Thank you guys so much for watching! Please leave us a like if you enjoyed the video. We truly do appreciate it! Also we love hearing your comments so feel free to tell us what you think of the video. We hope that after this lesson, you will have a good understanding of the differences between DI and SIADH and what they share in common. You should be able to better identify each of these, what you would expect to see in your patients, as well as how we diagnose and treat each of them. Don't forget to check out these other great lessons that we have available! Hemodynamics: ua-cam.com/play/PL2oVjKTYocdMBZlcIcWlESbOFFaGugQS2.html Shock: ua-cam.com/play/PL2oVjKTYocdPP0K8Fi49GfUgprICS-xMf.html Blood Tubes - Order of Draw: ua-cam.com/video/mAmwdDdbkUI/v-deo.html Arterial Blood Gases: ua-cam.com/play/PL2oVjKTYocdMz1qF-3iS6iUZ-R_fKbeJw.html ECG/EKG Interpretation: ua-cam.com/play/PL2oVjKTYocdPMaNwn4xbg6xAIaAnyraMj.html Glasgow Coma Scale: ua-cam.com/video/zYwJVPIjW6I/v-deo.html Heart Failure: ua-cam.com/play/PL2oVjKTYocdNdFoS31yGhylKwib9lRf73.html Don't forget to check us out and give us a like on Facebook as well! facebook.com/ICUAdvantage
Eddie!!! Thank you SO much! You have a natural talent for teaching! Thank you, thank you, thank you. This video helps make it stick!!! You’re videos have been so helpful to refer back to. Totally loving them ❤️
You said that DI causes you to be unable to dilute the urine. Do you mean unable to concentrate the urine? Since that's what ADH does. Love the videos though!
@5:45 Hi Eddie, shouldn't insufficient ADH or insensitivity to ADH lead to inability to concentrate the urine rather than diluting the urine? and ultimately a volume loss?
Just now seeing this comment. YES! I completely butchered that part. Not having the effect of ADH means we will not concentrate leading to dilute urine and thus the volume loss. Good catch.
Why is it that it’s called diabetes insipidus when it has nothing to do with diabetes or even the pancreas for that matter I’ve always wondered that. Really makes no sense.
My nursing textbook says that is called Diabetes because the signs are similar to DM. I agree that it does not make sense and that this disease is due for a rebranding.
Because it presents as similar symptoms (polyuria, polydipsia). It seems in the past doctors would taste the urine to differenciate between diabetes mellitus (sweet in latin) and insipidus (tasteless in latin). In the former, sugar in the urine pulls water in, and in the later, the absence of or insensibility to vasopressin prevents water resorption
Hi Eddie can you tell me what you think this is pointing to? Below low reference limit Serum urea level 1.8 mmol/L [2.8 - 8.1] Below low reference limit Serum sodium level 133 mmol/L [136.0 - 145.0] At the low end GFR calculated abbreviated MDRD > 60 mL/min [60.0 - 90.0] At the low end Serum total protein level 66 g/L [66.0 - 87.0] Urine: trace haemolysed blood Urine protein test = trace
This is Claude's response "Based on the information provided, it appears you're referring to a set of laboratory test results, specifically blood and urine tests. Let me break down what these results might be indicating: -Low serum urea (1.8 mmol/L): This is below the reference range (2.8 - 8.1 mmol/L). Low urea can sometimes indicate liver problems, malnutrition, or overhydration. -Low serum sodium (133 mmol/L): This is slightly below the reference range (136.0 - 145.0 mmol/L), indicating mild hyponatremia. This could be due to various factors such as certain medications, hormonal issues, or excessive fluid intake. -GFR (Glomerular Filtration Rate) at the low end of normal: This suggests kidney function is at the lower end of the normal range, which may warrant monitoring. -Serum total protein at the low end of normal: This could potentially indicate issues with nutrition, liver function, or protein loss. -Trace hemolyzed blood in urine: This suggests the presence of red blood cells in the urine, which could be due to various causes ranging from vigorous exercise to kidney or bladder issues. -Trace protein in urine: This small amount of protein in the urine could be normal or might indicate early stages of kidney issues if persistent. Taken together, these results might point to: -Possible mild kidney function issues -Potential electrolyte imbalance -Possible nutritional concerns"
Sorry I totally missed this comment. I actually wasn't aware of this but did some digging. Looks like its specifically for nephrogenic DI and prevents polyuria and increases urine osmolality. Seems counterintuitive to give a diuretic, but it sounds like the use of Thiazide causes Na and Cl levels to rise in the distal convoluted tubules, leading to adenosine to be released, causing vasoconstriction of afferent arterioles and thus a reduction in GFR. Pretty interesting!
They both are hypotonic. D5W, the dextrose is metabolized leaving us pure water, making it hypo, and then yeah 1/2 NS is 0.45% NS, so hypotonic as well. 😊
Thank you for finding time to respond to each and every questions from the confused 😁😁😁 I am okay with OPERATING ROOM, though. ICU will give me heart attack 😁😁😁
Haha, its defiantly a high stress environment thats for sure! :) I'm sure OR can be stressful too when it doesn't go well. And I certainly try my best, but its getting harder and harder as the channel grows. I certainly am falling behind and probably soon won't be able to keep up with everyone :(
So sad I only found you today. But, I am glad I found this page today and get so much clarifications on Endocrine problems.
Thank you guys so much for watching! Please leave us a like if you enjoyed the video. We truly do appreciate it! Also we love hearing your comments so feel free to tell us what you think of the video. We hope that after this lesson, you will have a good understanding of the differences between DI and SIADH and what they share in common. You should be able to better identify each of these, what you would expect to see in your patients, as well as how we diagnose and treat each of them.
Don't forget to check out these other great lessons that we have available!
Hemodynamics: ua-cam.com/play/PL2oVjKTYocdMBZlcIcWlESbOFFaGugQS2.html
Shock: ua-cam.com/play/PL2oVjKTYocdPP0K8Fi49GfUgprICS-xMf.html
Blood Tubes - Order of Draw: ua-cam.com/video/mAmwdDdbkUI/v-deo.html
Arterial Blood Gases: ua-cam.com/play/PL2oVjKTYocdMz1qF-3iS6iUZ-R_fKbeJw.html
ECG/EKG Interpretation: ua-cam.com/play/PL2oVjKTYocdPMaNwn4xbg6xAIaAnyraMj.html
Glasgow Coma Scale: ua-cam.com/video/zYwJVPIjW6I/v-deo.html
Heart Failure: ua-cam.com/play/PL2oVjKTYocdNdFoS31yGhylKwib9lRf73.html
Don't forget to check us out and give us a like on Facebook as well! facebook.com/ICUAdvantage
Eddie!!! Thank you SO much! You have a natural talent for teaching! Thank you, thank you, thank you. This video helps make it stick!!! You’re videos have been so helpful to refer back to. Totally loving them ❤️
Woohoo!! You are so very welcome Adelaide! I really appreciate the kind words and it makes me happy to know others find these videos helpful.
You said that DI causes you to be unable to dilute the urine. Do you mean unable to concentrate the urine? Since that's what ADH does. Love the videos though!
Yup! Definately a flip of words there! DI = extremely dilute urine.
Love your videos!!!! The best for nursing school!!
Thank you so much Alyssa! 😊 Glad they have been helpful for you.
Thank you for clarifying the difference between these! This is a well detailed and understandable explanation!:)
So glad to hear this and happy to hear it was helpful
I agree
I have diabetes insipidus. I was diagnosed when I was 6. I was happy to see you teach about it. Keep up the good work.
Excelent work! Thank you for making this easier to understand.
Thank you so much Jose! Really appreciate the comment and glad it was helpful for you.
GOOD JOB EDDIE!
ADH secreted by posterior pituitary gland
@5:45 Hi Eddie, shouldn't insufficient ADH or insensitivity to ADH lead to inability to concentrate the urine rather than diluting the urine? and ultimately a volume loss?
Just now seeing this comment. YES! I completely butchered that part. Not having the effect of ADH means we will not concentrate leading to dilute urine and thus the volume loss. Good catch.
That is what
I thought also. Ty for bringing this up😁
Why is it that it’s called diabetes insipidus when it has nothing to do with diabetes or even the pancreas for that matter I’ve always wondered that. Really makes no sense.
My nursing textbook says that is called Diabetes because the signs are similar to DM. I agree that it does not make sense and that this disease is due for a rebranding.
Because it presents as similar symptoms (polyuria, polydipsia). It seems in the past doctors would taste the urine to differenciate between diabetes mellitus (sweet in latin) and insipidus (tasteless in latin). In the former, sugar in the urine pulls water in, and in the later, the absence of or insensibility to vasopressin prevents water resorption
@@simonparadis4159 thank you 😊
Hi Eddie can you tell me what you think this is pointing to?
Below low reference limit
Serum urea level 1.8 mmol/L [2.8 - 8.1]
Below low reference limit
Serum sodium level 133 mmol/L [136.0 - 145.0]
At the low end
GFR calculated abbreviated MDRD > 60 mL/min [60.0 - 90.0]
At the low end
Serum total protein level 66 g/L [66.0 - 87.0]
Urine: trace haemolysed blood
Urine protein test = trace
This is Claude's response "Based on the information provided, it appears you're referring to a set of laboratory test results, specifically blood and urine tests. Let me break down what these results might be indicating:
-Low serum urea (1.8 mmol/L): This is below the reference range (2.8 - 8.1 mmol/L). Low urea can sometimes indicate liver problems, malnutrition, or overhydration.
-Low serum sodium (133 mmol/L): This is slightly below the reference range (136.0 - 145.0 mmol/L), indicating mild hyponatremia. This could be due to various factors such as certain medications, hormonal issues, or excessive fluid intake.
-GFR (Glomerular Filtration Rate) at the low end of normal: This suggests kidney function is at the lower end of the normal range, which may warrant monitoring.
-Serum total protein at the low end of normal: This could potentially indicate issues with nutrition, liver function, or protein loss.
-Trace hemolyzed blood in urine: This suggests the presence of red blood cells in the urine, which could be due to various causes ranging from vigorous exercise to kidney or bladder issues.
-Trace protein in urine: This small amount of protein in the urine could be normal or might indicate early stages of kidney issues if persistent.
Taken together, these results might point to:
-Possible mild kidney function issues
-Potential electrolyte imbalance
-Possible nutritional concerns"
Thanks a lot!
Did you know that thiazides are used to treat DI but can cause SIADH?! Can you explain?
Sorry I totally missed this comment. I actually wasn't aware of this but did some digging. Looks like its specifically for nephrogenic DI and prevents polyuria and increases urine osmolality. Seems counterintuitive to give a diuretic, but it sounds like the use of Thiazide causes Na and Cl levels to rise in the distal convoluted tubules, leading to adenosine to be released, causing vasoconstriction of afferent arterioles and thus a reduction in GFR. Pretty interesting!
Hi Eddie. May I clarify the treatment to DI as far as fluid replacement? D5is isotonic and 1/2 NS is aka 0.45% saline is hypotonic right?
They both are hypotonic. D5W, the dextrose is metabolized leaving us pure water, making it hypo, and then yeah 1/2 NS is 0.45% NS, so hypotonic as well. 😊
Thank you for finding time to respond to each and every questions from the confused 😁😁😁 I am okay with OPERATING ROOM, though. ICU will give me heart attack 😁😁😁
Haha, its defiantly a high stress environment thats for sure! :) I'm sure OR can be stressful too when it doesn't go well.
And I certainly try my best, but its getting harder and harder as the channel grows. I certainly am falling behind and probably soon won't be able to keep up with everyone :(
Great cover 👍👍👍👍👍
Thank you!
Can you do cancer
Thanks for the suggestion!
Posterior pg
Yup! 😊