Gabapentin - 5 things you should know (in dogs and cats)

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  • Опубліковано 22 тра 2024
  • 🐾 Are you a veterinary professional or a pet owner who wants to know more about the ins and outs of gabapentin treatment. Or perhaps you're interested in neuropathic pain management, conditions like canine Chiari malformation and syringomyelia, feline hyperaesthesia syndrome, and feline orofacial pain? This video is for you!
    🧠 Dive into the world of Gabapentin and learn how it works to alleviate pain and discomfort in dogs and cats. Discover the mechanisms behind its effectiveness in managing neuropathic pain, anxiety and related conditions.
    🐶🐱 Learn the essential tips on administering Gabapentin safely and effectively to your pets, ensuring they receive the relief they deserve. We'll cover dosage, frequency, and the importance of veterinary guidance.
    💊 Explore the metabolism and elimination of Gabapentin in a pet's body, helping you understand how long it stays in their system and when to adjust doses.
    🚫 We'll also discuss potential adverse effects to be aware of, ensuring the well-being of your beloved companions while using Gabapentin.
    🔒 Finally, don't forget that Gabapentin is a controlled drug, and it's crucial to understand the legal and ethical aspects of its use.
    Join us in this informative video and become a Gabapentin expert for your pets' health and comfort. Whether you're a veterinary professional or a concerned pet owner, this knowledge can make a significant difference in your pet's life. Subscribe and hit the notification bell to stay updated on more informative content! 🐕🐈👩‍⚕️👨‍⚕️ #GabapentinForPets PregabalinForPets #NeuropathicPainManagement #PetHealth #NeuropathicPain #Pregabalin #Gabapentin #syringomyelia # Chiari #feline_hyperaesthesia_syndrome #hyperethesia #hyperaesthesia #PetPainManagement #CatsAndDogs #VeterinaryMedicine #AnimalHealth #PetCare #ChronicPain #PainRelief #FelineHealth #CanineHealth #AnimalWellness #Neuropathy #VeterinaryTreatment #PetMedication #AnimalPainManagement #CatHealth #DogHealth #VetAdvice #PetLovers
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КОМЕНТАРІ • 33

  • @heatherjaggers5884
    @heatherjaggers5884 5 місяців тому +1

    I didn’t know we should start low on the dose and it makes sense because of the range. (I’m a vet nurse.) This video is loaded with helpful information-thank you!

    • @clare-neurovet
      @clare-neurovet  5 місяців тому

      thank you - glad you found it interesting

  • @tistelblomma
    @tistelblomma 8 місяців тому +1

    Interesting! You explain everything so well.
    I have been on gabapentin myself for 2 years due to a necktrauma so I found this really informative both as a vet and as a patient myself.

    • @clare-neurovet
      @clare-neurovet  8 місяців тому +1

      so glad that it was useful ! Hope that your pain is controlled

    • @kathycrawford4652
      @kathycrawford4652 12 днів тому

      this is so informative. they want my cat on this because she's declawed and has wind up and flicks her front paws and chews on them. is this something it should be used for. if not, what else will help?

  • @troismals
    @troismals 6 місяців тому +2

    Many have reported it caused extreme weakness in their dogs’ hind legs to the degree they could not stand. The dogs reportedly were dragging their hind quarters. Some reported stopping the drug and seeing an improvement. Alarming.

    • @clare-neurovet
      @clare-neurovet  5 місяців тому

      thanks for mentioning this. In my experience, this is not an issue if the drug is dosed appropriately and for a dog / cat that is suffering with neuropathic pain. However I have seen it as an issue when given high doses and when the dog/cat did not have pain and / or had another issue such as weakness from polyneuropathy.

    • @troismals
      @troismals 5 місяців тому +1

      I experienced it with my dog. Can you comment on how to reverse those effects? It has been very alarming. I appreciate it.

    • @clare-neurovet
      @clare-neurovet  5 місяців тому +1

      I would check 1) is the dog in pain or is there some other issue which is being misinterpreted for example weakness making it difficult to rise which is misinterpreted as pain or superimposed on pain. The classic and common would be a older dog with osteoarthritis and some lower back discomfort BUT also has a polyneuropathy making them weak 2) is there another drug that would work better and not cause sedation eg NSAID or Librella. Adding this might allow a dose reduction and the two would work together 3) have you been started at a low dose 10mg/kg every 12 hours and titrated up to the therapeutic dose 4) is there are reason why this dog might be very sensitive eg kidney disease or - in my experience - a sight hound. I would go back to your vet and discuss your concerns @@troismals

  • @obi-van111
    @obi-van111 8 місяців тому +1

    teleion!!!!

  • @anjonsarker2374
    @anjonsarker2374 8 місяців тому +1

    Superb

  • @CikisHelyzet
    @CikisHelyzet 2 місяці тому +2

    Amazing content. Thank you so much.

  • @hannithang
    @hannithang 4 місяці тому

    Thank you for sharing your wealth of knowledge. My dog is on a Gabapentin trial on a high suspicion of CM/SM prescribed for 2 weeks before we determine to proceed to MRI. He’s prescribed 100mg, twice a day (every 12 hours). I like your three times a day logic, so would you advise if giving CBD oil in the late evening before bed would give my dog the extra coverage so he doesn’t dip into the pain zone. To clarify, the plan would be Gabapentin every 8 hours for two times a day, followed by CBD oil at the 24th hour. Yay or Nay?

    • @clare-neurovet
      @clare-neurovet  4 місяці тому

      Sorry ethical guidelines mean that I cannot advise on animals that are not under my care. So I would discuss this with your veterinary surgeon. Hope that things work out!

  • @simplycatsvets
    @simplycatsvets 7 місяців тому

    Excellent video, we have been using 30mg /kg on some highly stressed cats with good results as recommended by a veterinary anaesthetist.

    • @clare-neurovet
      @clare-neurovet  7 місяців тому

      that is good to know - I guess that you titrated up to that dose based on (previous inadequate) effect.

  • @user-tg7wt5is5d
    @user-tg7wt5is5d 4 місяці тому +1

    Hi Claire, what are your thoughts on Gabapentin for inflammatory pain (as in surgical pain) in cats , I see there is one study from 2018 where gaba was added into the regime prior to OVH and those cats required less rescue analgesia, is this likely from the effects on the desending pathway as you suggested? I feel we may overuse it for acute pain , but often we have less options for oral analgesia in cats aside from nsaids

    • @clare-neurovet
      @clare-neurovet  4 місяці тому +1

      For cats preoperative gabapentin has the advantage that it reduces anxiety and so for a routine procedure like a spay in a healthy cat it could help reduce anxiety in the hospital and reduce pain. It is definite advantage in a fearful animal. Pre-operatively this would mean having to tablet a cat without the aid of a food treat. Worth checking out the ISFM guidelines for cats journals.sagepub.com/doi/full/10.1177/1098612X18781391
      Postoperatively it is useful as a oral analgesic agent anecdotally.
      there is also evidence useful perioperatively in other non neurological procedures in dogs eg mastectomy (dogs) www.ncbi.nlm.nih.gov/pmc/articles/PMC4565804/
      Orthopaedic surgery (dogs)
      chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/wsava.org/wp-content/uploads/2020/01/Orthopedic-surgery.pdf
      hope this helps !
      Clare

  • @gigglingchicken8444
    @gigglingchicken8444 23 дні тому

    My dog was just prescribed pregablin for seizures or possible dyskinesia. He was on generic keppra, but his anxiety has greatly increased since he started that drug. Do you think I should be concerned in using pregablin as an alternative treatment for his seizures?

    • @clare-neurovet
      @clare-neurovet  22 дні тому

      Really a conversation to be had with your vet - I am afraid that I cannot comment on the management of individual animals although I am always happy to contact me via usual channels to ask advice on challenging cases.

  • @namelessghoul20
    @namelessghoul20 5 місяців тому

    can the 100mg capsules be split into half to use twice to get two 50mg uses?

    • @clare-neurovet
      @clare-neurovet  5 місяців тому

      fiddly and time-consuming to put the powder back into empty capsules and you will lose some but yes it can be done.

  • @deborahd.7281
    @deborahd.7281 7 місяців тому +1

    I've read that transdermal gabapentin is not well absorbed., does it depend on the specific preparation method?

    • @clare-neurovet
      @clare-neurovet  7 місяців тому

      Absorption trans-dermally will depend on the compound and the blood supply to the region and whether the solution stays on the site. There is an article here www.ncbi.nlm.nih.gov/pmc/articles/PMC8295683/ suggesting some success. In general transdermal is regarded as a less reliable method of drug administration but then some people have a daily battle with medication so one might argue worth a try in those situations.

    • @deborahd.7281
      @deborahd.7281 6 місяців тому

      @@clare-neurovet Yes, thank you for replying. I try liquid and or transdermal medications if possible.

    • @CikisHelyzet
      @CikisHelyzet 2 місяці тому +1

      @@clare-neurovetThank you for the reference material! ❤ Animals with severe oral or dental disease may need another delivery method. This is very helpful.

    • @clare-neurovet
      @clare-neurovet  Місяць тому

      @@CikisHelyzet thank you !

  • @deborahd.7281
    @deborahd.7281 7 місяців тому

    Does gabapentin interact with CBD oil?

    • @clare-neurovet
      @clare-neurovet  7 місяців тому

      Both can cause sedation which will have an additive effect. In cats in particular CBD oil results in increased liver enzyme activity and you need to monitor the ALT (whether or not giving gabapentin) and reduce the dose if hepatic impairment (whether or not giving gabapentin). That is assuming giving CBD oil at a dose that is effective for pain relief which is 0.25 -3mg/kg every 12 hours. Adverse effects are seen in cats at doses of CBD oil above 0.5mg/kg every 12 hours and the effectiveness of CBD oil for pain at doses below 0.5mg/kg have not been established. Bottom line I cannot make a good case for giving CBD oil in cats. Of course there are always people that might say they give lower doses and all is well and prefer giving this "drug" because they think "natural" (but CBD is still a drug - with drug side effects).

    • @deborahd.7281
      @deborahd.7281 6 місяців тому +1

      @@clare-neurovet Thank you for replying, I have a cat who is being treated for squamous cell carcinoma on the nose, for various reasons we did not go the surgical route and tried Imiquimod cream for a while. I am trying CBD oil for possible ant-cancer effects and general well-being and pain relief.