The Promise of Lithium book amzn.to/3HSCP5R Renue By Science 10% discount: tinyurl.com/3bj65wev For Subscriptions, use code SUBMHS DoNotAge 10% discount code MODERNHEALTHSPAN donotage.org/products/ NOVOS Core & NOVOS Boost $5 with code MODERNnow5 novoslabs.com/?ref=3957 ProHealth 10% discount code MODERN : prohealth.pxf.io/c/3176409/1541296/17976 InsideTracker 20% discount: insidetracker.sjv.io/DVmqkn with code HEALTHSPAN20 Bulletproof 15% discount code HEALTHSPAN15 tinyurl.com/24hrxt72 If you would like to support our channel, we’d love a coffee ☕…thank you! www.buymeacoffee.com/mhealthspan Dr Guttuso Playlist: tinyurl.com/36ra6x2h
Lithium is a GSK3 inhibitor, like one of the Yamanaka Factors. Helps rejuvenate stem cells, particularly in skeletal muscle. It's one of the earliest ingredients I added to a muscle wastage reversal supplement I've been working on for 10 years, on and off. It alters the dynamics of how the body uses inositol, diacylglycerol, and phospholipids. Acts like a molecular switch to switch on another mode in the body and brain that I haven't fully mapped out what it does.
It also activates telomerase and they have shown longer telomere length associated with long term Lithium use. If not everyone is aware, long telomeres are associated with longevity.
@@brienq Technically, telomere loop dynamics is more important than length. You can lengthen telomeres without the proper loop dynamics, which can lead to cancer. Luckily, most chemicals that lengthen telomeres also ping the gene that restores loop dynamics, too. There are a couple that don't, though. Should be wary of them. Been a long while since I researched this, though. Forget which is which.
My young amazing wife is suffering so bad! 4 months aftwr shot, she crashed and never came back to normal. Severe anxiety, hair loss, sexual function ceasing all together, hormones all over, theyroid developed a nodule, and much more. But the chronic fatigue and debilitating anxiety is the worst. Were need answers! Now! This is evil!
Before I had long COVID in march 2020 every aging test showing was 15 years younger as I started supplements when I was 20 only and I looked that much younger too. Long COVID gave me grey hair within weeks!
i was taking a low dose of lithium orotate. between 5-10mg. it took me weeks, or months, to figure out it was responsible for the insomnia was dealing with. i couldn't get to sleep at all, wide awake most of the night. think what happened was in the beginning it wasn't having this effect, then this insomnia crept up on me and i didn't suspect the lithium which i thought would be helping sleep. i'm going back to taking it earlier in the day now
Thanks for sharing that, I just posted minutes ago how it gives me insomnia too which is very disappointing! Yes, I was wide awake too after taking 5 mg right before bed, but even if I take it in the morning I will still only get 5 or so hours sleep instead of my typical 7 hours.
@@brienq thanks for sharing as well. i took a few months off of it but just took it again yeserday morning and was able to sleep just fine. but how it may impact sleep as i continue to use it will be something to monitor. i will keep taking it in the morning and try and report back here about whether or not sleep eventually becomes effected or not
I’m not 100% certain of the benefits, but I’m feeling fine other than my freezing gait issues and diminishing voice. I will keep on taking 20 mg x2 daily.
Can you address concerns with lithium and kidney function? I believe there was a 2014 study saying that lithium degrade GFR but then there was a 2022 study saying lithium promotes kidney longevity. All very confusing.
It depends on the dose. Supplements generally are 10 MG or less, whereas prescription is probably 300 MG and should only be taken under medical supervision.
Hi Scott, thanks for the question, as Kitty has said it is to do with dose. Typical doses for bipolar disorder, for which it is prescribed are 300mg. Kidney issues are seen after many years at this dose. The dose here is 10 or 15 mg.
In medical science they usually speak of the elemental dosage when describing the bioactive effect of an elemental compound, so it would be 10 mg of elemental Li. It's also how they label the supplement's product name, i.e., Lithium Aspartate 10 mg is referring to the Li only.
No concern with sedation while sleeping? That sounds very ignorant about how important quality sleep is to brain function. Talk of sleep quality and onset of dementia is everywhere.
The Promise of Lithium book amzn.to/3HSCP5R
Renue By Science 10% discount: tinyurl.com/3bj65wev For Subscriptions, use code SUBMHS
DoNotAge 10% discount code MODERNHEALTHSPAN donotage.org/products/
NOVOS Core & NOVOS Boost $5 with code MODERNnow5 novoslabs.com/?ref=3957
ProHealth 10% discount code MODERN : prohealth.pxf.io/c/3176409/1541296/17976
InsideTracker 20% discount: insidetracker.sjv.io/DVmqkn with code HEALTHSPAN20
Bulletproof 15% discount code HEALTHSPAN15 tinyurl.com/24hrxt72
If you would like to support our channel, we’d love a coffee ☕…thank you! www.buymeacoffee.com/mhealthspan
Dr Guttuso Playlist: tinyurl.com/36ra6x2h
I just started several days ago and am amazed at the difference! Thanks for sharing this
You have long COVID and started lithium? It worked for you?
@@theancientsancients1769 Yes!!
Did you have PEM / Fatigue / POTs? If yes, did it help with it?
Very helpful! Wish the trial a success. Thank you Richard and Dr. Guttuso!🧡🧡
Hi Sparkling thanks and great to see you!
In Japan live span is long where Lithium is high in the dringking water.
Have you heard of “Crazy Water” found in Texas? It is high in Lithium.
Thanks for these interviews with Dr. Guttuso. Fascinating and I am going to give low dose Lithium a trial
Hi Thanks. Please let us know how the lithium goes.
Lithium is a GSK3 inhibitor, like one of the Yamanaka Factors. Helps rejuvenate stem cells, particularly in skeletal muscle.
It's one of the earliest ingredients I added to a muscle wastage reversal supplement I've been working on for 10 years, on and off.
It alters the dynamics of how the body uses inositol, diacylglycerol, and phospholipids.
Acts like a molecular switch to switch on another mode in the body and brain that I haven't fully mapped out what it does.
It also activates telomerase and they have shown longer telomere length associated with long term Lithium use. If not everyone is aware, long telomeres are associated with longevity.
@@brienq Technically, telomere loop dynamics is more important than length.
You can lengthen telomeres without the proper loop dynamics, which can lead to cancer.
Luckily, most chemicals that lengthen telomeres also ping the gene that restores loop dynamics, too.
There are a couple that don't, though. Should be wary of them.
Been a long while since I researched this, though. Forget which is which.
@@darkhorseman8263 Thank you for sharing this , it is new to me and I will need to read up on that.
hey do you use discord or tg? email maybe?
Precious episode, thank you!
My young amazing wife is suffering so bad! 4 months aftwr shot, she crashed and never came back to normal. Severe anxiety, hair loss, sexual function ceasing all together, hormones all over, theyroid developed a nodule, and much more.
But the chronic fatigue and debilitating anxiety is the worst.
Were need answers! Now! This is evil!
so sorry to hear this, it's awful.
Some people are getting relieved with nicotine patches
@@rebeccaheesch2994 is it helping the severe debilitating anxiety and depression?
What was the result of this study? It's been a year since this was posted.
Before I had long COVID in march 2020 every aging test showing was 15 years younger as I started supplements when I was 20 only and I looked that much younger too. Long COVID gave me grey hair within weeks!
Me to
i was taking a low dose of lithium orotate. between 5-10mg. it took me weeks, or months, to figure out it was responsible for the insomnia was dealing with. i couldn't get to sleep at all, wide awake most of the night. think what happened was in the beginning it wasn't having this effect, then this insomnia crept up on me and i didn't suspect the lithium which i thought would be helping sleep. i'm going back to taking it earlier in the day now
Hi thanks for sharing.
Thanks for sharing that, I just posted minutes ago how it gives me insomnia too which is very disappointing! Yes, I was wide awake too after taking 5 mg right before bed, but even if I take it in the morning I will still only get 5 or so hours sleep instead of my typical 7 hours.
@@brienq thanks for sharing as well. i took a few months off of it but just took it again yeserday morning and was able to sleep just fine. but how it may impact sleep as i continue to use it will be something to monitor. i will keep taking it in the morning and try and report back here about whether or not sleep eventually becomes effected or not
Do you think an even lower dose would work to stop insomnia?
Awesome news. I am starting low dose lithium tomorrow using lithium orotate.
Did it help?
How was your experience with it? Please let us know.
I’m not 100% certain of the benefits, but I’m feeling fine other than my freezing gait issues and diminishing voice. I will keep on taking 20 mg x2 daily.
Thank you gentlemen. 👍🏻👍🏻
Can you address concerns with lithium and kidney function? I believe there was a 2014 study saying that lithium degrade GFR but then there was a 2022 study saying lithium promotes kidney longevity. All very confusing.
It depends on the dose. Supplements generally are 10 MG or less, whereas prescription is probably 300 MG and should only be taken under medical supervision.
Hi Scott, thanks for the question, as Kitty has said it is to do with dose. Typical doses for bipolar disorder, for which it is prescribed are 300mg. Kidney issues are seen after many years at this dose. The dose here is 10 or 15 mg.
Which firm of lithium was used in the study? Carbonate, Orotate, or Citrate?
Thank you! Great to know about this. I might give my lithium 1mg for my wife to try.
Hi Ray, thanks. I hope that you find it useful.
Do doses cited correspond to elemental Li, or a salt? Thanks
In medical science they usually speak of the elemental dosage when describing the bioactive effect of an elemental compound, so it would be 10 mg of elemental Li. It's also how they label the supplement's product name, i.e., Lithium Aspartate 10 mg is referring to the Li only.
Any update on this? Can any dr write lithium?
You can buy it over the counter, lithium orotate
@@mzm8190 thank you.
So where does Prof Guttuso get funding for his long Covid study while Brad Stanfield is struggling funding his study?
Because over 100 million people have long COVID! That's more urgent of a matter than researching some anti aging drug .
No concern with sedation while sleeping? That sounds very ignorant about how important quality sleep is to brain function. Talk of sleep quality and onset of dementia is everywhere.
in this low 5 mg dose there is no signficant sedation.
There is NO sedation with 15 mg or less of Lithium Orotate.