An Overview of Interleukin-12/Interferon-Gamma Axis

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. The pathogen enters the body by crossing the mechanical barriers. It is arrested and phagocytosed by the phagocytes.
After phagocytosis and antigen presentation, the macrophages release interleukin-12.
Interleukin-12 travels via blood to lymph nodes and convert naive T cell to helper T cell 1.
In this video, Dr. Mobeen Syed explains that interleukin-12 from the macrophages causes the conversion of naive helper T cell to helper T cell 1.
Helper T cell 1 starts secreting interleukin-2 and interferon-gamma.
In this video, Dr. Mobeen Syed describes that macrophage activates the acquired-arm of the immune system. The acquired immune system returns the favor and sends signals back to macrophages.
Helper T cell 1 releases interferon-gamma, which increases the activities of macrophages. Thus, forming interleukin-12/interferon-gamma axis.
In this way, the acquired arm acts as an enhancer of the innate arm of the immune system.
Interferon-gamma is significant for the macrophages to capture more and more pathogens and kill them.
Visit www.Drbeen.com for complete information about the processes occurring in the immune system.
The following topics have discussed in the video:
* Macrophage as a bridge between innate and acquired immunity
* Role of interleukin-12 in enhancing the acquired-immunity
* Role of interferon-gamma in enhancing innate-immunity
* Significance of interleukin-12/interferon-gamma axis ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.

[@datpham1439]

These short segment videos are perfect for USMLE Step 2.

[@Come-and-take-it]

thank you so much for helping med students passing their exams :))

[@gia607]

Great explanation, Thank you so much!

[@DrBeenMedicalLectures]

You are very welcome

[@Kayleigh-kx6hb]

very good explanation. Thank you so much!

[@halfmindlive]

Very nice

[@DrBeenMedicalLectures]

Thank you

[@juyalashish4]

You say gama interferon and writing alpha interferon

[@DrBeenMedicalLectures]

I sometimes make such mistakes 😭

[@juyalashish4]

@@DrBeenMedicalLectures lecture is amazing

[@dubhaltaghohearcain2431]

Is gamma inteferon an available supplement

[@kdcruz75]

Thanks for the explanation...
Do u have lectures on how the interpheron gamma also activates aerobic glycolysis..
Google : interpheron gamma aerobic glycolysis

[@DrBeenMedicalLectures]

Not yet