Відео

Hi Professor! Thanks for such an informative video. I was searching everywhere for some information regarding Pregabalin dosage for cats with FHS. We transitioned from Gabapentin at 100mg twice daily several months ago as my cat started refusing to take the meds in her food. We commenced Pregabalin at 25mg twice daily and in fact, her symptoms seemed improved. That was until the last week or so when she started tail biting/attacking again. I called my vet today who said to increase her dose to a total of 75mg daily (either 25mg x 3 or 3 capsules split into two doses). I’m concerned that this is too high a dose? She weighs around 6.3kg (gained weight since starting Pregabalin 🫣) I did give her a second 25mg dose today around 8hrs after the first with a plan to give her a third one before bed, however the second one really made her quite sedated/sleepy? Is this normal? She was never this quiet with the 2 x 25mg daily given roughly 12hrs apart. Thanks so much for your invaluable advice 😻

Hi we have a 9 year old Chihuahua that was diagnosed by MRI having Chiari malformation. The doctor has advised against surgery and our dog is now on medication since 5 weeks. The medication is 1x 5 mg dermipred, 1x 5mg Losec-mups, and 2x 25mg Lyrica a day. In the beginning of the treatment we saw a big improvement in his condition when dermipred 5 mg was given. His condition was the he lost like 70% of his strength from one minute to the other and could barely stand on his feet, Falling regularly on his face while walking. Since dermipred i would say his strenght is now at 50% but he is not getting stronger. We also tried 3x gabapentine instead of the 2x 25mg Lyrica when we started the treatment but it seems that while his condition improves, it does not seem to be enough to get him trough a full day without pain. I am reaching out to everyone who has expertise on this terrible disease to get as much information on how to improve his life. All information is very welcome thank you.

My dog has been diagnosed with CM/SM, and every time after she eats, she runs to my bed and energetically rubs her head, then burrows under the blankets or pillows. In the end, she sticks her head back out.Before the diagnosis, I always thought she was just having zoomies because she enjoyed her food. Now I constantly wonder if she's in pain after eating since she only does this after meals. How can I tell if eating is causing her pain? Is that possible, and if so, why?

Thanks for the video and the book recommendation! Great read!

Thank you, Claire -- very nice summary. I will add that over the last 14 years we have not had a repeat surgery. I do exactly what you illustrated here (FMD, duroplasty, and SIS). I suture the SIS over the duroplasty defect and then place an autologous fat graft over the site. Like you, we don't have all the follow-up we would like, but in a coupe of cases, the repeat MRI at 3 years has shown the fat graft in place. Significant reduction in the syrinx, as you have said, is uncommon, but improvement is not uncommon -- at least on all of our follow-ups, we have always seen improvement -- usually with medications, sometimes not. I will say that we have seen a reduction in the syrinx in patients we perform this at less than 2 years of age. Many thanks! Andy

Thank you so much for this information. My 6 year old Cavalier 11 kilos developed SM about a year ago, we don’t have MRI available in Tasmania and it would be very expensive and not worth doing unless you were having the surgery done. Willow has been on Gaberpentin 100 mg and ended up having 5 or so capsules a day for about 10 months. Another vet recently changed her to Pregabalin 25 mg capsules 2 twelve hours apart, as she had some breakthroughs we give 2 at night and 3 spread out through the day but Im wondering if they are better given two together maybe 3 time in 24 hours. She dosen’t yelp in pain but does head rubbing body twisting and some scratching. Still likes her walks etc and quite bright but yes has put on a lot of weight, doesn’t have heart trouble at the moment. Unfortunately my vet has not had a lot odd cases of SM so prefers if I do my own research. Thank you Liz.

I want to thank you so much for this beautiful presentation... I am so grateful that one of you genius' has found a way to spell this out in laymen's terms..... I am currently fighting off any signs of suffering in my 13 year old Cav with gabapentine prednisone, prilosec, and CBD. As well as treating her heart murmur with cardiac meds.... I refuse to allow her or any of my sweet pups suffer but the comfort measures can only take us so far before we need to make a hard decision...

Such a helpful and interesting video! Do you think that dogs with idiopathic epilepsy who used to have seizures no more frequently than once a month and who have now put on excessive weight due to Phenobarbital should be switched to Imepitoin? A lot of vets who put epileptic dogs on Phenobarbital don't ever bother monitoring their blood or checking their livers, so maybe it would be a safer option too in that case?

Very useful video！ The NSAID drug you mentioned in the video, is called "grappa print"? can you tell me the right name plz？

Hello doctor, thank you very much for this video. My dog, a 10 year 7 month old golden retriever, was treated with radiation therapy treatment (for brain meningioma) 4 months ago, and she has been on a mild dose of pregabalin 100 mg 2x 1 tablet daily (3 mg /kg twice daily) for the last 4 months. Recently, we observed a strange head twitching for half an hour; during this time, she was completely active and responsive. Could you please advise if it could be a side effect of pregabalin that showed as a myoclonus-type seizure? If Pregabalin is tapered down and eventually stopped, will it help her? The other anti-epileptic drug my dog takes is Levetiracetam 500 mg 3x 2 tablets daily. Please suggest. Thank you very much.

Very good. Thanks ❤

Thank you for an excellent presentation. I have a question. Are UC-II collagen supplements contradicted when a dog is on long term Pregabalin treatment? The literature does not seem to address that question. Thank you

Thank you, it was important for me to hear that cats liver does not filter as readily as dog livers. I will be mindful of that.

My little Maltese just went for an MRI for a slipped disc & they discovered he has this 😢 hopefully picking him up later today.

What an interesting case ! Thank you !

Very clear explanation thank you, helps me better how to manage as a person with a dog that has a spinal injury

Brilliant thank you

This was a fascinating video, thank you!

Hello :), I just wanted to say thank you so much for these videos! I am currently studying for my Board exams in Veterinary Behaviour Medicine (American & European Colleges) and have loved watching and listening to your videos for some of the psychopharmacology and the neurology that I need to know !! Thanks again !!

Fantastic delivery Prof. Had a couple of cases managed with Polypharmacy and Swimming hydrotherapy with excellent recovery process. I'm glad you clearly stated cage/crate rest should be well defined to Pet owners. With this i'm more confident to help Pets with IVDD and i hope to learn more from great tutors Like you in future. Thanks Once again Prof.

Fantastic delivery Prof. Had a couple of cases managed with Polypharmacy and Swimming hydrotherapy with excellent recovery process. I'm glad you clearly stated cage/crate rest should be well defined to Pet owners. With this i'm more confident to help Pets with IVDD and i hope to learn more from great tutors Like you in future. Thanks Once again Prof.

Thank you for the great explanation

Thank you for the informative video! My doxie was recently diagnosed with lvl 2 IVDD. Took MRIs and decided to go the conservative route since her pain was manageable with medication and the hernia was relatively small. I’m already seeing a huge improvement in her walking after 5 days. Will be starting physiotherapy and hydrotherapy tomorrow 😊 Biggest difficulty this far has been keeping her resting, as she’s full of energy now that we’ve found effective pain management!

I used to be scared of neurology because I found my teacher in uni to be very confusing, but watching your videos and also your presentations at the ISFM Congress have made me feel more confident! Thank you very much!

Very good. Thanks 🎉

Thanks for sharing this case .

Good video!

What is the suitable time to perform an MRI scan in an epileptic dog after it has a seizure event to prevent postictal edema sign in MRI?

I have had all over pain for years. I now am looking for chores to do because movement is not painful and I am not drugged up! Almost 20 years of playing solitaire, my life has changed!

I just found this channel. Thank you so much for your content! I have an 8-year-old 4 lb Yorkie with chiari like malformation and syringomyelia. I've always wondered if it's okay for him to fly in an airplane with me??. He was diagnosed at 3 years old. And has been on omeprazole and gabapentin regularly

Thank you so much for this! I am revising for my exams and this is great. Thank you for including so many cat videos (vet med is rather dog-dominated!).

Thanks for this. 8 years ago I had a cavalier with chiari malformation and SM, and gabapentin seemed to keep her mostly comfortable for a few years and then she got more painful episodes so I changed to pregabalin. The painful episodes seemed less frequent but were still intense. They occurred out of the blue but were worse with excitement or if she was in the hot sun. One bad one occurred after someone left salty crisps lying about which she ate. I am convinced this induced a very painful episode for her. At these times she would scratch intensely at the back of her head and then collapse on the floor scratching and then he body seemed to go into a spasm as if in pain, but she was still aware and awake. They tended to last a minute or so and then she got up as if she was tired. I tried many other drugs for her as well over the years but the pregabalin seemed most effective.

Thank you for this video, Professor.

Thank you so much for your video. This is invaluable help!!!

Hello, i just found yourbpage today, April 29, 2024. Is there anyway you could contact me?? I am in dire straights. I need advice and help. I took my Cavalier to a Neurologist and she put him on Prednisone along with other drugs. He has been on them for a while now at least 2 yrs. He just turned 6yrs and i am so upset because I dont want him on this Steriod anymore, and I am being told that is all that will help him. PLEASE HELP ME... Thank you

My dog was just prescribed pregablin for seizures or possible dyskinesia. He was on generic keppra, but his anxiety has greatly increased since he started that drug. Do you think I should be concerned in using pregablin as an alternative treatment for his seizures?

Thank you for the lecture! It was so helpful !

Thank you ❤❤

Great video! Thank you Prof!... Sorry, but I thought the whippet/Italian grey hound has a hypermetric left fore?

Dear Professor Rusbridge, thank you so much for this video, it was very informative. I have two questions, please (unrelated to Pregabalin, though). What is your opinion on frunevetmab and bedinvetmab, please? I have been working with pets, and unfortunately it has been observed that many (some overall healthy, others with osteoarthritis) pets’ health deteriorated either shortly after the injection, or after few months of treatment. Some go blind, others get paralyzed or develop tonic/clonic seizures, ulcers, kidney issues, to name a few; or die. It has also been noticed that many vets in UK are prescribing those drugs either without a proper OA diagnosis, basing on presumptions/as a “just in case” solution; or for other health issues (for example, constipation, kidney issues…, toothache etc.). I believe many people, myself included, would greatly appreciate if you could please share your opinion on those medications. Second question relates to pet strokes and idiopathic epilepsy. Feline patient, age 13, healthy, suddenly developed occasional tonic seizures (only), diagnosed with idiopathic epilepsy and treated with Levetiracetam. Due to misdiagnosed stroke mistaken for an epileptic attack few months later, patient was prescribed Phenobarbital on top of Levetiracetam. Developed excessive scratching of ears and face, which continues months after, despite stopping Phenobarbital after 10 days. No underlying cause can be found (vet & neurologist). Would that be a likely result of the stroke? I would appreciate if you could please discuss feline stroke in one of the videos as well. Thank you in advance. Respectfully, J. Mikaelson, LLB, Pet Rescuer LFPCSA (Lost & Found Pets in Cambridge and Surrounding Areas)

The book that I mention in this video is "The IVDD Handbook: Helping your dog through back and neck problems" Paperback ASIN ‏ : ‎ B0BFTWP9H5 ISBN-13 ‏ : ‎ 979-8351305097 it is really helpful in explaining how you build-up physiotherapy and also appropriate crates sizes etc (NB book is nothing to do with me and I don't gain anything from promoting it- I just think it is a great resource for vets, nurses and care-givers)

Thank you Professor, great informative video. I wonder if i could clarify regarding physiotherapy for those not going for surgery.. when will we institute it? After 4 wks of so of cage rest or whenever signs have improved and stable? Thank you.

This is a brilliant film! Thank you for such a clear explanation.

Simply the best

Thanks

Thank you very much for the lectures and books about Syringomyelia! Prof. Rusbridge, could you please tell me, is it possible to get your online consultation? Is there an online appointment? We live in another country, my Cavalier King Charles Spaniel has Chiari and Syringomyelia (According to MRI, extension of the central channel in the area C1-Th1, up to a maximum of 7.7x6.5 mm). The dog is 11 months old; a veterinary neurologist recommends not to take gabapentin, but to do surgery (foramen magnum decompression). We have some doubts. There is an MRI disk and a video of symptoms (phantom scratching), if a consultation is possible, please let me know. Thanks a lot!

What is the success rate of cagerest?

My girl was diagnosed with Chiara but not SM at least yet. She also has allergies so it's been hard to figure out what's what. The Neuro implied she shouldn't have pain if she doesn't have SM but I strongly suspect at least some of her issues are Neuro pain.

As a biologist and dog owner I appreciate your science based content. Hope you keep going and get plenty of subscriptions!

Amazing content. Thank you so much.