Regrowing heart muscle with stem cells | Dr. Chuck Murry | TEDxSeattle

Heart disease is the number one killer in the world, but researchers are evolving a new branch of medicine to tackle the issue. For over 20 years, Dr. Chuck Murry has studied the causes of cardiovascular disease and researched harnessing the potential of stem cells to repair damaged heart muscle. In this talk, he shares his journey and groundbreaking research, providing hope through evidence that we can heal the heart. Dr. Chuck Murry is a physician-scientist at the University of Washington, where he founded and currently directs the Institute for Stem Cell and Regenerative Medicine. Heart failure-now the number one cause of death worldwide-is the motivation behind Murry's specialized research into innovative treatments. Murry believes that it is not enough simply to help a patient, plagued with chronic disease survive. Instead, his pioneering work seeks to harness the potential of human stem cells to eliminate the disease from the body. While Murry feels that, even after his 31 years in the field, there is still a great deal of work to accomplish, achieving this vision is definitively much closer today This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

[@mohammedmoin7180]

They are the hope of future heart patients may god give them success

[@isaiahslucher7400]

I’m going to try Stem Cell Therapy to reverse my Heart Failure

[@abs_abs6199]

I was listening to the podcast but it urged me to see the video...

[@May-gw4xx]

Me too!

[@jondebruyn8988]

Me too haha

[@toxichammertoe8696]

We need an update from the trials at university of Washington

[@richarddickson6559]

Thanks Dr Murry, I am down to 26% post MI. You have given me huge hope. I need to last long enough for it to be approved! Hope it reaches international trials soon!

[@Liberty309]

Good healthy diet and moderate exercise will get you there.

[@richarddickson6559]

@@Liberty309 the heart doesn’t regrow. Regardless of exercise or diet, once damaged it’s permanent.

[@Liberty309]

@@richarddickson6559 Yes I realize that. My suggestion is to help prevent another m.i. You should look into intermittent fasting as well. Check out Dr. Eric Berg.

[@ireolaaa]

This came just in time, this happen to be my term paper topic I am presenting tomorrow. Great discovery to the team 🎉❤

[@j.rogercavanaugh3971]

My wife is the picture of health. No high cholesterol, no high blood pressure. In 2011, she was 55, we had a snow fall and spent many hours shoveling snow. She had excruciating pain in her chest. We thought she was just sick. We went to the doctor 2 days later and they did an EKG and said she was having a heart attack. She was transported to a hospital where she eventually recovered, but a part of her heart had died. The crazy thing is she feels normal. No shortness of breath or weakness. Her cardiologist said he only had 3 other patients that this has occurred in. Would she be a candidate for stem cell therapy to regenerate the part of her heart that was injured and “died”?

[@lucario2188]

When a heart attack happens some part of the heart always dies.

[@toxichammertoe8696]

@@lucario2188 dude I didn't know that that!😲

[@lucario2188]

@@toxichammertoe8696 Yes, then it scars, scientist are researching ways to enable the heart to heal himself and at least reduce the size of tissue that dies. Currently there are two approches in this research one is stem cells and the other is drugs. Some scientists are studying Zebra fish to see if it possible to replicate their ability to regenarate their heart, they have discovered a molecule responsible for healing in zebrafish, but there is so much more left to do, they aren't even in animal trials. Also the drug approach is pretty much only going to work if you take it after the heart attack, like if you had a heart attack three years ago and you take it now it's not going to work on you.

[@BT-km7nl]

Stem cell therapy is kinda joke. We are like at least century away for this

[@lucario2188]

@@BT-km7nl if you are refering to being able to cure heart failure just by using stem cell treatment i would say we are decades, not centuries, most cardiologist agree on this, but treatments that reduce complications aren't that far from being a reality.

[@femmefatalexX1]

Condolences to your mother sr

[@adobo_harl2278]

Hopefully they focus more on the source of the problem which is the Food industry.

[@madisoncaswell1864]

source?

[@MrsJakas]

​@@madisoncaswell1864 hahahahahaha!

[@analogaudiorules1724]

Thanks for making this affordible and not cost an arm and a leg...

[@SkipYearSix]

Please look into regeneration health for dry eye disease or meibomian glands.

[@michaeloneill6134]

I am amazed and pleased at what the doctor has achieved. I have one problem without a simple solution. I hope that one day in the not too distant future research of this kind will not rely on the use of animals in experiments. In this case it appears to be justified but millions of animals are subjected to experiments every year and many of those experiments are not worth the suffering that they cause. It is very easy for a researcher to get a grant and start doing unthinkable thinks to animals that live their whole lives in small cages.

[@karenvtechgal397]

Animals for research is worth it but for food that's what is the problem ban animals for food, as there's no need you can eat non-animals for food

[@zikirnafas2221]

Lets test on jinniss and devils instead to help humans survive to do more good beneficial works

[@aminagrini3151]

i wonder how much that would costs

[@archangelspardathadon1982]

I want to be apart of this trial

[@jacobsolliday8017]

What is the standing of this now? Can a person get this therapy?

[@j.rogercavanaugh3971]

Currently, Her heart is operating at only 25 % according to the cardiologist. So he implanted a defibulator. But she feels normal still!

[@toxichammertoe8696]

Ask her to be a volunteer for the trials at the University of Washington

[@keving690]

Does anyone have a link to recent advances?

[@madisoncaswell1864]

search for CONCERT-HF study

[@nourasdeen8781]

Hi Dr. Chuck, in 2018 I had two stents and I will be able get treated stem cell exosomes. I am in NewYork. If you advise me something then I will come cover to Washington and It will be my privilege to meet you. please inform me.

[@saman21590]

U are god himself doc.. humanity loves you

[@thedykewitch]

god himself??? he murdered dozens of monkeys in sick experiments

[@rickyholbrook]

Please post new information....my heart is in bad shape

[@jediknight73]

I'm 47 I am try to be healthy life. And hope i live long enough to see life span of 150!

[@abs_abs6199]

*DOPE*

[@chesterwoodring5228]

6:35 another trick up sleeve. adding genetic material from jellyfish. Make it becomes bioluminescant. another name for that process is called Luciferace Luciterase

[@aestheticmusic2635]

Is their any minimum requirement of ejection fraction, my father has an ejection fraction of 25%. Please someone answer.

[@walterinsuasti9432]

An ejection fraction below 50% is considered abnormal, but some patients do really well with an ejection fraction below this number. These patients usually need to be treated with medication that will allow them to have a good quality of life. I suggest you see a cardiologist, so he will recommend the best therapy for yor father. Best of luck 🤞

[@aestheticmusic2635]

Actually my father have an icd implanted since 7 years , I wanted to know will this stem cell therapy will be done on patients with just 25% ejection fraction ( which is very low)

[@kevinmyers1789]

I am 66 years old. I had a heart attack. My last ultra sound showed my EF at 14%. I am still working but have slowed ay down

[@toxichammertoe8696]

Stem cells is the key to rejuvenate the body

[@bhargavchaudhari9971]

Very less view unbelievable

[@harshinigangapuram9116]

I just hate the sound quality of the video

[@richardposna3223]

what else do you Hate ?

[@stapark11]

cool

[@jadelindholm2759]

I had heart failure. How could I registerfor a human rrial?

[@madisoncaswell1864]

there have been human studies done, search for CONCERT-HF, not sure if theres any new studies being done.

[@mess6654]

Who else heard the Simpsons theme song

[@Rene-uz3eb]

2:16 btw I would speculate, that because we know that injecting your own msc stem cells into the heart muscle replaces scar tissue with new heart muscle, this is actually the normal path of heart repair. Ie if in younger patients still with good healing capacity, which geriatrics clearly lack, they would be observed over time after a heart attack, one would find that their scar tissue actually also gets replaced by new muscle tissue. Ie the scar tissue is just a logical scaffold to stabilize the heart first. Otherwise, how do the injected stem cells even know that this scar tissue should be replaced?
3:50 this is incorrect. The cells that build the scar tissue after a heart attack are heart stem cells. So the heart does have stem cells. Also stem cells can move.
12:46 the problem seems to be (ventricular tachycardia) that you only replaced the heart muscle, not the conducting fibers that permeate the muscle and synchronize the beat.
So your human trials may not work as well because you are treating geriatrics who have more toxic tissues than the animals in the studies, that is they won’t grow back said conducting fibers on their own because stem cells and progenitor cells are very sensitive to/don’t work in even slightly toxic/hypoxic environments

[@ultimatespider-man6405]

i don't know the ethical
can we plant it inside the patient himself from the beginning by that can they o together

[@cpt.cornelius723]

Those poor animals.

[@Theodora555]

You may or may not be aware of the facts. Animals arent the only species used as experiments and animals were not the first! God bless and Amen.