Halohydrin Formation
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- Опубліковано 21 сер 2024
- What's a halohydrin, how do we form them, and what do they do? Find out in this clip!
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Just amazing! I am from India, and there are thousands of tutors hungry for money, who will take a lot but don’t return anything. Whereas you have covered my whole chemistry Syllabus of organic chem of 12th grade on your channel! Your channel is best for a science stream beginner like me! Even my friends love it!
That's really good to hear about covering your syllabus! I'm just curious; how have your studies been going over the past few years?
@@PunmasterSTPअपना काम कर
@@blaze102 Sorry I'm not quite sure what you meant, as I'm only fluent in English and I wasn't sure about what google translate told me. Would you care to explain?
@@PunmasterSTP I just wanted to ask that the person you are asking about how he studies are going on in past few years in comment 4 month ago is not a well known personality
so why you are asking
@@blaze102 Ah, I think I see. I might also ask the question "why not?" A few people have replied to these types of comments, even after a decade, and I think it's been a neat experience for both me and them.
Back to the old style? No problem, I just love the lucid manner in which you explain things
just releasing 20 or so the old way to fill in some gaps!
THANK YOU FOR THIS
my professor's horrbile and I wouldnt even be surprised if his intention is to fail out as many students from ochem as he can. He covered this during the last 5 mins of class and i didnt get anything, so this really helped
I love these videos so much!! They are a true life saver!
Halohydrin? More like "Dave's videos for the win!"
THE OLD STYLE YAYAAYYAYAYAY
Your hairstyle is too good and videos also
Prof Dave! We literally just covered this today! How did you know I needed to watch your breakdown of it?
I know it's been years, but how'd the rest of your ochem class go?
@@PunmasterSTP Well I'm in 3rd yr of med school now so I guess it went alright haha.
@@ALdawg1994 Sounds good and I’m glad to hear it!
Man, wish these were up when I was in Organic I! XD
YAAY!! MORE ORGANIC CHEMZES!!!
Hi Dave , why halogen molecules are more reactive than the H atom (which should be more partial positive than halogen atom?)in H2O ? Why the double bond wont attack that H atom first ? As alkene are surrounded by H2O (final product should be formed as an alcohol?) , why halogen molecules still stand a chance to be attacked by the double bond ?
and sorry to bother u more , I want to also ask about Hydroboration , on step 2 : oxidation , what if it is a OH- attached to the Boron instead of the OOH- , then OH- will have nothing to kick out (originally OOH- will kick out OH- and replaced by R group to form - BOR ) , and the R group can't attach back to the Oxygen atom , then It would be Boron with 3 OH- , B(OH)3
1. can I just skip the H2O2 ( not adding any) and just add H2O & NaOH
2. is it OOH- must attack before OH- attack Boron? so can't form B(OH)3 directly? any chance OH- can attack before OOH- when OH- is just adjacent to the Boron atom?
Thank you so much so much if u can answer me all of this , Thank you for the new videos , I can see u r going to upload a lot of new organic chemistry videos in the upcoming days (the private unreleased videos list), Thank you so much.
don't worry, a hydroboration oxidation tutorial is coming!
a pi bond won't attack water, that would leave a carbocation and a hydroxide, not a likely mechanism. bromine insertion is thermodynamically preferable.don't forget that the kind of hydration you're talking about is acid-catalyzed and this is in CCl4 or a similar aprotic solvent.
delightful video
You are just awesome!! Wish you peace man
You are awesome, Prof. Just awesome. Thank you:)
Phenomenal. Thank you.
Good
Hi Dave, i'm little bit confused why Halogenation is an sn1 and Hydroxyhalogenation is an sn2, cause both gut the same Bromonium intermediate. Or is there a difference between hydroxyhalogenation and halohydrin Formation?
If you are referring to dihalogenation, I think that the second step is also sn2. Take a look at another of Dave's videos here:
ua-cam.com/video/_c84jxTo5bw/v-deo.html
As far as I can tell, "hydroxyhalogenation" means the same thing as "halohydrin formation".
Nice video! Would it be correct to say that water is acting as an acid in that last step of the last reaction?
when water attacks it's acting as a nucleophile, and in the proton transfer that isn't shown another water molecule acts as a base!
Dear Dave,
your lectures are nearly perfect.
But sometimes you write on the board while explaining your arrow-pushing.
While explaining arrow-pushing you are standing direct in front of your writings, so that one sees it first when you finished your drawings.
So it is difficult to comprehend your arrow-pushing.
For example in this video from 9:20 to 9:40 🙂
nice explanation
Plz explain halohydrogenation on alkynes!
Thanks man.... Awesome intro btw
love your videos👍
I like you a lot. You good
Professor dave please reply
In previous videos you told h20 is a weak nucleophile and can only do sn1 , but in this video how come h20 do sn2 ???
It can attack highly electrophilic species, like the intermediate here. And carbocations, etc.
@@ProfessorDaveExplains in last part you told that h20 is gona attack at more subsituted carbon, but in this case the both the carbons which is attached to bromine are evenly subsituted right? So h20 can attack either way?
Please reply
@@dobbysurfs Look carefully! There's a methyl group on one of the carbons!
H20 means weak reagent why not sn1
the bromonium intermediate is highly reactive
cheers
Wouldn't there be too much steric hindrance to do SN2 in the bromonium ion?
Didn't you say Sn2 can't happen on tertiary carbons? Also, since you say water solvent will always react first if it can, does that mean all Sn and E reactions have to be done in aprotic solvents if we don't want to introduce OH groups?
It is also important to consider that water is not a particularly good nucleophile. The water acted as a nucleophile in this case because the bromonium ion was very electrophilic. For example, this would not happen in an Sn2 reaction, since a carbon which is only partially positive is no where near as good of an electrophile
9:25 why would the methyl get pushed up?
because there is a bromo atom causing hindrance, so when water attacks, it does from the place where it finds less problems to approach. methyl changes cause that carbon was the only one that water could get.... and 2 things can not occupy same spot in space (in this case)
Why didn't the last one form an enantiomer too?
strange time for an upload!
How can Br forms 2 bonds apart from carrying a positive charge?
What do you mean by apart?
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Sir you look like rabir Kapoor in Bollywood
saurav jagtap *ranbir
Human Immunodeficiency Virus yes
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Chutiya intro