Transcription and mRNA processing | Biomolecules | MCAT | Khan Academy

Поділитися
Вставка
  • Опубліковано 24 січ 2025

КОМЕНТАРІ • 349

  • @numannedimayvaz1106
    @numannedimayvaz1106 4 роки тому +337

    this dude is so damn amazing.
    His courses are free PLUS he hasn't any ads in his videos. Much Respect for this guy!

    • @mello-by
      @mello-by 2 роки тому +2

      Khan academy is a non profit that you can donate to

    • @haiyun3251
      @haiyun3251 Рік тому

      Lol mines tc has all her vids in yt monetized 😂 doesn't even show up to class, just ask us to watch 15-18 vids per week

    • @wouldbfarmer2227
      @wouldbfarmer2227 2 місяці тому

      @@haiyun3251 I sporcate binips on weasel unit

  • @sophies8573
    @sophies8573 7 років тому +2285

    This video is supposed to be for high school students and I'm a med student learning the exact same material 😂

    • @leandro6285
      @leandro6285 6 років тому +29

      Same haha

    • @adibsiddiki7409
      @adibsiddiki7409 6 років тому +27

      Sophie Van der Meer Well done on getting in, both of you. I'm hoping to.

    • @muaazbutt9342
      @muaazbutt9342 6 років тому +34

      And i thought i was alone xD

    • @RS6y6
      @RS6y6 6 років тому +74

      I'm a med student too and I wish that this would be enough for the molecular cellbiology exam but it's not even close :'( Great video btw

    • @cpard2d2
      @cpard2d2 6 років тому +44

      I´m in a masters program and we´re learning this too. We go a bit deeper with the promoter sequences, transcription factors and the different polymerases but overall, it´s the same XD.

  • @sleepyduck
    @sleepyduck 8 років тому +561

    the fact that you can digest all categories of subjects and then teach is mind boggling!

    • @ToksNation
      @ToksNation 8 років тому +5

      I know right

    • @itsamemarioanne
      @itsamemarioanne 5 років тому +15

      YYYEEESSS! Sal is a gift for all of us x

    • @jeromeyklein8838
      @jeromeyklein8838 4 роки тому +2

      Maybe he just reads from a script?

    • @Luka1180
      @Luka1180 4 роки тому +16

      @@jeromeyklein8838 Well, he did get a Bachelor of Science from MIT...

    • @notwork2087
      @notwork2087 4 роки тому

      @@jeromeyklein8838 GFY

  • @unclelelax8341
    @unclelelax8341 5 років тому +263

    10 mins lecture > 5 hours lecture

  • @nancygutierrez4856
    @nancygutierrez4856 5 років тому +88

    I have no idea how you taught me something I've been studying for two weeks in 10 minutes and I understood perfectly. I wish you were my professor! Keep it up for the pre-med students please!!!

  • @kyloxd2700
    @kyloxd2700 6 років тому +22

    Anyone else feel the passion in his voice when he talks about these said topics?

  • @Devilsfannumber30
    @Devilsfannumber30 6 років тому +182

    if anyone wanted to know:
    spliceosomes​ are what cut out sections from the RNA strand to remove the introns and leave the exons

  • @janetchiang5658
    @janetchiang5658 8 років тому +232

    it's so weird how you always upload topics about exactly what i'm learning in class!

    • @Chef10245
      @Chef10245 6 років тому +6

      advanced biology/ chemistry topics don't change often so it would make sense

    • @saniwada
      @saniwada 5 років тому +4

      The AP bio and AP chem cuirculum dont really change or varry much school to school

    • @kennarajora6532
      @kennarajora6532 3 роки тому +1

      it makes sense he would change his upload topic schedule to coincide with what kids are learning in class.

  • @smol_chilli_pepper
    @smol_chilli_pepper 3 роки тому +8

    I never imagined that one day Khan Academy videos would become so nostalgic to me

  • @rubyyxlc3936
    @rubyyxlc3936 6 років тому +9

    I wish I would have found this while I was in microbiology, You explained in ten minutes what I couldn't even get from tutoring.

  • @salihatintin5807
    @salihatintin5807 2 місяці тому +1

    While this video was shared long time ago but still sooo benefical for biology students at college. This man literally the teacher all over the world

  • @angiemihalas2319
    @angiemihalas2319 4 роки тому

    5:55-6:27 nothing you need to take notes on, but the reminder we all need! biology is amazing.

  • @FreeWaves9
    @FreeWaves9 2 роки тому +2

    This man is single-handedly carrying the US education system

  • @toddsecor288
    @toddsecor288 6 років тому +3

    This person has helped me better understand chemistry, trigonometry, calculus, and now biology. He is truly amazing. He should be the dean of MIT.

  • @deathhog4409
    @deathhog4409 Рік тому +1

    6 years and this still save lives...

  • @shinysunglasses3617
    @shinysunglasses3617 6 років тому +9

    This is amazing! I found it hard to understand in class because of how shallow it was, but with more details it makes perfect sense! Thanks a lot.

    • @yankeyaya1673
      @yankeyaya1673 2 роки тому

      same, this video is very clear o.O

  • @Testimonyofabutterfly
    @Testimonyofabutterfly 3 роки тому +5

    this was super helpful for learning this process! I am in awe of the creator God and his ability to make such a complex and beautiful process within such a small structure!!! Praise Jesus

  • @astrovation3281
    @astrovation3281 2 роки тому +2

    I like how you don't just pass on the material but also pass on the passion

  • @JorgeRamos-xw6dy
    @JorgeRamos-xw6dy 4 роки тому +10

    Wonderful! I'm getting my UA-cam degree. I navigate from MIT to Harvard to UC Berkeley etc...all for free lol.
    I wish this were around when I went to school. Thank you for the wonderful videos.

  • @sarahfalcone8716
    @sarahfalcone8716 5 років тому +12

    This helped me a lot to understand the processes in the different cells. Thank you a lot!

  • @djennings-DDS
    @djennings-DDS 7 років тому +13

    Great video - thank you. I liked the very clear explanation of Ribosomal RNA (that it doesn't need anything else to code, compared to the DNA where it needs Helicase, RNA Primers, Ligase, etc.) I also really enjoyed learning about the difference between the mRNA in prokaryotes vs. Eukaryotes. It's interesing that the Introns do not have a specific purpose, so the mRNA, is made up of what's left over after the splicing takes place (exons) of that "pre- mRNA".
    Again - I greatly enjoyed this video, thank you!

    • @aplus1080
      @aplus1080 Рік тому +1

      There is no dead weight in nature. I'm curious to see the mystery of introns resolved.

    • @djennings-DDS
      @djennings-DDS Рік тому

      @@aplus1080 I’ve pretty much forgotten everything about RNA and introns

  • @anuradhawijethunga5880
    @anuradhawijethunga5880 3 роки тому +5

    This was really helpful for my last minute exam preparations ❤️❤️❤️ If it wasn't for youtube, I would've failed my uni exams.

  • @cutieinahat4267
    @cutieinahat4267 8 років тому +42

    thanks for my marks khan-academy!

  • @cristianalima6623
    @cristianalima6623 5 років тому +5

    I wish everything good for you, you just saved my exam! Thank you!

  • @mansiraja2623
    @mansiraja2623 6 років тому +3

    Givee meee your handwriting 😻😻😻 and you actually have the capability of pinnng whatever you teach into my head!!

  • @rafiamushal83
    @rafiamushal83 5 років тому +3

    This was so helpful for my university genetics class! thank you!

  • @spxtfxre1
    @spxtfxre1 6 років тому +5

    Mr. Khan, you seem like an awesome human being to me. I really wish you could coach me in person. I got only 16 days left before my 12th grade final examinations start. Thanks a lot for doing what you're doing. That's really great work. Keep it up. I will donate when I am able to. ❤❤

    • @Malak.A.Mudallah
      @Malak.A.Mudallah 2 роки тому

      Me too as a fresh 12th grade student

    • @Gtwiwhwidyjw_2792
      @Gtwiwhwidyjw_2792 11 місяців тому

      His cousins actually prefer him in videos than him in person, maybe it's the system that allows him to be as good as a teacher he is today :)

  • @alltup8347
    @alltup8347 4 роки тому +8

    I’m literally watching this before my exam please wish me luck

    • @5tar-kat
      @5tar-kat 4 роки тому +2

      what did you get?

    • @alltup8347
      @alltup8347 4 роки тому +3

      @@5tar-kat 34/50

    • @5tar-kat
      @5tar-kat 4 роки тому +3

      I got a 75%. I hate biology 😂

  • @saiamitchaddha5525
    @saiamitchaddha5525 4 роки тому +1

    God Is Great, May God Bless them all and you all and your families

  • @silvanaban5797
    @silvanaban5797 6 років тому +10

    Thank you for this. This was extremely helpful!

  • @deboisdead
    @deboisdead 2 роки тому

    honestly as a hon bio student you save my life thank you

  • @김소혜-s5e
    @김소혜-s5e 6 років тому +1

    I'm Korean university student. This explainment helps for Test. Thanks.

  • @TomDavis95
    @TomDavis95 8 років тому +16

    Important to note that in eukaryotes the pre-mRNA processing occurs co-transcriptionally and not post-transcriptionally!

  • @tutik234
    @tutik234 Рік тому

    This video is very well done. Thank you I understood everything. I'm 14 and you explained it very well. ❤

  • @allysonperez5241
    @allysonperez5241 Рік тому

    I love how you get excited about the material. Makes us students much more engaged and excited too. Endless thank yous Sal!!

  • @tulliachampney4713
    @tulliachampney4713 3 роки тому

    love that my professor for my 400 level biochem class assigned us to watch this video

  • @m.a.shahid4927
    @m.a.shahid4927 8 років тому +1

    RIP for Medved's exam, but this video made it much easier. Thanks and keep it up bro!

  • @sciencenerd7639
    @sciencenerd7639 Рік тому

    turns out helicases are involved in transcription after all
    still a great video, keep up the good work Khan Academy, thanks!

  • @owenbartrop8963
    @owenbartrop8963 3 роки тому

    Trust Khan Academy to provide more information than my government :D Thank you Sal, you're a real legend.

  • @chelsieb.593
    @chelsieb.593 3 роки тому

    i don't know how many times throughout my biology career, I've had to rewatch this video

  • @tomkrys3331
    @tomkrys3331 4 роки тому +1

    You should always remember that Biology is amazing. Yeah man it really is!!

  • @bonedoggle
    @bonedoggle 4 роки тому +3

    i learn more from sal than i do from my own professors

  • @mlggirl524
    @mlggirl524 8 років тому +11

    Does anyone know if there is a way to get a print out of the diagrams and pictures he shows. The way he explains all the processes with those visuals really help!

    • @seabass324
      @seabass324 5 років тому +2

      you can always screenshot and crop into word doc instantly :)

  • @fmsenga
    @fmsenga 7 років тому +1

    Thank you for this tutorial...harpers is quite tedious to understand...this helps a lot

  • @sarahholland5980
    @sarahholland5980 4 роки тому

    a whole lecture made ultra-clear in 10 minutes. thank you!!!

  • @Ash-zb7bu
    @Ash-zb7bu 6 років тому +1

    thank you, khan academy, once again for saving my biology grade

  • @mrburns805
    @mrburns805 7 років тому

    This dude seriously has a video for everything

  • @adrienne2838
    @adrienne2838 2 роки тому

    i rememver watching this in high school and now im in my gap years. and im. still watching this

  • @yourfuturedocburenbeiya
    @yourfuturedocburenbeiya 4 роки тому +1

    Thank you so much for this video!! You're the best! Your handwriting is nice and the way you explain it is so much more interesting. I always have more appreciation of what we're learning because of the way you teach it in these KA Videos.

  • @memomemo7643
    @memomemo7643 5 років тому +3

    Thank you soo much that was an 1.30 h lecture of nonsense that u just turned into the most interesting and understandable information in 10.24 mins

  • @mdijkman9386
    @mdijkman9386 4 роки тому +3

    Since this video has been uploaded one thing has been discovered. In termination, right after the hairpin is formed a bunch of Adenine's are present in the DNA, this makes it so that A lot Uracil's are transcribed. The bond between A en U (also T) is quite weak, with only 2 hydrogen bonds formed. So the pre-mRNA falls off.

  • @ilove0918
    @ilove0918 3 роки тому

    you should upload more of DNA/RNA in depth processes!!

  • @omarsalama1375
    @omarsalama1375 3 роки тому

    Allah who made this incredible staff..

  • @tonyi4677
    @tonyi4677 4 роки тому +1

    Thank you so much for the clear and "easy to understand" explanation.

  • @momin665
    @momin665 2 роки тому

    Amazing sir and
    made my day God bless you

  • @kuensedn1529
    @kuensedn1529 6 років тому +2

    2 yrs later i watch this once again! :))

  • @علي..الشنطه-ن5ي
    @علي..الشنطه-ن5ي Рік тому

    Thanks for the great explanation 🌹

  • @why6207
    @why6207 6 років тому

    You are the best teacher I have ever seen

  • @TainzeNande
    @TainzeNande 3 місяці тому

    Wow he made it so simple

  • @dhivyaseker3378
    @dhivyaseker3378 6 років тому +1

    This video is really helpful The way he teach is very understandable Thank you so much. It helped me a lot.

  • @michael_alan
    @michael_alan 3 роки тому

    You are very clear in your teaching Many thanks!

  • @charlotte-xd4mq
    @charlotte-xd4mq 2 роки тому

    THIS is what's helping me to keep up with my bio class 😂

  • @fatimahyamani9241
    @fatimahyamani9241 4 роки тому

    Thanks a lot, that’s what I need ♥️♥️♥️♥️

  • @Alaska-Med
    @Alaska-Med 2 роки тому

    You’re amazing thank you teaching us all😁

  • @atheeri7286
    @atheeri7286 8 років тому +1

    5:28
    The RNA being transcripted has the same sequence as the coding strand (with the Uracil replacing Thymine), BUT they don't have "the same information".
    If the coding strand were being transcribed here, it'll give a different RNA sequence, therefore a different order of codons, which eventually gives different amino acids (different protein). So yeah, not the same information =)

  • @averagestudent5222
    @averagestudent5222 Рік тому

    With all these videos I don't think its necessary to go to school anymore

  • @GodzillaGoesGaga
    @GodzillaGoesGaga 7 років тому +1

    This is absolutely fascinating. Thanks for the great videos.

  • @jessicab6131
    @jessicab6131 2 роки тому

    wish you were my instructor... i love your facination for this.

  • @themoralshow902
    @themoralshow902 4 роки тому +1

    Thanks ❤️
    From 🇱🇰

  • @benward5041
    @benward5041 4 роки тому +2

    sal always makes me feel safe lol

  • @fatemakhan2161
    @fatemakhan2161 2 роки тому

    omg amazing Thanks from very bottom of my heart

  • @ruththomas5667
    @ruththomas5667 Рік тому

    SUCH AN AMAZING VIDEO THANK YOU SO MUCH!!!!!

  • @shotgunner07gaming
    @shotgunner07gaming 3 роки тому

    This recap is just what i needed!

  • @c4sh3w
    @c4sh3w Рік тому

    Could you point out what MCAT stands for and what role it plays in this process?

  • @princetandukar9290
    @princetandukar9290 4 роки тому +20

    Khan academy: You should be in AWE with this!!!
    *Me: YAWNs
    Biology: *am I a joke to you?

  • @clintluna6884
    @clintluna6884 5 років тому

    Love the enthusiasm!! Awesome video! The Audio kept cutting out about every minute or so on my end, not sure if it's just me or anyone else??

  • @brettisaac46
    @brettisaac46 3 роки тому

    So what's keep the Exons from floating away from each other once the introns are spliced?

  • @sherlonsinclair1156
    @sherlonsinclair1156 7 років тому

    Your videos are amazing. Cannot possibly get any simpler. Thank you. You're a life saver.

  • @alandriaglenn3145
    @alandriaglenn3145 2 роки тому

    I am so grateful for your videos! Thank you!

  • @fersiva1
    @fersiva1 7 років тому +1

    Hi Mr Khan, thanks for the explanantion but can you explain on the process on how the cap and tail is added and their purpose in conversion of pre mRNA to mRNA?

  • @FamineNH
    @FamineNH 6 років тому +3

    Gona kill my bio final. Thanks for the videos bro they've helped me so much. Very confident I'm going to get the A I need in this course!

  • @mihirmakwana9012
    @mihirmakwana9012 4 роки тому

    M in 1st year medicine and m watching this coz it's very helpful 🤪😅🔥

  • @ElloBoppit
    @ElloBoppit 3 роки тому

    It is mentioned in this video that the RNA Polymerase is more than enough to open the DNA and begin transcription. However, in my Kaplan biochem 2020 MCAT prep booklet it says that RNA Pol II is preceded by helicases & topoisomerases to address unwinding/supercoiling. So both work?

  • @edwardlazo3945
    @edwardlazo3945 3 роки тому

    MAAAAAAAAAN love the way you teach!

  • @sherm7107
    @sherm7107 4 роки тому +4

    Gene editing eugenics, using aborted baby cells and tissues also, GMO nanotech particles

  • @angeefung
    @angeefung 5 років тому +1

    at 5:19 why the T is replaced by U? I thought this happed in translation.

    • @goodnessoverloaded1078
      @goodnessoverloaded1078 5 років тому

      Umm no , I guess you are talking about the anti codon end of tRNA , in all types of RNA the Thymine is replaced with Uracil not only in tRNA but also in mRNA.

  • @ritikasrivastava3840
    @ritikasrivastava3840 2 роки тому

    2:13 writing so that i can see it again

  • @trensza
    @trensza 8 років тому

    Nice. This makes so much sense now

  • @ahmedabdulrhman1358
    @ahmedabdulrhman1358 6 років тому

    realllllllllllllllllllllllllllllllllllllllllly huge thanks, you are great and amazing teacher

  • @evanli9757
    @evanli9757 7 років тому +1

    did you pre-draw all those shapes of ribosomes, DNA, and others?!?!?!?! that's insane

  • @agnestee4261
    @agnestee4261 4 роки тому

    Thank you! That was super helpful and easy to digest!

  • @Goldielopss
    @Goldielopss 8 років тому +9

    I needed this exact video a year ago :'C

  • @tamim-z4l6h
    @tamim-z4l6h 8 років тому

    thank you very much.it helped me a lot for my exam today

  • @jideo4701
    @jideo4701 8 років тому

    Thank you so much! I'm gonna shed a tear.

  • @demetrakaskiri6987
    @demetrakaskiri6987 6 років тому

    thanks for helping on my Biology test!

  • @11194358
    @11194358 3 роки тому

    ''someone like me is going to give you these nice clean narrative'' is funny haha

  • @Jojo-kl6tx
    @Jojo-kl6tx 6 років тому +5

    Awesome video, in general awesome videos. I study Applied Biology and it's great to have your videos and from there read further into the subject. Thanks a lot! (also, this is great for getting an overview since I have no idea how to get all the biology stuff in my head I need to know in three days)

  • @AnnmarieGayle-j5n
    @AnnmarieGayle-j5n Рік тому

    It’s in middle school our school teaches us about kids are born DNA and cancer how to get it how and how it works

  • @radiyatummardiya7835
    @radiyatummardiya7835 3 роки тому

    So , we can say that RNA is single stranded because it transcribed from a single template strand of DNA?

  • @loisbeard8536
    @loisbeard8536 3 роки тому

    Hi, thank you for your hard work, it’s an amazing lesson! But I don’t quite understand the way mRNA develops towards 3’ instead 5’? Thanks