Mechanism of Chymotrypsin and Catalytic Triad

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  • Опубліковано 15 жов 2024

КОМЕНТАРІ • 245

  • @mohammadhussaini2815
    @mohammadhussaini2815 5 років тому +52

    I feel like I should pay you my tuition fees instead of paying it to my university, so sad can't do it. thanks mate helped safe my life from biochem

  • @kylecl12
    @kylecl12 9 років тому +252

    Hey just wanted to say that I love all of your videos. Currently in Biochemistry, and this is helping me out so much. You go more in depth than my professor but at the same time it is much easier to grasp! Thank you

    • @AKLECTURES
      @AKLECTURES  9 років тому +40

      +kyle clark Hey Kyle, thats wonderful to hear! Study hard and youll love biochem, its an awesome subject! :)

    • @thefenerbahcesk4156
      @thefenerbahcesk4156 6 років тому

      Did you guys have to memorize the whole mechanism?

    • @agiemylona2347
      @agiemylona2347 5 років тому +7

      @@thefenerbahcesk4156 I am doing a Biochemistry degree and we were told we have to know the mechanism. The key point is to understand the principles underneath (how it works, why it works that way, understand the flow of electrons) it so that you can be able to "solve" other mechanisms as well. Hope this is helpful :)

    • @debbyralph6136
      @debbyralph6136 3 роки тому +2

      What degree do you have now?

  • @Nitro0xide
    @Nitro0xide 9 років тому +74

    You are better than 99% of profs in the world. Thanks a lot for your videos!!

  • @jemiller8678
    @jemiller8678 9 років тому +107

    You've succeeded in making a semester where I'm taking PathMicro, Organic, AND Biochem seem just a little bit clearer. I can't explain how much sleep your videos have saved me and I can never thank you enough for the clarity your lecture bring.
    Seriously.
    You're awesome.

  • @kumquats2842
    @kumquats2842 3 роки тому +6

    a 15 minute video did a better job of explaining this than a 2 hour lecture from my professor. bless you my dude

  • @ro1882
    @ro1882 9 років тому +15

    hands down, you deserve a trophy for teaching this! Thank you!
    sincerely, from a student attending an overly overrated high ranking university!

  • @JBrimBloodG
    @JBrimBloodG 7 років тому +56

    my favorite educational 1.25x speed channel

    • @dovedon5583
      @dovedon5583 4 роки тому

      ...lolz... I guess I'm not alone.

  • @No2clarinet
    @No2clarinet 4 роки тому +8

    You are legitimately saving my grade right now! All of your videos are perfectly balanced with diagrams and knowledge. You don't overload us with minor details. Very well done!! Thank you so much

  • @mnoori100
    @mnoori100 9 років тому +12

    I literally watched 5 other videos and read the text on this topic only to get more confused than I started. THANK YOU!!!! I finally understand it clearly. By far the best explanation found!! You're always the best :)

    • @AKLECTURES
      @AKLECTURES  9 років тому +5

      Bella Thats wonderful to hear! thanks for watching ! :)

  • @nerdalert1496
    @nerdalert1496 8 років тому +16

    All of your videos are so helpful. Thank you so much for making them! You're saving many biochem students!

  • @kennethbutler9164
    @kennethbutler9164 5 років тому +1

    My dude. You explain things so well. So fluid. Thank you!!

  • @Freshtodeath2000
    @Freshtodeath2000 9 років тому

    I've watched a lot of lectures on the internet, read a lot of books in my lifetime. This is one of the best explanations I have ever seen in any subject, clearly spoken, not many mistakes and summarizes the "big picture" so at the end of the day you are taking home the right message.
    subscribing

    • @AKLECTURES
      @AKLECTURES  9 років тому

      teflon don thanks! I really appreciate that ! :)

  • @adesuwaomede7803
    @adesuwaomede7803 5 років тому

    Hands down the best mechanism explanation video I have ever watched. Thank you.

  • @user-gi6mh2dn7b
    @user-gi6mh2dn7b 8 років тому +2

    I hope you are interacting with college students (be it TA, prof, etc.) because your explanations are always concise and clear! You've helped me with my general biochem course on a level no one else has ever! I appreciate your work.

    • @AKLECTURES
      @AKLECTURES  8 років тому +2

      +R thanks, I appreciate that! I am doing something like that :)

  • @yuvalmohl8408
    @yuvalmohl8408 Рік тому

    you're most definatley the best prof ever, you made it so much simpler than what I initialy thought when I saw it. thank you so so much!

  • @rythammanhasfilms
    @rythammanhasfilms 3 роки тому

    Amazing Explanation, I am from India and don't have any trouble understanding your lectures. The clarity and depth with which you explain, hats off.

  • @Abby-in6tk
    @Abby-in6tk 11 місяців тому

    You sir have officially entered my list of "people I'd MUCH rather pay my tuition to". When my prof went over this, I was so overwhelmed. Now I at least feel I know the basics of what's going on here. If I survive biochem it's probably gonna be all thanks to you. Thank you so much for these videos 💙

  • @danielpie2046
    @danielpie2046 7 років тому +1

    Explaining mechanisms does not get better than this. Thank you so so much!!!

  • @genthomasset8377
    @genthomasset8377 6 років тому

    Please come teach at my school. At this rate, you're the reason why I passed / did well in orgo, immunology and hopefully now biochemistry. So helpful as always & thanks a million from a desperate college student.

  • @vietkutie001
    @vietkutie001 7 років тому +1

    OMG, just saved me!!! Been trying to find other resources to explain this process for weeks! Thanks so much!

  • @miminramzi6456
    @miminramzi6456 8 років тому

    thank you for existing! i have exam this evening and i can't understand a single step in my notes but you save my life. thank you so much!

  • @LifewithAmairanny
    @LifewithAmairanny 2 дні тому

    This was a true masterpiece, if I've ever seen one

  • @hellojmister
    @hellojmister 8 років тому

    Amazing the clarity with which you explained this - It really helps that you explain each step and why it happens instead of just describing what happens. I can't explain how poorly and confusingly my lecturer taught this.

  • @niralivachhani7560
    @niralivachhani7560 7 років тому +1

    Your videos are awesome! I struggled with biochemistry but your videos are really helping me, it makes easier for me to understand the concepts.

  • @violetlavi2207
    @violetlavi2207 2 роки тому

    Thank you for simplifying such a complicated mechanism!

  • @sandraz3466
    @sandraz3466 9 років тому +5

    I wish I had seen your videos earlier when I was taking some of my other hard science courses! I am taking biochemistry now and doing MCAT prep and you make the concepts so clear. Thank you so much for these videos and keep on spreading your knowledge! :)

    • @shaktiramnath6694
      @shaktiramnath6694 3 роки тому +3

      hey girl hope youre a successful doctor/med student right now

  • @Am-ug9np
    @Am-ug9np 7 років тому +1

    My teacher doesn't lecture, just tells us to teach ourselves out of the book then quizzes us for the entire class period. I need someone to explain things to me so this is literally saving me 👏 Thank you so much

  • @amsd5780
    @amsd5780 2 роки тому +2

    Thank you so much, so quick and clear ! It made this processus go from really scary to actually very interesting :)

  • @chueklamable
    @chueklamable 9 років тому +3

    much clearer than my notes~~~ thanks for your effort

  • @DR-kh9bl
    @DR-kh9bl 5 років тому

    thank you so much, what a life saver. this mechanism looked impossible to understand, but not anymore thank youuuuu.

  • @hankhill8044
    @hankhill8044 9 років тому +28

    In step 3 you should have an amine group leaving and deprotonating the histidine, not an amide.

    • @user-gi6mh2dn7b
      @user-gi6mh2dn7b 8 років тому +1

      +Hank Hill I was confused about this for a second. I'm glad I wasn't the only one who noticed! He did a fantastic job otherwise

    • @thefenerbahcesk4156
      @thefenerbahcesk4156 6 років тому

      Amine vs Amide what's the difference?

  • @daphnesilvertand
    @daphnesilvertand 2 роки тому

    I watched this a while ago and did understand then I forgot and I could not manage on my own for over an hour, then I watch this movie and in 10 min it is clear again! Amazing thanks!

  • @deemaalobaidi4630
    @deemaalobaidi4630 3 роки тому

    Your teaching style is amazing ...thank you!

  • @HardmanTech
    @HardmanTech 9 років тому

    First video in hm... 100 videos that I see and now I understand, then thank you bro!
    From Brazil.

  • @sakshisharma3297
    @sakshisharma3297 5 років тому

    You provide the best explanations on the most confusing topics... Thankyou so much for making learning easy.... Keep doing the good work... You really are being highly blessed by the students that get your help through the lecture.... Keep making videos on every little topic related to biochemistry and biotechnology....

  • @magkann
    @magkann 7 років тому

    you are A MILLION TIMES better at teaching than my professor!! I LOVE YOUR VIDEOS BLESS YOUR SOUL

  • @thanasisgiantzaklidis5497
    @thanasisgiantzaklidis5497 2 роки тому

    Once again, incredible and 110% explainatory video, I wish you were my university teacher!!!

  • @lauradumo
    @lauradumo 7 років тому

    Seriously, I love you!I don't even have to go to class anymore

  • @Jade-sv2wp
    @Jade-sv2wp Рік тому

    My gosh this helped me understand this mechanism so much better thank you so much TT!!!

  • @lyanadhamirah7381
    @lyanadhamirah7381 4 роки тому

    so glad I found your channel. Very well explained.Thank you so much!!

  • @thynguyen911
    @thynguyen911 7 років тому +1

    I can't thank you enough for making these biochemistry videos! You explain everything much better than my professor! THANK YOU (:

  • @DR-kh9bl
    @DR-kh9bl 5 років тому

    Thank you again I will watch this vid many times, even though I understood it from the first time, but you explain so beautifully and clear that makes me want to watch it again. it is so fun when u understand. thank you

  • @chabby_joe
    @chabby_joe 9 років тому

    You are a boss!!! I've got my biochemistry exam tomorrow and I feel really ready now thanks to you!!!! Keep up the amazing work!!!

    • @AKLECTURES
      @AKLECTURES  9 років тому +1

      Joe Charbine Thanks Joe, best of luck on your biochem exam! let me know how it goes.

  • @robertgrassi6285
    @robertgrassi6285 8 років тому

    Wow, bravo. Very clear, very comprehensive, very neat.

  • @bv8560
    @bv8560 8 років тому

    Hey just wanted to agree with everyone else and send my deepest thanks to you! This was three exam questions & I can confidently say I don't know what I would do without this video along with your other biochem videos. You rock!

  • @clarissagilmore
    @clarissagilmore 5 років тому

    you will probably be the reason I pass Biochem, I love you.

  • @IqraLiaqatspbsbt
    @IqraLiaqatspbsbt 2 роки тому

    Very well explained. It is very helpful thanks alot. May you prosper. Ameen

  • @tomiowoeye9407
    @tomiowoeye9407 5 років тому

    You make things make so much sense

  • @barbxrox
    @barbxrox 5 років тому

    U ARE AN ANGEL OF A HUMAN BEING!!!!! THANK YOU FOR DOING WHAT MY PROFESSOR COULD NEVER! school is a scam kids

  • @afaq289
    @afaq289 6 років тому

    Thank you so much for all videos you are doing. help me a lot in my biochemistry class.

  • @notagunexpert8117
    @notagunexpert8117 9 років тому

    You are saving me in Biochem right now! Thank you

  • @konvicteddestruction6183
    @konvicteddestruction6183 3 роки тому

    Thanks a lot for your videos! Its really helpful for our curriculum.

  • @tsewangladol8514
    @tsewangladol8514 8 років тому

    if u were my professor of biochem class,i would hav topped the class..u r an amazing teacher.thanku for the great videos

  • @minervagao7223
    @minervagao7223 2 роки тому

    Bro you save my life!!! Life saver!

  • @geraldinelee9230
    @geraldinelee9230 3 роки тому

    Best educational video, plus watching ur videos feels like riding a roller coaster phew

  • @gabrielatheismarchan7059
    @gabrielatheismarchan7059 3 роки тому

    geat explanation. Really helped me to understand better

  • @동쪽-z5v
    @동쪽-z5v 9 років тому

    respecting your teaching! thank you for your simple explanation.

  • @AriJeru
    @AriJeru 8 років тому

    This is so fantastic. Please keep it up, these are so so helpful

  • @skittless3949
    @skittless3949 9 років тому

    Great work! Clear, concise, and very helpful! Definitely subscribed and will spread the word about your amazing videos!

  • @tahirtantary7438
    @tahirtantary7438 2 роки тому

    Best ...Lots of Love from Kashmir...

  • @anshukamboj8615
    @anshukamboj8615 4 роки тому

    Thanku so much it helps me alot. Love from india

  • @sarahmoselyyy
    @sarahmoselyyy 7 років тому

    great explanation!! way better than my profs

  • @adityasiddharth6782
    @adityasiddharth6782 9 років тому

    That was a beautiful explanation...Love yours vids...Keep up the good work

  • @qraxulz4376
    @qraxulz4376 2 роки тому

    Zain Nassar loves your videos man ong

  • @kikicucci1910
    @kikicucci1910 5 років тому +1

    thank you so much so helpful for medical school

  • @nxph2108
    @nxph2108 7 років тому

    Sir you have been saving my ass every time i get serious the day before the exam. God bless u

  • @theranaxo
    @theranaxo 7 років тому

    Your videos are saving me in Biochemistry!
    I'm sure my whole class watches your videos haha, I wish you were my professor :(
    Thank you so much!!!!!

  • @kennethbutler9164
    @kennethbutler9164 4 роки тому

    Awesome job man. I wish I could give more than one like on this video

  • @kp9269
    @kp9269 Рік тому

    Amazing showstopping brilliant

  • @skittless3949
    @skittless3949 9 років тому +13

    5:04, you said asparte uses its full positive charge, I think you meant negative.

  • @Barbie4wido
    @Barbie4wido 9 років тому

    you are the best. awsome lectures.

  • @dejanvukovic9763
    @dejanvukovic9763 Рік тому

    This is the best explanation

  • @edene7354
    @edene7354 Місяць тому

    Thank you so much for this! It helped me so much!

  • @NguyenPham-fg7gi
    @NguyenPham-fg7gi 3 роки тому

    YOU MAKE SO MUCH MORE SENSE THAN MY PROFESSOR =(((( THANK YOU SO SO SO MUCH

  • @nathaliekirshman3335
    @nathaliekirshman3335 8 років тому

    Thank you, this was so clear and easy to understand!

  • @LlamasEatHotdogs
    @LlamasEatHotdogs 7 років тому

    Much better than my text, and prof just skimmed over it. Thanks for all the videos.

  • @fabolous989
    @fabolous989 7 років тому +1

    Fantastic explanation. Thank you!!

  • @aunmurtaza9964
    @aunmurtaza9964 9 років тому

    Amazing explanation, u know how to teach and explain. You should have also mentioned the Pka of Histidine and how it is increased making it a strong base.

  • @Jay-wy8uv
    @Jay-wy8uv 9 років тому +1

    nice lecture. easily understood! thx

    • @AKLECTURES
      @AKLECTURES  9 років тому

      안희태 you're welcome! :) thanks for watching

  • @oldaccountm3477
    @oldaccountm3477 6 років тому

    Thank you, this was very clear and helpful.

  • @kareem9102
    @kareem9102 8 років тому

    Wow. That was amazing explanation. Thank you very much.

  • @zarawarsi
    @zarawarsi Місяць тому

    Awsome lecture in just 12 mint❤

  • @אינהפיגלצוק
    @אינהפיגלצוק 4 роки тому

    Best lecture ever

  • @rimkenan4654
    @rimkenan4654 8 років тому

    Thank you you are saving my life!

  • @Larcen157
    @Larcen157 8 років тому

    great explanation ! thanks for the hard work.

  • @hamedhosseini4938
    @hamedhosseini4938 7 років тому

    Dude, You are legend. I wish you were still active and had your channel alive so you could make more videos. It's shame that you gone, nevertheless wish you all the best with your career.

  • @mirizapisotsky7778
    @mirizapisotsky7778 Рік тому

    amazing video! helped me a lot! thanks

  • @tejasshinde3006
    @tejasshinde3006 6 років тому

    Awesome explanation

  • @meganlehr7632
    @meganlehr7632 11 місяців тому +1

    i owe you my life

  • @valeriewarkins3704
    @valeriewarkins3704 4 роки тому

    Wow this was so clear, thank you!

  • @kr7638
    @kr7638 8 років тому +58

    I love you.

  • @dordor42
    @dordor42 7 років тому

    Amazing lecture! you helped me alot. thank you!

  • @sharonsequeira8080
    @sharonsequeira8080 8 років тому

    This was extremely helpful! Thank you so much!!

  • @SaraiGarage
    @SaraiGarage 5 років тому

    Amazing Video. Thank you 🙌🏾

  • @bitasadeghi7995
    @bitasadeghi7995 2 роки тому

    I feel like you are going to win a Nobel prize one day

  • @emmaforrester7677
    @emmaforrester7677 4 роки тому

    Your videos honestly are saving my biochemistry grade. These videos actually make me like the subject! Thank you so much!

  • @garciabreezy
    @garciabreezy 8 років тому

    Thanks a lot, it was a great help for me your explanation!

  • @joelryangeorge6557
    @joelryangeorge6557 3 роки тому

    One day, when I'll graduate, I'll return the favor, THANK YOU VERY MUCH!

  • @RVGENomini
    @RVGENomini 8 років тому

    Thanks for the video, it helped tremendously. I was curious if in step 2 whether the lone pair on nitrogen (instead of the N-C bond electrons) would attack the hydrogen on histidine. The arrow pushing just looks a little awkward going to the hydrogen instead of back on the nitrogen.

  • @akuchi
    @akuchi 2 роки тому

    this is beautiful. thank you so much