Claisen Condensation and Dieckmann Condensation
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- Опубліковано 8 жов 2018
- We've learned some enolate chemistry using ketones and aldehydes as substrates, so let's learn the Claisen Condensation, which uses an ester substrate, as well as the intramolecular version, called the Dieckmann Condensation.
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My professor NEVER said the OR's had to match when we were doing this in class. That kind of upsets me about that. This is actually very useful information. Thanks
Out of curiosity, how'd the rest of your class go?
My Professor didn't do a bad job at explaining this. In fact my organic chem 1 and 2 professor (same guy) was actually one of the best professors I've had. Professor Dave just has a way of explaining things though that just helps so much. Awesome vid!
this video is the best explanation I've had thus far of these reactions. a true life saver
Just one question dude, at what level are u studying ( college or school) this stuff????
@@vidit9024 college
@@vidit9024 A Jee aspirant huh?😂
I too thought the same thing
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@@vidit9024 Did you take the JEE, and if so, how'd it go?
@@paigezielinski8142 Out of curiosity, how'd the rest of your college career turn out?
This was an extremely helpful video on something that was giving me a lot of trouble! Thankyou for killing it again!!
Thank you very much, I'm a french student currently in biology studies and I had a big problem with understanding organic chemistry. Your explanations were very clear, I got it know ! Thank you again !
Hey how'd the rest of your organic chemistry studies go?
you are the best man ...keep it up !!!! thank you from Germany.
I’m from Puerto Rico and you are helping me A LOT. Thank you.
Very helpful during this pandemic, thank you soooooo much. You explain really well
Thank you Sir. My concept is finally clear for this reaction.
Thank you Professor Dave! This was really useful and now I understand it :)
THANK YOU PROF DAVE. I WISH I FOUND YOUR VIDEOS SOONER.
Thanks for this explanation! Im having an organic chem exam next week which also includes aldol and claisen condensations. And its nicely explained here so thanks
May i also request a video on the malonic ester synthesis? It would really fit into this catagory of reactions and would love to see a video on it :)
ok i'll put it on the list!
@@ProfessorDaveExplains Did that video ever get put up? that is what I am looking for now!
Hey I know it's been four years, but how did that exam go?
thank you!! you've helped me a lot, you and your explanations are the best
Thank you! This was so helpful. I'm taking my last class of the series during this pandemic......
Oh wow; I hope it went well!
dave mate you really are a gentleman and a scholar!
Going to be honest here. Even though I left the video at exactly where I needed to start it, I started over for the jingle.
I think a lot of people actually do that, myself included sometimes.
Thanks for helping!
My finals started and I've got organic chemistry next Sunday so this is very useful ~
I know it's been a year, but if I might ask, how'd your ochem final go?
Hello professor dave thank you for the explanation
4:59 won't there be acid assisted ester hydrolysis due to addition of acid HA at the last step/
You are a wonderful man. Long live Dave
This feels like learning in LKG class... Very interesting and very informative❤😍
"feel free to e-mail me" as if the guy hasn't done enough
Thank you Sir
Thank you!
Hi professor, will the Dieckmann Condensation product be attacked by the alkoxide again and we need to undergo acidic workup?
At the very end of the video, the dieckman condensation product has an alpha carbon, so could it be deprotonated and continue the reaction?
Ur great specially in physics
Thank you so much Dave! It´s a shame your amazing videos do just get that few views. Greetings from Germany and thanks for making o-chem fun! :)
Gran video!!! 😊😊😊😊
what if you are starting with eto- then adding NaoCH3 Rs not matching
Thank God for you even after 5 years
What if you use a different base to remove an alpha proton? Can you use NaOH or would the ester be prone to base-catalyzed hydrolysis? What about sodium hydride or amide (NaNH2)? I'm assuming NaNH2 would create an amide but not sure about NaH.
been trying to view this video for a few days. doesnt seem to work
Wow, I love thissss
What is the difference between Claisen and Alden condensation and which is more optimal in reactions of functional groups?
claisen is ester substrate, aldol is aldehyde/ketone substrate
4:40 Wouldnt part of the intermediate react into an alcohol, rather than the desired product? If the charge is on the oxygen, it would also be protonated, wouldnt it? If this is true, how can you isolate the final product and if this is false, why doesnt this happen?
Claisen Condensation Vs Claisen Reaction and Claisen Rearrangement : ua-cam.com/video/AZy5NgeTPpg/v-deo.html
Why here alkoxide is used for proton abstraction and not the regular strong base as in the case of aldol condensation?
Alkoxides are strong bases.
Sir is the carbon in methane a primary secondary or tertiary ?
none!
Thanks .
You’re the best
very helpful dave iam from india
Very helpful for JEE! Thankyou.
Claisen Condensation Vs Claisen Reaction and Claisen Rearrangement : ua-cam.com/video/AZy5NgeTPpg/v-deo.html
How'd the JEE go?
Good
Dieckmann? More like "Dang good information man!" 👍
Still saving students around the world in 2024, thanks Dave!
Beta keto ester * 4:53
Prof, do you have tutorials on glycolysis?
Prof Dave, please I'm waiting for a reply?
Wow you are an impatient fellow! Yes I do, check my biochemistry playlist.
@@ProfessorDaveExplains Thank you Prof Dave, I believe with your help I will get an A in biochemistry this semester.
@@danielagyemang5858 I know it's been a few years, but if I might ask, did you indeed get that A in biochemistry?
@@PunmasterSTP No. I got a B
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It's about 00:30, but whatever, I'm early 😅
Yes professor dave explains .
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my ochem professor could never
I know it's been a few years, but how'd the rest of ochem go?
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Finally
I just saw your comment and I'll give you a reply as well. How you doing today?
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It can definitely be tough! If I might ask, how have your studies been going?