Hi Chug, I just wanted to say thanks for this detailed, informative and high quality presentation of calcium channel blockers. I work in Cardiology and have been wanting to better familiarize myself with common medications' mech of action instead of just knowing "this medication reduces blood pressure". Learning the "how" of something always helps information stick for me. I hope you are planning to continue making videos. This is the first one I've watched on your channel, but it won't be the last. Stay safe! Mahalo
You've got a new subsciber here, i love the way you are describing each point. I really appreciate your effort, and the pace is slow, making it easier to understand!
Chug, Thank you very much for your Videos! It helps to understand what neither doctors, nurses or pharmacists don't have time or patience to explain to people who must take these medications and their relatives.
Just subbed after watching your nitrates video! I'm taking pharmacology rn and prepping for a unit exam and your videos and explanations are so concise and leave no info out! thank you so much for making these!!
To start I’m not a doctor. But I play one on occasion. JK. I had three years of college on a science degree but I could not afford to continue so I had to drop out. That said I have a bunch of medical issues, a spinal cord injury causing L1 paraplegia, hypertension, morbid obesity, lymphedema, and chronic back pain. Because of my hypertension I take four medicines, lisinopril, amlodipine, bisoprolol, and nifedipine. Since I’ve been prescribed so many medicines to control my blood pressure I felt it important to research what these drugs do. Thank God for UA-cam and Your channel which has provided me with a lot of information to help me understand. I want to say thank you for that, and commend you for your style of presentation. Thank you again.
So what happens to the calcium that is blocked? For instance if the kidneys or other organs are sending a signal to raise BP, and someone is taking Amlodipine, what does the body do? Are the side effects permanent?
Great question! When your blood vessels dilate, a drop is blood pressure will result. Because the blood vessels are relaxed, the flow of blood is lessened to the brain (because of gravity) This is normal, and we see it in alot of patients. Hope this helps!
I took Amlodipine for 21 years, now I'm dealing with a couple of muscle tendon tears. Try to take some other type of medicine, none if you can help it.
Thanks for the excellent info and drawing chart. Nice job and surely recommend you. Sorry I don't do subscriptions though. Really really thankful. Keep up the good job please. Attempted to subscribe.
I’m currently on amlodipine for hypertension and have been now for several weeks…how long before it actually starts working? Went back to my doctors for a follow up they took my BP….220/114 Left arm….202/111 Right arm. I’m at a lost.
Thanks for the explanation I am taking nfiedipine and it works a lot better for me I feel fine now. The Beta blocker made me feel next to death. Yuk. I got vertigo with the Beta blocker Metaprlol and vomited all day and night. I thought I would die. Got a new doctor he prescribe me Nifedipine it works well for me. I feel great! I dont fall down now. I am really liking the Nifedipine. New doctor is an Ace. He is an expert in all felds wow. My health care provider suggested him Im very happy with this guy. He is not a rookie like my old doctor. Only thing is this drug might cause me weight gain but my BP is under control now. It was crazy high. I also took some prednesone I had from a while back its helping me feel better too. I dont understand that part about blood viens leaking into your feet I get that too. The preds are probbly stoping that now. I started riding my elipticle as much as I can to combat the weight gain and dibeties. Hope this all turns out well. So far I feel great. 100 percent difference. my leg even stopped hurting me.
Dihydropiridines like Amlodipine cause vasodilation only in gromerular afferent arteries while the non-dihydropiridines (diltiazem, verapamil) make the same in afferent and efferent arteries improving glomerular function and diminishing the proteinuria
Hi dr.Chug, I am using Bisroprolol 5mg and marcomar 3mg. I use Magnesium sulfide (absenbsalt) sometimes for my health. Can this sipplemant interfere with my Last result withmy INR was 7.7. It is stated that my value has to be between 2 and 3. Isit possible that mgnesium interfering with my blood inr, Although I don't use the magnesium anymore. I get a terible headace in the morning when I wakeup. I have a Aotha valve sinds 2013. No problem with the heart. Than you Chug.
calcium channels? Are these calcium pumps like calcium ATPase or are they. calcium specific pores? what is the difference between the two types of channels?
If a patient has uncontrolled hypertension, then we do not want to give NSAIDs. This is because it will raise their blood pressure more, a better option would be tylenol (paracetamol).
I have candesartan after half year ussing this i have 8000x per day extrasystoles before ussing this i have nothing can candesartan make me extrasystoles ? Thanks for answer
The most important and effective time in 16 minute in my life
the most effective 16 minutes in my life!! thank you so much!!
You're welcome! Im glad it helped!!
Have you take this block in your ankle?
So true ❤️
1000000%
You are better than my pharmacology professor!
First time understanding the mechanism so well and never forgetting it again
Thank you and please keep up this excellent work
I love how organized and how well you pace yourself when explaining the concept. Definitely gonna subscribe!
Thank you Brittany! I appreciate the support!😁
Hi Chug, I just wanted to say thanks for this detailed, informative and high quality presentation of calcium channel blockers. I work in Cardiology and have been wanting to better familiarize myself with common medications' mech of action instead of just knowing "this medication reduces blood pressure".
Learning the "how" of something always helps information stick for me. I hope you are planning to continue making videos. This is the first one I've watched on your channel, but it won't be the last. Stay safe! Mahalo
Thanks Madi! I appreciate the support and thank you for everything you do in the healthcare field!😁
This channel is the goat. I wish he had videos on all the meds I need to know. When he teaches it's so easy to understand the information!
recently have my second stroke they gave millions of medications now i knwow why my legs are swollen . thanks a lot !!!!!
You've got a new subsciber here, i love the way you are describing each point. I really appreciate your effort, and the pace is slow, making it easier to understand!
Thanks!
Chug, Thank you very much for your Videos! It helps to understand what neither doctors, nurses or pharmacists don't have time or patience to explain to people who must take these medications and their relatives.
Your teaching is great ... I have studied this and it is confusing to remember. After your video I understood everything.😍☺️
Just subbed after watching your nitrates video! I'm taking pharmacology rn and prepping for a unit exam and your videos and explanations are so concise and leave no info out! thank you so much for making these!!
Hey what did u stop posting videos pls come back 😭😭
😂😂😂😂😂😂😂
I've watched lots videos about ca blockers, but bro this was most effective, thank you so much, you done great job
Your videos are by far the best on youtube
Loved it , you made it so easy to understand, short and to the point, thank you :)
Thank You! @Sarah I appreciate the support! More videos coming in the future!
you are saving my life in my nursing pharm class. keep up the amazing work. you make pharm easy and fun to learn about.
Glad these videos are helping! Keep on studying hard!
Hi
To start I’m not a doctor. But I play one on occasion. JK. I had three years of college on a science degree but I could not afford to continue so I had to drop out. That said I have a bunch of medical issues, a spinal cord injury causing L1 paraplegia, hypertension, morbid obesity, lymphedema, and chronic back pain. Because of my hypertension I take four medicines, lisinopril, amlodipine, bisoprolol, and nifedipine. Since I’ve been prescribed so many medicines to control my blood pressure I felt it important to research what these drugs do. Thank God for UA-cam and Your channel which has provided me with a lot of information to help me understand. I want to say thank you for that, and commend you for your style of presentation. Thank you again.
I love the wonderful video.
Wonder the Amlodipine dosage- it ranges from 2.5mg to 10mg.
This type of content will always be helpful for any type of people. Thank you Sir 🙏🇮🇳
I have learned a lot the images, presentation s were very helpful for us to understand, thanks
Thank you so much for watching!
You just saved my life oh my god everything make sense now !!! Thank you so much for your videos, they're amazing !!
Thank you explained very simply and in a organized way
Thank you for watching!
Thank you so much for this video and the others. I finally understand the concept. Best video.
Thank you for watching!
This was such a helpful video!! But I think the dosing at 3:51 for amlodipine might be a mistake?
Yes! It was typed out incorrectly. It should be 10mg daily MAX
What a brief and valuable explanation !
you have really simplified it made teaching interesting
Glad you enjoy the videos Aditya! More videos coming in the future!
watched so much videos but this is the best i got❤❤❤ keep posting dude you are superb
Great video thanks, my comment is on their use in pts with heart failure...there's a role there too
So what happens to the calcium that is blocked? For instance if the kidneys or other organs are sending a signal to raise BP, and someone is taking Amlodipine, what does the body do? Are the side effects permanent?
Great video! I believe you have the dosages backwards between Amlodipine and Felodipine on your powerpoint.
outstanding teaching. please continue
A very amazing video! Thank you
Thank you for watching!!
Thank you so much for this!! Hope you make more videos about other common drugs.
wow!!!! awesome video!!! very helpful information. thank you very very much. you're the best!!!!
You're welcome @Roland Altidor ! Glad you enjoy the videos!!
Thank you for the information.
Thanks for explaining about channel blockers l take lercanidipine as l have high calcium in my blood. Problem with my parathyriod
Thank you for your good quality of lecture.
Glad it was helpful!
you sir just earned a subscriber
Thank you so much!😁
count me in!
Super and short oraganization . Thank lot of sir
❤️❤️❤️❤️ the way u explain lil things also thanku so much sir
Glad you enjoyed it! More videos to come!
Excellent explanation very clear perfect👍🏼👍🏼👍🏼
Excellent teaching
Thank you so much for watching!)😁
Excellent!!! Really thanks you.....one quick question.....why vasodilation cause headaches?
Great question! When your blood vessels dilate, a drop is blood pressure will result. Because the blood vessels are relaxed, the flow of blood is lessened to the brain (because of gravity) This is normal, and we see it in alot of patients.
Hope this helps!
I took Amlodipine for 21 years, now I'm dealing with a couple of muscle tendon tears. Try to take some other type of medicine, none if you can help it.
New subscriber here..Very well explained. I believe that i will never forget CCB agsin.Sad that i didn't find this when i was in college
This is exactly why I make these! Thank you for your support 😃
thanks for the awesome content still hold up till this day
Excellent work done.infact u ve explain the thing well
Thank you so much for watching! 😃
Thanks for sharing this wonderful information it's very easy to understand really thank you
Glad you enjoyed! Keep on learning! 😁
hi the usual dose of Norvasc is 5 to 10g once a day. please recheck this in the video. love your videos keep it up!!!
mg not g.
Does less contractility of heart muscle contribute to peripheral edema because of less pumping action ? thanks
Can you talking about nuromusclear blockers as rocoronium or cisatracurium
clear stated.great job
Thanks for watching!
thank you for this good information
Thanks for the excellent info and drawing chart. Nice job and surely recommend you. Sorry I don't do subscriptions though. Really really thankful. Keep up the good job please. Attempted to subscribe.
Excellent information. Thanks.
Amazing video🙌🙌🙌
I absolutely loved it!!
Thank you for watching! :)
I’m currently on amlodipine for hypertension and have been now for several weeks…how long before it actually starts working? Went back to my doctors for a follow up they took my BP….220/114 Left arm….202/111 Right arm. I’m at a lost.
What an awesome video! Good work. Great job of explaining the physiology.
Thank you so much for your support!😁
Deep thanks for your teaching,”
Could ccb be used in diastolic heart failure?
Thanks for the explanation I am taking nfiedipine and it works a lot better for me I feel fine now. The Beta blocker made me feel next to death. Yuk. I got vertigo with the Beta blocker Metaprlol and vomited all day and night. I thought I would die. Got a new doctor he prescribe me Nifedipine it works well for me. I feel great! I dont fall down now. I am really liking the Nifedipine. New doctor is an Ace. He is an expert in all felds wow. My health care provider suggested him Im very happy with this guy. He is not a rookie like my old doctor. Only thing is this drug might cause me weight gain but my BP is under control now. It was crazy high. I also took some prednesone I had from a while back its helping me feel better too. I dont understand that part about blood viens leaking into your feet I get that too. The preds are probbly stoping that now. I started riding my elipticle as much as I can to combat the weight gain and dibeties. Hope this all turns out well. So far I feel great. 100 percent difference. my leg even stopped hurting me.
Thank you for your education.
You're welcome! Glad it helped!😁
Very basic information thank you
You are welcome!
Thank you so much ! Excellent job .
Thank you for watching!
Excellent lecture !!! Thanks
You're very welcome! Glad it helped!😁
How does non DHP CCBS reduce proteinura in patient with diabetes ?
Dihydropiridines like Amlodipine cause vasodilation only in gromerular afferent arteries while the non-dihydropiridines (diltiazem, verapamil) make the same in afferent and efferent arteries improving glomerular function and diminishing the proteinuria
Thanks
Amazing video
U made it very very very very very easy to understand 👍
Can worsen Anxiety and Flushes
Can NON-DHP effect Metformin ER breakdown in liver?
Bravo! veryy detailed! loved it
Hi dr.Chug, I am using Bisroprolol 5mg and marcomar 3mg. I use Magnesium sulfide (absenbsalt) sometimes for my health. Can this sipplemant interfere with my Last result withmy INR was 7.7. It is stated that my value has to be between 2 and 3. Isit possible that mgnesium interfering with my blood inr, Although I don't use the magnesium anymore. I get a terible headace in the morning when I wakeup. I have a Aotha valve sinds 2013. No problem with the heart. Than you Chug.
Can I use amplodipine with betablocker b1b2
thank you.
Thank you for the support!
Love how you explained i can catch up
I am intelligent however, would be more intelligent if I had an instructor that instructed like you !!!!
great video. can i use this video as training and education for my team? thanks in advance.
PLEASE PLEASE MAKE more sych videos in pharmacology of all important concepts
calcium channels? Are these calcium pumps like calcium ATPase or are they. calcium specific pores? what is the difference between the two types of channels?
Your videos are amazing as always and I am really interested in the programme that you use to make them ?
I appreciate the support!😁
This is the program I use!
paykstrt.com/2073/37882
thank you very much! love your channels!
Is NSAID contradict to the patient with hypertension consuming hypertensive drug ?
If a patient has uncontrolled hypertension, then we do not want to give NSAIDs. This is because it will raise their blood pressure more, a better option would be tylenol (paracetamol).
Is it ok to use verapamil for payroni deseas.?
how ACE inhibitor decrease peripheral edema in the patients that recieve CCB's..?
I have candesartan after half year ussing this i have 8000x per day extrasystoles before ussing this i have nothing can candesartan make me extrasystoles ? Thanks for answer
Sir i wanna ask u that why are u not uploading new videos on different categories? Waiting for new videos...2020
Hey Arslan! More videos are planned, but they take a while to put together! Next video is almost done! Stay tuned
@@DrugChug waiting for more as ur explanation way is outstanding.
Great work
Please add more videos .......thanks..
More videos are on the way!
explained very well
How bout Perindopril ?
Perindopril is an ACE inhibitor
thx alot .. this was very good and interesting 🌹
You are very welcome!
Does taking 240mg (2×120mg) Verapamil and 1.5mg Bisoprolol daily a conflicting combination?
Thanl you Doctor Chug
You are good! I learned a lot! Thank u.
i love your videos! it helps me with my review, i hope you do more videos. :)
Thank You for the support! 😁 And more videos are planned and being worked on! Stay tuned
Wow thank you I am glad I stumbled on your videos ❤❤❤
Hey again brilliant video!!
Could you please please do one on breast cancer by December have an exam on it ! Specially the pharmacology (medication )
Whats the next video on?
Very helpful, thank you very much