I'm back! Been a busy few weeks for me, but so pleased to take another look at Cells at Work! Hope you enjoy... Anyone wondering about the hair curl I have throughout the video, it's a homage to Red Blood Cell and not a grooming malfunction :)
Dr Hope's Sick Notes Someday, you should watch Black Jack. its a 60s medical drama manga and anime by Osamu Tezuka, who's basically the father of that medium.
I cackled at how you delivered, "Awww... the poor pollen! He's very harmless, he's just a lost male sex cell in a protective layer, trying to find a female flower to germinate. But, he's just looking in all the wrong places!" (I'm really enjoying this series from you!)
Cut us some slack, we can't know everything xD. Our brains are for thinking, not so much for remembering stuff anyways so don't get nervous when your doctor pulls out a spreadsheet or something similar (It is likely more accurate and up to date aswell).
@@Smokecall Publicly modifiable, sure, but IBM researchers reported that "vandalism is usually repaired extremely quickly-so quickly that most users will never see its effects"
yea now imagine your doctor tells you to hold on a moment he remembers there was an episode on that topic in an anime show you just need to quickly rewatch it to know how to deal with it xD I would probably burst out laughing my ass off dying happy xD sadly doctors in germany are generally old farts who would never agree to watch like cells at work unlike Dr.Hope does or they dont speak german very well... Would be awesome to be one of Dr. Hopes patients, probably
@Samuel A. Lim Are you certain that the story suffers with the addition of a mech with a minigun? i think it would be bloody awesome if Harry Potter was an anndroid created to hunt voldemort down. but whatever, i guess...
I would've loved to see the cedar pollen just wandering around the place looking confused, like a big dumb marshmallow who was just blown in out of nowhere, while the immune system went absolutely nuts around it, attacking it in a panic, damaging the body in it's attempt to keep it safe
I actually moved to Japan a little over a year ago and the typical medications people use can be a bit different from the western world. In terms of pollen allergies, people don't typically take antihistamines, and instead wear surgical masks to limit the amount of antigens entering their bodies. People where I live only typically take medicine when the symptoms are especially bad, and rather than histamines it would be steroids. This might help explain why the show went the steroid route rather than the antihistamine route for the episode.
On that note, an old surgeon in my med school who traveled the world also noted that different population in the world has vastly different sensitivity and reaction to anesthetic agents. Interesting stuff.
I mean its a japanese anime so it makes sense that they orientate on more common things there (like with the sea water/food stuff in the last episode in combination with raw fish)
@@chunt5584 That makes sense - Isolated populations (even if not nearly as much as they used to be) tend to share similiar traits, including suseptability to certain sicknesses. And since Alergies are usually not leathal, they're not stopping the person from passing it on.
it also explains why the plant pollen is from cedar trees and not, like, ragweed or grasses, which is what's common in america. i was also really surprised about how cells at work chose to use steroids, because americans tend to see steroids as a big boy drug that's really only used when otc options don't work
"This wouldn't really happen in real life" What, do you mean I don't have little red-wearing anime girls running around my blood delivering boxes and all-white guys with knives hunting rogue bacteria?
I'm japanese high school student. Thanks to this video, I can understand about working cells. I'm sorry about my bad English but I wanted to tell you Thanks.
In Japan, after the war, we actively planted trees to meet the increasing demand for timber, but we still have many left over because we chose cedar trees that grew fast at the time. There are still many people with hay fever. In Japan, 1 in 3 people suffer from cedar pollen. I am also troubled by pollen other than cedar trees. I'm sorry if my English didn't' make sense.
Literally the only error you currently have is an erroneous apostrophe; you've got a level of English comprehension that I would associate with those that use their second language as a major component of their job. That's fluency nearly on par with native speakers, and the only reason I say "nearly" is because the structure is a bit strange- certainly nothing that could be considered incorrect, just not perfectly natural. You're doing a fantastic job and you'll only continue to get better, but I consider this mastery already.
I'm a non-native English speaker and not even a medical student, yet I enjoy your reaction to cells at work all the same, fun and educational. Great job!
"The tea getting spilled- that's a very English problem we can relate to that" 😂😂😂 I love your reactions/commentaries Not only educational but also funny haha
''He's very harmless, he's just a lost male sex cell in a protective layer, trying to find a female flower to germinate. But, he's just looking in all the wrong places'' Me if I was a male
As a scientist, myself, I absolutely loved the series and their take on the intra/intercellular communications and how everything worked out, finally even bringing up phagocytosis, showing the ridiculous overreaction, showing how useless eosinophylls would be toward bacterium, while being a powerhouse against parasites, and the adorable platelets... And Dr. Hope's take on this all did excellent in breaking down the highly complex situations and comparisons and simplifying it, further-explaining what the show only touches on in a more technical sense. It's actually pretty funny; because, I'm literally going through a good number of these situations (Outside, of course, of the parasite and the food poisoning). It's nice to see how the anime heroes in my body are combating the illness and allergic reactions I'm currently facing, as well as how the steroid I just had to take unleashed a damn robot to wreck the membranes of my body's cells.
A slight character detail he didn't show, is that WBC was actually sad about killing the cedar pollen, but needing it to be dispatched hence why he paid respects to it when it died, which will be an character trait for an important episode later on.
The machine gun / gatling gun might reffer to suppression of Imune system by steroid In military automatic weapon commonly used to deliver supresing fire to pin down enemy
@@DrHopeSickNotes The T Cell brigade we see actually have a memory cell, he has a filder with hearts on it. You can see him in the T Cell explanation in the influenza episode. Im pretty sure that he is in that freeze fame, I know for sure that he is in that episode.
I loved Ed talking about the different reactions to medical emergencies! JUNIOR: The patient is vomiting blood! SENIOR: Not good. JUNIOR: The abdomen has opened and I can see the bowels!! SENIOR: I see. Anything else? JUNIOR: The patient is on fire!!! SENIOR: Hmm. I might be able to get a paper out of this....
Once again another thing i missed from this show! I've always wondered why B cell's gun is the way it is... I should've known! XD awesome job by the creators of the show
Antibodies be like the Fan o War Thats how i remember :P Also, Ive studied a bit of immunology decided to take a look. Although it seems correct on most scales, its anime, so you have the casual exageration and cringe IgE is the bane of my existence
Just a little side note: the Memory Cell in this episode isn't a T Cell. He's a Memory B Cell. In the show, he's shown running a library filled with information about previous infections, which B Cell uses to make his antibodies.
Tria Maxwell no there IS a memory T Cell appearing in the Influenza episode. He does look like the black uniform-ed military guys (like the Killer T cells does) but his hat says “MEMORY” (not the usual “KILLER”) and he brought a pink heart patterned notebook.
Interviewer: This job requires you to have a PhD in Human Microbiology. Me: Not to worry. I've watched all episodes of Cells at Work. Interviewer: OH S**T YOU HIRED!!!
The way I see all the destruction and mayhem seemingly being caused by the pollen is how the cells perceive the 'invasion.' In that one scene you showed, it seemed like the panicking cells knocked into the pollen, *pushing* it into the building. So it was still the cells over-reacting that caused the damage and misapplying blame.
This is so much better than other non-content based reaction videos. Love the way you stop things and then use visual effects and analogies to make the learning fun. Very professional and inviting. Also, kind of apropriate the cat muked up your cell a bit since cats can carry a lot of pollen in their fur and often cause allergies themselves.
I really like that the steroid didn't actually kill the cells, but it scared the heck out of the mast cell and B-lymphocyte which suppressed their activity. The level of detail this show works on sometimes feels like Easter eggs. Your input is a fantastic addition to this really fun bit of education (supplement?). I've suggested this show and your reaction series to my microbiology professor for his intro to microbio course.
Bursa of Fabricius is involved in B cell development in birds! Even as a vet student, I loved the show and I thoroughly enjoy your explanations throughout the video. Looking forward to your future videos!
The Memory cell shown here is actually a Memory B cell, it's more explicit in the manga, showing how they share an office space and work on problems together. A memory T cell shows up later on when the main Killer T cell becomes one. PS I love how you stop to visually explain the real science behind what is happening in the show!
"Tea being spilled, that's a very English problem, I can relate to that." As a American, and a citizen of Boston, Massachusetts.... [[[[[[[[[[[PATRIOTIC FREEDOM INTENSIFIES]]]]]]]]]]
Cancer might be my favorite character in the whole show/manga, besides our main white blood cell himself. ...Which sounds really weird out of context lol
I'm really enjoying this ongoing reaction series. Definitely keep it up. "Steroid Terminator" may be my new favorite phrase. Side-note: The "Helper T Commander" cell is unexpectedly attractive.
... He is... So is the White cell.... We have reached a point in humanity where we find body cells attractive (I know they're kind of represented like people but still), I-
A wild Cells at Work! review appeared! 😮 I actually wondered what happened, not seeing ANY Sicknotes video for the past 3 weeks. Last time I saw something Cells at Work! related was in an Instagram snippet in the 86th Floor Cosplay where a certain doctor is wearing a cartoonish cosplay of a bacteria. 😂 Nice to see you still continuing the series...#6 is an episode with chock full of information to discuss too. P.S. Cells at Work! will air a winter special around December 26 and I think it may be aired on Crunchyroll, so if you can make a review close to that time, it would be great, seeing it would just be fresh.
My cat leaves muddy pawprints because she hops in the bathtub and laps puddles from the most recent shower. -_- I don't understand her. She has two water bowls and they're both clean.
Super Doctor K (manga) and Kusuriya no Hitorigoto (light novel and manga, it has more about old herbal medicine), and then pharmacy of another world (light novel and manga most of the time diagnosis and medicine creation and also the running of pharmaceutical industry)
never clicked a video so dam fast, I might have caused some of my red blood cells on my index finger to wonder what the hell was the "earthquake" about.
I remember when I saw the episode I was so confused but then I realized what the steroid was doing wasn't killing tissue which is what the buildings are but it was leveling the town. Earlier in the episode, in a very brief moment, the cells were screaming that the town was rising and getting pushed up because it was swelling.
(Anime Release! Phoenix Wrightu no Jutsu!) *Slams Desk* What if the reason there were paw prints found on the picture which were confirmed to be of the defendant's cat was because it was the cat's picture all along, and his paw prints were his signature of the painting! ...GUILTY!
Love the show, and love your explanations. While the show does a fantastic job, it’s great to actually discuss how it relates to real life. Please continue to review the show Doctor!
Apart from the amazing content and beautiful graphics of the anime, can we take a moment to appreciate those who create the subtitles~ the anime is so medical info-packed and as a translator/interpreter, medicine is such an intimidating field that I tend to stay away from 😂😂😂😂😂😂 the translator(s) of this anime really did a great job~
I find it more enjoyable to watch doctors reacting to Cells at work rather than just me watching the anime and then having to google from time to time 😅😅😅
The allergy episode was one of my favorite from this show. I suffer from seasonal allergy so I can relate to it. I must say though, Im currently taking an Anthropology class on Human Variation and we are discussing the Immune System and Cells at Work has helped me out so much because thanks to it I feel more prepared on this subject. Then with Dr. Hope's input it helps ingrain the info better. I really like the small drawing/cut-outs of the cells Dr. Hope uses to explain as it makes it easy to digest the info. Im a very visual learner so you have no idea Dr. Hope how helpful these videos are for me 😁👍🏻
I don't think Memory Cell is part of the T group. Kinda more like he's part of the B group. In the opening theme of the show, we see Memory Cell and B cell are together (go away, fujoshis. this for the sake of human anatomy I'm talking here) Which means, he's a Memory B Cell, but not a Memory T Cell
I am a medical laboratory science student and watching "cells at work"+you(doctor) expanding the topic, helps me prepare for my upcoming exam in immunology & serology. Haha thank you Dr!
I had a hive (urticaria) breakout one time and the way the episode demonstrates medication use for mild to severe allergies (such as hydrocortisone or a higher potency such as methylprednisolone) makes me feel a bit bad for my own cells in my body. Really important to stay hydrated and relaxed too. ;)
To be fair the representation of a steroid like hydrocortisone was a bit exaggerated in this episode, as well. But it fit a theme of over-exaggeration being the problem. A cool thing with the show, though, is you never hear about the body but if they're getting steroids for a standard pollen reaction, they must have had a very severe reaction and possibly even ended up in the hospital. Otherwise much less potent medicine would have been fine. Dr.Hope explains a steroid better than I could, but they don't cause as much collateral damage as represented in the anime.
I started watching Cells at Work with my daughter, and after we watch every episode, I come to your channel to get some extra depth explained about what's happening. I really enjoy your content, and after we finish Cells at Work, I'm gonna stay subscribed and check out your other work. Good stuff!
Is it 12:30am where I live? yes. Do I plan to watch all 20 minutes of Dr. Hope geeking out and teaching me more about anatomy and physiology than I ever planned on learning? Also yes. P.S Was totally worth it, but now I really need to get to bed lol. Darn you Dr. Hope for your amusing and informative content! -shakes fist-
I can't even finish the anime until he makes a video about the episode so that I fully understand what happened, lol. Well worth the wait though and about the only time I'm like BUT EDUCATION I need to know!
Thanks for reviewing this episode! As a sufferer of allergic rhinitis for more than a decade, it really made me feel better. Antihistamines are my saviors but yknow, they make me sleepy. It sucks having allergic rhinitis bec it's difficult to do things such as touching dusty things, hugging teddy bears, too much face powder, perfumes, and other things. I love how this episode covers the whole process for the non-medical people to learn. Very educational!
Yay! New episode. Thank you for these! I'm currently in Alaska still recovering from the recent earthquake, and this is really helping my morale stay up. Perfect timing
clericneokun 'advise' is used in caution: such as: "advise me, sir." 'advice' is the correct word you're trying to spell: "what's your advice?" referring to giving beforehand information. it may not seem to have a difference, but there IS. *_LOL_* *_Future Teachers At Work_*
6:25 - the pollen does not cause damage, but maybe some cell saw it and did a damage report just in case ("well, it has not damaged anything yet, but I'm sure it will, better call the police/immune cells anyway", "HELP, the pollen is killing everything its path!") and then the immune cells overreact causing the allergic reaction.
I'm back! Been a busy few weeks for me, but so pleased to take another look at Cells at Work! Hope you enjoy... Anyone wondering about the hair curl I have throughout the video, it's a homage to Red Blood Cell and not a grooming malfunction :)
Cool
Dr Hope's Sick Notes Someday, you should watch Black Jack. its a 60s medical drama manga and anime by Osamu Tezuka, who's basically the father of that medium.
My goodness, so happy to see this new reaction video of yours🤗. Been waiting for so long.
Look at the Gun of B-Cell, it looks like the Protein
First elon musk, a genius billionaire, and now an Doctor.... Soon... Anime shall conquer the hearts of all!!! 😂😂😂
"He's just a lost male sex cell in a protective layer trying to find a female flower to germinate." Aren't we all mate. Aren't we all.
And just like the lot of us...looking in all the wrong places.
@@madpinoy5683, EclairPerversePastry I don't know you or your stories. But for these comments alone, I Love both of you!
Damn, that's deep.
Please don't 😢
I don't know why but this comment got me
It’s nice to know that all of my allergies are caused by my body being just as much of a drama queen as I am
E
Iconic hhhhh
@@Birdman15780 to
this made me laugh out loud
Same bruh xD
I cackled at how you delivered, "Awww... the poor pollen! He's very harmless, he's just a lost male sex cell in a protective layer, trying to find a female flower to germinate. But, he's just looking in all the wrong places!"
(I'm really enjoying this series from you!)
S. Holloway hmm
Better love story then twilight.
So humble~
Better love story than Boku no Pico
Spirit Resonance That was a love story?
That moment when your doctor goes "Hold on, let me Wikipedia that"
Cut us some slack, we can't know everything xD. Our brains are for thinking, not so much for remembering stuff anyways so don't get nervous when your doctor pulls out a spreadsheet or something similar (It is likely more accurate and up to date aswell).
@@SlimTony the spreadsheet and other verified information is fine. When it's a publically modifiable resource it gets a little iffy.
@@Smokecall
Publicly modifiable, sure, but IBM researchers reported that "vandalism is usually repaired extremely quickly-so quickly that most users will never see its effects"
@@valnimationid1371 that's completely fair
yea now imagine your doctor tells you to hold on a moment he remembers there was an episode on that topic in an anime show you just need to quickly rewatch it to know how to deal with it xD I would probably burst out laughing my ass off dying happy xD
sadly doctors in germany are generally old farts who would never agree to watch like cells at work unlike Dr.Hope does or they dont speak german very well...
Would be awesome to be one of Dr. Hopes patients, probably
Mom: anime isnt educational
Red Blood Cell: hold my oxygen
You mean O2.
Erzio • it’s not, i bet ur in 5th grade
Yo mean co2
@@xvaclty7048 it's not Co2
@@xvaclty7048 I believe that's Carbon Dioxide
"Every story benefits from a terminator with a mini-gun", so true.
@Samuel A. Lim Are you certain that the story suffers with the addition of a mech with a minigun? i think it would be bloody awesome if Harry Potter was an anndroid created to hunt voldemort down. but whatever, i guess...
Demonminer sleeping beauty doesn’t eat an apple she gets shot by the terminator endoskeleton
Sam Lim red riding hood would be so much better with a massive gun
Un Limon **coughRWBYcough**
I would've loved to see the cedar pollen just wandering around the place looking confused, like a big dumb marshmallow who was just blown in out of nowhere, while the immune system went absolutely nuts around it, attacking it in a panic, damaging the body in it's attempt to keep it safe
Bryn Jackson
Oh, that would have been so good!
That's kinda what happened here, since they aren't even attacking but just looking around
Pollen: “Ccceeeeddaaarrr????”
Everyone else: “aaaAAAAAAAHHHHHHHHHHHHHHHHH”
POOR POLLEN THEY'RE SO CUTE :"
@@chadmulyadi5025 well as cute as sperm can be, I suppose
I actually moved to Japan a little over a year ago and the typical medications people use can be a bit different from the western world.
In terms of pollen allergies, people don't typically take antihistamines, and instead wear surgical masks to limit the amount of antigens entering their bodies. People where I live only typically take medicine when the symptoms are especially bad, and rather than histamines it would be steroids. This might help explain why the show went the steroid route rather than the antihistamine route for the episode.
On that note, an old surgeon in my med school who traveled the world also noted that different population in the world has vastly different sensitivity and reaction to anesthetic agents. Interesting stuff.
I mean its a japanese anime so it makes sense that they orientate on more common things there (like with the sea water/food stuff in the last episode in combination with raw fish)
@@chunt5584 That makes sense - Isolated populations (even if not nearly as much as they used to be) tend to share similiar traits, including suseptability to certain sicknesses. And since Alergies are usually not leathal, they're not stopping the person from passing it on.
it also explains why the plant pollen is from cedar trees and not, like, ragweed or grasses, which is what's common in america. i was also really surprised about how cells at work chose to use steroids, because americans tend to see steroids as a big boy drug that's really only used when otc options don't work
Well that explains a lot. I was seriously nitpicky about the whole steroid thing.
"This wouldn't really happen in real life"
What, do you mean I don't have little red-wearing anime girls running around my blood delivering boxes and all-white guys with knives hunting rogue bacteria?
Lloooollllllll XXDDDD
This happens in my body all the time
I believe, Socrates theorized you can't _know_ anything. So I would say it is rather unlikely, *but*
Well... Let us just say, fingers crossed, eh?
no but in fact what we have is even more sophisticated, delicate and badass
If not... Then what is the point of living?
the memory cell has PTSD
DONT NOBODY TOUCH THE LIKE BUTTON
@@hopesy12u4 ... I just did.
Uh
Uh
I
I don't know how to respond to that
No. Please don't do that.
Too bad I already did it.
Terminator-steroid doesn't care who's fault it is. Terminator-steroid just wants the body to just chill out for a while
So.... Terminator-steroid is a mom?
@@TriaMaxwell I mean, if your B-cell son and Mast-cell daughter were destroying the house fighting, wouldn't you just ground them both?
@@wessltov Hey, B cell started the fire, Mast cell just tried to put it out
If this is ever dubbed they need an Ahnold soundalike for the steroid Terminator
Tria Maxwell
we didn’t start the fire
It was always burning science the worlds been turning
I'm glad this Series is back. I really like your feedback and take on this show!
So am I. Support this series!
We all do
Thank you for the ♥️, Doc
Hope it ends before Article 13. Otherwise, these series will never end... :(
sameee
I'm japanese high school student. Thanks to this video, I can understand about working cells. I'm sorry about my bad English but I wanted to tell you Thanks.
Your english was pretty good here, don't worry.
Not bad English! Do you know the Japanese already make Japanese subtitle on this reaction video?
You are good, keep it up
Thanks!
Yes! I saw translated video at first.
Your english is fine
In Japan, after the war, we actively planted trees to meet the increasing demand for timber, but we still have many left over because we chose cedar trees that grew fast at the time. There are still many people with hay fever. In Japan, 1 in 3 people suffer from cedar pollen. I am also troubled by pollen other than cedar trees. I'm sorry if my English didn't' make sense.
Hey, your english is good! Omedetou!
Literally the only error you currently have is an erroneous apostrophe; you've got a level of English comprehension that I would associate with those that use their second language as a major component of their job. That's fluency nearly on par with native speakers, and the only reason I say "nearly" is because the structure is a bit strange- certainly nothing that could be considered incorrect, just not perfectly natural. You're doing a fantastic job and you'll only continue to get better, but I consider this mastery already.
Its ok :3 as my mother says, as long as people understand you who cares about grammar.
Thank you for your feedback regarding the cedar pollen! Not only do I learn science here, I also learn a little bit about Japan
Your English is great
The voice actor of Cedar pollen is Tessho Genda.
He also plays Arnold Schwarzenegger of Japanese version.
And Optimus Prime
Now I want to see the scenes with the pollen allergy but with Optimus voice clips
Cedar Pollen: "I'll be back!"
"Every story benefits from a terminator with a minigun" XD
I'm a non-native English speaker and not even a medical student, yet I enjoy your reaction to cells at work all the same, fun and educational. Great job!
chrisroserva me too
x3
Basically me also
Me too!!!
We're six now
The design of those cedar pollen molecules are actually pretty cute, tbh...
right??? I've wanted a plushie of them ever since I saw them in the manga for the first time
They remain me of them candy thing called Peeper if am sleeping them right.
Pray and hope someone makes a merch of cedar pollens
A cedar pollen plushie with actual cedar pollen inside...
@@OverseerMoti are you trying to cause B Cell and Mast Cell to argue?
"The tea getting spilled- that's a very English problem we can relate to that" 😂😂😂 I love your reactions/commentaries
Not only educational but also funny haha
Ha- *starts choking*
ste 'roid'
roid->robot
crazy machine gun which kills everything.
Nice play on words :)
a roid being on roidrage = cool
ain't japanese anime if there's no wordplay! XD
It's a nice point of view.
Well you realize you have to show us your cat now, right?
Duh! Basic internet laws and all!
Here she is:
instagram.com/p/Bq1uwGsBz1Z/
Floof
@@DrHopeSickNotes so fluffy like my pillow
@@DrHopeSickNotes I also have a black and white cat, although he is male and indoor only.
Do you think they made the medicine a robot because it's a chemical rather then a living cell?
I thought the same thing! It's an artificial machine made to mimic a living cell: a robot!
Aye. An artificial synthetic chemical, which is kinda indiscriminate overkill. It doesn't really have a specific target.
Also a nice wordplay. Since the medicine taken is SteROID. Like an Android.
I always thought of viruses as sort of organic robots. Unliving, though they are made of some of the same substances as living beings.
dplocksmith91 that’s why the viruses are depicted as zombies. They are organic, but not living
your cats little pawprints on the bacteria drawing was absolutely crucial to my enjoyment of this video
That's how you kill a bacterium. By letting your cat boop on it.
Totes man crush when he said he had a cat!!
''He's very harmless, he's just a lost male sex cell in a protective layer, trying to find a female flower to germinate. But, he's just looking in all the wrong places'' Me if I was a male
Satan is female confirmed
And they thought god was a woman
@@0AngelOnTheDanceFloor0 Anime seems to think so
@@0AngelOnTheDanceFloor0 I understand that reference!
the way you phrased that implies that you are not a male, but that you ARE a cedar pollen.
As a scientist, myself, I absolutely loved the series and their take on the intra/intercellular communications and how everything worked out, finally even bringing up phagocytosis, showing the ridiculous overreaction, showing how useless eosinophylls would be toward bacterium, while being a powerhouse against parasites, and the adorable platelets... And Dr. Hope's take on this all did excellent in breaking down the highly complex situations and comparisons and simplifying it, further-explaining what the show only touches on in a more technical sense.
It's actually pretty funny; because, I'm literally going through a good number of these situations (Outside, of course, of the parasite and the food poisoning). It's nice to see how the anime heroes in my body are combating the illness and allergic reactions I'm currently facing, as well as how the steroid I just had to take unleashed a damn robot to wreck the membranes of my body's cells.
A slight character detail he didn't show, is that WBC was actually sad about killing the cedar pollen, but needing it to be dispatched hence why he paid respects to it when it died, which will be an character trait for an important episode later on.
I am absolutely in love with that WBC
"Just wear sunglasses, they make you look cool" 🕶
"If I look cool I can avoid my blood being shot at by the Terminator."
"Oh...... Okay then...."
Medical and fashion channel at the same time
The machine gun / gatling gun might reffer to suppression of Imune system by steroid
In military automatic weapon commonly used to deliver supresing fire to pin down enemy
Like this!
@@DrHopeSickNotes The T Cell brigade we see actually have a memory cell, he has a filder with hearts on it. You can see him in the T Cell explanation in the influenza episode. Im pretty sure that he is in that freeze fame, I know for sure that he is in that episode.
I loved Ed talking about the different reactions to medical emergencies!
JUNIOR: The patient is vomiting blood!
SENIOR: Not good.
JUNIOR: The abdomen has opened and I can see the bowels!!
SENIOR: I see. Anything else?
JUNIOR: The patient is on fire!!!
SENIOR: Hmm. I might be able to get a paper out of this....
This helped me realize that when my allergies act up that it's just my body over reacting to dust and pollen.
The B Cell’s gun is Y shaped. Very nice illustration
Jasper Siron When he showed the real form of B Cell i thought the same!
This anime is so creative 💜
Once again another thing i missed from this show! I've always wondered why B cell's gun is the way it is... I should've known! XD awesome job by the creators of the show
The "Y" shaped gun is B Cell's Antibody Gun that releases IgE
Antibodies be like the Fan o War
Thats how i remember :P
Also, Ive studied a bit of immunology decided to take a look. Although it seems correct on most scales, its anime, so you have the casual exageration and cringe
IgE is the bane of my existence
@@izzy_theog9658 In this case (allergies) it is IgE. There isn't an "IgN".
Just a little side note: the Memory Cell in this episode isn't a T Cell. He's a Memory B Cell. In the show, he's shown running a library filled with information about previous infections, which B Cell uses to make his antibodies.
David Guthary awww my mistake. Thanks for clarification
Dr Hope's Sick Notes yup. You probably thinking that certain military guy with a pink notebook. 😁
@@Lexiand Dendrite?
Tria Maxwell no there IS a memory T Cell appearing in the Influenza episode. He does look like the black uniform-ed military guys (like the Killer T cells does) but his hat says “MEMORY” (not the usual “KILLER”) and he brought a pink heart patterned notebook.
@@Winu-bignsmall Sorry. 3:35 AM here. Thanks for the correction. So do you go dawwwww when you see platelets?
Me: mom I don’t want to be a doctor
Also me: *watches a doctor watching a medical anime*
Same here
Interviewer: This job requires you to have a PhD in Human Microbiology.
Me: Not to worry. I've watched all episodes of Cells at Work.
Interviewer: OH S**T YOU HIRED!!!
The way I see all the destruction and mayhem seemingly being caused by the pollen is how the cells perceive the 'invasion.' In that one scene you showed, it seemed like the panicking cells knocked into the pollen, *pushing* it into the building. So it was still the cells over-reacting that caused the damage and misapplying blame.
Now I'm sure of it. "Cells at Work" is a misnomer. This show should have been called "Cells at War".
That Cells at Work Black.
oh nuu theres a hemmoraghic shock at episode 12 (sorry if i spelled anything wrong)
When war occurs everyday it just becomes another task of work
when it comes to the immune system it really is a professionnal army, so they are "just doing their job" like any day.
@@joshgellis9463 wait wat
This is so much better than other non-content based reaction videos. Love the way you stop things and then use visual effects and analogies to make the learning fun. Very professional and inviting.
Also, kind of apropriate the cat muked up your cell a bit since cats can carry a lot of pollen in their fur and often cause allergies themselves.
I really like that the steroid didn't actually kill the cells, but it scared the heck out of the mast cell and B-lymphocyte which suppressed their activity. The level of detail this show works on sometimes feels like Easter eggs. Your input is a fantastic addition to this really fun bit of education (supplement?). I've suggested this show and your reaction series to my microbiology professor for his intro to microbio course.
Bursa of Fabricius is involved in B cell development in birds!
Even as a vet student, I loved the show and I thoroughly enjoy your explanations throughout the video. Looking forward to your future videos!
But srsly this dood really does magic with this :o
Like,he makes 2 of my fav things into one
ANIME AND SCIENCE!
Cheers for this guy! :D
I cannot believe how fast I clicked on this video when it popped up ☺️☺️👍🏾
same
I can say these videos are for learning and not just an excuse to watch cute animated girls.
Likewise
I never knew how much I needed to see a Steroid Terminator until this day
"prevention is better than-" *ad plays*
soooo get adblocker basically?
The Memory cell shown here is actually a Memory B cell, it's more explicit in the manga, showing how they share an office space and work on problems together. A memory T cell shows up later on when the main Killer T cell becomes one.
PS
I love how you stop to visually explain the real science behind what is happening in the show!
Yes! And just like the hilarity of the red blood cell that's always lost, we have a memory B cell who struggles to remember 😂.
"Tea being spilled, that's a very English problem, I can relate to that."
As a American, and a citizen of Boston, Massachusetts....
[[[[[[[[[[[PATRIOTIC FREEDOM INTENSIFIES]]]]]]]]]]
Tristan Ritland xD
Don't worry, you're very free from good tea. *sips*
@@FFKonoko Don't worry, our $1, tax-free arizona tea cans are tripled in price in the UK
**chugs**
Even if it were a third of the price it probably wouldn't sell. We chose India over the US to keep for a reason
*is drinking chi tea out of an eagle mug at this exact second.*
Can't wait until you get to the Cancer episode, it's an emotional one.
Hint hint*
Richie 64 more like *Spoiler Spoilers
Cancer might be my favorite character in the whole show/manga, besides our main white blood cell himself. ...Which sounds really weird out of context lol
True 😭
kaneki ken :(, he didn't want to become a ghoul, just like cancer sama
As an Engineering student, this is so awesome
Kirby Salonga Try to create Steroid Robot! XD
One doesn't need to be an engineering student to be amazed by this.
*At Doctors meeting:*
Doctor: Why're you late?
Doctor: I was watching anime.
My teacher asked me why is my Biology so good
I answered:"ANIME"
And then everybody clapped
YAS
-What's your name?
-Doctor.
-Doctor who?
-Doctor Hope.
Doctor? Who's a Doctor? (DW - S1E1 1963 - An Unearthly Child)
Oh you're using your make-up name.
"Every story benefits from having a Terminator with a mini-gun."
Words to write by.
I'm really enjoying this ongoing reaction series. Definitely keep it up. "Steroid Terminator" may be my new favorite phrase.
Side-note: The "Helper T Commander" cell is unexpectedly attractive.
in later episodes you'll watch more about him and his story
... He is... So is the White cell....
We have reached a point in humanity where we find body cells attractive (I know they're kind of represented like people but still), I-
@@SeraphinaAizen1 NK Cell if gorgeous
@@SeraphinaAizen1 Just do it!
Feel the warmth and shield that he provides for you.
Mama macrophage is goat
I'm sorry. I just lost my shit when he was like "I'll find once I EAT IT!" 😆😆😆😂😂😂
Really enjoying your review on the series! A nice refresher for immunology - this coming from a biomed student :)
I find it a nice little detail that the gun the B Cell is holding is the same shape as an antibody (a Y shape). Neato!
So cool! Totally missed that. Nice one
And the ad on the video: Mucinex. Perfect.
Yet another really enjoyable video; thanks Dr. Hope!
A wild Cells at Work! review appeared! 😮 I actually wondered what happened, not seeing ANY Sicknotes video for the past 3 weeks. Last time I saw something Cells at Work! related was in an Instagram snippet in the 86th Floor Cosplay where a certain doctor is wearing a cartoonish cosplay of a bacteria. 😂 Nice to see you still continuing the series...#6 is an episode with chock full of information to discuss too.
P.S. Cells at Work! will air a winter special around December 26 and I think it may be aired on Crunchyroll, so if you can make a review close to that time, it would be great, seeing it would just be fresh.
7:47 cat owners can relate
My cat leaves muddy pawprints because she hops in the bathtub and laps puddles from the most recent shower. -_- I don't understand her. She has two water bowls and they're both clean.
The fact that a doctor calls this good prep for med school is amazing
6:33 what.. what are you talking about? Is this not what’s really happening in my body?
They are literally snot rockets
@Gilbert Ber2 Careful on what you say there. The FBI might bust your door.
@Noblesse Obligee um that platelet is likely only a few days old, so yea it is definitely underage (they only live 8-9 days).
@@crulius.pontanian no bro. you're forgetting to scale their age maturity according to their max life expectancy. young adults sounds about right
@Noblesse Obligee I think you just described the premise for some doujinshi that may be already released in some corner of the last comiket. LOL
Oh my god I love your reacts. I swear you make watching this show better and better. I'm glad to be learning from you. THANKS!
I wish there was more medical related anime, just so I can watch Dr. Hope review them!
Ikrrr, there’s Dr.Stone manga but it’s more scientific than medical but it’s still great nonetheless ^^;;(it’s getting an anime next year tho yaaayyy)
Try "Black Jack".
Super Doctor K (manga) and Kusuriya no Hitorigoto (light novel and manga, it has more about old herbal medicine), and then pharmacy of another world (light novel and manga most of the time diagnosis and medicine creation and also the running of pharmaceutical industry)
Like Black Jack
Look at the way that you designed the antigens. It has the same design as the gun that the B cell has. 😂
I'm so sad, he switched his electric guitar for an acoustic. I was so used to the electric guitar.
20 minute vid?! What a special day for me.
never clicked a video so dam fast, I might have caused some of my red blood cells on my index finger to wonder what the hell was the "earthquake" about.
As long as you didn't get an "abrasion" from that stray piece of paper while you did it.
his voice is so friendly and sincere
Now I understand what antihistamines really are and do
That's esteroids: different from antihistamines 😊
I remember when I saw the episode I was so confused but then I realized what the steroid was doing wasn't killing tissue which is what the buildings are but it was leveling the town. Earlier in the episode, in a very brief moment, the cells were screaming that the town was rising and getting pushed up because it was swelling.
(Anime Release! Phoenix Wrightu no Jutsu!)
*Slams Desk*
What if the reason there were paw prints found on the picture which were confirmed to be of the defendant's cat was because it was the cat's picture all along, and his paw prints were his signature of the painting!
...GUILTY!
Love the show, and love your explanations. While the show does a fantastic job, it’s great to actually discuss how it relates to real life. Please continue to review the show Doctor!
Apart from the amazing content and beautiful graphics of the anime, can we take a moment to appreciate those who create the subtitles~ the anime is so medical info-packed and as a translator/interpreter, medicine is such an intimidating field that I tend to stay away from 😂😂😂😂😂😂 the translator(s) of this anime really did a great job~
I find it more enjoyable to watch doctors reacting to Cells at work rather than just me watching the anime and then having to google from time to time 😅😅😅
“He’s just a lost male sex cell in a protective layer trying to find a female flower to germinate.”
That’s deep
The allergy episode was one of my favorite from this show. I suffer from seasonal allergy so I can relate to it. I must say though, Im currently taking an Anthropology class on Human Variation and we are discussing the Immune System and Cells at Work has helped me out so much because thanks to it I feel more prepared on this subject. Then with Dr. Hope's input it helps ingrain the info better. I really like the small drawing/cut-outs of the cells Dr. Hope uses to explain as it makes it easy to digest the info. Im a very visual learner so you have no idea Dr. Hope how helpful these videos are for me 😁👍🏻
I like this 20min format
I don't think Memory Cell is part of the T group. Kinda more like he's part of the B group. In the opening theme of the show, we see Memory Cell and B cell are together (go away, fujoshis. this for the sake of human anatomy I'm talking here) Which means, he's a Memory B Cell, but not a Memory T Cell
You are right! A few people pointing this out. Thanks for clarifying
You are right, later they will show us the Memory T Cell
You say that like it matters to the fujoshi... It doesn't, they are hard at work with their doujinshis right about now.
@@LuizAlexPhoenix Which kind of doujins? BL? That's the kind I despise them. Their BL doujin agenda
@@redacted8983 yep, there are only 2 t cell, cd4 t cell/ t killer and cd8 t cell / t helper.
Give us more Cells at work, please... it's great to hear you talk about it.
I am a medical laboratory science student and watching "cells at work"+you(doctor) expanding the topic, helps me prepare for my upcoming exam in immunology & serology. Haha thank you Dr!
I love the fact that you seem a little more excited with each one of these videos. Keep up the good work. Explainations and predictions are on point 😀
The king of youtube is back
Yuri Yuki THAT’S RIGHT! Let the feast of learning commence!
I had a hive (urticaria) breakout one time and the way the episode demonstrates medication use for mild to severe allergies (such as hydrocortisone or a higher potency such as methylprednisolone) makes me feel a bit bad for my own cells in my body. Really important to stay hydrated and relaxed too. ;)
To be fair the representation of a steroid like hydrocortisone was a bit exaggerated in this episode, as well. But it fit a theme of over-exaggeration being the problem. A cool thing with the show, though, is you never hear about the body but if they're getting steroids for a standard pollen reaction, they must have had a very severe reaction and possibly even ended up in the hospital. Otherwise much less potent medicine would have been fine.
Dr.Hope explains a steroid better than I could, but they don't cause as much collateral damage as represented in the anime.
I need more memory cells in my brain...
Now what was I talking about...?
I started watching Cells at Work with my daughter, and after we watch every episode, I come to your channel to get some extra depth explained about what's happening. I really enjoy your content, and after we finish Cells at Work, I'm gonna stay subscribed and check out your other work. Good stuff!
Is it 12:30am where I live? yes. Do I plan to watch all 20 minutes of Dr. Hope geeking out and teaching me more about anatomy and physiology than I ever planned on learning? Also yes.
P.S Was totally worth it, but now I really need to get to bed lol. Darn you Dr. Hope for your amusing and informative content! -shakes fist-
Yesss, can't wait for the cancer episode!!! This was amazinggg!!!
*person watches cells at work* barely any views
*an non anime watcher and doc watches cells* 1462694379937732 views.
17:13 I was immediately reminded of Drix from Osmosis Jones. I love this.
The fact that he's just smiling everytime😂😍 Our doctor is really enjoying it hahahahah
I can't even finish the anime until he makes a video about the episode so that I fully understand what happened, lol. Well worth the wait though and about the only time I'm like BUT EDUCATION I need to know!
Same situation here.
oh my god, he has a cat.
This is the culprit:
instagram.com/p/Bq1uwGsBz1Z/
@@DrHopeSickNotes Ahww, she's so beautiful! I guess she just wanted to learn about antigens too :)
Ovaries explode.
I feel like I’ve been waiting for this episode forever!
(I sneezed due to allergies three times while writing this 😂)
I am anaphylactic to peanuts and mildly allergic to a long list of things, so getting this explanation is extremely helpful. Thank you!
Thanks for reviewing this episode! As a sufferer of allergic rhinitis for more than a decade, it really made me feel better. Antihistamines are my saviors but yknow, they make me sleepy.
It sucks having allergic rhinitis bec it's difficult to do things such as touching dusty things, hugging teddy bears, too much face powder, perfumes, and other things. I love how this episode covers the whole process for the non-medical people to learn. Very educational!
Yay! New episode. Thank you for these! I'm currently in Alaska still recovering from the recent earthquake, and this is really helping my morale stay up. Perfect timing
Every time a practicing doctor looks up medical information on Wikipedia, an angel gets its wings.
Any time a person practicing in a field looks up information about that same field on Wikipedia, an angel gets its wings.
Yay! I always love Cells at work reviews by you! Excited when they come out
"Every story benefits from a terminator with a minigun."
Best medical advise I've heard all day! 👍
clericneokun 'advise' is used in caution: such as: "advise me, sir." 'advice' is the correct word you're trying to spell: "what's your advice?" referring to giving beforehand information.
it may not seem to have a difference, but there IS. *_LOL_*
*_Future Teachers At Work_*
6:25 - the pollen does not cause damage, but maybe some cell saw it and did a damage report just in case ("well, it has not damaged anything yet, but I'm sure it will, better call the police/immune cells anyway", "HELP, the pollen is killing everything its path!") and then the immune cells overreact causing the allergic reaction.