M&M Clips: Hamilton Describes Ayahuasca vs. Pharmahuasca

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  • Опубліковано 8 вер 2024
  • Hamilton Morris describes the difference between ayahuasca and pharmahuasca, which are orally active forms of the potent psychedelic drug, DMT.
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    About Nick Jikomes:
    Nick is a neuroscientist and podcast host. He is currently Director of Science & Innovation at Leafly, the world's largest cannabis information resource. He received a Ph.D. in Neuroscience from Harvard University and a B.S. in Genetics from the University of Wisconsin-Madison.

КОМЕНТАРІ • 41

  • @MindAndMatter
    @MindAndMatter  3 роки тому +8

    All M&M content is available on Substack. I mainly respond to questions & comments on that channel:
    [ mindandmatter.substack.com ]
    If you enjoy M&M content and want to provide further support, read this:
    [ mindandmatter.substack.com/p/how-to-support-mind-and-matter ]

  • @jessewolgamott2319
    @jessewolgamott2319 3 роки тому +78

    History will look fondly upon Hamilton. Thank you for sharing your knowledge.

  • @azreal629
    @azreal629 3 роки тому +15

    Hi I really enjoyed this episode, I only just discovered your podcast yesterday and I immediately subscribed since you have such great content. I only wanted to ask one thing, are there transcripts of the episodes anywhere? I’ve been researching some of the things Hamilton mentioned and I wanted to make sure I have the spelling right. Transcriptions for podcasts are always a lifesaver since I write so many notes lol. And unfortunately Google’s auto captions rarely capture all the words accurately.

    • @MindAndMatter
      @MindAndMatter  3 роки тому +1

      Don't currently have transcripts - sorry!

  • @nikiholland5010
    @nikiholland5010 3 роки тому +8

    Physical reaction to Ayahuasca varies with everyone. The psycho-social “setting” also plays a role in how one responds to Ayahuasca. Not everyone has an adverse physical reaction to it.

  • @naftalibendavid
    @naftalibendavid 2 роки тому +7

    Dose is the key. Paracelsus said it first but Hamilton keeps the tradition.

    • @Meta-Drew
      @Meta-Drew Рік тому +1

      My man out here seriously referencing Paracelsus, haven't heard him referenced since school. Our teacher was so nutty we even had to memorize the history in our toxicology class

    • @naftalibendavid
      @naftalibendavid Рік тому +1

      @@Meta-Drew I teach a comparable class and tip my hat to you and your instructor.

  • @atutor1
    @atutor1 3 роки тому +9

    This video deserves more views

  • @victoradams3748
    @victoradams3748 3 роки тому +4

    I've personally done pharmahuasca plenty of times but I've never actually done ayahuasca. When I talk to people who have they always complain about the plant alkaloids. I think people prefer pure orally active crystals. Pluss you know you're getting something pure. Dmt and Syrian rue can both be recrystalized. so if you think about it pharmahuasca is logically the best option. Not saying ayahuasca is bad but it can be a little intimidating for a lot of people and almost impossible to find for most.

    • @Rscapeextreme447
      @Rscapeextreme447 Рік тому

      However pharma is not ideal as you miss what’s truly important

  • @vincentpenna3089
    @vincentpenna3089 Рік тому +1

    This really interests me and I wanted for the longest time to try pharmahuasca since I drink Ayahuasca ceremonially and felt absolutely nothing

  • @jacobrobinson8892
    @jacobrobinson8892 3 роки тому +4

    Excellent guest choice.

  • @kevinnavarro6612
    @kevinnavarro6612 3 роки тому +11

    So since MAO breakdown sets to in neurotransmitters, and DMT isn’t active orally because it gets broken down, you need to take an MAOI so the DMT passes through the gut more easily?

    • @pauldejong145
      @pauldejong145 3 роки тому

      yeh

    • @treedrama
      @treedrama 3 роки тому +6

      Yes essentially the gut destroys DMT unless the MAOI has been consumed

    • @communismisfreedom
      @communismisfreedom 3 роки тому +5

      at all*. DMT undergoes extensive first pass metabolism in the gut

    • @rivermachine2362
      @rivermachine2362 2 роки тому +1

      papaya digestive enzyme chewables, helps increase absorption also !

  • @Psyleidoscope
    @Psyleidoscope Рік тому

    hint: perform an extraction on the b. caapi vine first so that you only need to ingest 150-200mg. in this form it is a very beautiful substance.

    • @riseofmerlin3111
      @riseofmerlin3111 Рік тому

      How would you extract caapi vine? Boiling it? And how many grams would you suggest. Usually just use Syrian rue capsules

  • @jasonalexander1753
    @jasonalexander1753 3 роки тому +1

    What is the dosage suggested of mclobamide and how long to wait before taking dmt dose?

  • @pandoraspice1003
    @pandoraspice1003 Рік тому

    Aya has worked for patients and shamen in Central and Southern Americas for thousands of years. It works for them. We cannot expect to steal it and expect to become insta-shamen. But, since the molecule of DMT has already been taken out of the jungle and spread far and wide, I respect the choice of a modern, Western user to want to measure doses out by mgs and use pharmahuasca.

  • @robertbaindourov134
    @robertbaindourov134 2 роки тому +2

    Might try 9mebc as the maoi. going to try 30mg. Which maoi does hamilton recommend?

  • @peter7582
    @peter7582 10 місяців тому +1

    Would methylene blue work as an maoi?

  • @terrencelaitnesba563
    @terrencelaitnesba563 3 роки тому

    good stuff

  • @niklashultkrantz7766
    @niklashultkrantz7766 3 роки тому +2

    Whats the ratio/recipe for pharma

    • @Eva-tg5ep
      @Eva-tg5ep 2 роки тому +2

      Put Caapi extract about half gram or fill cap an eat .50 dmt in another cap an shrooms in another cap I'd start at half gram or under.30 minutes after yellow caapi extract eat dmt cap an boomer cap.

  • @kevinnavarro6612
    @kevinnavarro6612 3 роки тому +5

    Also drugs work differently in different dosages

  • @cjroth6591
    @cjroth6591 3 роки тому +3

    Where can you get moclobemide without a doctor's script?

    • @Elloguvanah
      @Elloguvanah Рік тому

      Any plants with harmaline a
      Alkaloids

    • @Flowerz__
      @Flowerz__ Рік тому

      That’s a great question hahah. Maybe we need to befriend some Europeans ?

  • @Rscapeextreme447
    @Rscapeextreme447 Рік тому +4

    No he’s mostly incorrect, the plant route is far superior. With pharma, it’s more like a digital human experience. With ayah is more so an analog experience connected to nature. You shouldn’t be able to sit and write like on pharma as he explains while on this trip, all of the other chemicals and the nausea and vomiting are part of the full experience. This is one man’s preference.

    • @Meta-Drew
      @Meta-Drew Рік тому +13

      Didn't know someone could be incorrect about their own personal preferences

  • @thomasmastroianni1071
    @thomasmastroianni1071 2 роки тому

    DYRK1a

  • @youtubed2140
    @youtubed2140 2 роки тому +2

    I like turtles