How do ACE & ARB's Work? (+ Pharmacology)

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  • Опубліковано 22 лис 2024

КОМЕНТАРІ • 154

  • @DrugChug
    @DrugChug  4 роки тому +55

    Hope this video helps you out!!
    Consider Subscribing!
    😁

    • @WadcaWymiaru
      @WadcaWymiaru 4 роки тому

      I want ask you: do this drug interact with *serine protease inhibitor* ?
      (like camostat)

    • @dwielfirakurniati6333
      @dwielfirakurniati6333 3 роки тому +1

      thanks for making this video..
      very helpfull

    • @Bylinie
      @Bylinie 3 роки тому +1

      Thank you so much.... It's really help me..... After spending hours trying to read n understand the concept ... But still I'm not satisfy ..finally your vedio help me alot ,the way u explain its very easy to understand ...And obviously the quiz at last we can ans it without hesitation... Thank you so much.... May God bless u

    • @abdelmatlubbenmussa9392
      @abdelmatlubbenmussa9392 3 роки тому +2

      Outstanding presentation and teaching ... succinct and clear... congratulations

    • @kdjm1446
      @kdjm1446 3 місяці тому

      Hi, this is very helpful! And, I laways find that your videos are great! Please, may I take screenshots of your video to use for my uni presentation?

  • @FatimaIslam-p8t
    @FatimaIslam-p8t 8 місяців тому +4

    Your videos are way to effective. Why did you stopped uploading pharma videos.please upload more & more like those videos😢

  • @4evauniquelylatoya196
    @4evauniquelylatoya196 5 років тому +43

    Omg!!! It's ashame that I'm learning A LOT MORE from you than I did in my pharmacology class that costed me a lot of money! Lol! You are a great teacher and your lessons are FREE!! Thank you so much! PLEASE continue to upload your very informative and understandable videos!! 💖💖💖💖💖💖💖💖🙏🏾🙏🏾🙏🏾

    • @DrugChug
      @DrugChug  5 років тому +5

      Thank you for watching! Glad it helped!! And I truly appreciate the support!😁

    • @4evauniquelylatoya196
      @4evauniquelylatoya196 5 років тому +1

      @@DrugChug you're welcome! 🤗

    • @rockaidpharmacy1461
      @rockaidpharmacy1461 Рік тому

      Exactly. I have fallen in love with this channel

    • @gladisrodriguez7764
      @gladisrodriguez7764 8 місяців тому

      I’m currently studying pharmacology and this makes so much more sense!
      I was preparing to fail but may have found a lifeline

    • @nurat4496
      @nurat4496 3 місяці тому

      True😂

  • @Adaughtersheart-Isa53
    @Adaughtersheart-Isa53 5 років тому +19

    You are a really excellent teacher....I love the methodical way these are presented, organized and it helps to understand "why" which helps to memorize or actually learn the drug categories. You add a brief patho to start helps understand the MOA and the "which patients should avoid " which helps understand and side effects.

    • @DrugChug
      @DrugChug  5 років тому +1

      Thank you so much for your support! @Marlana I'm glad this teaching style is working!

  • @sarmadali8172
    @sarmadali8172 Рік тому +1

    You are the best teacher of the pharmacology

  • @dalilahreyes3477
    @dalilahreyes3477 2 роки тому

    It has taken me months to understand blood pressure medications .Finally they all make sense .Thank you

  • @patriciahess-goetz4552
    @patriciahess-goetz4552 5 років тому +3

    I am going back to get my ARNP at 52!!! and at Duke!!! and you are my new BFF!!! Helping this old brain break it down!!! THANK YOU!!!!!

    • @DrugChug
      @DrugChug  5 років тому +2

      No such thing as an "old brain" ! You got this! And I'm glad I can help!

    • @patriciahess-goetz4552
      @patriciahess-goetz4552 5 років тому +1

      @@DrugChug Everybody is getting a drug chug t shirt for xmas this year :-) I love the antibiotics one

    • @DrugChug
      @DrugChug  5 років тому +1

      I appreciate the support 🙂

  • @nicksix71
    @nicksix71 3 роки тому +4

    This is UNBELIEVABLY great ! Thank you, thank you, thank you!!

    • @DrugChug
      @DrugChug  3 роки тому +1

      Wow, thank you! I appreciate the support

  • @shavetadevesar
    @shavetadevesar 10 місяців тому +1

    Great explanation thank you so much sir for your time and efforts

  • @muhammadadil1948
    @muhammadadil1948 4 роки тому +2

    I really love your simplest and easiest way of teaching. Please teach to University professors who lack professional knowledge and getting salaries what they don't deserve

    • @DrugChug
      @DrugChug  4 роки тому +2

      Thank You for the support! Unfortunately, loving to teach comes within, and these professors who dont care will never teach effectivly.

  • @musikaaffection8570
    @musikaaffection8570 Рік тому +1

    Thank you soo much sir 🥰✌️

  • @bobrags1976
    @bobrags1976 2 роки тому

    I am an old woman pharmacist and I am thankful for the reviews

  • @starzthelimit3563
    @starzthelimit3563 4 роки тому +2

    This is the best explanation of these 2 drug classes. Thank you!!

    • @DrugChug
      @DrugChug  4 роки тому +1

      Thank You! Appreciate the support!😁

  • @tedbear6083
    @tedbear6083 3 роки тому +2

    Thanks so much for these videos! I'm a second year medical student and these have been really helpful

    • @DrugChug
      @DrugChug  3 роки тому +1

      You're very welcome! Glad to help! Now go ACE those exams!

  • @dannielibby7412
    @dannielibby7412 3 роки тому

    Learning Pharm for Dental Hygiene - thank goodness I found this!

  • @lykebila
    @lykebila 3 роки тому +1

    the best explanation, this is just awesome. You made it so easy to understand something that looked so hard for so long

    • @DrugChug
      @DrugChug  3 роки тому +2

      Thank you so much for watching! Glad it helped!😁

  • @knight8821
    @knight8821 Рік тому

    Very helpful knowledge with someone just diagnosed with high blood pressure

  • @esterindahkusumaputr
    @esterindahkusumaputr 4 роки тому +2

    Thank you so much, and now i'm getting ready to write my thesis!

    • @DrugChug
      @DrugChug  4 роки тому +1

      Woohoo! That's awesome to hear! Good Luck😁

  • @adal8653
    @adal8653 2 роки тому

    This is the best video in all the videos that explained ACE& ARB❤❤❤

  • @maryhasaballa4052
    @maryhasaballa4052 5 років тому +3

    This is amazing! I hope there will be more episodes coming up soon!

    • @DrugChug
      @DrugChug  5 років тому +1

      Thank you for the support! More videos are being worked on as we speak! 😁

  • @christinajoanne8177
    @christinajoanne8177 5 років тому +8

    Absolutely love this! Thank you so much for your hard work! Would absolutely love if you could do more on vasopressors or inotropes! Thanks again my friend :D

    • @DrugChug
      @DrugChug  5 років тому +3

      You're welcome @Christina ! More videos are planned and will be released soon! Vasopressors and ionotropes are on the list!

  • @Mohammed-dd8jm
    @Mohammed-dd8jm 4 роки тому +2

    very interested video thank you please we need more interested video

  • @TheMonnybonny
    @TheMonnybonny 2 роки тому

    WOW. AMAZING. so many different videos..but your video was the only one I felt was made it extremely simple to understand. Thank you.

  • @rashidchak8945
    @rashidchak8945 Рік тому

    fantastic explanation sir,requesting to continue your fantastic explanation.

  • @speaksoftlylove7988
    @speaksoftlylove7988 5 місяців тому

    Best pharma channel ever !!!!

  • @naj1450
    @naj1450 3 роки тому +2

    Very clear explained. Thanks

    • @DrugChug
      @DrugChug  3 роки тому +1

      Thank you for watching!

  • @lnperez3043
    @lnperez3043 4 роки тому +2

    Excellent !!! Please make videos on anti-arrhythmias drugs . Thank you !

    • @DrugChug
      @DrugChug  4 роки тому +2

      Thank you! and Yes! Those videos are already in the pipeline!

  • @yulimedrano818
    @yulimedrano818 3 роки тому +1

    Amazing videos! Helping me study in nursing school!

    • @DrugChug
      @DrugChug  3 роки тому +2

      Thank you so much! Feel free to share with your class! 😁

  • @RajwinderKaur-pm1pb
    @RajwinderKaur-pm1pb 3 роки тому

    I have pharmacology exam on Tuesday and this helped me a lot. I love it 🥰 Thank you so much Sir!!

  • @evangelinelawrence9783
    @evangelinelawrence9783 6 місяців тому

    11:58pm thank you for explaining

  • @27capricia
    @27capricia 4 роки тому +1

    This is so awesome. Thank you so much for your time. Do you have a video on ABGs? Would you please consider making one ? As a nursing student your videos are saving me right now. Thank you.

    • @DrugChug
      @DrugChug  4 роки тому +3

      Thank you 27capricia, keep studying hard! There are more videos planned such as ABGs. But due to the time it takes to make these videos, it may take some time to make!

  • @gloriac9994
    @gloriac9994 3 роки тому

    ugh i love you sm. u are saving my butt for this exam

  • @jacquelinekelman1065
    @jacquelinekelman1065 5 років тому +1

    Really awesome video! Helped me a lot, wouldn't be able to pass pharmacy school without this! Thanks!!!

  • @samuelofosu2231
    @samuelofosu2231 4 роки тому +1

    How u relax n speak make me understand well

  • @beawesome5090
    @beawesome5090 4 роки тому +1

    Perfectly explained. Thanks

    • @DrugChug
      @DrugChug  4 роки тому +2

      Thank you Razin! Appreciate the support!😁

  • @N.Anitha-v9q
    @N.Anitha-v9q 9 місяців тому

    Your are a amazing teacher ,it is easy to understand .ur all vdeos are amazing. I requesting u to make a vdeo of cholinergic drug sir.

  • @sunrunnernge560
    @sunrunnernge560 5 років тому +2

    absolutely love your channel! top notch

    • @DrugChug
      @DrugChug  5 років тому +1

      Thank you so much for the support!😁

  • @rebeccagonzalez2407
    @rebeccagonzalez2407 3 роки тому +1

    Amazing explanation! Thank you so much!

    • @DrugChug
      @DrugChug  3 роки тому +1

      Thank you for watching! :)

  • @beningembun7719
    @beningembun7719 5 років тому +3

    Please make video about drug interaction,how to classify it pharmacodinamic or pharmacokinetic

    • @DrugChug
      @DrugChug  5 років тому +2

      Great idea! More videos are planned and I will add this to the list!

    • @beningembun7719
      @beningembun7719 5 років тому +1

      @@DrugChug i'm so looking forward for it..thank you

  • @sanatombikhumanthem1246
    @sanatombikhumanthem1246 2 роки тому +1

    Sir please upload more 🥰

  • @keemyam9408
    @keemyam9408 4 роки тому +2

    Amazing video so simple and understandable thanks to you ♥️

    • @DrugChug
      @DrugChug  4 роки тому +2

      Thank you for the support!😁

  • @hardik8191
    @hardik8191 3 роки тому +1

    A very well explained video. Thanks

    • @DrugChug
      @DrugChug  3 роки тому +1

      Thank you so much for watching! 😃

  • @lilym8451
    @lilym8451 3 роки тому

    I'm a visual learner and this is amazing content you have!! It actually makes sense and I can follow along! Already subscribed, I'm trying to memorize the top 200 for the ptcb this is gold!

  • @100lanka
    @100lanka 3 роки тому

    Excellent teacher, what a clear lecture.

  • @MustReason
    @MustReason 3 роки тому +1

    The primary BP lowering effect of ACE/ARB is achieved by interfering with vasoconstriction. The loss of sodium and water is secondary.

    • @Emily-if4wi
      @Emily-if4wi Рік тому

      Was wondering why this wasn't mentioned in the video--thanks for building on!

  • @goahead3654
    @goahead3654 3 роки тому +1

    wow I am so happy I found this channel!!! Such precise information and beautiful explanation!! Thank you so much sir!
    I wanted to hear a lot more explanations from you, but your channel seems to have only few videos..
    Please make more videos!!!!!!! I would love to learn from you.🙏🏻🙏🏻

    • @DrugChug
      @DrugChug  3 роки тому +1

      Thank you so much for your support! More videos to come!

  • @neetukaur8517
    @neetukaur8517 3 роки тому

    Ans1-diovan
    Ans2- ACE
    Ans3-losartan

  • @IsabelRodriguez-nv2ue
    @IsabelRodriguez-nv2ue 3 роки тому +1

    Formidable!!! Thanks a million!!!

  • @lahirudissanayaka-mk8sq
    @lahirudissanayaka-mk8sq Рік тому

    superb explanation & I really love this channel ❤❤❤

  • @linkim4157
    @linkim4157 4 роки тому +4

    Thank you for the great video! Ive learn a lot from this video!
    Question! So if ACE inhibitor/ARB reduce the sodium and water retention, does it mean these medications can also be diuretic?
    If so, then why would they make hyperkalemia if they can be diuretic?
    Thank you!

    • @DrugChug
      @DrugChug  4 роки тому +4

      Thank you Lin for the support!
      ACE & ARBs do reduce some sodium and water retention, however it isnt a main mechanism. When compared to Thiazide and Loop diuretics-ACE's & ARB's are negligible so we cant consider them as a diuretic.
      When we talk about diuretics, there are 3 types and they focus on 1) different parts of the kidney and 2) Different electrolytes. One class of these diuretics are called "Potassium sparring diuretics", meaning they let go of all other electrolytes (Na, Ca, Cl) and hold onto potassium (K+). The reason I bring this up is that just because something is a diuretic or has diuretic-like properties, it doesn't automatically indicate hypokalemia. These ACE and ARB medication just promote the holding of potassium specifically. Thats why we see hyperkalemia!
      Hope that clears somethings up for you!

  • @MicheleMancusoishere
    @MicheleMancusoishere 4 роки тому +1

    Excellent video but I don’t understand why you only talk about the effects of angiotensin on the kidney without mentioning the effects on the arteries, heart and nervous system

  • @bahjatabuhamdan4838
    @bahjatabuhamdan4838 3 роки тому +1

    So nice presentation .

    • @DrugChug
      @DrugChug  3 роки тому +1

      Thank you for watching!

  • @omkarkalaskar3009
    @omkarkalaskar3009 4 роки тому +1

    I like the way u explain and I fully understand this concept,pls make video on drug used in CHF and it's pharmacology

    • @DrugChug
      @DrugChug  4 роки тому +1

      Thank you so much for watching!😁 yes more videos are planned!

  • @rashidchak8945
    @rashidchak8945 Рік тому

    Wonderful lecture,

  • @kellymudford7635
    @kellymudford7635 5 років тому +1

    love all these, find it so helpful can you make one about NSAID's

    • @DrugChug
      @DrugChug  5 років тому +3

      Ofcourse Kelly! More videos coming out in the future, and NSAIDs are definitely on my list!

  • @nataliewilson3957
    @nataliewilson3957 4 роки тому +1

    more videos please

  • @louisemcelhill5748
    @louisemcelhill5748 2 роки тому

    Excellent video. I would have liked to hear more about side effects of ARBs. Ive been on Telmisartan for one month and am having a few issues. But what is really more than a nuisance, is dry eyes, which I assume is d/t this drugs effects. I wear RGP contact lenses so this is very annoying.

  • @MrNick11177
    @MrNick11177 3 роки тому

    Your Videos are a God sent!...Thank you soooo Much, it is much appreciated!!!

  • @happyamoah6241
    @happyamoah6241 4 роки тому +1

    I wish you explained the hyperkalemia side effect.

    • @DrugChug
      @DrugChug  4 роки тому +1

      This side effect requires more explanation in the hormonal process of the body. But in general, ACE's and ARB's effect the hormone level of aldosterone with make the kidneys hold on to potassium more, causing hyperkalemia
      Hope that clears things up!

  • @shahmirhosseinzadeh3122
    @shahmirhosseinzadeh3122 4 роки тому +1

    I love this video. Thank you very much

  • @yuliakogan4160
    @yuliakogan4160 Рік тому

    Thank you! Great content!

  • @سجادمحمدعليعبدالباقي

    Thank you so much for your hard work

    • @DrugChug
      @DrugChug  4 роки тому +1

      Youre very welcome. Thank you for watching!😁

  • @cjreddy2607
    @cjreddy2607 2 роки тому

    excellent lecture, thank you Sir

  • @anthonynchabeleng2664
    @anthonynchabeleng2664 Рік тому +1

    What about headache as a side effect?

  • @sarezhmohammed1103
    @sarezhmohammed1103 4 роки тому

    Thanks for sharing this amazing video, it was really useful. As a nurse, I benefited from this. But there is a question: you say that our kidney has Angiotrnsin one receptor, but how can Angiotensin two bind to it?

    • @mobayoakin899
      @mobayoakin899 3 роки тому

      The receptor is actually called angiotensin 11 type 1 receptor

  • @mnwu2n
    @mnwu2n 2 роки тому

    Nice presentation..❤️❤️❤️

  • @Pharmakonacademy1
    @Pharmakonacademy1 4 роки тому +1

    Make video on antivomiting drug

  • @larajayebarron1393
    @larajayebarron1393 2 роки тому

    I find these videos so helpful! Could you do one on potassium channel blockers if you get the chance please, I’m struggling with the antiarrhythmics

  • @shahadf2844
    @shahadf2844 9 місяців тому

    I just clicked the like button before even watching the video❤️

  • @healthandsprituality
    @healthandsprituality Рік тому

    Angiotensin 2 binds to receptor of angiotensin 1? 2.32

  • @Allthingsmaci
    @Allthingsmaci 2 роки тому

    Thank you!

  • @BigTough
    @BigTough 4 роки тому

    I do not see Perindopril here on your list of prils. (or Perindopril Erbumine?) Mine is an 8mg combo with Indapamide 2.5mg.
    Can you make a video on ACE Inhibitors and how to avoid lifestyle habits that may work against the medication straining the heart or perhaps what might even amplify it dangerously? Like diets(certain foods), types of exercises, and how much, certain supplements, other medications like anti-depressants, particularly SSRI medication, benzodiazepines, metformin, Salbutamol, and even how certain drugs and /or alcohol may affect the body while taking this medication?
    I read somewhere that ACE inhibitors are very powerful, powerful enough to completely stop even certain methamphetamine processes in the body. And is it true that if you have been taking a Pril for years and then stopping it, the effects of the medication can last nearly a month or longer? Anyways, thanks!

  • @jaylee842
    @jaylee842 Рік тому

    Wow... Thanks a millions. 🎉

  • @saeedbadar3224
    @saeedbadar3224 3 роки тому

    Thank you Sir

  • @ethelrizarri2614
    @ethelrizarri2614 2 роки тому

    Very knowledgeable, OMG now i know

  • @lydiapereira1942
    @lydiapereira1942 2 роки тому

    Excellent Video . I have a condition called Atrial Fibrillation and I experience heart palpitations only when I have high Blood pressure . I am 82 years old. I take Bisoprolol 2.5mg. I was prescribed 4 different types of blood pressure drugs and I have very serious side effects.
    I tried Amlodipine, Candisartan, Indapamide
    Felodipine and Ramipril.
    I have been on Bisoprolol for over 3 years but for the last 6 months my blood pressure reading is over 150/75 The only drug that I don’t have any side effects is Ramipril. But my Doctor says it is affecting my kidneys.
    I don’t have diabetes. Could you suggest which drug I should try ACE Inhibitors that are safe for kidneys.
    All the above drugs cause increase irregular heart rate and arrhythmia, dizziness.
    Only Ramipril works on me but Doctor is not in favour.I should be very grateful for your reply.Thanks.

    • @Emily-if4wi
      @Emily-if4wi Рік тому +1

      Healthcare professionals can't diagnose or prescribe medications on UA-cam, but given your health history, you might benefit from finding another doctor in your area and getting a second opinion. Best wishes!

  • @Celtic_Iron
    @Celtic_Iron 2 роки тому

    Thank you for the amazing video. I managed to have an case of angioedema from 20mg of Telmisartan. It was mild and managed with histamines but does this mean all other ARBs are out for treating high BP ? Im an endurance athlete so trying to avoid cardio effective medications and was considering Losartan.

  • @minashah8168
    @minashah8168 4 роки тому +1

    OmG you are so brilliant 🌸

    • @DrugChug
      @DrugChug  4 роки тому +1

      Thank you for the support! 🙏

  • @emmelinejulien711
    @emmelinejulien711 Рік тому

    Wich medication naturel you can take for lawyer blood pressure

  • @aliarahaman4998
    @aliarahaman4998 Рік тому

    Very good

  • @dipeshmaladkar
    @dipeshmaladkar 4 роки тому +1

    Very nice video.

    • @DrugChug
      @DrugChug  4 роки тому +2

      Thank you! Appreciate your support!😁

    • @JOHNNIEUSA
      @JOHNNIEUSA 4 роки тому +1

      do You Have reveiw COURSE FOR usmle step 1... the level of teaching is amazing and loud and clear.. GREAT VOICE

  • @comcfi
    @comcfi 3 роки тому +1

    Would there be a reason for a doctor to prescribe an ACE inhibitor with an ARB?

    • @DrugChug
      @DrugChug  3 роки тому +1

      Always discuss with your doctor first when making a plan to treat.
      But typically No. There shouldn't be an ACE plus an ARB because it can dangerously lower blood pressure.

  • @anjayyadav6735
    @anjayyadav6735 4 роки тому

    Sir plz make more videos on drugs.

  • @dianewema7642
    @dianewema7642 3 роки тому

    You are amazing!

  • @tishabrown9576
    @tishabrown9576 Рік тому

    Your the best ❤

  • @baljinnyamamaraa9077
    @baljinnyamamaraa9077 Місяць тому

    Thank u 🎉

  • @dipadebnath5734
    @dipadebnath5734 2 роки тому +1

    Why don't you post new videos?

  • @almadiaz3236
    @almadiaz3236 4 роки тому +1

    Tank you

    • @DrugChug
      @DrugChug  4 роки тому +1

      You're very welcome!😁

  • @drawais924
    @drawais924 3 місяці тому

    Last quiz answer?

  • @tigerkahoy3822
    @tigerkahoy3822 4 роки тому +2

    Bravo

  • @edoc431
    @edoc431 3 роки тому

    Does long term use of ace inhibitors cause ckd?

  • @marieminani6978
    @marieminani6978 3 роки тому

    How bradykinin naturally cause increase in BP

  • @sivareddy7781
    @sivareddy7781 4 роки тому +1

    Why can’t I like 100 times

    • @DrugChug
      @DrugChug  4 роки тому +1

      Thank you! I wish you could too haha!

  • @missfatima7829
    @missfatima7829 4 роки тому +1

    where are answers to the quiz?

    • @DrugChug
      @DrugChug  4 роки тому +1

      In the description below!

  • @WadcaWymiaru
    @WadcaWymiaru 4 роки тому

    There is something wrong with the video. See:
    ua-cam.com/video/1vZDVbqRhyM/v-deo.html
    there is two "receptors" for angiotensin-2?
    Or maybe only one, and the other is just a proteine?
    Or this is the serine protease stuck to receptor?

  • @Mannydingo30
    @Mannydingo30 3 роки тому

    Bro you are the shit

  • @daniloonate5406
    @daniloonate5406 3 роки тому

    A

  • @killogram1ful
    @killogram1ful 2 роки тому

  • @anjananeupane1721
    @anjananeupane1721 5 місяців тому

    I don't found what I actually search for

  • @dalilahreyes3477
    @dalilahreyes3477 2 роки тому +1

    It has taken me months to understand blood pressure medications .Finally they all make sense .Thank you