Fischer to Haworth Projection

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  • Опубліковано 6 жов 2024
  • Fischer to Haworth Projection: This video gives an elaborate explanation on how the cyclic Haworth projection is formed from the open chain Fischer projection for both galactose and glucose. More specifically, it builds from the old presentation and comes into its own at 3min 10 seconds giving an elaboration on how (and why) the OH group on carbon 5 bonds with carbon number 1 as opposed to the OH from the 6th carbon. The presentation also explains how to label alpha and beta anomers for both D and L glucose and galactose while also proving a range of examinable questions with model answers. Enjoy :-)

КОМЕНТАРІ • 367

  • @العنزيالعنزي-و6و
    @العنزيالعنزي-و6و 6 місяців тому +23

    By God, the Most High, the Great, you, professor, deserve millions of likes because of this great explanation, the idea of ​​which thousands of teachers were unable to convey.

  • @benklein9008
    @benklein9008 Рік тому +32

    I was struggling horribly with this concept. Never have I felt more able to learn a concept that I have taken hours and hours looking into previously than this. Now every monosaccharide seems to be a breeze when converting to the Haworth projection! Thank you!

  • @deathlokarena8515
    @deathlokarena8515 2 роки тому +52

    I was getting confused in these structures even after studying 'em 3 times from my biology textbook (Chapter Biomolecules)......after watching ur easy and awesome explanations I won't forget them anytime soon!! Thanks a lot Sir!!

  • @stewste4316
    @stewste4316 4 роки тому +16

    totally the best video about Fischer and Haworth Projection currently available on youtube, thank you so much

    • @wondersofchemistry
      @wondersofchemistry  4 роки тому +1

      thanks!

    • @doodoobearlove
      @doodoobearlove 3 роки тому +2

      totally I agree. and no smart talk like other videos try to make chem sounds so complex and enjoy audience suffering something only they know better or explain the unnecessary. this one just facts right to the points and critical clarification that test taker needs to know.

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому +2

      Thank you

  • @reinaci0
    @reinaci0 6 місяців тому +5

    I could cry. I finally think I understand this idea. Thank you so much.

  • @racheloracion1189
    @racheloracion1189 4 роки тому +30

    Thank you for this video, it help me a lot to understand this.

  • @username8701
    @username8701 3 роки тому +4

    Where has this video been all my life!!! I need more of this in all subject areas. Thank you soooo much.

  • @the_wookiees
    @the_wookiees 4 роки тому +14

    So well explained! Love the animations you used to showcase the reaction mechanism

  • @annablueseas
    @annablueseas 14 днів тому

    this is the best explanation of converting fischer to haworth i have ever listened to. thank you so much!

  • @chiara5760
    @chiara5760 4 роки тому +6

    i’ve been watching videos on this all afternoon long but i knew when i saw yours that this was the one haha. thank you for explaining details that are often left out, such as what atoms change their places during the switch to the cyclic form and with what motivation, why it has to be the fifth carbon atom reacting with c1 and why on earth the substitutes on the left have to go on top. will be sending this to all the chem students in my hear. thanks for making this

    • @wondersofchemistry
      @wondersofchemistry  4 роки тому +2

      Hi Chiara, thank you so much for your positive comments. It means a great deal to me. Thanks once again!

  • @roxon6929
    @roxon6929 3 роки тому +1

    I have a very important exam of my life on 3rd October ( the Jee advanced) it can almost make life...
    The video helped me a lot..
    Love from India

  • @pratikshyalamichhane4326
    @pratikshyalamichhane4326 4 роки тому +1

    Before ,I used to choose videos based on views and subscription . But this tutorial changed the way of my perception . Crystal clear about this topic . Thank you for teaching with minute details . Subscribed !!

    • @wondersofchemistry
      @wondersofchemistry  4 роки тому +1

      Thank you for your positive comments. It means a great deal to me :-)

  • @nateriver3541
    @nateriver3541 2 роки тому +2

    Brillant Video made the concept crystal clear. I was struggling with the structure of L Beta Galactopyranose as I was just remembering that if the OH is down then it is alpha. It worked until I met with L structures. Your point about the look at c6 and the anomeric carbon is Brilliant. This made it so much easier. I literally can't stress enough how mindblowing this video is Thank you man really thank you so much.

    • @wondersofchemistry
      @wondersofchemistry  2 роки тому +1

      Hi Nate. Its been a while since i have looked at my youtube channel. What a lovely comment.Thank you so much. I might just start making more videos thanks to you. Regards, MG

  • @kolar06
    @kolar06 Рік тому +1

    I’m at last high school class in Poland. That topic was one of the most important for me and i always had trouble to learn it. After i watched this video i urserstood everything. Thanks a lot!!

  • @leamed7235
    @leamed7235 4 роки тому +7

    Thank you! i'm a french student and it was exactly what i needed

    • @wondersofchemistry
      @wondersofchemistry  4 роки тому +4

      Merci beaucoup. Je suis heureux que vous ayez trouvé ma vidéo utile. Salutations d'Australie!

  • @tanyasaxena3607
    @tanyasaxena3607 3 роки тому +1

    I think this is the best video for understanding fisher's and hawarth's projection.
    After reading many books and papers now finally I'm able to understand this topic because of this wonderful vdo...

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому

      Glad it was helpful! and thanks for your positive comments :-)

  • @deniseligores3745
    @deniseligores3745 4 роки тому +14

    Thank you for teaching this! I’ve been having a hard time with this for daaays😅

    • @wondersofchemistry
      @wondersofchemistry  4 роки тому +1

      Thanks Denise. How exactly did the video help you in your understanding? Just keen to know which segments of the video you found to be of most benefit. This will help me in how i create my future videos. Thank you :-)

    • @deniseligores3745
      @deniseligores3745 4 роки тому

      Hi! It helped me understand how the structure was formed because you taught it step by step, and also how the different atoms interact with each other 😊

  • @SMILE-iq6vo
    @SMILE-iq6vo 3 роки тому +1

    I can't describe your work qulification it is so legendly

  • @sofia_m762
    @sofia_m762 3 роки тому +1

    Holy smokes. This is one of the best, if not the best, video i've seen. It made me understand so well, and it answered all my questions. Thank you so much.

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому

      Thanks Sofia. What a lovely thing to say. It is much appreciated. Hope all is well on your side of the world. Regards, Wonders Of Chemistry :-)

  • @TheDacker57
    @TheDacker57 3 роки тому +3

    THANK YOU! Nowhere in my textbook did it make sense like it did here.

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому

      No worries Jake. Thats great that video helped so much!! Feel frre to share with your fellow students :-)

  • @Mahi-eh2ps
    @Mahi-eh2ps 4 роки тому +1

    Great work sir , I am from INDIA , so helpful video , i was struggling with this stuff . But you made it very simple and clear .

  • @yutongdai8645
    @yutongdai8645 Рік тому +2

    This has been such an helpful video! I finally understood what substituents to look at when determining whether they are on the same side or the opposite side of the ring. One caveat I would have though, is alpha is on the SAME side, while beta sugar is on OPPOSITE side. I think the video might have reversed the two

  • @justtoseegoodthing6856
    @justtoseegoodthing6856 4 роки тому +14

    You literally saved my life with this video, thank you so much !!! In this quarantine i am all by myself with my schoolstuff but this really helped me !! 👏🏻👏🏻👌🏼👍🏻🔥

    • @wondersofchemistry
      @wondersofchemistry  4 роки тому

      Your welcome. Feel free to reach out if there is anything else that you think would be beneficial for a future presentation.

  • @molybdenum20
    @molybdenum20 2 роки тому +1

    Thank you so much! I was looking at my class's powerpoint slides since I typically fall asleep in class and was mega confused. You saved my final exam I think/hope.

  • @luishelfer4204
    @luishelfer4204 4 роки тому +2

    The presentation of the information was spectacular! The drawing and animation were some of the best I've seen on UA-cam. Will be definitely looking into your other videos, keep it up!

  • @ice0714
    @ice0714 3 роки тому +1

    Thank you so much, the video was short and on point, it really saved me a lot of time since I am preparing for uni-entrances

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому

      no worries, its great to hear that my video is assisting you with your preparation for entry into university based education. Good luck with it all. Regards, Wonders of Chemistry.

  • @AnujaAriyaratne
    @AnujaAriyaratne 4 роки тому +3

    Give this man an award

    • @wondersofchemistry
      @wondersofchemistry  4 роки тому

      Thanks Anuja. Your positive comments are much appreciated :-)

  • @teresamontes2542
    @teresamontes2542 3 роки тому +1

    Thank you for your teaching. Way better than on class

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому

      Thanks Teresa. Do you have any other suggestions on what you believe you and your fellow students could benefit from within the realm of biochmistry that i have not already covered on my chanel? Maybe have a chat to your fellow students as well to see what they are struggling with? Regards, Wonders of Chemistry

  • @psychepark291
    @psychepark291 8 місяців тому

    Thankiess for this. I feel so confused when my teacher taught this in class. But with this video, I now understand the topic and I feel so proud with myself.

  • @ACE-dz3kc
    @ACE-dz3kc 4 роки тому +1

    I've been struggling learning this concept ever since online class started. I'm so glad I was able to understand. 😭💕 Thank you so much

  • @Grace-ke3jb
    @Grace-ke3jb 4 роки тому +2

    THANK YOU SO MUCH! i have my orgo final today and my professor didn't really explain how to do this, so thank you for easing my stress about this topic :)

  • @jakobjusinski
    @jakobjusinski 8 місяців тому

    Thanks a lot, now I understand much better after the clear explanation and examples!

  • @nuwanthaherath7388
    @nuwanthaherath7388 3 роки тому +1

    Thank you for the explanation. it's really easy to understand by watching this video!

  • @cristianodimaina2899
    @cristianodimaina2899 3 роки тому +1

    Hello and thank you very much for this explanation, you were very precise and I understood everything! Thanks again, many greetings from Italy

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому +1

      Ciao Cristiano, grazie mille per il tuo messaggio. Sono felice di essere stato di aiuto. Saluti, dall'Australia :-)

  • @aidanlee7000
    @aidanlee7000 8 місяців тому

    THIS VIDEO IS A LIFE SAVER!!!!! Thank you so much for making it easy to understand!!!!!!

  • @JMYaden
    @JMYaden 5 місяців тому

    Thank you so much for sharing your knowledge! Your videos are very clear and easy to follow. Along the way you seem to have a knack for answering questions that might be asked. Very enjoyable. After going back a few times, I was able to pass your final quiz. I look forward to watching the rest of your content! Subscribed!

  • @silviaberger352
    @silviaberger352 Рік тому +1

    SUPERB explanations!

  • @gabrielmakoi3905
    @gabrielmakoi3905 3 роки тому +4

    It’s such an easy-to-understand presentation. Thank you

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому +1

      Thanks for the feedback. I am happy that you found the video useful. Feel free to share with your fellow students :-)

  • @chayenn607
    @chayenn607 6 місяців тому

    You the one that explain every detail thanks!

  • @lilyapurado2698
    @lilyapurado2698 4 роки тому +2

    thank you so much for this video, this made me understand the concept more and also understand fully well how different fisher and haworth projections. You saved my grades! More power and Godbless!

  • @mdabduljaliljalil5335
    @mdabduljaliljalil5335 3 роки тому +1

    Thank you so much sir,i am bangladeshi student, i was some confusion to this topics. Your delivered lacture helps me to understand.

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому

      Hi thank you for your kind words. I am glad the my video helped you understand this concept. Kind Regards, Wonders of Chemistry in Australia

  • @angikbhowmick
    @angikbhowmick 3 роки тому +1

    Many many thanks for this session.

  • @arjunsecondary
    @arjunsecondary 4 роки тому +1

    very good video with the practise at the end. made it much easier to ensure I got the hang of the concept.

  • @lisa.13
    @lisa.13 6 місяців тому

    this video is just perfect. God bless you, thank you so much for uploading on here such a clear explanation of this important part of biochem.

  • @johnsmith-wi2mm
    @johnsmith-wi2mm 10 місяців тому

    oh thank god bless you honestly.. i wasn't even studying chemistry this showed up in my biomolecules unit in bio and the alpha and beta glucose ring structures were bothering me so bad i had to make sense of it before i moved on... thank you!!!!!🙏

    • @johnsmith-wi2mm
      @johnsmith-wi2mm 10 місяців тому

      u truly have a way with clearing all potential doubts a student could have before they could even think to pause and ask LOL

  • @iltafhussain8352
    @iltafhussain8352 3 роки тому

    So much easily explanation with 100% understanding

  • @aasthabajaj7444
    @aasthabajaj7444 4 роки тому +2

    It was so perfectly explained...absolutely got it💓

  • @poutnik9001
    @poutnik9001 3 роки тому +1

    Was a little scared about quality when there was a music at the beginning, but it turned out to be very helpful tutorial! thanks!

  • @btskookiearmy776
    @btskookiearmy776 11 місяців тому

    You made this extremely easily to understand thank you 🙏

  • @manel.w5482
    @manel.w5482 4 роки тому +1

    Thank you very much, I had a hard time with those exercices, but now I'm alright !

  • @allyonightmare
    @allyonightmare 4 роки тому +1

    this is great. turn right 90 degrees! who knew it was that easy? thank you!

  • @Academicallystressedout
    @Academicallystressedout 6 місяців тому

    The only video that made me understand perfectly thank u

  • @marymargaretalmazan9235
    @marymargaretalmazan9235 4 роки тому +1

    thank you. this was helpful beyond measure. more power to you.

  • @mdimrangazi2290
    @mdimrangazi2290 2 роки тому

    Great.. thanks... I was confused in open chain chiaral No 5. here how OH becomes O and how vanished H. Now I'm clear. Because of rotation it happens nicely 🙂. Thank you, sir.

  • @udatchi
    @udatchi 4 роки тому +1

    Amazing video! At around 6:00 however, the H+ does not attack, there is a proton transfer but the lone pair on the oxygen should attack the hydrogen in the end. Thank you so much! I have trouble with stereochem because it gets messy and I had trouble drawing structures in Haworth fashion but I have no trouble now!

    • @wondersofchemistry
      @wondersofchemistry  4 роки тому

      thanks for your feedback :-)

    • @cartwrighteric
      @cartwrighteric 4 роки тому

      lmao I said the same thing to myself. Awesome video though. Helped me understand. Do you have a video for Haworth to chair confirmations?

  • @leahreeseverson531
    @leahreeseverson531 4 роки тому +1

    Thank you so much! Hope you help more students in the future bc u amazin!!!

  • @airsports2012
    @airsports2012 4 роки тому +1

    Great video! Surprised you don't have too many subscribers. You deserve a lot more!!

    • @wondersofchemistry
      @wondersofchemistry  4 роки тому +1

      Thanks Antonio. Your channel looks pretty cool too. Regards, from Wonders of chemistry down under in Australia

  • @lutfiakhan6090
    @lutfiakhan6090 4 роки тому +1

    I could not find the structer of l galactose...but now in this video help me a lot....thx...we want more video....

  • @sheenusharma4514
    @sheenusharma4514 Рік тому

    Very clear concept. You made my life easy.

  • @oxell4925
    @oxell4925 3 роки тому +2

    How do you know if the #5OH group is going to be pointing up or down to form the alpha or beta anomer from the Fischer projection? I can make the Haworth, but it seems to me every fischer projection in this video has been with the #5OH pointing down, so I don't know how to make anything other than the alpha anomer.

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому +2

      Hi Andrew, recall that objective of the OH functional group located on carbon number 5 of the fischer projection it to react and form an intramolecular bond with the aldehyde functional group located on carbon number 1. It is therefore non-existant after the formation of the cyclic structure and therefore has no bearing on whether the newly formed haworth structure is alpha or beta. What you should be focusing on is the relative positions of the CH2OH located on carbon 5 (cyclic structure) and newly formed OH on the anomeric carbon formed on carbon 1 (cyclic structure). If they are opposite sides of the ring (i.e., one facing up while the other is facing down) then you would be looking at the alpha anomer. On the other hand they are on the same side of the ring (both facing up or both facing down) then this would be the beta anomer. Feel free to contact me if you are still struggling with this. Regards, MG :-)

    • @JaneDoe-ob9dr
      @JaneDoe-ob9dr Рік тому

      "I'll be RIGHT DOWN"
      "Left it UP to me"

  • @ADAPTATION7
    @ADAPTATION7 4 роки тому +1

    UA-cam should be the only school for learning quickly.

  • @olan5607
    @olan5607 4 роки тому +1

    Hey im from Poland. My english is so so. But this video is really good so I understand everything. Thank U ❤️

  • @nisrinexf5925
    @nisrinexf5925 3 роки тому +1

    Thank you soooo much sir; this video is exactly what i was searching for.. it is so helpful : )

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому +2

      Thank you for your feedback. I am happy the video helped you :-)

  • @garydunn9418
    @garydunn9418 27 днів тому

    Absolutely well explained.

  • @sandrigomez2828
    @sandrigomez2828 3 роки тому +1

    Thanks so much for this video!! It was so helpful for biochemistry!!!

  • @Linda-yb9lq
    @Linda-yb9lq 4 роки тому +1

    Thank you! Very clear and easy to understand

  • @valentinaparedes435
    @valentinaparedes435 16 днів тому

    Great video, super clear. Thanks!

  • @_JoynalUddin
    @_JoynalUddin 3 роки тому +1

    Thank a heap sir,,,,your presentation is so much excellent,,, i am from Bangladesh

  • @maryemmirza3283
    @maryemmirza3283 Рік тому +1

    Hi tysm this was super helpful. I'm still a little confused in assigning priorities in order to distinguish between the L and D galactose. I don't see how the carbon 6 has a lower priority than the carbon 4 molecule. Would you please be able to elaborate on that. I hope this doesn't sound confusing lol

  • @shreyashah9598
    @shreyashah9598 4 роки тому +1

    oh yes you should do a video on amino acids and peptide bond formation in addition to lipid formation!

    • @wondersofchemistry
      @wondersofchemistry  4 роки тому

      Have a look at my playlist on lipids. ua-cam.com/play/PL5-8kYvBxU3pZEQnYtgAR8CfjF70KKKki.html You will see that i have included how lipids are formed. I will put peptide formation on my action check list :-)

  • @Be-h
    @Be-h 8 місяців тому

    Chemistry is even more interesting with these animation ❤❤

  • @sarouh26214
    @sarouh26214 26 днів тому

    Very helpful for med school students thanks a lot !

  • @athiba5945
    @athiba5945 3 роки тому +1

    Amazing explanation.

  • @neyofan123
    @neyofan123 4 роки тому +1

    This video is gold much thanks

  • @siddhantjakhotiya3211
    @siddhantjakhotiya3211 3 роки тому

    Thanks a lot, the definition about alpha and beta helped me in dealing with questions based upon Haworth Projections of L carbohydrates

  • @reganhoppe5513
    @reganhoppe5513 3 роки тому +1

    This was SO helpful-- thank you so much!!

  • @srijahnavi3320
    @srijahnavi3320 2 роки тому +1

    you are a life saver, thanks a lot

  • @cherylannepaculba4592
    @cherylannepaculba4592 2 роки тому

    Thank you so much sir for posting this it is really a big help for me.

  • @ichrak8750
    @ichrak8750 4 роки тому +3

    Thank you so much you save my life😊😊❤️

  • @dimanews8579
    @dimanews8579 4 роки тому +1

    U re so creative in your videos thank u so much

  • @johnx5k
    @johnx5k 9 місяців тому

    Wow really good. You just won another subscriber. Thank you sir

  • @laudiavrskaa1124
    @laudiavrskaa1124 3 роки тому +1

    Nice video, thanks for the explanations👌

  • @imthemapimthemap
    @imthemapimthemap 2 роки тому

    This was very helpful and succinct. Thank you

  • @hanaaktyman234
    @hanaaktyman234 3 роки тому +1

    Awesome
    Makes it so clear and easy💓💓

  • @sushmitamaeleones-coballes5930
    @sushmitamaeleones-coballes5930 3 роки тому +1

    Thank you! You make it easy to understand :)

  • @thomasmuller-h8q
    @thomasmuller-h8q 10 місяців тому

    I was really struggling with that thank you .

  • @erikaacx3425
    @erikaacx3425 3 роки тому +1

    this video was so helpful! Thank you so so much!!!

  • @MauricioOrnelas-zx8qv
    @MauricioOrnelas-zx8qv Рік тому

    This explains it so well thank you!!!!

  • @ayishaharuna7347
    @ayishaharuna7347 Рік тому +1

    Sir please we would be happy if you give a very detailed video on the formation of acetal and hemiacetal mechanism
    acetal and hemiketal mechanism.

  • @AndreannaFaithR.TAMBONG
    @AndreannaFaithR.TAMBONG 7 місяців тому

    Thank you so much! This video is really helpful.

  • @preetamjoshi9259
    @preetamjoshi9259 3 роки тому

    Excellent explanation 👍 thanks a lot

  • @snehasiva6579
    @snehasiva6579 3 роки тому +1

    Super explanation sir I am from India....

    • @wondersofchemistry
      @wondersofchemistry  3 роки тому

      Thank you for your positive comment. Regards, Wonders of Chemistry in Australia.

  • @IyedFriendzone
    @IyedFriendzone 3 роки тому +1

    Thanks for the explanation

  • @doodoobearlove
    @doodoobearlove 3 роки тому +1

    explain it all without me even asking~~ thank you much i been wondering in my textbook why keep mentioned there is one more increasing * C after ring form and i been search which one lol now i see the whole meaning for this term and alpha beta clarification as well.

  • @JaneDoe-ob9dr
    @JaneDoe-ob9dr Рік тому

    Pneumonic to memorize placement "I'll be RIGHT down" put the function group down in Haworths projection.
    "They Left it UP to me" put the function group up :)

  • @incredibleizu4
    @incredibleizu4 2 роки тому

    Thanks a lot for this clear explanation!!

  • @shenjier8060
    @shenjier8060 2 роки тому

    questions:1. Why do you stick to the right-down left-up rule? Can you explain geometrically? 2. Why can you rotate the three groups around the 5 carbon either clockwise or anti clockwise? Isn’t it supposed to be a strong bond in a ring? In reality, the three substituents are even in the same plane? How can you rotate? Wouldn’t it affect the other parts of the ring structure?

  • @idissolvebutirecrystallize8410
    @idissolvebutirecrystallize8410 10 місяців тому

    Wonderful explanation video thank you very much

  • @experimentandexplore4757
    @experimentandexplore4757 3 роки тому

    Thanks for this video..the concept is crystal clear....👍👍👍👍

  • @NaseemAkhter-dy4hd
    @NaseemAkhter-dy4hd Рік тому

    Best explanation ever😊😊😊