Besides the VERY MINOR flaw in remaining zoomed in during a certain segment this was a very succinct and well presented lesson on GPCRs. Thanks for posting it up, it's been a great overview to revising the key concepts.
This was perfect! The only thing this video missed was that after ATP is converted to CAMP, CAMP then goes on to activate Protein Kinase A to THEN produce the physiological effects.
Great clear explanation. I studied this back in undergrad and want to carry out an experiment now in my PhD where I inhibit G-alphaS and see downstream function. I need a quick re-fresher and this hit the spot! Thanks!
Thank you so much. I went through my lecture slides, recording but still not understanding a piece of information like you did in 12 minutes. I am so grateful to be here with other students.
How hours of boring lectures are made into a 12 min riveting knowledge is always going to be a mystery to me #Khanacademy. Thank You for saving my life btw
Lol did a cat jump on your notes @7:45? 😂 Awesome, clear, accurate, and well explained video btw. The zooming-in issue wasn't very hindering in terms of understanding the concept, but it would be that much better if it was fixed. 9/10
Wow , very well explained 👏👏 i always get scared when i hear g protein coupled receptors (sounds scary right) but now that ive tried to understand its so simple thanks khan academy
Greetings from Sweden! Thanks for a great video! Dont know if it really matters, but it's an adenylyl cyclase (not adenylate) according to my biochemistry book.
Both terms are used. I just checked two of my danish textbooks. Biochem-book says 'adenylate' and Pharma-book says 'adenylyl'. But I also seem to recall that previous english textbooks I've read uses 'adenylate'. I guess it's just a 'cultural' thing, regarding what system you use to name the functional groups.
Both terms are used, adenylyl is kind of an old fashioned name, some of the pictures of researches my lecturer shown us use adenylyl, but adenylate is used in most universities in London as as far as I know.
I'm overwhelmed with joy, I finally passed my NCLEX RN after three trials and I almost gave up until I met this God sent. Please join me celebrate my helper Dr Brooks for his consistent assistance showed to me during my preparations for this exam. If you want nclex to be history to you, contact Dr Brooks via text or whatsapp on +12404085402.
This guy taught me better in 12 minutes than my professor did in a 45 min class. Kudos dude.
and my one took more than an hour.
@@naveedkhankakar144 and mine took more than five hours 😫.
Hahahhaha we are in same category
@@fizazainab1526 hahahaha yup we are.
@@naveedkhankakar144 good luck for your future
Besides the VERY MINOR flaw in remaining zoomed in during a certain segment this was a very succinct and well presented lesson on GPCRs. Thanks for posting it up, it's been a great overview to revising the key concepts.
I HAVE SPENT 2 YEARS IN MED SCHOOL MANEUVERING MY WAY THROUGH COUJTLESS EXAMS AND VIVAS WITHOUT EVER REALLY UNDERSTANDING THIS! UNTIL TODAY! THANK YOU
this is me right now haha
thats kinda sad
Did you graduate yet? If so, congratz!
How far
I need a mentor. I just got into my first year of medical school
why did the video zoom in so much i can't see~~!!
This was perfect! The only thing this video missed was that after ATP is converted to CAMP, CAMP then goes on to activate Protein Kinase A to THEN produce the physiological effects.
Thank you for your contribution
to talk about this would be a specific video about the second messengers
Bruh, it's been 9 years, this video needs a re-edit for those precious minutes gone while it was zoomed in
Except for the zooming error, this video was a spot on. Thank you. I heard that it was called "adenylyl cyclase" though.
+Jai A Meyrick Thanks. I'll have to remember that.
Daniel Bundrick g
Adenylate cyclase
It does the same thing ,but it’s an amplifier enzyme so I think there must be a difference
Adenylate cyclase, adenyl cyclase, & adenylyl cyclase are all the same enzyme. Confusing redundant names, that's science.
Great video! FYI the zoom only lasts for like 30 seconds yall ;)
more like 1 -minute......
It goes from 4:03 to 5:23 for a total of 1:20 or 1 minute and 20 seconds, plus or minus a few seconds.
well with subject like this, every second is crucial, the dude fucked me up
This is the best video explaining GPCRs out there. Tysm
This video helped the concept of G proteins finally click in my brain. Thank you!
Jocelyn Justice go for The Great Dr.Najeeb if you really want to build your concept
Thank you sir, it helps me a lot for my final exam
I like the way you explain this 5-full-pages theory in a simple way. Thank you! This helps me for my tomorrow exam ehehehe
This guy taught me better in 12 minutes than my lecturer did in a 2 hour class. Levels, thanks dude.
Or maybe you don’t pay attention😊
Great clear explanation. I studied this back in undergrad and want to carry out an experiment now in my PhD where I inhibit G-alphaS and see downstream function. I need a quick re-fresher and this hit the spot! Thanks!
I tell you am wid u on this one same here am good to go now😅
Thank you so much. I went through my lecture slides, recording but still not understanding a piece of information like you did in 12 minutes. I am so grateful to be here with other students.
Same here, the lecture and audio from my boring lecturer was always inducing sleep
How hours of boring lectures are made into a 12 min riveting knowledge is always going to be a mystery to me #Khanacademy.
Thank You for saving my life btw
Please fix the zooming issue!
You have to change it to full screen, it worked for me :)
@@oxysmoxy1977 doesn't work
Greatest video ever. loved it. Thank you for being alive.
This video saves my 1st year as a medical student!!!!! Thank you so much!!!!!
MY PROFESSORS COULD NEVERRR. THANK YOUU 🥹🫶🏼
What would I do without Khanacademy?? Great explanation, as always😁👌🏼
5:23 continued from zoom out
Amazing I love it ❤❤❤
Your speech was so clean that despite my poor english i could have understood you well. thank you :)
Thank you for the simplest , you explain better than my professors at the collage and for free
for the first time iunderstand the concept of GPCRs. Thank you
This helps us so much even if it was made 8 yrs ago
Lol did a cat jump on your notes @7:45? 😂 Awesome, clear, accurate, and well explained video btw. The zooming-in issue wasn't very hindering in terms of understanding the concept, but it would be that much better if it was fixed. 9/10
Brilliant. Really helpful.! Thanks a lot
please help me with the kind of textbook
that you guys use
its really very well understood
Very helpful! Thank you. The visual really helped.
EXACTLY what i was looking for!! thank you!!
Thank you, i finally understood this!
So good. Worth my time
Made this sooo much easier to understand!
Any thoughts on fixing this video? It is a wonderful explanation worthy of an unspoiled presentation in true KA style.
Excellent explanation!! Thank you
great job . thanks from Syria
Wow this is SO helpful!!!!! Thank you
wow. so nice. however i haven't understood the connection between the heterotrimeric complexes and the GPCR. Would you explain please? thank you
Finally got the concept of g protein ,thanku for this work 👍
tHIS MAKES SO MUCH SENSE
Omg! I love this channel
You have just activated my G-Protein awsm Khan Academy Simple Smart and Conceptual what else do we need
Wish harper's was easily understood as this........
This is a savior 👏
thank you so much, i learned more from this video than i did in a 2 hour college lecture..
Super helpful video!
Thank god for Khan Academy
i couldnt get the topic on my lecture but now it is all clear! thanks a lot! Thumbs up :)
Thank you :) You've made final year physiology a little easier.
what! you were whatching this on your final year?
we read this on first year
Thank you so much for this!
Informative video... thnx a lot
Wow , very well explained 👏👏 i always get scared when i hear g protein coupled receptors (sounds scary right) but now that ive tried to understand its so simple thanks khan academy
wtf man
Cabero lol whatcha sayin‘
This kind of videos doesn't even deserve 1 dislike ❤️❤️
Woow thank u so much, u explained such a hard tissue sooo easily and clearrrr, ur greattt
What an excellent explanation
WONDERFUL!!! I learned more from this video than my 3-hour-long graduate class!!! THANK YOU VERY MUCH!!!
Way of teaching adorable...
Greetings from Sweden! Thanks for a great video! Dont know if it really matters, but it's an adenylyl cyclase (not adenylate) according to my biochemistry book.
Both terms are used. I just checked two of my danish textbooks. Biochem-book says 'adenylate' and Pharma-book says 'adenylyl'. But I also seem to recall that previous english textbooks I've read uses 'adenylate'. I guess it's just a 'cultural' thing, regarding what system you use to name the functional groups.
Both terms are used, adenylyl is kind of an old fashioned name, some of the pictures of researches my lecturer shown us use adenylyl, but adenylate is used in most universities in London as as far as I know.
they use both here at the University of Otago :)
I’m so thankful ❤️❤️❤️❤️❤️ for this video
I'm overwhelmed with joy, I finally passed my NCLEX RN after three trials and I almost gave up until I met this God sent. Please join me celebrate my helper Dr Brooks for his consistent assistance showed to me during my preparations for this exam. If you want nclex to be history to you, contact Dr Brooks via text or whatsapp on +12404085402.
This video was amazing.
Thank you! Good video
Thnx for the explaination 👍
Thank you very much that’s help me more 🙌❤
Great video ... Alpha-Omega
Helped me through my exams!! Thanks!!
excellent presentation. perfect. thanks from Greec
Great video! Thanks so much!
That was a very useful and helpful video
Very well explained!
Wow that was great!
Thank you so much I am forever grateful.
Thank you😭😭😭
Want to like this video 10 million times
Amazing video ❤
Does the GTP replace the GDP? Or does a phosphate bind to the already-bound GDP creating GTP on the alpha subunit?
You are awesome! thank you so much!!
The zoom problem doesn't last long and you can see what happened shortly after it is corrected. Be patient. You'll get it!
Wonderful and clear! Thank you!
very nice presentation...
Really helpful 💕
Great Video! Thank You
Thank God for you
Nice explanation
Thank you soo much for this video man....
Thank u so much it was soooooo useful ♥️
This video is my lifesaver. Thank you so much!
Thank you so much for this. Really clear and helpful. God bless you❤❤❤❤❤❤❤
Thanks. I like your hand writing
very good video, thank you very much!
Awesome video sir 😍😍😘😘👌👌👌tx sir🙏🙏
Excellent 👏
Good video.
Killed it.
thank u so so much. This video is very great!
It is very good explanation.
Thank you. Absolutely amazing! :)
Great video; liked it. But question, can you call the beta & gamma subunits a dimer if they are not identical molecules?
thanku for teaching,its awosome....
Thank you sir 😇🙏🏻