The Promise of Lithium book on Amazon amzn.to/3HSCP5R Renue By Science 10% discount: tinyurl.com/3bj65wev For Subscriptions, use code SUBMHS DoNotAge 10% discount code MODERNHEALTHSPAN donotage.org/products/ NOVOS Core & NOVOS Boost $5 with code MODERNnow5 novoslabs.com/?ref=3957 ProHealth 10% discount code MODERN : prohealth.pxf.io/c/3176409/1541296/17976 InsideTracker 20% discount: insidetracker.sjv.io/DVmqkn with code HEALTHSPAN20 Bulletproof 15% discount code HEALTHSPAN15 tinyurl.com/24hrxt72 If you would like to support our channel, we’d love a coffee ☕…thank you! www.buymeacoffee.com/mhealthspan Dr Guttuso Playlist: tinyurl.com/36ra6x2h
I'm diagnose with cancer, i have just 2 years to live, i've never been this scared to die, i'm just 35, i cry everyday wishing for a miracle to happen. i don't know why im saying this here. put me in your prayers.
im really sorry. i've was in such situation 15 months ago. i had just 2 months to live till a friend told me about a healer who helped me. She cured me, I don't know how she did it. but i owe her my life. she's the reason i'm alive today.
I’ve been taking Lithium micro dose 1000mcg daily for the past 6 months as part of my longevity supplement stack and I am now glad to see these podcasts covering the importance of Lithium for prevention against Dementia related diseases.
1000mcg is 1 mg which is nothing. Prof. Dale Bredesen uses Li in his protocol and mentions it in his reverse best selling Alzheimer's books. As I recall (not sure) the protocol is 40 mg of elemental Li/day so I take 5 mg qid to be conservative. Some well water contains Li in this range for a 4 liter per day intake. Still, do NOT take Li if you have kidney disease without a consult with a kidney specialist. I have ordered the book he mentioned. Another great interview so thanks to MHS.
I remember many years ago a man lectured a group of Parkinson's patients and asked all the smokers in the audience to raise their hands. No one did. He tied it to the high content of lithium in tobacco. I've been taking 5 mg. a day for over a decade and went from 3 clusters of 3 or 4 migraines a year to 4 episodes in over ten years. With all the studies that have been done, why has the FDA not established a minimum daily requirement? Lithium is cheap, has the pharmaceutical industry blocked the establishment of an MDR? Naturally occurring Lithium in drinking water has shown to be tied to lower rates of; murder, suicide, physical abuse, substance abuse as well as other neurological disorders. Big Pharma makes huge profits on mind altering anti-depressants with harsh side effects and other drugs. Iodine is added to our salt, the same could be done with Lithium Chloride, once used as a salt substitute. The old adage "An ounce of prevention is worth a pond of cure" rings true with Lithium.
Prevention is better yes. Anything used to treat should respect and protect (fully) informed consent with open free access to all studies with all reports of neg effects reported. Fluoride was added to public drinking water to ‘prevent dental carries’ and many studies now showing have more risk then benefit. The iodine in natural salt vs table salt/sodium chloride healthier and better recognized by human body. Search history of why iodine was added to sodium chloride.
As someone with a background in functional medicine, a few thoughts: 1. still amazed that someone would reference Neurology and Psychiatry as completely unrelated fields, but it's all the brain. If we were focused on the root causes of health problems (as opposed to indefinite pharmaceutical management), we would see NeuroPsych as more unified. 2. In the functional, integrative and naturopathic realm, lithium is viewed as an essential mineral for the brain so really not surprising it would help a variety of Neuropsych conditions. 3. particularly grateful that research trials are being done to clarify optimal doses, forms of lithium for underlying Neuropsych conditions. Lithium orotate supplementation in doses 5-40mg daily have been used by many for many years.
@@eightofhearts in high doses and for a long periods of time as given on prescripton to patients with bipolar disorder, may hurt the kidneys. But i'm talking about low doses (microdoses) of lithium carbonate.
Lithium is a GSK3 inhibitor, like one of the Yamanaka Factors. When combined with Inositol it helps with autophagy in the brain. Wonder why people are only talking about this now. We knew how good it was 10 years ago.
Thanks Richard. Have been taking low dose lithium (~ 1 to 2 mg daily) one and off for years. Also take selenium (~ 100 mcg/d) which deserves its own focus (ref. research by Vadim Gladyshev and others). Started an annual metals toxicity test to make sure Se etc are not off track.
Most interesting! I've been microdosing Li based on evidence I had encountered in the literature, and this info makes it all that much more intriguing. I'll be staying alert for your next installment on this (and hoping to hear any informed conjectures as to mechanism of action). Thank you!
i don't know the details, but my Dad took lithium for manic depression. he died in his early 60s with kidney failure which was attributed to the lithium.
Hi Steve, thanks for sharing, and sorry to hear that. Lithium for manic depression (bipolar disorder) is around 300 mg/day. The doses being investigated by Dr Guttuso are much lower. We talk about it in more detail later in the series.
Question. Would 5 mg of lithium orotate be effective? Please comment on the form and the dose. Thank you. My brother has parkinsons and leweys body dementia. Very important!
It should be noted that nicotine is associated with being Neuroprotective and can help explain the protective benefit of smoking. Lithium in water supply has been associated with reduced PD risk.
I want to know what the authors first hand experience is with patients. Are there others who are benefiting from the lithium with Parkinson’s disease or Alzheimer’s?
Hi George, thanks for your comment. I have not studied nicotine so no comment on whether it helps or not, however for lithium the smoking data is only one part of the available evidence.
Nope. It’s likely the lithium. Nicotine has negative cardiovascular risks at even small doses. It is a stimulant and may have a very temporary ability to enhance cognition, but in the long run it damages the cardiovascular system which itself increases the risk of dementia and cognitive decline.
@@m0ckingB1rd42 there are multiple studies that show efficacy of low dose nicotine taken intermittently improving memory and cognition, using nicotine replacement therapy, not smoking. Enjoy the read!
@@georgegeorge3294 Nicotine is a known nootropic substance, so this doesn't surprise me. I'm not aware of any evidence linking the use of isolated nicotine to reduced PD or AZ. The high concentration of lithium in tobacco leaves mentioned in this video could explain the PD connection.
What’s the difference between the supplement and the prescription? Didn’t you have another guess whose number 1 supplement was lithium? What daily dose?
Hi Scott, thanks for the question. The other guest who suggested lithium was Dr Kris Verburgh from NOVOS. I think their formulation includes 1 gram. We get into the daily dose later in the series. But in a nutshell, the prescription dose for bipolar disorder is typically 300mg lithium carbonate, supplements are available in 1 or 5mg capsules normally and are li orotate or aspartate. Which lithium salt is also probably not important, something else we discuss later.
@@ModernHealthspan Verburgh uses 1 mg (or 1,000 mcg), NOT 1 gram, in NOVOS Core. 300 mg/day is often used for treating bipolar disorder. Low-dose lithium is just 1-5 mg/day. Don't confuse mg & grams - a factor of 1,000 here is the difference between "likely to help" and "danger! watch out!" (Note that 1,000 mcg = 1 mg, and 1,000 mg = 1 g.)
Hi George, thanks for sharing. Interesting, in the book Dr Guttuso talks about a nicotine study that had a negative outcome, whereas this was positive. His conclusion was that it was not the nicotine.
I see many smokers and as a group they appear protected from early dementia, therefore a larger study or a large retrospective analysis should be performed
Hi Donny, thanks for the question. I cannot make any recommendations or find much evidence on this. There is this meta-analysis www.ahajournals.org/doi/10.1161/STROKEAHA.122.039203 which says that lithium helped in animal models but there was insufficient data in humans. The other thing to be aware of is this is probably given shortly after the stroke not at a later time point.
@@amandagreene-zc3bu Loong term side effects.. FROM what I read from A few Learned Doctors.. on You- Tube- But it depends on your Physician.. AND your Diagnosis/// this is from 5 months ago. So would need to do more research.. The NATURAL are extremely expensive.. And they not easy to get.. ! Can’t give your more Sorry!
Gaba is a better supplement for neurotransmitter and brain matter. Breathing and somatic release with exercise is a better way too. Acutely ask patients what they think.
Hi thanks for your comment. I believe that there is danger of kidney damage with long term use (many years) of lithium at prescription levels for bipolar (300 mg). The doses available in supplements are much lower (1-5mg). But dosing is an open question and one that is being investigated.
![АЛАУДИНОВ у Скабеевой: эти их ВСУ нас НЕ ДОГОНЯТ 😁 [Пародия]](http://i.ytimg.com/vi/an0anqU4WGQ/mqdefault.jpg)
The Promise of Lithium book on Amazon amzn.to/3HSCP5R
Renue By Science 10% discount: tinyurl.com/3bj65wev For Subscriptions, use code SUBMHS
DoNotAge 10% discount code MODERNHEALTHSPAN donotage.org/products/
NOVOS Core & NOVOS Boost $5 with code MODERNnow5 novoslabs.com/?ref=3957
ProHealth 10% discount code MODERN : prohealth.pxf.io/c/3176409/1541296/17976
InsideTracker 20% discount: insidetracker.sjv.io/DVmqkn with code HEALTHSPAN20
Bulletproof 15% discount code HEALTHSPAN15 tinyurl.com/24hrxt72
If you would like to support our channel, we’d love a coffee ☕…thank you! www.buymeacoffee.com/mhealthspan
Dr Guttuso Playlist: tinyurl.com/36ra6x2h
I'm diagnose with cancer, i have just 2 years to live, i've never been this scared to die, i'm just 35, i cry everyday wishing for a miracle to happen. i don't know why im saying this here. put me in your prayers.
im really sorry. i've was in such situation 15 months ago. i had just 2 months to live till a friend told me about a healer who helped me. She cured me, I don't know how she did it. but i owe her my life. she's the reason i'm alive today.
@@daviemanuel688 That's wonderful, how do i get in touch with the healer?
@@MajorCockbern Her name is Sylvia Regina White,and she is a great healer who can heal you.
@@daviemanuel688 Thank you very much. i just checked and i found her. i'm excited.
@@MajorCockbern I’m so sorry, what type of cancer? How can i contact you?
I’ve been taking Lithium micro dose 1000mcg daily for the past 6 months as part of my longevity supplement stack and I am now glad to see these podcasts covering the importance of Lithium for prevention against Dementia related diseases.
Yep, me too! Novoslabs includes it too.
Hi Bob, thanks for sharing. I am taking it too.
1000mcg is 1 mg which is nothing. Prof. Dale Bredesen uses Li in his protocol and mentions it in his reverse best selling Alzheimer's books. As I recall (not sure) the protocol is 40 mg of elemental Li/day so I take 5 mg qid to be conservative. Some well water contains Li in this range for a 4 liter per day intake. Still, do NOT take Li if you have kidney disease without a consult with a kidney specialist. I have ordered the book he mentioned. Another great interview so thanks to MHS.
I remember many years ago a man lectured a group of Parkinson's patients and asked all the smokers in the audience to raise their hands. No one did. He tied it to the high content of lithium in tobacco. I've been taking 5 mg. a day for over a decade and went from 3 clusters of 3 or 4 migraines a year to 4 episodes in over ten years. With all the studies that have been done, why has the FDA not established a minimum daily requirement? Lithium is cheap, has the pharmaceutical industry blocked the establishment of an MDR? Naturally occurring Lithium in drinking water has shown to be tied to lower rates of; murder, suicide, physical abuse, substance abuse as well as other neurological disorders. Big Pharma makes huge profits on mind altering anti-depressants with harsh side effects and other drugs. Iodine is added to our salt, the same could be done with Lithium Chloride, once used as a salt substitute. The old adage "An ounce of prevention is worth a pond of cure" rings true with Lithium.
Prevention is better yes. Anything used to treat should respect and protect (fully) informed consent with open free access to all studies with all reports of neg effects reported. Fluoride was added to public drinking water to ‘prevent dental carries’ and many studies now showing have more risk then benefit. The iodine in natural salt vs table salt/sodium chloride healthier and better recognized by human body. Search history of why iodine was added to sodium chloride.
Another great guest. Lithium seems very promising. I'm just started looking something for improving cognitive function. Thank you you both!
Hi Ray, thanks!
As someone with a background in functional medicine, a few thoughts: 1. still amazed that someone would reference Neurology and Psychiatry as completely unrelated fields, but it's all the brain. If we were focused on the root causes of health problems (as opposed to indefinite pharmaceutical management), we would see NeuroPsych as more unified. 2. In the functional, integrative and naturopathic realm, lithium is viewed as an essential mineral for the brain so really not surprising it would help a variety of Neuropsych conditions. 3. particularly grateful that research trials are being done to clarify optimal doses, forms of lithium for underlying Neuropsych conditions. Lithium orotate supplementation in doses 5-40mg daily have been used by many for many years.
Shouldn't it be lithium carbonate?
@@youssefgmail7 this is the one that hurts the kidneys
@@eightofhearts in high doses and for a long periods of time as given on prescripton to patients with bipolar disorder, may hurt the kidneys. But i'm talking about low doses (microdoses) of lithium carbonate.
Lithium is a GSK3 inhibitor, like one of the Yamanaka Factors.
When combined with Inositol it helps with autophagy in the brain.
Wonder why people are only talking about this now. We knew how good it was 10 years ago.
Thanks Richard. Have been taking low dose lithium (~ 1 to 2 mg daily) one and off for years. Also take selenium (~ 100 mcg/d) which deserves its own focus (ref. research by Vadim Gladyshev and others). Started an annual metals toxicity test to make sure Se etc are not off track.
Hi Peter, great thanks for sharing and the suggestion on selenium
This is very interesting, also Lithium supplement is very affordable👍
Hi Susan, thanks for sharing. Yes, it is quite reasonably priced.
High natural lithium levels in the water have been shown to be associated with lower suicide rates. Has anyone looked for a reduction in AD and PD?
Thanks, Richard. I'm now addicted to your interview series!
I started taking mini dose lithium 1mg-3mg a week ago for long covid, works well for me! Nice to see the author here, thank you!
Hi thanks for sharing. Long COVID is something we get to a bit later.
Ivermectin is what I was told by a doctor to take for Long Covid. Told to take it daily for a month.
Hi:-) how are you today, a year after? Did Lithium make a big difference for you concerning long covid? Thanks, all the best😊
Most interesting! I've been microdosing Li based on evidence I had encountered in the literature, and this info makes it all that much more intriguing. I'll be staying alert for your next installment on this (and hoping to hear any informed conjectures as to mechanism of action). Thank you!
Interesting video. Thank you.
Hi Olya, thanks!
i don't know the details, but my Dad took lithium for manic depression. he died in his early 60s with kidney failure which was attributed to the lithium.
The dose makes the poison.
Hi Steve, thanks for sharing, and sorry to hear that. Lithium for manic depression (bipolar disorder) is around 300 mg/day. The doses being investigated by Dr Guttuso are much lower. We talk about it in more detail later in the series.
I read somewhere that Kidney damage is mostly from taking Lithium carbonate not lithium orotate
My dad takes 500mg 2x a day for the same reason. However, he checks his kidneys every 6 months.
Question. Would 5 mg of lithium orotate be effective? Please comment on the form and the dose. Thank you. My brother has parkinsons and leweys body dementia. Very important!
Where is episode 2 please? I feel like this cut off before we got to the juicy part!
How do you think this area of investigation relates to the dietary intervention reported by Dr. Chris Palmer ("Brain Energy")?
Are there any new updates to report over on the Dr. Katcher front?
Hi MsScrubs, thanks for your comment. We will be releasing soon.
Yes, Richard had a video out on it a few days ago. All good news, Harald is really focused on trials with dogs and then humans.
Thanks Richard.
It should be noted that nicotine is associated with being Neuroprotective and can help explain the protective benefit of smoking. Lithium in water supply has been associated with reduced PD risk.
what is the over the counter lithium v prescription lithium? There is an obvious connection to be made here.
It would be good to know how much lithium is helpful and how much risks kidney problems.
Hi Gaby, thanks for your question. We talk about dosage in more detail in a later episode.
I want to know what the authors first hand experience is with patients. Are there others who are benefiting from the lithium with Parkinson’s disease or Alzheimer’s?
It’s not smoking but rather nicotine that is probably associated with a reduction of dementia
Hi George, thanks for your comment. I have not studied nicotine so no comment on whether it helps or not, however for lithium the smoking data is only one part of the available evidence.
Nope. It’s likely the lithium. Nicotine has negative cardiovascular risks at even small doses. It is a stimulant and may have a very temporary ability to enhance cognition, but in the long run it damages the cardiovascular system which itself increases the risk of dementia and cognitive decline.
@@m0ckingB1rd42 there are multiple studies that show efficacy of low dose nicotine taken intermittently improving memory and cognition, using nicotine replacement therapy, not smoking. Enjoy the read!
@@georgegeorge3294 Nicotine is a known nootropic substance, so this doesn't surprise me. I'm not aware of any evidence linking the use of isolated nicotine to reduced PD or AZ. The high concentration of lithium in tobacco leaves mentioned in this video could explain the PD connection.
What’s the difference between the supplement and the prescription? Didn’t you have another guess whose number 1 supplement was lithium? What daily dose?
Hi Scott, thanks for the question. The other guest who suggested lithium was Dr Kris Verburgh from NOVOS. I think their formulation includes 1 gram. We get into the daily dose later in the series. But in a nutshell, the prescription dose for bipolar disorder is typically 300mg lithium carbonate, supplements are available in 1 or 5mg capsules normally and are li orotate or aspartate. Which lithium salt is also probably not important, something else we discuss later.
@@ModernHealthspan Verburgh uses 1 mg (or 1,000 mcg), NOT 1 gram, in NOVOS Core. 300 mg/day is often used for treating bipolar disorder. Low-dose lithium is just 1-5 mg/day. Don't confuse mg & grams - a factor of 1,000 here is the difference between "likely to help" and "danger! watch out!"
(Note that 1,000 mcg = 1 mg, and 1,000 mg = 1 g.)
Nicotine treatment of mild cognitive impairment; P.Newhouse MD in the Journal “Neurology” 2012 Jan 10; 78(2): 91-101
Hi George, thanks for sharing. Interesting, in the book Dr Guttuso talks about a nicotine study that had a negative outcome, whereas this was positive. His conclusion was that it was not the nicotine.
I see many smokers and as a group they appear protected from early dementia, therefore a larger study or a large retrospective analysis should be performed
Do ear drops get to the brain cells?
I would not expect that, unless the compound had exceptionally high permeation, like DMSO.
Could Lithium help an 83 year old partially paralyzed stroke patient ?
Hi Donny, thanks for the question. I cannot make any recommendations or find much evidence on this. There is this meta-analysis www.ahajournals.org/doi/10.1161/STROKEAHA.122.039203 which says that lithium helped in animal models but there was insufficient data in humans. The other thing to be aware of is this is probably given shortly after the stroke not at a later time point.
@@ModernHealthspan thank you very very
IS there a natural Lithium? Available please?
Not Lithium Carbonate. !Not Lithium Orotate!
Thnx Kindly.🎉🎉
Why not Lithium Orotate!!!??
@@amandagreene-zc3bu Loong term side effects.. FROM what I read from A few Learned Doctors.. on You- Tube- But it depends on your Physician.. AND your Diagnosis/// this is from 5 months ago. So would need to do more research.. The NATURAL are extremely expensive.. And they not easy to get.. !
Can’t give your more Sorry!
Gaba is a better supplement for neurotransmitter and brain matter. Breathing and somatic release with exercise is a better way too. Acutely ask patients what they think.
L-tyrosine and Benfotiamine in the morning
Lithium orotate at night
That's all fine if you don't like your kidneys 😕
Hi thanks for your comment. I believe that there is danger of kidney damage with long term use (many years) of lithium at prescription levels for bipolar (300 mg). The doses available in supplements are much lower (1-5mg). But dosing is an open question and one that is being investigated.