How Do Nitrates Work? (Nitroglycerin)

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  • Опубліковано 29 вер 2024

КОМЕНТАРІ • 102

  • @ronkwarin6917
    @ronkwarin6917 3 роки тому +77

    I think, Nitroglycerin reduce preload which mean reduce venous return to the heart and reducing working load of the heart, reducing oxygen demand in myocardium. Dilation of artery will effect coronary arteries thus increase oxygen supply to myocardium.

    • @ismelzavalagatcia601
      @ismelzavalagatcia601 3 роки тому +1

      En espanol

    • @MoniBrice
      @MoniBrice 2 роки тому +1

      This is beautifully written. Thank you!

    • @sklatif2945
      @sklatif2945 2 роки тому

      Thank you very much for describing in short

    • @bobcocampo
      @bobcocampo 2 роки тому

      Will isosorbide dinitrate be a good supplement to improve nitric oxide?

    • @anjelsgrandpa
      @anjelsgrandpa 2 роки тому

      @@ismelzavalagatcia601 gg th h yu

  • @DrugChug
    @DrugChug  3 роки тому +31

    Thank you so much for the support guys! Glad to see this community growing!
    More videos are being worked on as we speak! 😁

    • @BowgFrowg
      @BowgFrowg 2 роки тому

      Let's do meetups where we take drugs! Together! As a community 🚰

  • @dollychew4064
    @dollychew4064 3 роки тому +22

    I can only appreciate how much effort you have put into helping educate the community and viewers. Thank you so much!

    • @DrugChug
      @DrugChug  3 роки тому +3

      Thank you so much for your support! 😁

    • @bobcocampo
      @bobcocampo 2 роки тому +1

      @@DrugChug
      Can Isosorbode be used as a supplement to improve nitric oxide level in the body?

  • @mr.medtech731
    @mr.medtech731 3 роки тому +11

    Keep making more videos boss. They’re so helpful.

    • @DrugChug
      @DrugChug  3 роки тому +3

      Thank you for watching! More videos are being made!

  • @rasmanyt
    @rasmanyt 3 роки тому +6

    first time watching...to me u are a godsend online doctor...u speak so clearly, right speed and v clear pronunciation...am feeling so happy stumbling upon u today while checking on GTN

  • @rachj1398
    @rachj1398 2 роки тому +4

    Thank you for making these videos. Very informative and helpful

  • @pharmbydas
    @pharmbydas 2 роки тому +3

    my pleasure for your teaching skill thats simple and smart

  • @sunrunnernge560
    @sunrunnernge560 3 роки тому +6

    Bloody brilliant video. As are all your others! The best ones on the internet IMHO

    • @DrugChug
      @DrugChug  3 роки тому +1

      Thank you Sunrunner! 😊

  • @BK-mg4we
    @BK-mg4we 3 роки тому +5

    You explain it so flawlessly!! It’s finally clicking!!!

  • @goddestroyer3416
    @goddestroyer3416 3 роки тому +6

    Very good videos! I'm learning so much, thank you so much, keep them coming.

    • @DrugChug
      @DrugChug  3 роки тому +2

      Thank you for the support! More videos are planned! Stay tuned

  • @sydneyangielli4717
    @sydneyangielli4717 2 роки тому +5

    The best of the best. This should be what every cardiologist should tell their patients to watch as an intro to medications he/she prescribes. Well done!

  • @harrytrev0167
    @harrytrev0167 3 роки тому +6

    Congrats on the 10,000 subs. Great videos!

    • @DrugChug
      @DrugChug  3 роки тому +1

      Thank you so much for the support!

  • @jayibakumarra
    @jayibakumarra 3 роки тому +6

    This was great! I wish every class was taught like this!

  • @rethijja3331
    @rethijja3331 2 роки тому +2

    Omg thanks a lot this is the vedio that I've been looking for!! Amazing work 👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼

  • @croys8608
    @croys8608 Рік тому +2

    Superb quality of information. Thank you. I enjoy pharmacology now!

  • @rightway1625
    @rightway1625 2 роки тому +3

    Really appreciate your hard work and thanks for giving us a mindful lectures

  • @teamgo9980
    @teamgo9980 2 роки тому +2

    Do I need to lock up my nitroglycerin in a cabinet. I’ve been carrying it in my left pocket since I had my heart attack at the age of 36 and I am healthy as a horse when I had my heart attack it was just runs in my family. I have a question and I’m just curious but if you have to take more than Three doses five minutes apart and it hurt you or kill you?

    • @gottabepablo
      @gottabepablo 2 роки тому

      It can potentially lead to hypotension, which can result in a lack of sufficient oxygen delivered to important parts of the body like your brain. Which is no bueno :/

  • @peejread2309
    @peejread2309 3 роки тому +5

    Clear and understandable explanation. Thank you!

    • @DrugChug
      @DrugChug  3 роки тому +2

      Thank you for watching! 😁

  • @nanaperry1066
    @nanaperry1066 3 роки тому +4

    Thanks so much, understanding you is so easy.

    • @DrugChug
      @DrugChug  3 роки тому +1

      Thank so you much for watching, more videos are planned!😄

  • @fluffyrider9467
    @fluffyrider9467 2 роки тому +2

    Thanks I have a Pt teaching assignment and this helped a lot!

  • @eck1438
    @eck1438 2 роки тому +2

    Nice& detailled to ease the subject...i appreciate it..

  • @NeetuKumari-mx3nk
    @NeetuKumari-mx3nk 3 роки тому +3

    Appreciated 🙌🙌 thank yu so muchh ..
    This helped me alottt to understand .

    • @DrugChug
      @DrugChug  3 роки тому +2

      You're welcome 😊

  • @faithosawe338
    @faithosawe338 3 роки тому +2

    Love this teaching like it was very calm so every word was just penetrating . Lovely

  • @MauiXoXo
    @MauiXoXo 2 роки тому +1

    I appreciate the video. I am a visual learner. New subscriber here.

  • @lynvigna4127
    @lynvigna4127 3 роки тому +2

    Thank you so much very helpful!

  • @vanw1504
    @vanw1504 2 роки тому +2

    You are doing a fantastic job! Thorough and straight to the point! Excellent!

  • @rottiesdad
    @rottiesdad Рік тому

    Back in the 80s and 90s I had to walk to my library when I was curious and wanted to learn. Now it's at the touch of a button. Almost all knowledge. So my question is why do I see morons every fucking day EVERYWHERE!?

  • @azadysarchn1659
    @azadysarchn1659 6 місяців тому

    Thank for your explanation of all the drugs I found
    Please if you have any explanation of the role of garlic metabolism and as a drug if we counted like a drug not like a food... it's pharmacology

  • @bobcocampo
    @bobcocampo 2 роки тому +1

    If you don't have angina pectoris can you use Nitroglycerine in low dose as supplement?

    • @teknofreak2387
      @teknofreak2387 Рік тому

      I would not, but i also thought about this🤔it expands the blood vessels so it could be used for lifting (like many bodybuilders use viagra to get more pump), but it also would be interesting how it affects sex. Another angina pectoris medication (Amylnitrite) is widely used as „poppers“ cause sex on it feels awesome. Only downside is that it only lasts about one minute, and that you habe to inhale it. Would be interesting if nitroglycerin has similar effects, at least the side effects named in the Video Sound similar😂

    • @bobcocampo
      @bobcocampo Рік тому

      @@teknofreak2387
      Do you know of any research? Will it help CKD?

    • @teknofreak2387
      @teknofreak2387 Рік тому

      @@bobcocampo i dont know i didnt study Pharmazeutics at an university yet im just a pharmazeutic tecnician😂dont know how you call it in USA. I didnt find any study and dont think they will do ones on th „recreational“ use of this medicine. But self experiments wouldnt be that hard and maybe also fun😂

  • @winghosamLeung-ff3bu
    @winghosamLeung-ff3bu Рік тому

    What is your comment of Nitriglycerine cream use for improvement of ED ??

  • @CraigMullins1
    @CraigMullins1 2 роки тому +1

    Would it be unsafe for anyone to take? Any precautions? I have been having chest pain & headaches ever since covid vaccine and wanted to see if it helps.

    • @gottabepablo
      @gottabepablo 2 роки тому +1

      If you have a history of low blood pressure or take ED medication then it’s not recommended to take Nitro. Aside from the fact that it’s also a medication that must be prescribed. Also a side effect are headaches, it really won’t make those go away. I’d talk to your or a doctor before obtaining and taking it.

  • @nazarhassan5872
    @nazarhassan5872 Місяць тому

    Superb, your explanation is really next level sir.

  • @timthuo2498
    @timthuo2498 15 днів тому

    Thanks man you tutor well

  • @princeabdo5434
    @princeabdo5434 3 роки тому +1

    Keep making videos u will reach a million subs when people find ur channel

    • @DrugChug
      @DrugChug  3 роки тому

      Wow! Thank you for the continued support!

  • @rhodamaliwa770
    @rhodamaliwa770 Рік тому

    Thank you so much for your simplified explanations 🙏🙏🙏🙏
    Am kindly asking if you can make videos on GIT pharmacology drugs 🙏🙏🙏🙏🙏🙏🙏🙏🙏

  • @kimienick6721
    @kimienick6721 2 роки тому

    Its give good return result, but the side effect headache mix with hypertension😑😑😑 can made you struggle for 2 night

  • @Jada452
    @Jada452 2 роки тому

    What will happen if you stop taking your inder?... I for got for a few days or a week idk tbh... but OMG! It felt like I was having a heart attack! Worst trust brain I've ever felt in my life!! and I was Also extremely stressed out stone am lol but the pain is not as bad now no last as long as be for

  • @imadyousufzai2998
    @imadyousufzai2998 4 місяці тому

    Thank you sooo much ❤❤😊

  • @spiritclouddesouza3014
    @spiritclouddesouza3014 2 роки тому +3

    Thank you so much, just started Iso....today, needed to hear this.

  • @bobcocampo
    @bobcocampo 2 роки тому

    How about if you only take 5mg Isordil for prevention? Can you take it every 12hrs?

  • @karinahastika7362
    @karinahastika7362 Рік тому

    came here after watching how Johan Liebert killed 1 director and the other 2 doctor in monster anime 😅

  • @sutenly1
    @sutenly1 7 місяців тому

    Can reduce plague?

  • @raedabuzant7626
    @raedabuzant7626 Рік тому

    Thanks for the great job you did upon this educational video, this was really amazing.

  • @mohmedyzed8920
    @mohmedyzed8920 5 місяців тому

    thnx 4m egypt

  • @sathghuru
    @sathghuru 11 місяців тому

    Very Good Explanation Thanks from India

  • @umm_kulsum1
    @umm_kulsum1 9 місяців тому

    Thank u so much

  • @bobcocampo
    @bobcocampo 2 роки тому

    Can you take isosotbide if you are prediabetic as prevention for heart disease and kidney disease?

  • @Selfbelive636
    @Selfbelive636 7 місяців тому

    b .c .d. d

  • @CynthiaMartinez-qp8gm
    @CynthiaMartinez-qp8gm 8 місяців тому

    Do you have more videos? There’re super helpful.

  • @Selfbelive636
    @Selfbelive636 7 місяців тому

    Thanks❤

  • @drx.monishansari6188
    @drx.monishansari6188 9 місяців тому

    Thank you so much sir this is very helpful to me❤

  • @pengseansem2505
    @pengseansem2505 11 місяців тому

    Great presentation, thank you very much.

  • @jaclynhernandez7547
    @jaclynhernandez7547 Рік тому

    Thanks for the great content. You made it so easy to learn (:

  • @nurseraidarider7140
    @nurseraidarider7140 6 місяців тому

    Thanks a lot, very clear explanation 😊

  • @jonathanvasquez-mv9ic
    @jonathanvasquez-mv9ic Рік тому

    Epipen

  • @thehigherevolutionary
    @thehigherevolutionary 3 роки тому +1

    Dang, I missed the premiere!!!

    • @DrugChug
      @DrugChug  3 роки тому +1

      No you didn't! Haha, sorry I was testing out how to publish the premiere and accidentally just published it 😅

  • @bobcocampo
    @bobcocampo 2 роки тому

    Is there a contraindication of niacin with isosorbide dinitrates?

  • @ahmedthamir9531
    @ahmedthamir9531 Рік тому

    what is the difference if any between mono and dinitrate?

  • @bobcocampo
    @bobcocampo Рік тому

    Any research on the effect of NO with CKD?

  • @frankargenti
    @frankargenti Рік тому

    ja sniffing mononitrate is not the best experience

  • @evelynorta232
    @evelynorta232 3 роки тому

    I have a question, what if you're 18 year old girl with Scleroderma taking Sildenafil for high pulmonary arterial hypertension and also taking nitro bid as well. Is that bad?

    • @ilhamjirde2954
      @ilhamjirde2954 3 роки тому

      Sildenafil and nitrates are both vasodilators, thus their combination can lead to severe hypotension which is bad

  • @ultraplayer2323x3
    @ultraplayer2323x3 2 роки тому

    Thank you for this lecture!

  • @ismaielhassanbara843
    @ismaielhassanbara843 3 місяці тому

    ❤❤❤😊😊😊

  • @iraqi3612
    @iraqi3612 2 роки тому

    that was too useful♥thank you Doctor

  • @sravanip2404
    @sravanip2404 Рік тому

    OMG it was a great explanation ❤

  • @naveena3712
    @naveena3712 3 роки тому

    Where are the answers for ur questions

  • @bellabhat9089
    @bellabhat9089 Рік тому

    👍

  • @bellabhat9089
    @bellabhat9089 Рік тому

    👍

  • @DrRK_HEALTH
    @DrRK_HEALTH Рік тому

    👍

  • @tski3458
    @tski3458 2 роки тому

    Do the headaches ever go away?

  • @chamarimendis5596
    @chamarimendis5596 Рік тому

    Superb. I really helpful.

  • @sufiyashah4694
    @sufiyashah4694 2 роки тому

    amazing bro omg thank u

  • @lahirudissanayaka-mk8sq
    @lahirudissanayaka-mk8sq Рік тому

    superb...❤❤❤

  • @nyawirawaithaka4993
    @nyawirawaithaka4993 3 роки тому

    Thank you!

  • @kimienick6721
    @kimienick6721 Рік тому

    I CANNOT use Isordil and another unstable angina medicine..
    I can use nitroglycerin only 😅 I also have experience use nitroglycerin two pieces tablet in same time and it only used for STRESS TESS or MSCT SCAN treatment... Only me can sweet dreams inside MRI machine 🤣 the rest need monitoring after check up...☺️ But after 3 days I admitted to hospital due WALKING alot after colouring injection into blood.. no option because I ride Commuters 🚈 😅

  • @kohlrabenschwanz
    @kohlrabenschwanz 6 місяців тому

    it "literately" means chest tightness or constriction.... not pain. tf