Alternative splicing ( mechanism and its regulation )

Поділитися
Вставка
  • Опубліковано 6 чер 2024
  • This video describes the mechanism and regulation of alternative splicing in details .Alternative splicing is a process that enables a messenger RNA (mRNA) to direct synthesis of different protein variants (isoforms) that may have different cellular functions or properties. It occurs by rearranging the pattern of intron and exon elements that are joined by splicing to alter the mRNA coding sequence.

КОМЕНТАРІ • 97

  • @priyadarshinighosh6461
    @priyadarshinighosh6461 3 роки тому +68

    I don't know why people are complaining about your accent, in my opinion the accent was totally fine. Im grateful that you are making videos on such concepts , which are not easily available on UA-cam and that too in a very interesting way.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +7

      please share among friends ,juniors and help me to reach big audience

    • @user-ry1ds3sc8e
      @user-ry1ds3sc8e 2 роки тому +1

      @@animatedbiologywitharpan thanku so much for your great effort ❤️

    • @autf1_6
      @autf1_6 7 місяців тому

      2 niz de hintlisiniz o yüzden olabilir mi bacım

    • @m.a.k354
      @m.a.k354 3 місяці тому

      If he just increases the base of his voice with more stress on words then he sounds like Hrithik Roshan😆lol

  • @mitrassato544
    @mitrassato544 2 роки тому +8

    You explain so well! This is the kind of explanation I'd been waiting for! Thank you so much Arpan! :-)

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Please share my channel link with your friends and help me to reach big audience .

  • @FuzzyCorpsicle
    @FuzzyCorpsicle Рік тому +2

    Thank you so much for the explanation. I just couldn't wrap my head around it.

  • @RishiKumar-zv3lc
    @RishiKumar-zv3lc 2 роки тому +3

    Thankyou sir for explaining this concept!
    I was searching for this since like forever....and you made this really easy to understand ❤️

  • @lectrix8
    @lectrix8 3 роки тому +7

    Taking a genetics class this semester in TX and have found your videos just recently. I'm mad I didn't find them sooner great work. Your plug at the end for your other social media platforms is a little too fast, my daughter's age 9 and 11 always laugh at the end because you noticebly accelerate your speech. Be confident and slow It down. You are offering great value in this videos, no shame in marketing it on all the platforms your on.

  • @aldenconsolver3428
    @aldenconsolver3428 3 роки тому +5

    Excellent enjoyed this a great deal, going to subscribe. Noticed that the user below me in these comments had mentioned your accent - well I'm a Kansan which is considered (along with Nebraska) the standard US accent and I had no problems at all - I would actually be curious to compare your speech patterns to other accents to try and see how you are able to communicate so well. Considering that I am an elder Kansan with some hearing loss and have no issues with your accent - I would not worry about it if I were you.

  • @rajanpatel4266
    @rajanpatel4266 9 місяців тому +1

    Medical student in America here! Thank you for helpfully elucidating the mechanisms of alternative splicing

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  9 місяців тому

      I have a request, please share my channel link in your med school group. I am really trying to reach out diverse audiance. However I am unable to reach out to broad audiance , so I would be greatful if you can help.

  • @fatimagenetics
    @fatimagenetics 11 місяців тому +1

    appreciating you knowledge and efforts for this video.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  11 місяців тому

      Please support our channel by using super thanks. Your 2$ donation would give us motivation to do more. Super thanks option is present below any of my videos, a heart sign with $ in it.

  • @paturulekharamani9710
    @paturulekharamani9710 Рік тому +1

    Its a great lecture..complex topic , explained in a very very simple way.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      Please share my channel link with your friends and help me to reach big audiance. Also don't forget to checkout entire molecular biology playlist in my channel

  • @awesomeblossom949
    @awesomeblossom949 3 роки тому +1

    This is so helpful, thank you!!

  • @AndriCloud
    @AndriCloud 5 місяців тому +1

    finally, i understand why the similarity of genome between creatures can produce different creatures. because of the different gene expression of the protein-coding and regulatory gene. this alternative splicing machinary along with other epigenetic technique play huge role in the differences

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 місяців тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @arijitbasak9241
    @arijitbasak9241 3 роки тому +2

    Your teaching procedure is great.. Thanks a ton.. You got a new subscriber.. 😇❤

  • @Cruck10
    @Cruck10 Рік тому +1

    Thanks this was a great explanation.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому +1

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Small contribution like Rs50/100 means a lot for us.

  • @arupkumardas7253
    @arupkumardas7253 3 роки тому

    Thank you completely understand

  • @grashmasadan1544
    @grashmasadan1544 2 роки тому +1

    Ur vedios are super useful... Thanks... Keep going...

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +1

      Please share my channel link with your friends and help me to reach big audience. Lots of love from India

  • @VDuongHD
    @VDuongHD 3 роки тому +1

    Great video!

  • @minaltariq1191
    @minaltariq1191 3 роки тому +2

    Is troponin refers to tropomyosin gene ? Or if not so what will be the answer of alternative splicing in alpha tropomyosin gene ?

  • @simrankaur1531
    @simrankaur1531 3 роки тому +1

    Well explained sir
    Great video 👏👏👏

  • @rosecaliu2730
    @rosecaliu2730 Рік тому +2

    Thank you very much 🥺💕

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      Please support my channel via super thanks. Your small contribution like 1$ means a lot for us. The super thanks option is present at the lower right corner of any video, a heart sign with $ in it.

  • @nabilamashnoon7092
    @nabilamashnoon7092 3 роки тому +1

    Hey! I really enjoy watching your videos. I have a question: when splicing occurs, are the introns mistakenly included in the mature mRNA? if yes then it causes mutation right? what repair mechanisms are carried out to avoid this problem?

  • @sogolforghani8093
    @sogolforghani8093 3 роки тому

    thank you. it was really helpful

  • @joannevanessavargas5879
    @joannevanessavargas5879 2 роки тому +1

    Thank you!!!!!

  • @nesagolestani4545
    @nesagolestani4545 Рік тому +1

    Im persian but i undrestand more than what i have been read on internet thx.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому +1

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.

  • @user-vr7fd3nd6x
    @user-vr7fd3nd6x 3 роки тому +2

    It is very informative video!! Is it possible to get the some of your illustration for using academic speech in univ. with your paper or youtube citation?

  • @somyagoyal4844
    @somyagoyal4844 3 роки тому +3

    Very informative video. But I have a question : When the activator is in Exon (Exon splicing enhancer or ESE), then it leads to exon inclusion or exon exclusion????

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      the mechanism is complex and debated the following review would give you a nice idea sci-hub.tw/10.1016/s0968-0004(00)01549-8

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      Maybe I can discuss this topic later in a video

  • @venuskataria5230
    @venuskataria5230 3 роки тому +1

    Thankyou 🤠

  • @Ayeshakalam
    @Ayeshakalam 2 роки тому +1

    Thank you bro

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance

  • @fatimagenetics
    @fatimagenetics 11 місяців тому +1

    its my first time to watch your video, its very informative, will you have or made such video on intronic mutations or how to solve intronic mutations in wet lab

  • @twinkle9442
    @twinkle9442 Рік тому +1

    Thank, sir

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @riyabatra6013
    @riyabatra6013 2 роки тому +1

    Thank you

  • @saimas_craftastic_world
    @saimas_craftastic_world 2 роки тому +1

    Thanku so much.......

  • @DrVineetSharma
    @DrVineetSharma 2 роки тому +1

    Which software you use to make ur presentation?. It's inspiring

  • @ishas.7508
    @ishas.7508 Рік тому +1

    which software do you use to draw diagrams

  • @atullokhande8339
    @atullokhande8339 2 роки тому +1

    Thanks sir 👍🤞

  • @welcometosagnicksworld3894
    @welcometosagnicksworld3894 Рік тому +1

    Last example was amazing really dada juat a point mutation make us from chimpanzee into humans

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      Really glad to know that my channel was useful. You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @sompurnapradhan1614
    @sompurnapradhan1614 3 роки тому +2

    Sir which is the best book for developmental biology?

  • @nesagolestani4545
    @nesagolestani4545 Рік тому +1

    Hi , how can i use the typed format of ur conference?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      What is the purpose ?

    • @nesagolestani4545
      @nesagolestani4545 Рік тому

      @@animatedbiologywitharpan a conference for my college

    • @nesagolestani4545
      @nesagolestani4545 Рік тому

      @@animatedbiologywitharpan there is not much information on persian sites
      I need it to translate and use if its possible .is it?

  • @maciejbobiarski
    @maciejbobiarski Рік тому +1

    "She like "That's no coincidence", (uh) "I call that shit God"" - lil dicky (pillow talking 2015)

  • @artisuren5807
    @artisuren5807 2 роки тому +1

    Sir ye video Hindi me mil sakta h kya

  • @sourenpaul2579
    @sourenpaul2579 3 роки тому

    Please try to speak clearly sir
    Or use a better microphone
    It will help us

  • @EdT.-xt6yv
    @EdT.-xt6yv 9 місяців тому +1

    6:30

  • @AureliusSirClasses
    @AureliusSirClasses 3 роки тому +2

    You said +20 time's 1 in First one minute.

  • @innocent8488
    @innocent8488 3 роки тому +1

    So horrible desi accent...

    • @vigneshs5286
      @vigneshs5286 2 роки тому +5

      Do u need accent or alternate splicing concept?

    • @panchaliphukan4501
      @panchaliphukan4501 2 роки тому +2

      Unicorn crafts are you here to advertise your oxford level accent?