Avoid THIS to avoid Heart Disease [Study 268]
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- Опубліковано 12 лип 2024
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Reference
[1] [Study 268] Cai X, Liu M, Xu X, et al. Cardiovascular effects of weight loss in old adults with overweight/obesity according to change in skeletal muscle mass. J Cachexia Sarcopenia Muscle. Published online December 18, 2023. doi:10.1002/jcsm.13409
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#heartdiseaseprevention #heartdiseaseawereness #heartdiseasetreatment
This is another piece of evidence that no matter your health, losing muscle mass is really bad for you.
Agree. Rather than obesity, the real epidemic is one of an under-muscled population.
@@user-ii7xc1ry3x is it that they lack muscle or they lack using the muscle with hard exertion periodically? I would bet there are people with similar muscle content, but very differing abilities and strength And possibly other kinds of markers that show consistent use. On that note, gonna do some pushups (such as I can do.)
Or loss of muscle is an adverse health advent marker.
Or low muscle mass is a sign of the real problem: Insufficient exercise.
@@w.harrison7277This. It was never about the muscle.. not directly. It's about using them. You'll never get old and frail if you use your body enough to keep it tough. You can watch centenarians in places riding horses and other stuff that a lot of people here half their age probably couldn't do.
“Smoking is good for you “ Dr Gundry has entered the chat
😂You made my day!😂
😂😂😂
🤣🤣
Dr Saladino has changed the chat theme to honey and fruit 🍯🍌
He only kinda said that. He's a heart surgeon. He said, nicotenic acid has some cardiovascular benefit and that there is one group of people that seemed to benefit from smoking. Which they clearly do, because they live to be old as s#*%.
@@bobbarker5884 I know, but I have seen him make that statement with the intention of creating a sound bite. I do hear the benefits of nicotine discussed with regards to a positive effect on LE so would not shock me that in the proper context that smoking tobacco may have some longevity benefit. Again, very context dependent but good luck getting a human study approved
Yeah, if you lose weight as a side effect of rampant abuse of coke and meth then you'll probably have some heart complications.
As far as I'm aware, none of the hundreds of people in the study were caught abusing coke and meth. :)
When I see the methods that people use to lose weight, it is scary.
I found out David Sinclair used Forskolin and tried it myself. To this day it's the only substance I've used that I've noticed physical results within a day. I actually have to stop taking it after a few days because I end up losing too much too quickly.
As an actuary (retired) it was well known, many years before 1980 and through the 1980s, that the lowest total mortality, over a very wide age, sex, etc. groups, was about 10% higher than the "ideal weight" per AMA, AHA, etc. As I recall, since 1980, the ideal weight number has been bumped up, plus massive increase in obesity and diabetes since 1980 will have changed the curves somewhat.
The second data point is that the relative mortality risks are asymmetrical. Say the the reported "ideal weight" was 150 lbs. Then per paragraph above, optimal weight for minimum mortality was 165 lbs., 10% higher weight. But the risk for being 9% above that, at 180 lbs, is less than the risk for 9% below, at 150 lbs. In other words, total mortality at the "ideal weight" of 150 lbs. is higher than total mortality at 180 lbs. In 1980 and earlier, some of that was due to cancer (which causes weight loss) and in particular to smoking (which causes weight loss). But after adjusting for smoking, the described relationships remain. So confounding factors can be very confounding. In the example above, if 165 lbs. gives optimal mortality factor of 1.00, 180 lbs. gave about 1.10, and 150 lbs. gave about 1.20, as underweight was close to twice as bad as overweight per pound.
Could easily be because those are that low a weight would be less muscled as well, whereas 165 is likely to be moreso, especially back then when more people got some exercise. My grandps, though, has been on around 150lb pretty much all his life at average height, but works and stays quite lean, under 15% bf for sure.
It's not the weight loss everybody seeks (really), IT'S FAT LOSS !
Why is everyone afraid of say that, including the health guru's.
So true. I had surgery last October and lost 15 lbs. It was not good. I lost a lot of muscle. Fat loss is key.
Actually, what everyone seeks is not fat loss, but rather muscle gain. Not everyone should lose fat.
@@user-ii7xc1ry3x I agree in fact, I will raise that by saying, I think people can have rather high body fat, and still be very healthy if the musculature that they have is worked hard periodically. But it’s just a guess.
It just gives me shivers when I hear a celebrities advertising how they lost weight with a commercial plan without exercise as if that’s a plus. If she keeps it off without exercising, she’s going to be in a teeny tiny minority. It’s just selling shame.
Because then you have to tell people that not only do they need to eat less and do cardio but also lift weights...
Muscle is just like physionic, it prevents bad things from happening :)
Suggest in future to not post on April 1, although I did watch and see this is not a joke.
What I wonder is HOW these individuals lost weight. Did they use a Keto diet? A Whole Foods diet? What was their cardiovascular risk prior to their weight loss? Etc.
If it was keto, that would be kind of funny.. keto people reaaaaally try to insist LDL is even GOOD for you.
@@mikafoxx2717 🙃
@@peterbland7227 Can't believe I fell for it for a little while until Mr. Gil pointed out how much of an empty fallacy it really is.
No more saturated fat for me. I value research and time proven dietary advice.
@@mikafoxx2717 No they don't. They just see that there's more to LDL than the long held guidelines indicate. Most people who eat a keto diet for weight loss see a lowered total cholesterol and LDL along with lower triglycerides and higher HDL. However, certain people who eat keto diets for performance and metabolic reasons and who are already lean will find that their LDL numbers go up considerably. But their triglycerides go down and HDL rises. Their numbers are ideal, except for that LDL. And it's not just the lipid panel than improves greatly. It's all of the other markers. Liver enzymes, glycation and inflammatory markers.
@@rmcq1999 I wonder if a low saturated fat version of keto would raise the LDL as much as typical keto which is high in saturated fat.
Maybe not too far off topic… Any insight into plaque stability before, during, and right after a rapid, high amount of weight (fat) loss?
Additionally, lots of toxins are fat-soluble (and good things, like fat-soluble vitamins). So, rapid weight loss dumps lots of fat-soluble chemicals into the blood, hitting the kidneys and liver. Plus, the cells will try to burn the fat, which is a different set of chemical reactions. Plus, the fat itself may be rancid or otherwise unhealthy. Net, other things being equal, slower weight loss is preferable.
Thank you!
That‘s really interesting since people on GLP1-Agonists not only lose weight but also muscle. It‘s known that key diabetes outcomes get better but at least this is a sign that major health are missed if people just lose weight with drugs instead of lifestyle change.
Enjoying your videos…have been weight training, zone 2 and vegan as well as focussing on enough protein and leucine. Doing all the right things and seeing results. Being female and in 60s I would like to reduce extra fat from tummy and under arms and considering Coolsculpt for help. Could you please do a video on this, if it works, independent data and would you recommend Thank you.
More people in the normal BMI live to older ages, on average, than morbidly obese people. The worse off/heavier you are when you start losing weight, the harder and more taxing it can be on your heart.
There are always different variables that can go into a result and correlation does not equal causation.
I do like your dry sense of humour 😂🤓👍🏼
I don't like his sense of humor 😊
Hopefully technology will soon allow us to accurately, easily and affordably measure body composition.
Then instead of targeting pure weight loss, we can focus on strategies to lower bodyfat, while gaining or maintaining lean body mass.
I have seen the terrible effects of sarcopenia in a late middle-aged friend. The paradox of sarcopenia is that it is often in conjunction with obesity, or overweight, so by focusing just on weight loss in these people, you can actually make them functionally worse 😮
Yes, I notices anything odd at 2:20 .... On the vertical axis there is 0.70 twice. Anyway, fantastic video and very good and valuable information!
Whoops! Good catch :)
I'd like to know how / why the wt loss or gain happened? is it the stroke +immobility with 3-5 ib/wk of wt loss? or is wt gain with early stages of HF/ liver Cirrhosis + all kinds of fluids collections all around the body?
1:38 funky y-axis labeling, but harmless
Interesting plus it makes sense.
Daily fasting between dinner and breakfast is a great plan.
Posted on April 1st
Hi. Would you tell me how to deal with water weight and water retention in the body. I can lose weight with Mcdonald 's meal without soda with is around 733 cal. but I gain some weight after after eating a meal with rice which is lower than 700 cal. I think that it must be something to do with the white rice and water weight. Whenever I gain some weight, I need to eat Mcdonald, then the weight will go very soon.
Great video.
What about video regarding thiamine/b1 ?
What about it?
If I create a video called 'Thiamine/B1" without a goal, the video will tank to the bottom of the deepest oceans - it has to have an outcome, a purpose, just like anything in health. So, is there an outcome you're interested in relation to thiamine?
@@Physionic you're right
I think Ray Peats propagated substances and his approach has zero voice from the contra side of more rationalistic mediums and science based side which are not bro science (like your channel)
The topic of thiamine, supplementation of T3 and crazy substances like pregnenolone and much more of harmful things he claims under his approach about "metabolism and thyroid boosting diets " narrative would have great amount of views and probably some hate from the sect of Ray Peat and make a great video
I wish there was enough research for a leucine episode!!
I am slowly losing weight and adding muscle, increasing lift amounts
i think the ones that lost weight, needed to lose weight and hence their risk was always elevated.
Someone who does not lose weight as they are of healthy weight have less such events due to past health being better
Captain Obvious told me that people who lose weight, need to lose weight and are probably are not as healthy a cohort as those who don’t need to lose weight.
Very interesting. At my behest my partner and I are tackling our insulin resistance before we get past the tipping point for disease. We have been intermittent fasting for 6 months and 3 months carnivore. Love the diet. Love the body recomposition. Love the weight loss. We both had major osteo arthritis and pain from inflammation.
I was explaining what you explained in the video but it occurred to me that we have very different situations. He is 54 6'7" 270lbs with artery blockage, DVT and takes blood thinners. Because of this he has some COPD from lung scarring from PE's before he got diagnosed.
I am 61 5'6" 150lbs with no coronary disease. I have no barrier to exercise. I was never an athlete but did do stuff like yoga and pilates and cardio all through my youth up to age 45. He was an Olympic athlete and skier up to age 35 and still looks fairly muscular and just moves a lot of heavy things around very slowly.
I'm still a little confused as to the risk for either or both of us. I've told him that now that we have lost a little weight and our joint pain is reduced that we have to start working out a few days a week. I feel though that for him he can just use his huge body weight to build muscle plus he's a man so he still has the testosterone to help him. I got weak over the pandemic due to deconditioning and sitting around too much. As you pointed out all of the people in the study were some form of obese. Because of that significant factor it is hard to know how much risk we face compared as people who not obese but overweight. The video posed more questions for us than answers. I will look forward to seeing the whole video and more from you regard these nuanced health studies.
It seems you are on the right track, I was diagnosed with copd, ILD, unstable angina, Graves’ disease, diabetes, OA, hypertension just to name a few. I was given so many meds but I only took the heart and hypertension meds and told my doctors to give me 3 mos to work on my health. I immediately started IF , with a 24 hr fast once a week and walk 2- 3 mi on the treadmill almost everyday and also did infrared sauna after each workout,3 mos later I reversed my diabetes and my auto immune disease went into remission, OA doesn’t bother me anymore . Now I’m working on my heart and copd but it’s proving to be a challenge. I’m 58 yo , 5’4, 125 lbs during my first diagnosis. Oh I kinda tweaked my diet a bit too, mostly organic meats, wild caught fish, and veggies all home cooked and stopped using seed oils. Good luck to both of you.
I knew one guy whose Doctor actually suggested he take up smoking! While this was 25 years ago it still was shocking. He was quite overweight. He also was anxious. Maybe his doctor thought smoking might reduce those two issues.
I have also known someone who’s Dr recommended smoking.
I have been interested in your takes on muscle matters in general but I have been thinking for such a common discussion, what does "muscle" actually mean? In CVD discussions, I would expect the muscle I care most about is my heart, to the possible point that heavier people's hearts have to work harder, which is therefore protective? If I'm bench pressing all day and gaining muscle mass, would I be better off climbing stairs and focusing on hitting my max heart rate instead? Should I just pay for the premium content?! ;)
I don't know about that. I have heard that bodybuilders tend to get heart problems, because the drugs they use also affect their heart muscle growth. Bigger isn't always better.
Heavier people's hearts do tend to have to work harder, and in an acute sense, you're right - it helps. However, chronically, it causes the muscle to hypertrophy in a pathologic way and the heart ventricle diminishes, causing heart failure. That said, exercise is an acute stimulus, so all forms of exercise, but especially cardiovascular exercise, helps fight heart disease.
1. Some exercise is better than no exercise.
2. Some resistance training is better than no resistance training.
3. More muscle groups are mostly better than fewer muscle groups.
4. Optimal varies by the individual, including age and current fitness, and also what goal you're trying to optimize (attracting a mate, current functionality, short-term mortality, long-term mortality).
@@PhysionicI am glad to hear you say that, as some fitness influencers who mostly lift weight like to say you can get just as good a cardiovascular workout lifting. I guess they worry about people shirking I’ll weightlifting in favor of aerobic work, but I know you’re not suggesting that.
I am curious as to why potentially having more muscle mass would prevent heart disease?
How many "studies" compare apples and oranges and don't reflect an individual person's risk
I struggle with losing weight, but have lifted weights for decades and have a lot of muscle mass. My GP, a nurse practitioner (rural area, bad insurance) only looks at my BMI as labels me obese (I don't think I look obese, not typical obese... more like the bigger football players and not as fat as most powerlifters). I can never seem to find, or receive any good information about my risks that don't assume a sedentary and junk food (I eat pretty healthy, not perfect (who is?), but rarely eat junk and always eat vegetables) diet, based on BMI and age (52), suggesting I could drop of a heart attack at any minute... I feels as healthy now, as at 30, maybe healthier. Our healthcare system is incredibly frustrating.
You should get a body composition done as that would be the only real way to know if you are overfat or not. At 52, your body fat should be lower than 21%.
ok you just started to answer it
Bad ass channel. Do a video on marijuana is it good for you is is not? Some people say it causes psychosis. I don't know what to think but I think it's bad.
Would that mean the muscle loss from fasting would also be detrimental?
Fasting should not be dropping muscle unless you're not exercising
what kinds of weight gain? Is that muscle of fat?
I think if you exclude the fat loss benefit, losing weight is bad for the heart. It is compounded by the fact most muscle loss happens by weight loss and then when there is weight gain, not all the muscle gets put back on. It seems it is not lack of activity that leads to muscle loss, but the muscle loss happens in periods of starvation
Heart attacks also cause weight loss
if you don't die you get edoema from the body's stress response, so weight gain.
I believe if one dies they stop losing weight.
I suppose if extreme surprise caused the heart attack one might void their bowels.
Wouldn’t rapid weight loss raise FFA from fat stores?
This is in “old” adults. How old are we talking about? Was the weight loss intentional, i.e. the individuals were over weight and altered their diet to lose weight? Or, as a result of a “slower lifestyle“ due to aging started becoming “frail”? (I am currently observing someone in her 90’s who fits into the latter category. No, it’s not me!) You can see the latter group in many nursing homes. They lose weight because they are no longer interested in eating; they no longer move enough to even get hungry. Similarly, those who intentionally lose weight without at least doing something to maintain muscle mass, as well as eat enough protein to do so, will also encourage frailty.
I think sometimes we forget that the heart is composed of muscle, albeit a different type.
65+
@@Physionic 🤭 I guess I’m old. I keep trying to forget that. Futile, I know. 😞
People with diabetes loose weight. May be they are getting biased by choosing diabetic people.
april fool day video surely
Smoking is good for you though. It helps reduce risks of various cancers and improves heart disease outcomes (Now read that again but keep in mind what the date is)
Joking aside
Smoking is beneficial in Inflammatory Bowel Disease
About 4 cigarettes a day
Do you remember during the pandemic, France was the first country to notice, that smokers didn't get covid.
Would the muscle loss be the most likely explanation for the study making rounds in the media claiming intermittent fasting increase heart attacks by 90%?
probably a major factor , muscle loss. Yoyo dieting is considered bad , fat is very necessary , so losing protective fat could be a factor . Most older 90+ people are normal and slim , not many are skinny
I suspect lots of people who tried to lose weight also tanked their protein intake.
Anything else but the elephant in the room
Why are there two "0.7" marks on y-axis? ua-cam.com/video/KM_v-AyU5_w/v-deo.html
Bad scaling software sub-unit. It's carrying to more than one decimal point, but rounding to one decimal point. So, 1.00, .92, .84, .76, .68, .60 rounds to 1, .9, .8, .7, .7, .6
@@Galahad54 ah ... I should have known: my scales are always lying to me too.😋
Yoyo dieting is considered bad , also still waiting for a good fat analysis , probably not yet as not enough studies finding the MOST optimum fat % for an individual especially elderly . It varies by sex , by how body stores it , by type . So is probably quite nuance d. Lower body fat does not always equal better . I would rather 15% BF than 10% , if no known inflammation and low fat % around organs . To protect in times of illness
Fat breaks down into alcohol bases. If Alcohol Dehydrogenases are downregulated, rapid fat loss can cause issues.
Especially if tetrahydrobiopterin is in the wrong oxidation state.
E=MC^2
Mass & energy are the same coin😉
And where do we get our energy from?
Ope, yep, that would be mitochondria..
Personally I would like to know the mitochondrial haplogroups of those involved and a breakdown of their fatty acid consumption.
there is an attack right now on weight loss first was intermittent fasting now its weight loss.
being healthy is bad for the medical industry.
WTF are you talking about
@@MichaelGGarryyou been living under a rock?
And always linked to heart problems.. What else is linked to heart problems, I think it was mandated some time ago?
I actually believe nicotine is good for you.
Not smoking, just nicotine.
lol remember when dr gundry said that smoking is good because of nicotinic acid (nicotinic acid is a form of vitamin B3 called niacin, which has nothing to do with nicotine that's present in cigarretes)
@@andremarques6270 Nicotine raises your IQ, enhances attention, working memory and fine motor skills.
Who wouldn't want that?
Define good for you. Stimulants enhance attention, increase performance and make you loose weight, and increase muscle performance.
I don‘t know though if everybody should take them if they do not need to due to side effects.
On the other hand, caffeine is a stimulant as well, and I do not think it is harmful in normal doses.
@@ZappyOhI agree that it's acutely beneficial for mental performance, but is there any data showing it helps your health long term?
@@noah5291 I don't know of any health benefits besides mental and psychological ... but isn't that enough?
Prolonging life vs. enhancing life. One doesn't exclude the other, from the hall of "good for you".
weight loss cause heart attack.....to the MDs 'cause they lose the munee😂😂
April fools?
If semen is largely made of fat, we'd all be losing weight.
And the elephant in the room is. Yes you guessed it. Talking about elephant and overweight.
First, I am superior to everyone else
Or you're a real no-life? 😉
Share with us your secrets.. How did you become this cool?
@@inverted_real_it_y You just gotta roll with it you know?
I notice at least one character flaw.
💪
Weight-loss is hard.
Makes sense
Weight gain is soft!
Intermittent fasting, low carb and a bit of exercise and the fat will melt away. The problem is people think they have to but it is all about wanting to.
OMAD + LOW CARB = EASY
@@inverted_real_it_y Would IF, HCLF same calories, and exercise do the same?
Just do small changes, incrementally, and stick to them. I've lost 50+ pounds a few times. It's not as hard as it looks, it actually gets easier every time. Honestly, I find gaining 50+ pounds harder.
And make sure you explore different strategies until you find the one that works best for you. Low carb, low fat, omad, intermittent fasting: none of those are better than the other options for fast loss, but one of them might suit you best.
lose fat, not weight. try to build/keep muscle while losing visceral fat.
Sarcopenia is bad for you.
But it is April Fool’s Day…
That is why BMI is a poor indicator.
VERHOEVEN... your parents or grandparents are dutch or flemish?
Martian, actually
@@Physionic Cool! I read about them in a book (or more) by Ray Bradbury.
funny@@Physionic
April fool?
When big pharma needs more clients because they stopped buying va c c ines
conspiracy much?
Weight loss + muscle loss = ozempic
You don’t need Ozempic to have that combination, but Ozempic will likely lead to that combination.