PT268 - Hamilton Morris - PCP, 5 MeO DMT, and the Synthesis of New Psychedelics

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  • Опубліковано 25 жов 2021
  • In this episode, Joe Moore travels to the University of the Sciences in Philadelphia for a rare in-person interview with chemist, filmmaker, science journalist, and go-to media consultant, Hamilton Morris.
    They cover a lot: Hamilton's early realizations of how ill-informed the media was about psychedelics; his time at Vice and how being a journalist gave him a license for curiosity; why he was most interested in covering the substances people were comfortable hating; respectability politics and how only showing what helps the movement is propaganda; Ken Nelson; how we can learn from watching people do salvia on UA-cam; PCP advocate and Process Church alum, Timothy Wyllie; how people attribute more to chemical makeup than their own psychology; and why it's unnecessary (and potentially dangerous) to embrace the narrative that you need to suffer (and do so with a shaman) to truly heal. They talk a lot about his two 5-MeO episodes of Hamilton’s Pharmacopeia (with Hamilton explaining the chemical difference between toad-derived and plant-derived 5-MeO) and they talk about his relationship with Compass Pathways and how it's leading to the creation of many new drugs.
    psychedelicstoday.com/
    / hamiltonmorris

КОМЕНТАРІ • 104

  • @noostrings
    @noostrings 2 роки тому +79

    Hamilton will go down as a revolutionary journalist and chemist. His show is a masterpiece.
    Every night before bed, I search UA-cam for new interviews with Hamilton. His voice is so calming. After years of battling insomnia with pills ect, I no longer need them. His voice does the trick!

    • @melparadise7378
      @melparadise7378 2 роки тому +1

      When you're so into drugs that you BECOME the drugs ♬♫♪◖(●。●)◗♪♫♬

    • @stuntmangMUSIC
      @stuntmangMUSIC 2 роки тому +2

      Agreed I just hope I live to see the progress he contributes to get this stuff legalized.

    • @blazingstar9638
      @blazingstar9638 2 роки тому +1

      @@melparadise7378 😂 true. I get the same feeling from Terrence McKenna

    • @benayers8622
      @benayers8622 Рік тому

      Strangely if it was about anyone else id think it was an insult but i get it, i get it lol..

    • @Pluralofvinylisvinyls
      @Pluralofvinylisvinyls 6 місяців тому

      I do the same. I always wake up to some random part where he’s talking about the synthesis of something I will never understand

  • @Shoutinthewind
    @Shoutinthewind 2 роки тому +12

    “When everybody feels comfortable hating something that is the time when you need to be most cautious because that’s when people really get into trouble….I call it unoriginal hatred and I think it is one of the most dangerous forces” Hamilton Morris
    Wisdom

  • @cloudbloom
    @cloudbloom 2 роки тому +13

    Starts at 3:50

  • @mosesinvests
    @mosesinvests 2 роки тому +6

    Such a pleasure to hear an intelligent exchange of ideas. Thank you both.

  • @zacharykonopa2718
    @zacharykonopa2718 2 роки тому +2

    Great casual interview and lovely answers from Hamilton as always. Definitely checking your other podcast episodes after this.

  • @jchastain789
    @jchastain789 2 роки тому +3

    This interview is a gem

  • @wendywoodruff3521
    @wendywoodruff3521 2 роки тому +2

    Thank you! This was great. I hadn’t yet heard him speak about the reasons and intentions he had for choosing which drugs to include for his show. He makes it easy to see how this is exciting., and why stigmas and biases need to change.

  • @76blackwidow
    @76blackwidow 2 роки тому +4

    Thank you, I adore Hamilton. Wish there were video

  • @joedavis4150
    @joedavis4150 2 роки тому

    ... Great conversation!... Thank you...... one prayer covers it all... Pray for the health of everything.

  • @belledejour280
    @belledejour280 2 роки тому

    loved the interview!!

  • @nataliezementbeisser1492
    @nataliezementbeisser1492 2 роки тому +60

    Hamilton is working on it to become the next Sasha Shulgin

    • @brucebrandy9433
      @brucebrandy9433 2 роки тому +12

      I have said this very thing, many times. I feel his passion for wanting the facts out there is epic, and he speaks in a calming, informative way that's easy to understand. He is a hero to me.

    • @HauntedHarmonics
      @HauntedHarmonics 2 роки тому +6

      Did you see his podcast with Dennis McKenna? He basically told Hamilton as much lol. He said “get to work Hamilton, this is your job now, the torch has been passed to you”
      I wonder how surreal that moment must have been for him, having Terrance’s brother tell him that is now his job to take on the work & legacy of legends like Mckenna and Shulgin

    • @judesch8927
      @judesch8927 2 роки тому

      @@HauntedHarmonics is this on the patreon on what?

    • @HauntedHarmonics
      @HauntedHarmonics 2 роки тому

      @@judesch8927 yep, patreon

    • @mattzetts6501
      @mattzetts6501 Рік тому

      ​@@judesch8927 the episode is now on Hamilton's main UA-cam channel and Spotify podcast list :)

  • @chriseps4256
    @chriseps4256 2 роки тому +1

    Anything with Hamilton Morris is always fucking EXCELLENT. I’d pay any such ridiculous amount of money to sit down with him for an hour of his time.

  • @syguzman5739
    @syguzman5739 2 роки тому +2

    I ❤ NHM
    Thank you for this interview!

  • @BlAcKpHrAcK
    @BlAcKpHrAcK 8 місяців тому +1

    I remember swimming on PCP with friends, many noted that we felt dry while in the water ..it was the thing we did most often on PCP.

  • @illjester_4203
    @illjester_4203 2 роки тому +2

    Time stamps needed please! Much love!

    • @kafka27
      @kafka27 2 роки тому

      the WHOLE video time stamp : NOW

  • @jPup_
    @jPup_ 2 роки тому +18

    “A good Christian boy who’s got it all going for him. He plays baseball. He loves The Lord.”

    • @johnthicks8568
      @johnthicks8568 2 роки тому +4

      Maybe he can do LSD and throw a no hitter in the pros like Dock Phillip Ellis Jr. 😄🤙😂

    • @unbalancedlibra9788
      @unbalancedlibra9788 Рік тому +1

      @@AtortAerials not true. Not all straight edge religious people are miserable hypocrites. A lot are though

    • @AtortAerials
      @AtortAerials Рік тому

      @@unbalancedlibra9788 I forgot what the comment was all about…I’m sure I was just goofing anyway.

  • @naftalibendavid
    @naftalibendavid 2 роки тому +2

    Splendid work.

  • @Perenbarn
    @Perenbarn 2 роки тому

    first question already the most asked question he ever got

  • @Shaktipat6
    @Shaktipat6 2 роки тому +4

    Hamilton you deserve one million mushrooms.

  • @BLUEGENE13
    @BLUEGENE13 11 місяців тому

    The idea that the pressure and strength to prohibit and criminalize drugs out weighs just either not doing that or helping the addicted and poor amazes me

  • @truthtoad
    @truthtoad Рік тому

    I just found your podcast! Wish I could join you in New York! I have some reports from the fringe! NDE and a fall to ...well, we should talk. I am starting a new conservation project I'll contact you about, you'll be glad I TOAD you. Thanks for your work!

  • @pvtbadtouch6540
    @pvtbadtouch6540 2 роки тому +5

    anecdotally, in regards to the ant -inflammatory effects i find 2cb to be very effective for muscle pain as well as making stretching and exercise more effective.

    • @marcusfoust5050
      @marcusfoust5050 2 роки тому

      I could say the same thing in regards to Dxm; any correlation?

    • @pricklycats
      @pricklycats Рік тому

      ​@@marcusfoust5050 They use ketamine for pain so it's the same as that. But it's not actually making your muscles more flexible, it's just making you not able to feel pain. So you could be injuring yourself and not notice until after.

    • @pricklycats
      @pricklycats Рік тому

      I've never tried 2cb but I've tried most of the others and shrooms specifically actually give me pain, probably because of the vasoconstriction, but I don't get that from LSD or other psychedelics. I just assumed 2cb would cause vasoconstriction as well, which should have the opposite effect of what you're saying, but I guess not.

    • @pricklycats
      @pricklycats Рік тому +1

      I have pain already, but whenever I take mushrooms now, it always makes my pain way worse. For multiple days. I can't use it anymore for that reason, though it didn't used to do that even though I've always had pain. Never heard of anyone else having it, probably because people are too afraid to admit shrooms could have a negative effect in any way.

  • @joedavis4150
    @joedavis4150 2 роки тому +1

    ... Here is something important people should know... the plain of jars in the Golden Triangle is most likely an ancient work of art honoring the Opium poppy. The jars are shaped like poppy pods, and are scattered randomly, like poppies in a field. Evidence for burials is scant.... look up pictures of the plain of jars, and of hill-tribe opium Harvest, and of Hill tribe culture. Hill tribe women have beautiful headdresses featuring imitation poppy pods framing their faces.... thankfully, the plain of jars is now a world heritage site.

  • @AtortAerials
    @AtortAerials 2 роки тому

    I really wish we could have seen you guys talking only bummer.

  • @triple_gem_shining
    @triple_gem_shining Рік тому +1

    Have Hamilton back on... It's your most popular episode

  • @RamonOzuna-sb4du
    @RamonOzuna-sb4du 10 місяців тому +1

    Am broke as fuck due to mental health and psychedelics change my whole mindset

  • @stevengill1736
    @stevengill1736 11 місяців тому

    It's amazing to me that 5-MeODMT went under the radar for so long - a friend picked up a gram in '78 and we smoked a little...it was quite impressive, but for some reason it never really caught on, but lt continued to be available for more than 20 years. It might have continued to be available a little longer, but it's appearance online
    along with some other little known compounds like 2-CT-7 spelled it's doom.
    So great that you and Jason are carrying the torch forward...cheers!

    • @WarlordEnthusiast
      @WarlordEnthusiast 7 місяців тому

      Probably because its alot more dangerous than N'N DMT in terms of dosage and a bit more intense than it. Regular DMT is alot more forgiving and readily available.
      A shame about 2-CT-7, the 2C-X series is just awesome and the more obscure ones are much more difficult to find even on the DNMs.

  • @mindhunter00789
    @mindhunter00789 2 роки тому +3

    PCP@ the right dose is incredible

  • @trulyliving9062
    @trulyliving9062 2 роки тому +2

    Personally I like Mr. Wiley and his thoughts and viewpoints on dolphins kind he expressed how he thinks while he’s on the substance and it was very different from 5he people eating reports

  • @renanrenan2642
    @renanrenan2642 2 роки тому +2

    i see hamilton i click

  • @Community_Guideline_Violator
    @Community_Guideline_Violator Місяць тому +1

    Ahhhh yes, “lush” Pennsylvania.

  • @brianallen8588
    @brianallen8588 2 роки тому +1

    My brother in lore Dr Ivan Casselman did his doctorate here in Lismore at Southern Cross Uni on Salvia. He loved the UA-cam clips because he could study it without influencing the experiment. He said only 15% of the Salvia UA-cam experiences were considered negative by the users. The media just focused on the negative ones ☮️

    • @waltersobchak7275
      @waltersobchak7275 2 роки тому +1

      Shit is absolutely horrible I did every kind of substance known to man except for smoke crack and shoot heroin and fentanyl and I’ll tell you what… It’s no no no no no. I’ve ate 10 strips 100 mg for ACO DMT whatever MXE PCP PCE I mean any exotic thing you can think of Salvia no way in hell no

    • @brianallen8588
      @brianallen8588 2 роки тому +1

      @@waltersobchak7275 indeed it is uniquely different

    • @waltersobchak7275
      @waltersobchak7275 2 роки тому

      @@brianallen8588 it’s like being trapped underneath the carpet like the carpet rolled up and rolled over me and trapped me underneath the carpet and it kept rolling like a wave over me and I was just tumbling tumbling tumbling tumbling it’s like I was suffocating and I couldn’t get out of it was like a loop. A thought loop. Now this didn’t happen once it happened like four times I was dumb enough to do it four times. Yes after that I wrote it completely off.
      The same with the methylated tryptamine after about 75 or 80 experiences and no machine elves all I’m getting here is Hindu-based situations. I don’t subscribe to that so sayonara on that too. I mean it wasn’t bad experience but it was like is this is it? This is what McKenna and them we’re raving about for so many years this is what Rogan raved about? Yeah no sorry. Also each time was like actually going to the physical process of dying it really was in order to get to the breakthrough it was like physically dying.
      I mean not painful but rather freaking intense you know. When you blow that last breath out it’s like you keep breathing out but you’re really not and it’s like you’re stuck in a food dehydrator and you’re being sucked dry until it’s almost painful and every thought is racing through your head and then you kind of like implode into something. A membrane maybe, then there they are waiting for me the Hindu deities. Oh no no no. Why would a Southern Baptist be seeing that? Yes they say you hallucinate what your experiences have been in life. I never seen any of that I had to look it up then I spotted it in a book OK that’s what I’m seeing, what is this you know?
      Did I see it in the movie and forget I don’t know I’m old. There was always like a female presence I can’t lie about that it was a female or motherly situation. It always seemed like it was not happy with me. Not really mad but you can feel like, when you’re a kid you do something wrong in front of your mother and you know you done wrong that’s the feeling I had every time.
      Now you wanna try something that is better than all of this more therapeutic and you can remember it? Yeah absolutely most rewarding substance I’ve ever encountered in my life and this is coming from a diehard stimulate head who loves exotic stimulants immensely. it’s called methoxetamine. It is pure magic it is bliss it is the holy grail of all substances illicit or otherwise.
      I’m actually more literate than I appear in this post but I’m using speech to text cause my hand is cut sorry it’s hard to read. So maybe you can help me out tell me what my problem is what’s up with you with the Hindu deities? As for the Salvia is not an option anymore it doesn’t exist to me😳😳🤣🤣🤣

    • @waltersobchak7275
      @waltersobchak7275 2 роки тому

      @@brianallen8588 let me know if you see this man so I can delete it

    • @SkateIslam
      @SkateIslam 2 роки тому

      @@waltersobchak7275 interesting experience you’ve had there. Never done salvia myself or much else to speak from experience. I’ve heard that smoking salvia is the worst way to take it. It’s spirit doesn’t like fire. The traditional way is to eat the leaves and it seems much less intense that way. Could be dosage and administration related. But don’t do it if you don’t want to.

  • @michaelfieldssportsbettor9590
    @michaelfieldssportsbettor9590 Рік тому +1

    It was available in Louisville until the mid 1990s..a chemical supply company had it in stock ..no Id required..

    • @pricklycats
      @pricklycats Рік тому

      There's still hundreds of psychedelics you can get online. Also in Canada you can even order illegal drugs on the clearnet as well, not just legal ones. I can just order some MDMA right now if I wanted to and have it in my mail box in 4 days. It's pretty crazy.

  • @martaavlas7970
    @martaavlas7970 2 роки тому

    “Identifying natural products based exclusively on mass spec or GCMS is not ideal, you have to do a lot of work to definitively characterize the structures” (29:39) Does anybody know what would be ideal? HPLC?

    • @Hippiekinkster
      @Hippiekinkster 2 роки тому

      You need a combination of techniques... after the acid-base extraction and recrystalization, do a melting point. If it's sharp and matches the literature, clean it up with chromatography. Verify w/ GCMS (there are libraries for the spectra of nearly everything). A polarimeter will tell you if it's -R, -S, or racemic... there are ways to isolate enantiomers. After that, MRI and X-ray crystallography, both of which are expensive, time-consuming, and require great skill. Just my guess.

  • @niklashultkrantz7766
    @niklashultkrantz7766 2 роки тому +1

    Starts at 4.30

  • @Maquis1943
    @Maquis1943 2 роки тому +4

    I'm confused. No one is saying the critiques of Compass have anything to do with not wanting Hamilton or Jason to have the ability to do this work. The real question is why is Compass funding it? As a for-profit company that has patented a psilocybin manufacturing process (and, to be clear, as part of allowing "their" compound to be used in research apparently gets the right to refuse the publication of data-meaning data that might possibly put their "investment" in a negative light-) what's in it for Compass to fund Hamilton's research? Why is Hamilton not addressing this important question openly and articulately?
    As a participant in a MAPS-funded clinical trial, I'm *especially* sensitive to the ethical responsibility researchers have to their participants (MAPS does it right, BTW). Compass seems absolutely opaque and untrustworthy in this respect, and I have genuine concern for the well-being of the participants in Compass trials. Hamilton's science- and data-driven perspective on drugs is vital to our society-why would he not see Compass' ability to possibly *manipulate* data for its own ends as a serious red flag?
    And for the record, I don't believe people championing the ethical responsibility of a profit-driven corporation to produce good data-especially when they are using the fragile mental health outcomes of human beings as that data-as being "fringe moralists". While research and chemistry are clearly fundamental, the history of questionable-and even destructive ethics within those industries must be acknowledged and safeguarded against. Ultimately it is the human beings at the other end of the equation that often get the rawest deals. Hamilton, I know you can do better...

    • @benayers8622
      @benayers8622 Рік тому

      Because hes still human, he will put himself first. Remember he is fully materialist, hes not like a saint or shaman who would put the world before themselves

  • @brettgreen853
    @brettgreen853 3 місяці тому +2

    5-meo-DMT is the Cadillac of the Triptymine. Its little cousin N,N Dimethyltryptamine is the Porche model. Both extremely classy, and a step above your average LSD, unless you are ingesting Sandoz, Owsley, or Nicki Sands finished product. Everything else is mid-tier, although i have never had anything by pickard, shulgin, or one or two others in that circle. We have been blessed to have been able to test and take the sacrament ourselves and with people we care sbout to traverse the unknown.

  • @asemic
    @asemic 2 роки тому

    i wanna hear more about the sand dollar walkie-talkies

  • @dire12343
    @dire12343 11 місяців тому

    PCP is my favorite of all drugs....i smoked it 10 years straight bottle after bottle...

  • @andredeyoung
    @andredeyoung 7 місяців тому

    Hamiltoooon❤

  • @gaetanozorzi2055
    @gaetanozorzi2055 Рік тому

    I remember Dr. Drew saying that psilocybin mushrooms caused their effects because of food poisoning, lol...

  • @aaronstone628
    @aaronstone628 2 роки тому +1

    What’s that cream shirt he was talking about?

    • @PsychedelicsToday
      @PsychedelicsToday  Рік тому

      Looks like it's sold out, but it was here: shop.creamforever.com/collections/shirts

    • @mattzetts6501
      @mattzetts6501 Рік тому

      ​@@PsychedelicsToday some of the coolest designed t shirts. thanks for posting this link. will definitely be ordering something from them! Amazing podcast btw.

  • @jussiniemi9560
    @jussiniemi9560 11 місяців тому

    So there actually is a Universe Of Science :O

  • @dire12343
    @dire12343 11 місяців тому

    Pcp really changed me for the better.. eating excersize morally better...

  • @chadkline4268
    @chadkline4268 2 роки тому +4

    Hamilton should start an online psychedelic chemistry class. If he charged $300/student, I am sure he could make millions. Not everyone lives near a university, but many have basic foundations in chemistry, they just lack practice in the various trchniques. The final exam has to include the ability to make whatever you like.

    • @mack2001x
      @mack2001x 2 роки тому

      you cant sell a class on how to make drugs 😂

    • @chadkline4268
      @chadkline4268 2 роки тому

      @@mack2001x they sell books, I think free speech rules. He might have to stop at the last step.

    • @natalyawoop4263
      @natalyawoop4263 2 роки тому

      Cool idea, but it takes many years of full time work to get to the point where you can just make any chemical you feel like.

    • @chadkline4268
      @chadkline4268 2 роки тому +1

      @@natalyawoop4263 my idea was like this:
      1. Here is what we make today ... Various precursors ... Here is the chemical reaction that takes place ... 1M of this, 2.5 moles of that, ...
      2. You will need these chemicals which can be purchased here ... At a good price ... Maybe this could be used to ensure the enrollment fee; ie, making the chems easily available at a central location.
      3. Perform the reaction with notes on things to be careful of, demonstrating the yield.
      Try to avoid amalgam reductions. I hate seeing them promulgated since Mercury is so toxic. Try to use electrochemical reductions and methods that do not create toxic waste.

    • @natalyawoop4263
      @natalyawoop4263 2 роки тому +1

      @@chadkline4268 okay yeah that sounds good, a lot like you might get in a university organic chem class

  • @user-uu2dq3ib5z
    @user-uu2dq3ib5z 2 роки тому

    but then you badmouth Carl Hart???..in other interviews

  • @painmt651
    @painmt651 2 роки тому +5

    I find mushrooms to be more than adequate for mental exploration, and therapeutic use. Depending on dose, you can have a mild, or mind shattering experience. People who have LIMITED EXPERIENCE talk about shrooms as being inferior to DMT....lol... they are just wrong!

    • @devilsolution9781
      @devilsolution9781 2 роки тому +1

      It is 4-ho-dmt ....

    • @georgebethos7890
      @georgebethos7890 2 роки тому

      @@mrs_Mccoy good for you

    • @pricklycats
      @pricklycats Рік тому

      They're all the basically the same, it's about the dose. I prefer LSD because it lasts long enough to actually have time to integrate something into real life. With DMT or shrooms, I have a lot of profound insights while I'm on the drug, but it's over as fast as it begins. Shrooms are way more confusing than most other psychedelics I've tried. Plus the stimulation of LSD helps to promote actually doing something and not just laying there melting into your bed.
      Also shrooms make my back pain worse now for some reason, so I basically cannot use them. Like literally every time I take shrooms now I get horrible back pain. But I don't get that from any other psychedelic, so I have a feeling it's something to do with the actual mushroom material and not just the vasoconstriction or whatever, since LSD also causes vasoconstriction but does not give me back pain.

    • @benayers8622
      @benayers8622 Рік тому

      @@pricklycats i understand bro.. Us people of true wisdom are very rare imo, especially online i myself only use youtube no other social media or online stuff and i only use youtube because Uk TV adverts are propaganda loaded negative placebos designed to rape your brain

  • @localxlocos
    @localxlocos 2 роки тому

    Hamilton sounds like a toad, ribbit

  • @BLUEGENE13
    @BLUEGENE13 11 місяців тому

    Drugs can be addictive and addiction is a real medical problem
    Drug addicts should just quit
    Pick one
    Edit:note picking the former it follows that you can take as much heroin and cocaine as you want

  • @michaelfieldssportsbettor9590
    @michaelfieldssportsbettor9590 Рік тому +1

    Kids don't try any of this stuff..it's not for everyone..

    • @pricklycats
      @pricklycats Рік тому +1

      Too late already tried everything 😅

  • @mrconor6842
    @mrconor6842 2 роки тому +2

    Shut up rambling and start the podcast

  • @tcorourke2007
    @tcorourke2007 2 роки тому +4

    Starts at 3:50