Stemming vision loss with stem cells: Dennis Clegg at TEDxUCSB

Dr. Clegg earned his BS degree in biochemistry at UC Davis and his PhD in biochemistry at UC Berkeley, where he used emerging methods in recombinant DNA to study the sensory transduction systems of bacteria. As a Jane Coffin Childs Postdoctoral Scholar at UCSF, he studied neural development and regeneration. He has continued this avenue of research since joining the UCSB faculty, with a current emphasis in stem cell research. Dr. Clegg is the recipient of the UCSB Distinguished Teaching Award in the Physical Sciences, and served as Chair of the Department of Molecular, Cellular and Developmental Biology from 2004-2009. He is a member of the UCSB Neuroscience Research Institute and Co-Director of the UCSB Center for Stem Cell Biology and Engineering. He is a Co-Principal Investigator of The California Project to Cure Blindness, a multi-disciplinary effort to develop a stem cell therapy for Age-Related Macular Degeneration.
In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)

[@seekeroftruth1200]

I'd love to hear an update now 5 years later. How is this technology progressing?

[@sandraabrams7717]

Has there been more research addressing cataracts and does it work If so, is it available now?

[@4PRK]

Any update 10 years later? Over 35 years ago, I was trained at Stanford and did research at UCLA - Jules Stein Eye Institute where I implanted red blood cells in the subretinal space adjacent to the retinal pigment epithelium. I could have easily implanted stem cells in this animal model. With the regulatory environment and theoretical safety considerations, it was not possible to proceed with human trials. I would think that others have done so more recently? Any updates? Any success?

[@vickymoloi6311]

Can this therapy help my sister.?She went blind at the age of 35 due to CMV destroying her retina on both eyes.

[@kubikinterior7360]

when will start treatment for vision loss for AMD we are waiting for long long years but don't know when we can see world

[@lucyvallejo2243]

I need help to help my son he is blind in one eye and blurry in the other eye from diabethic rethnapathy please help me thank you

[@0x_33]

Can I get more info to understand his situation.

[@Prabhatyadav111]

Is it possible to recover optic nerve damage

[@alexiusdante]

very interesting..

[@Rene-uz3eb]

If hypoxia is the main problem then stem cell replacements won’t work for macular degeneration
“Ischemia and hypoxia have been implicated in the pathophysiology of age related macular degeneration (AMD)”
Metabolic physiology in age related macular degeneration, 2011

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