Intracellular receptor | Nuclear receptor | Nuclear receptor and its mode of action
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- Опубліковано 1 лип 2024
- This video describes the concept of Intracellular receptors & Nuclear receptors. It describes the Nuclear receptor and its mode of action. Overall it describes the signaling mechanism of intracellular receptors and illustrates the molecular mechanism underlying signal transduction.
I watched a couple of other videos about this topic and they were so confusing thank you so much for making yours so clear and easy to understand I really appreciate people like you who make amazing content for free!
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Thank you Arpan. Your video saves us a lot of time while also allowing us to imagine the complex cellular mechanisms.
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I thank you kind sir. You really explained everything clearly and even gave some context insight at the end!
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Awesome ☺️
Thank you so much for this great explanation ✌️
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Excellent explanation! Thank you so much!
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Excellent presentation.
Very well explained, well done
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Thank you very much !
Great video! Thank you!
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मैंने सोचा था कि nuclear receptors से तेज extracellular receptors काम रकते है। जैसे g proteins। शुक्रिया भाई!
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perfect explanation. Thank you
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Best educator on UA-cam
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well explained presentation. Thanks Prof.
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Explanation is very good 💚 thanks
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You explained it so beautifully 🙏
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Thanks!!!! It was helpful for real!
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Superb lecture bhaiya. Can u please make a video on quorum sensing in hindi
Awesome! Make more.
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so helpful ...Thankx😊
nisha soni please share among your friends and help me to reach big audiance
great video!
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I m going to give csir net exam....and this type vdos are very helpful
so please share among friend who has the same goal like you....
Do watch other playlists as well
@@animatedbiologywitharpan thank u
I think estrogens, androgens receptors are found in the nucleus before ligand binding while minerocorticoid and glucocorticoid are in the cytoplasm I think
Nope my friend, In the absence of ligand, the Andogen Receptors / estrogen receptors are cytoplasmic, associated with heat-shock and other chaperone proteins. Androgens bind to the AR, resulting in a conformational change, dissociation of chaperone proteins and exposure of the NLS. The androgen/AR complex translocates to the nucleus where it dimerises and binds to AREs within classical target genes to modulate gene transcription
www.ncbi.nlm.nih.gov/pmc/articles/PMC4810760/ refer to this article for detailed understanding
Thanks for your comment 👍
@@animatedbiologywitharpan ok thanks
Nice to meet u again
It’s an important concept for any exam or in general
Perfect
Great video🙌🏿
Is the vitamin D receptor nuclear or cytoplasmic?
It’s cytoplasmic but it translocate into nucleus
@@animatedbiologywitharpan Thanks a lot. I've always known it to be cytoplasmic, but I saw something contrary on U world.
Thank you so much !
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1. Doesn't RNA polymerase 1 only transcribe the rRNA in eukaryotic cells, most of the transcription is made by RNA polymerase 2 in eukaryotes. 4:52
Correct me if I'm wrong
RNA pol 2 is the key polymerase transcribing mRNA in eukaryotes
Nice
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Again 👍 up
Thanks sir
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I love this
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
Ok
Where is the link for zinc fingers video?
Type dna binding domain in UA-cam and you would find my video
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This is how steroidal agent works
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I burnt out my receptionist. I hope my receptors are ok
Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
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Bro u had made a big mistake the estrogen receptor dimer should bind to the inverted sequence on the opposite strand
It's a basic overview , the sequence and structual details are not considered in this video. It just highlights the point that there is a hormone response element.
There are 2 hours long video which explain half of it.
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Can you explique in french plz
I don't know French 😕
Be more clear dude! This is so clumsy. Anyway appreciate the effort.
I disagree. This presentation was very helpful and intuitive for me. Perhaps give it another watch if it wasn't clear the first time. :)
Stop using fake accent
Thanks for your feedback m..we would try to improve it in the future