Neuroinflammation in Alzheimer's Disease: The Role of Microglia

  Learning objectives
Understand how microglia drive neuronal damage through phagocytosis and reactive oxygen species (ROS) creation.
Explore the role of flippase and scramblase in microglia-mediated neuronal damage.
Understand how annexins can provide insights into the process of microglia-mediated neuronal damage.
Learn how primary cell culture can be used as a tool for Alzheimer's research on microglia and neuronal interactions, including examining Nenistyte et al. 2011 research.

[@Lauralopezfed]

Very interesting and helpful video! You make it so easy to understand, thank you!

[@Daniel-fr8dt]

How do you equate the fact that some AD patients don't have an amyloid buildup? Perhaps the disease progression doesn't start with amyloid?

[@Daniel-fr8dt]

"Amyloid is not toxic without microglia"? This suggests that overactive microglia are the issue not amyloid. So much pointing in that direction.