Can CRISPRa solve aging?

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  • Опубліковано 11 вер 2024

КОМЕНТАРІ • 41

  • @TheSheekeyScienceShow
    @TheSheekeyScienceShow  2 роки тому +9

    CRISPRa + ME = ESish

    • @randenrichards5461
      @randenrichards5461 2 роки тому +1

      Scratch the sense of humor lol. Yes your sense of humor is a bit corny, but we are here for your brains anyway. Thank you for all you do.

  • @ezekielsbot
    @ezekielsbot 2 роки тому +12

    You’re awesome. Thank you for always believing in your intuition. It’s refreshing listening to people who actually know what they’re talking about!

  • @machinized
    @machinized 2 роки тому +18

    I want to drop everything and study genetics, that is so damn fascinating, thanks for another great video!

  • @user-mm8jv3tn2l
    @user-mm8jv3tn2l 2 роки тому +4

    Definitely want a sense of humor whenever I experience cellular reprogramming. I love your videos and look forward to your interviews as well! Please keep up the great work.

  • @ioanmariandanila3452
    @ioanmariandanila3452 2 роки тому +7

    Reprogramming can produce stem cells or rejuvenated cells, at best. Some scientists believe that reprogramming cannot rejuvenate cells without making them first stem cells, without complete dedifferentiation. Stem cells maybe enhance regeneration. There is a stem cell theory of aging. Rejuvenated cells enhance organismal rejuvenation, at best, because they wouldn't change the old ratio of the cells. There is also a mutation theory of aging. Reprogramming cannot repair mutations, but CRISPR can... Maybe it is clear how could CRISPRa solve aging. And even if it cannot solve aging, it could extend lifespan, provided that it is safe.

    • @jefflittle8913
      @jefflittle8913 2 роки тому +1

      "Reprogramming cannot repair mutations, but CRISPR can..."
      If CRISPR solves aging it will be because it promotes longevity - not because it reverses mutation, which could be a near-infinitely hard problem. If you have mutations, then you just have to be happy with the fact that someone slightly different than you is what lives on...

  • @themacso4157
    @themacso4157 2 роки тому +2

    Aaaaaaaaaaaaa i love U I LOVE U I LOVE U. THANKS! Please upload anything u can about crispr gene reprogramming😊😊😊😊😊 THIS IS THE FUTURE, THIS WILL BECOME REALITY

  • @georgbrindlinger1008
    @georgbrindlinger1008 2 роки тому +2

    Luv your sense of humor sheeky... made me giggle... thanks for all your great vids..

  • @JR-ht2vy
    @JR-ht2vy 2 роки тому

    Always a pleasure to listen to you and always interesting. Keep us informed on these type of heath/life extending videos. I always enjoy your mice 🐭!

  • @JZGreengo
    @JZGreengo 2 роки тому +1

    I’m in so much physical pain, each day I want to die from my condition, I wonder if this could just fix my messed up nerves, I’d totally donate my body to research on this instead of having my sexuality and brain demolished by pharmaceutical drugs to treat my condition. I take nothing for my condition now and I hope I can participate in clinical trials one day for something like this, I’d rather die fighting than die doing absolutely nothing. I’m 22, not a 90 year old, I hope this seriously can not just reverse age but restore damaged bodies and autoimmune diseases.
    I sound like a crazy person, I’m just in pain, desperate af and researching things to find hope in daily and I feel like if we restore aging we also restore the bodies normal functionality, who wants to live be old and young at the same time but still have the effects of back pain and cramping fingers that come from aging

    • @kenw1849
      @kenw1849 Рік тому

      Is there a name for your condition?

  • @ArticBlueFox96
    @ArticBlueFox96 2 роки тому +3

    This is amazing.

  • @michaelvaughan2888
    @michaelvaughan2888 2 роки тому +1

    whats your thoughts on intravenous sheep placenta. since sheep placenta is swimming around in hormones which make embryonic stem cells. do you think it can be transferred?
    pls let me know if you make a video on it

  • @thewisegirl6459
    @thewisegirl6459 2 роки тому

    lol at The Grinch reference 03:55

  • @edwins2595
    @edwins2595 2 роки тому

    We are indeed separated by a common language.

  • @whatthefunction9140
    @whatthefunction9140 2 роки тому +2

    Just noticed that the drawing of your hair is a helix.

  • @yanshen1795
    @yanshen1795 2 роки тому

    Is there anyone working on this with correcting Parkinson's disease? I would be very interested in that ... Michael

  • @aby110
    @aby110 2 роки тому

    Isn't it just CRISPR-CAS9 that has demonstrated the ability to cause DSB and off target mutations ?

  • @ioanmariandanila3452
    @ioanmariandanila3452 2 роки тому

    Can, in principle, CRISPRa cellular reprogramming turn into induced pluripotential stem cells important neurons from memory neuronal networks?

  • @Azmarith
    @Azmarith 2 роки тому +1

    You don't hate to say "I told you so" at all XD

  • @alecpokrandt3322
    @alecpokrandt3322 2 роки тому

    Are you active on twitter?

  • @OurBengals
    @OurBengals 2 роки тому

    Diagnose for aging. Wish i could do that for a living.

    • @kenw1849
      @kenw1849 Рік тому

      What? Diagnose what? You mean like a Geriatrician?

  • @gregorysagegreene
    @gregorysagegreene 2 роки тому

    You're talking about giving an entire waterworld nano-planet the skeleton key to terraform itself. Not sure we understand enough yet. Zombie apocalypse might be mildest outcome.

  • @AceKinG2024
    @AceKinG2024 2 роки тому

    I do that every month. I Dry Fast for 3 days and feast on protein.

    • @BR-hi6yt
      @BR-hi6yt 2 роки тому

      But them mTOR activation will age you

  • @MapleWorld
    @MapleWorld 2 роки тому

    I'd like to thank myself for liking this video. I am pretty awesome. Go me!

  • @EpicGir1
    @EpicGir1 2 роки тому +1

    ATTENTION longevity fans: Vote for Lifespan Extension Advocacy Foundation during this years Project for Awesome (you have 22 hours left)

  • @chrisj5505
    @chrisj5505 2 роки тому

    Lunatics and genetic modification. I hope it backfires miserably

  • @HassanWorld
    @HassanWorld 2 роки тому

    This is amazing. Would love to have you on my channel.😇💯

  • @GM4ThePeople
    @GM4ThePeople 2 роки тому

    Cheekey, Sheekey, & top work on a most exciting & transformational topic! Kindly consider reproducing, for the common weal. One lass can only do so much. And perhaps spamming embryos + embryo sequencing & selection = superbabies is the surer way to a brighter future for our folks & fams: all this crispier Yarma-narka malarkey all gets a little complicated, don't it? C'mon, man! Regards, G.M. o/

  • @alecpokrandt3322
    @alecpokrandt3322 2 роки тому

    Do you invest in CRISPR stocks?

  • @tableanalyz7724
    @tableanalyz7724 2 роки тому

    How about curing tinnitus? You can live to be 1000 but you'll want it to end early if your ears are screamming

    • @officedepot31
      @officedepot31 2 роки тому

      Block out tinnitus with your mind. Started when I was 12 and it was so loud i could not sleep. 46 now and it came down to training my brain to ignore the noise. Takes time and patience. I would love a cure though along with hear loss rejuvination.

    • @tableanalyz7724
      @tableanalyz7724 2 роки тому +2

      @@officedepot31 Not that simple friend. There's mild tinnitus and SCREAMING tinnitus and a lot in between. It's not a binary state condition

  • @anoniem9518
    @anoniem9518 2 роки тому

    ... and now in human language :)

    • @OurBengals
      @OurBengals 2 роки тому

      simple yes or no woulda been good for me

    • @BR-hi6yt
      @BR-hi6yt 2 роки тому

      She needs to say at the BEGINNING if CRISPRa + ME is BETTER than plain old CRISPR, how much, still dodgy or what? etc - rather than the history of genetics with big words included. I haven't time to listen to digressions sadly. Not a student or want to be.

  • @cybermac441
    @cybermac441 2 роки тому

    Could you please not use cursive? We cannot understand your writing.