Pain Killers in Pets: all you need to know about anti-inflammatories
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- Опубліковано 3 чер 2024
- Pain killers in pets are crucial in many conditions to help them remain comfortable. In this video I run through all you need to know about the most common ant-inflammatories in dogs and cats.
Find out how they work, what side effects they might cause and why as well as what we can do to keep them a safe as possible and reduce their side effects.
The most common pain killers in pets, both dogs and cats, are the non-steroidal antiinflammatory drugs, also known as the non-steroidals or NSAIDs.
They are used as pain killers, to reduce inflammation and swelling and also to reduce a high temperature. While there are many different options for pain killers in dogs and cats, none of the others them have all of these effects.
The most common uses of non-steroidals in dogs and cats are the management of chronic pain conditions such as arthritis as well as for pain relief following injury or surgery. These drugs also have some anti-cancer effects, an area of their use where research is ongoing and recommendations changing.
There are many different drugs within the non-steroidal anti-inflammatory class including carprofen, meloxicam, firoxocib and mavacoxib to name but a few. These are then sold under many trade names including Rimadyl, Metacam, Previcox and Trocoxil.
Non-steroidal anti-inflammatories work by stopping the enzymes from working that make pro-inflammatory chemical know as prostaglandins. These prostaglandins cause swelling, an increase in temperature as well as amplifying the pain signal sent to the brain by the local nerves. The enzymes that are blocked are known as the COX enzymes, specifically COX 1 and COX 2. COX 1 is actually responsible for the function of normal, healthy body processes. These include maintaining the intestinal lining and ensuring adequate blood flow to the kidneys.
COX 2 however is the enzyme that goes into action whenever damage takes place and results in the production of these inflammatory prostaglandins resulting in pain and inflammation.
We want our drugs to block COX 2 and not COX 1. Most readily accessible human NSAIDs do not do this in dogs and cats and as a result side effects are really common when given to our pets.
Our pet specific anti-inflammatories however are considered COX 2 preferential or COX 1 sparing
the most common side effect is mild gastrointestinal upset resulting in diarrhea and vomiting as well as lethargy and inappetence. This appears to happen in 2-9% of patients, with reports varying slightly. If treatment is continued despite vomiting or diarrhea being present then there is the risk of intestinal ulceration developing which may progress to full perforation.
Other side effects do happen although are considered rare. Dogs are more prone to liver damage which occurs in around 1-in-2000 patients and is generally reversible so long as it is detected early and the damage is not too severe.
Cats on the other hand are more prone to kidney damage. While this can happen following a single injection, kidney damage is very rare when our NSAIDs are used appropriately.
Any patient being given these drugs should be monitored at home for side-effects and if there are any concerns then they should be stopped and you vet consulted. As well as looking out for these symptoms it is advisable for any dog or cat taking these pain killers to have blood and urine testing carried out on a regular basis.
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is metacam safe for cats: • Is Metacam Safe for Ca...
treatment of arthritis: • Treatment of Arthritis...
home management of arthritis: • Holistic Arthritis Man...
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Thanks for this info!
bless your soul 😇
What’re your thoughts about Carprofen for a dog who hurt himself like pulled a muscle or something?
When ever someone tells you you need a pharmaceutical for inflammation, how do they know you have inflammation without a SED Rate test? Always ask for the tests to show the alleged inflammation. It could be radiating nerve pain or other pain that don't respond to these NSAIDS.
How have pain killers helped your pets quality of life? I'd love to know!
Sign up to my FREE arthritis mini-course to help your pet live a pain-free life : bit.ly/arthritis-course
My dog has been taken off long term steroids he has since been really suffering from arthritis the steroids were masking it. I’m hoping that when the steroids are out of his system nsai will work.
I have a senior cat who is 15 years old and after blood work they said he has very good blood results for his age. Due to hip pain etc arthritis they gave me a tiny little bottle of Metacam (the bottle says it is 3ml) the lid is almost bigger than the little bottle. However the confusing part is they told me to give him 5kg (I am in Canada) every 24hrs at first for 7 days then to reduce it to effective amount. My only concern is that the syringe has markings on it but no measurement. In other words it says 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 but does not say ml or anything and the syringe came with the bottle in the box, and the syringe says right on it the name Metacam 0.5ml written on one side. If the bottle has just 3ml how can I be giving him 5ml per serving for 7 days.. I am confused.. am I not supposed to use the 5 on the syringe as the 5ml prescribed dosage? I will call my vet tomorrow to find out as today is my first day using it. I can provide pictures if you want in an email as well. I just don't want to overdose him... maybe I am supposed to give 0.5 rather than 5? arrg.
The numbers on the metacam syringe relate to dose for a specific weight to the 5 would be for a 5kg cat. A 3ml bottle will only last you a week at most at that dose so you may want to ask about getting a bigger bottle if your cat does well on it (they come in 15ml and 30ml sizes too).
hope your cat is feeling more comfortable soon
ok that makes sense.. thank you.. I am not feeling as if I OD'd him .. he does seem relaxed and sleepy but cozy after an hour or so.. I am going out tonight but will be setting up a webcam on skype with auto answer so I can watch him etc. but he looks just like he is going to take a nap and seems ok.. I will for sure talk to the vet tomorrow but I feel much better knowing what those numbers mean as it matches his size.. which google says is 11lbs and that seems about right ;) Thank you.. I love your channel and just found it.. I will share it on my facebook as you are very clear, and very quick to respond wow. :) Have a great night
How about meloxicam
Meloxicam is a non-steroidal anti-inflammatory and I've discussed it specifically in my video is metacam safe for cats - ua-cam.com/video/Lb9p7iIOask/v-deo.html hope that helps
I gave my 6 yr old Old English Bulldog Hank Previcox perscribed to me by the vet after a minor cist removal. I gave him half a pill 5 hours after he came home and he went into distress 10 minutes later he was acting scared and dizzy. He collapsed and we rushed him to a emergency vet 25 minutes away (closest one) and he went into cardiac arrest in the parking lot. We ran him in and the did CPR but Previcox had killed him. He had no health issues besides allergies. I am destroyed over this but after looking into his medication I realized my people have a similar story. PREVICOX KILLED MY DOG DO RESEARCH BEFORE YOU GIVE THIS TO YOUR DOG, I WISH I HAD.
I’d go with CBD it’s better than any form of nsaids and I know this for an absolute fact as I take CBD daily and used to take several types of pain pills none worked for me and some caused severe addiction in me and I’m now in a program for methadone due to severe knee damage including arthritis in my knee too and let me tell you nsaids do not work they are a joke mostly and caused me to vomit blood and feel worse pains and I tried CBD and thc and it’s worked lol painkillers real ones are too addicting but work amazing for pain and CBD isn’t addicting and works well for pain but not 100% maybe like 50-70% but no side effects with CBD at all just drowsiness and relaxation no bad at all lol CBD is the way to go for several ailments in humans and animals so you should try it people they sell CBD at petco and it works better than what most vets with prescribe an animal lol and safe !
what about fentanyl patches
they have their place for sure but can be dangerous and have the potential for abuse so many vets are not comfortable sending patients home with them in place making them of more use short term in the hospital situation. The patches also have a really variable effect in pets as they are designed for human not dog or cat skin
Bo Fyffe that’s overkill lol fentanyl should be banned for good it’s the number one drug in history that’s killed the most people ever ! All bad that shit needs to go ... I’m an opiate addict and never been stupid enough to take fentanyl and the patches suck ass don’t absorb well in the skin and people put em in they mouth and overdose like idiots !!! I got to methadone clinic I’ve seen it all
CBD drops 👑
Can the music! Great information ruined by inappropriately cheerful canned music. Why?
Haven’t added music for 2 years now
@@OurPetsHealth oh good. Such a good source of information!
War on drugs is causing inhumane pain in animals, nsaids are not enough
Cox blockers......lol!