I don't know how many hours now that I have been trying to understand serine protease and how they work. Come across this video and get it instantly! Thank you so much!
+Veezenn Glad you´ve found us! In his advanced biochemistry course (www.lecturio.com/medical-courses/biochemistry-advanced.course) you will find even more detailed explanations. Take a look ;)
Hi :) Prof. Ahern doesn't use UA-cam but he will be happy to answer your question at www.lecturio.com/medical-courses/biochemistry.course You need to register first and then will also have access to hundreds of other free medical videos.
Thank you so much! I am studying for biochemistry exam and presentation that we used in lecture is terrible! In this video ı understand this mechanism perfectly! Thank you!
Thank you for your comment, do not hesitate to start your free trial as Lecturio could become your best study-buddy. Watch the complete course on lectur.io/serineprotease and figure it out by yourself :)
Thank you for your comment! If you enjoyed the video, don't forget to subscribe and turn on notifications to stay updated with all our UA-cam videos. 🤗 Additionally, for more learning opportunities, we invite you to sign up here and explore even more of our free content, along with all the study features that can help you ace your exams: lectur.io/freecontentyt
So what's released is a NH2-R and COOH-R with the enzyme acting as catalyst, here it is seen that amine and an acid is released, this shows that serine protease releases acids and amines, so is the protease inhibitors targeted to supress the release of excess acids and amines, (in this case of the serine protease) of course there are other proteases but an analogy can be assumed
feels the mechanism for the last step of Ser to form the -OH group and release of carboxylic acid not correct. The tetrahedral intermedia, the central carbon formed five bonds, is that a mistake?
Hi! I followed this to a T, thank you so much for explaining it in such depth. I do however have one question. Around 9:10, right when the NH2R gets released, and the remaining portion of the peptide covalently bonds to Serine, there seems to be a missing CH2 on the serine side-chain. I could be wrong, but that's the only part I am not following. Thank you again!
Hey! Thanks for checking us out. Our lecturers do not use UA-cam but they will be happy to answer your question at www.lecturio.com/medical-courses/amino-acid-metabolism.course. You need to register first and then will also have access to hundreds of other free medical videos.
Thanks so much for your support!! We're happy you're enjoying the courses. Also feel free to create a free account at www.lecturio.com to get more free video courses.
that was an awesome explanation. tysm. sir in 2 nd stem how come the carbon had double bond even after forming tetrahedral confirmation with oh here instead of nh in first step where it was a single bond.
+yash parikh Hello Yash, thx for your kind comment. As I am only the UA-cam manager at Lecturio Medical Education Videos, this detailed question is a bit to difficult for me to answer. But did you know that we also have an elearning plattform for medical education where you can watch even more free lectures and ask questions to the professors. Try for free at www.lecturio.com/medical-courses Thanks again!
+Giselle Diazzi Hey Giselle, you are welcome! Thx for oyur nice comment and feel free to watch even more free lectures on www.lecturio.com Thanks again!
I've spent hours reading trying to understand enzyme mechanisms. This video made this so clear to me. Thank you so much!
Best lecture I can find on Serine Protease! Thank you!
Wow could not be more clear! Thank you, this really prepared me for my biochemistry exam!
I don't know how many hours now that I have been trying to understand serine protease and how they work. Come across this video and get it instantly! Thank you so much!
This explanation is so crisp and descriptive, it helped me fully understand every step really well :) Thanks!
This guy is such a good teacher. Wow
I've searched for this a long time. Thank you!! :)
+Veezenn Glad you´ve found us! In his advanced biochemistry course (www.lecturio.com/medical-courses/biochemistry-advanced.course) you will find even more detailed explanations. Take a look ;)
This explanation was EXCELLENT! Two thumbs up 👍👍.
Kevin Ahern sir ?!?!? I really love the way explains biochemistry concepts !! :D :D :D Amazing professor ! :D
Hi :) Prof. Ahern doesn't use UA-cam but he will be happy to answer your question at www.lecturio.com/medical-courses/biochemistry.course
You need to register first and then will also have access to hundreds of other free medical videos.
Perfectly explained. Thank you!
Thank you so much! I am studying for biochemistry exam and presentation that we used in lecture is terrible! In this video ı understand this mechanism perfectly! Thank you!
Thank you for your comment, do not hesitate to start your free trial as Lecturio could become your best study-buddy. Watch the complete course on lectur.io/serineprotease and figure it out by yourself :)
Thanks a lot, it's a marvelous explanation
This was one of the best explanations I've ever had :')
Very clear explanation! Thank-you for your help!
+Jessica Bednark We have to thank you for such a kind comment. ;)
So indepth and simplified,,,, I swear you are the Real Jesus Sir!!
I really appreciate this video, sir. 🙏
Thank you for your comment! If you enjoyed the video, don't forget to subscribe and turn on notifications to stay updated with all our UA-cam videos. 🤗 Additionally, for more learning opportunities, we invite you to sign up here and explore even more of our free content, along with all the study features that can help you ace your exams: lectur.io/freecontentyt
man this is probably the best
Thank you for the easy explanation.
omg thamk you so much!! Amazingly clear
Thank you :) We are glad to help!
this guy is really great
Amazing! So well explained.
So what's released is a NH2-R and COOH-R with the enzyme acting as catalyst, here it is seen that amine and an acid is released, this shows that serine protease releases acids and amines, so is the protease inhibitors targeted to supress the release of excess acids and amines, (in this case of the serine protease) of course there are other proteases but an analogy can be assumed
feels the mechanism for the last step of Ser to form the -OH group and release of carboxylic acid not correct. The tetrahedral intermedia, the central carbon formed five bonds, is that a mistake?
Hi, I was wondering is the lecturio app is free? What are the advanced course of biochemistry? Thanks
Great lecture
thank you sir🙏
Hi! I followed this to a T, thank you so much for explaining it in such depth. I do however have one question. Around 9:10, right when the NH2R gets released, and the remaining portion of the peptide covalently bonds to Serine, there seems to be a missing CH2 on the serine side-chain. I could be wrong, but that's the only part I am not following. Thank you again!
Hey! Thanks for checking us out.
Our lecturers do not use UA-cam but they will be happy to answer your question at www.lecturio.com/medical-courses/amino-acid-metabolism.course.
You need to register first and then will also have access to hundreds of other free medical videos.
It's beautifully explained. Thank you!
Really good! well explained and visualized
Thanks so much for your support!! We're happy you're enjoying the courses. Also feel free to create a free account at www.lecturio.com to get more free video courses.
Thanks a lot!! Very good explanation 👏👏
that was an awesome explanation. tysm. sir in 2 nd stem how come the carbon had double bond even after forming tetrahedral confirmation with oh here instead of nh in first step where it was a single bond.
+yash parikh Hello Yash, thx for your kind comment. As I am only the UA-cam manager at Lecturio Medical Education Videos, this detailed question is a bit to difficult for me to answer. But did you know that we also have an elearning plattform for medical education where you can watch even more free lectures and ask questions to the professors. Try for free at www.lecturio.com/medical-courses Thanks again!
Very helpful! Thank you!
Kevin Ahern
Thank you very much
Thank you 👏🏻
Amazing!
Thank You VERY much!!!!!
+Giselle Diazzi Hey Giselle, you are welcome! Thx for oyur nice comment and feel free to watch even more free lectures on www.lecturio.com Thanks again!
Why is there a slow and fast step?
thank you
THANK YOU :)!
You're welcome! Do you hesitate to start your FREE trial on our website/app to access much more valuable content: lectur.io/freecontentyt
Super clear and very helpful!!!! :D
Thank you, Elizabeth. You can also watch this video and many other free lectures at Lecturio: www.lecturio.com/ :)
Excellent explanation. Thanks a lot!