Fischer to Haworth shortcut for Glucose and Fructose

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  • Опубліковано 25 гру 2024

КОМЕНТАРІ • 28

  • @GaverMote
    @GaverMote 14 днів тому

    iam from iraq this is in ❤University of Kufa. I searched very hard to find someone talking about this topic. Thank you very much. I feel that I understand the topic a little

    • @Leah4sciMCAT
      @Leah4sciMCAT  6 днів тому

      I'm glad I was able to fill that gap for you!

  • @fatts96
    @fatts96 2 місяці тому +7

    amazing explanation, u saved me once again!

  • @SucpwBcosbsv
    @SucpwBcosbsv 2 місяці тому +3

    In min 0:52
    It isn’t enough to put the last chiral carbon’s alcohol on the left for L-glucose (and other sugars), you have to change all the alcohols to their respective opposite side. If not then you will get a different sugar (an epimer in 2,3,4 of L-glucose, not L-glucose)
    Same problem for fructose

    • @Leah4sciMCAT
      @Leah4sciMCAT  2 місяці тому +5

      Oh my goodness you are right. I don't know how I didn't know this for over a decade teaching this. Thank you so much for pointing it out. Mind blown 🤯

  • @maximilliansaar5512
    @maximilliansaar5512 2 місяці тому +3

    Perfekt erklärt!
    Vielen Dank

  • @ursamajor5744
    @ursamajor5744 7 місяців тому +3

    Is it because D-glucose’s hydroxyl groups are in equatorial position, so it is more stable in that conformation?

  • @miladabdolahzadeh8473
    @miladabdolahzadeh8473 Місяць тому +1

    I have a question, I'm studying veterinary biochemistry and my professor drew the haworth projection with the first carbon on on the left part of the pyran and the c6 down , is he wrong or this is another way of showing it?

  • @ShikahAlmuharif
    @ShikahAlmuharif 3 місяці тому

    This really helps me thank u sm ❤

  • @timecode37
    @timecode37 15 днів тому

    Could it be that the first skeletal formula for D-Glucose isn't quite right? My Fischer projection ends up with all the hydroxyl groups on the right side. If you compare it with the picture on wikipedia, the skeletal structures for D-Glucose don't match. When doing the projection starting from the skeletal structure from wikipedia, the fischer projection matches the one in the video. Can someone tell me what i'm doing wrong?

    • @Leah4sciMCAT
      @Leah4sciMCAT  13 днів тому +1

      Yup, I've been teaching this for well over a decade and only JUST learned that I've know and taught this wrong all along!! I will be redoing this video 🤦🤦🤦

  • @mistyor3754
    @mistyor3754 2 місяці тому

    Hiii teacher , I’m a bit curious about where does the blue OH comes from ?

    • @Leah4sciMCAT
      @Leah4sciMCAT  2 місяці тому +1

      Great question! The blue oxygen is the aldehyde oxygen in the Fischer projection of glucose. It has been converted into an alcohol group in the Haworth.

  • @kroliia3116
    @kroliia3116 5 місяців тому

    What happens to the purple “H” that’s attached to the red “O” that attacks?

    • @Leah4sciMCAT
      @Leah4sciMCAT  5 місяців тому +3

      Good question! The red "O" becomes deprotonated in solution and loses that purple "H". It is no longer a part of the structure when glucose is drawn as a Haworth projection.

  • @NforAbanda-b4w
    @NforAbanda-b4w 15 днів тому

    Why is glucose called D or L glucose

    • @Leah4sciMCAT
      @Leah4sciMCAT  13 днів тому

      The D and L have to do with stereochemistry of the molecule

  • @ppnugget346
    @ppnugget346 Місяць тому +4

    I dont understand it at all imma fail so hard

    • @Leah4sciMCAT
      @Leah4sciMCAT  Місяць тому

      Oh no, I'm so sorry! When do you plan to take the MCAT?

    • @mimi1506.
      @mimi1506. 28 днів тому +1

      Same dude, same...

    • @ppnugget346
      @ppnugget346 28 днів тому +1

      @@Leah4sciMCAT MCAT??? im in the 11th grade
      I got 58% on the bio test btw (im in belgium so its a pass)

    • @sn-bo3un
      @sn-bo3un 15 днів тому

      That’s crazy I’m learning this as a 24 year old in university organic chem 2

  • @BenjaminMakurAnyaar
    @BenjaminMakurAnyaar 25 днів тому +1

    Look how fast you're!!!😢

    • @Leah4sciMCAT
      @Leah4sciMCAT  21 день тому +1

      I hope you found the video helpful!