 2 роки тому +1

    Looks like the TGF beta has to be tumor growth factor Beta.

  • @mujib4466
    @mujib4466 2 роки тому

    Thanks 🙏

  • @Afghan.Jalebi
    @Afghan.Jalebi 3 роки тому +2

    I didn't know Cr1TiKaL had a science based channel.

  • @jacobrose6490
    @jacobrose6490 3 роки тому +1

    Dude dave its summer time take a break big boy

  • @Zetsuke4
    @Zetsuke4 3 роки тому +1

    Nice

  • @A_Casual_NPC
    @A_Casual_NPC 3 роки тому +1

    Love your content, but way too high for this video rn. I'll be back later

  • @a_MhetOtw.4334
    @a_MhetOtw.4334 2 роки тому +2

    Ah big words! My brain is not available now!

  • @hangoo91
    @hangoo91 2 роки тому

    I couldn’t get the function from it 😅

  • @gnanasekhar2084
    @gnanasekhar2084 3 роки тому +2

    Can you tell how to do 73/4 divided by 62/5+8/3 plssss 🙏🙏🙏

  • @spoodlydoodler3552
    @spoodlydoodler3552 3 роки тому +1

    Why do I watch these...?

    • @drdrew7475
      @drdrew7475 3 роки тому +1

      Because knowledge is power. Hide it well

    • @sciencenerd7639
      @sciencenerd7639 3 роки тому +2

      Because it's pretty awesome

  • @CepheusMappy
    @CepheusMappy 3 роки тому +2

    Dave, are ghosts real? Just askin

  • @jalapenoandbanana
    @jalapenoandbanana 3 роки тому

    3:36
    I hope

  • @latinspeaker6659
    @latinspeaker6659 3 роки тому

    This is quite off-topic, but i have to ask.
    Let's say I have a rifle of an arbitrary caliber, with two wire-like extensions on the front.
    Is it somehow possible to shoot out a bullet, and electrify it using those extensions, without the bullet touching anything in the process?

  • @stolencbscontent3233
    @stolencbscontent3233 3 роки тому +1

    debunk gematria

  • @ruutharimaa
    @ruutharimaa 2 роки тому

    👍

  • @procrastinator5787
    @procrastinator5787 3 роки тому

    Earlyyy

  • @Cheesypizza2011
    @Cheesypizza2011 9 місяців тому

    booooo 👎