Mannich Reaction

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  • Опубліковано 14 жов 2024
  • One of the most important name reactions is the Mannich reaction, named after German chemist Carl Mannich, who developed it in 1912. In its original form, this takes formaldehyde, an enolizable ketone, and a secondary amine, and produces a molecule with both ketone and amine functionality. Let's take a look at the mechanism of this reaction and some of its applications.
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КОМЕНТАРІ • 94

  • @dinuwarabinudithdesilva5464
    @dinuwarabinudithdesilva5464 3 роки тому +8

    Thank you professor for making valuable videos. Your italian series too helped me a lot.

  • @deadbzeus
    @deadbzeus 3 роки тому +23

    You're the best because you delve into more specialized topics, many of the great UA-cam channels cover mostly ap level.
    Thank you for everything you do professor Dave.

  • @NickSklias
    @NickSklias 3 роки тому +26

    This is the chemistry lesson I crave.

    • @NickSklias
      @NickSklias 3 роки тому +1

      @@dsullivan6842 it's like electrolytes- it's what plants crave 😆

    • @NickSklias
      @NickSklias 3 роки тому +1

      @@dsullivan6842 about once a day I get a serious hankering for chemistry knowledge. It's like a chemical dependency... I come watch this Mannich Reaction video and I'm good to go. Chemistry lessons: it's what chemistry students crave.

  • @MagicPlants
    @MagicPlants 3 роки тому

    R stands for "remainder of molecule" btw because these are considered functional groups to be added to other atoms/molecules

  • @djfrank68
    @djfrank68 3 роки тому +1

    This video should have been posted on a Monday.

  • @Varsley
    @Varsley 3 роки тому +3

    These videos are so fun

  • @TheJaxxonn
    @TheJaxxonn 3 роки тому +1

    We need a “professor Dave reaction”

  • @medicalbiochemistry_
    @medicalbiochemistry_ 3 роки тому +1

    Always Creative and Excellent

  • @Ramounskee
    @Ramounskee 3 роки тому

    wow i cant believe im subscribed to this guy since high school

  • @T3vearris
    @T3vearris 3 роки тому +1

    There is a show called Invincible and in season 1 episode 4 there is a scene with a villian making a clone. In this scene, he goes through a bunch of "lab setup" and then gets a drop of his blood(won't say how because it's awesome)and injects it into the clone lump thing. The next scene is a very rough close up of mitosis or whatever it's called, I do not know. I would like you to break down that scene because if that show is that popular, it is, how accurate is the example they give? What I get from this channel is a personal drive to exterminate misinformation and I love it. Thank you, Dave.

  • @mohamme8824
    @mohamme8824 3 роки тому +1

    very nice presentation

  • @jensgoerke3819
    @jensgoerke3819 3 роки тому

    Came via debunking, suscribed for the refresher course.

  • @MagicPlants
    @MagicPlants 3 роки тому +1

    Can you make the animations "dark mode" instead of bright white backgrounds? Like a grey bg with white structures? I would gladly help make these if you're pressed fro time.

  • @husseinfedilla6814
    @husseinfedilla6814 3 роки тому +1

    thank you please prof we want video about scope and limination of Biginnelli reaction

  • @marxistopiateaddict
    @marxistopiateaddict 3 роки тому

    i love how you try to pronounce the names correctly, as a german i really appreciate that and also you're pronouncing the names surprisingly well especially for an US citizen (no offense)

  • @moldoparkan1677
    @moldoparkan1677 3 роки тому

    I can use this reaction for the treatment of stomach ulcers and for ulcers prophylactic.

  • @vikings_fan428badatthegame2
    @vikings_fan428badatthegame2 3 роки тому

    Love your content, could you tell me more about dr. Berg? Especially about the keto

  • @morisuwa98
    @morisuwa98 3 роки тому

    Heeey Dave! 😃 how are things? Another great vid! Keep it up 👍🏻

  • @commonfactor202
    @commonfactor202 3 роки тому +3

    Hi Dave, If you had 12 molecules to take on a desert island with you, what would be those and why? It's just an idea for future videos.

  • @shikhajoshi6069
    @shikhajoshi6069 3 роки тому

    Before this video I have just mug up this whole reaction along with mechanism 🙄for my exam now finally I understood this rxn 👍

  • @thenasadude6878
    @thenasadude6878 3 роки тому +1

    She's a Mannich, Mannich reaction
    And she's alkylating like she's never done before

  • @vikramkc2219
    @vikramkc2219 2 роки тому

    Excellent lecturer

  • @DithanBeatz
    @DithanBeatz 3 роки тому

    Can you do a debunking on numerology. I feel like it's gaining popularity and have only found one other guy debunking it.

  • @YnseSchaap
    @YnseSchaap 3 роки тому +2

    Mannich reaction is touching my soul.
    I know what I want but I just don't know 😎

  • @merlin2839
    @merlin2839 3 роки тому

    thank you so much for videos it helps me learn a lot I LOVE UR VIDEOS

  • @zackandjess
    @zackandjess 3 роки тому

    Hey! Are you gonna do any debunking videos soon?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  3 роки тому +2

      I just did a big trilogy on water! Gonna take a break for a bit. Maybe in a few months.

  • @songohan393
    @songohan393 2 роки тому

    thank you

  • @anuragkunwar
    @anuragkunwar 3 роки тому

    I hope there is a way to hide the translation text. It blocks from watching the reactions on the screen. How were others able to get over this problem? It was a hindrance to watching the video for me.

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  3 роки тому +3

      Press the CC button.

    • @anuragkunwar
      @anuragkunwar 3 роки тому

      @@ProfessorDaveExplains Thank you Professor! Very surprised and exhilarated to get a response from the master himself!!

  • @Crystal_959
    @Crystal_959 3 роки тому

    Im boutta have a mannich reaction out here

  • @ALFRED_SHOOK
    @ALFRED_SHOOK 3 роки тому +2

    I don't know much about chemistry. This was fun anyway! Thanks Professor Dave!

  • @wisebuilding3079
    @wisebuilding3079 3 роки тому

    Could you make a video about the Mozart Effect? I’m not sure if it is a myth or not

  • @notmyname7698
    @notmyname7698 3 роки тому

    Make a video on ligand field theory.

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  3 роки тому +1

      I'm going to do an extensive inorganic chemistry series in the not too distant future.

  • @alansoriano3533
    @alansoriano3533 Рік тому

    Mannich reaction works with Aldehydes?

  • @backstreetfan2887
    @backstreetfan2887 3 роки тому +1

    very nice

  • @058ajaypravinbhaikukadiya9
    @058ajaypravinbhaikukadiya9 3 роки тому +1

    Put some videos on spectroscopy

  • @justalazyguy.0_0
    @justalazyguy.0_0 3 роки тому

    DOUBT:-why there are minor and major product in a parallel chemical rxn if Stoichiometry is same
    please someone explain😖

  • @MagicPlants
    @MagicPlants 3 роки тому

    Enantionmer selection = chirality control

    • @MagicPlants
      @MagicPlants 3 роки тому

      methadone is a good example

  • @abed9429
    @abed9429 3 роки тому

    lov ur tutorials

  • @ZENSLERST
    @ZENSLERST 3 роки тому

    Your voice was changed wow

  • @xl000
    @xl000 3 роки тому +1

    Do you actually know this, or is it just some stuffs copied from a reference book ?
    Meaning: without internet access, would you know all of this ?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  3 роки тому +6

      No, I am not naturally an encyclopedia of all science ever performed by the human race. Nobody is.

    • @xl000
      @xl000 3 роки тому

      @@ProfessorDaveExplains Sorry, I didn't want to be cynical or anything.
      I'm just wondering if - for example, you could spot an error in a year from now if I changed a few atoms here and there and introduced a random molecule somewhere ? I'm not sure how the whole process is discovered in the first place or anything - I'm in computer science and math, I'm not used to this. I know how to debug a program, prove the correctness of an algorithm, and so on, but I don't understand how you can derive this "Mannich reaction" from simpler chemical facts. Sorry if this sounds silly

    • @deadbzeus
      @deadbzeus 3 роки тому

      @@ProfessorDaveExplains you're a great teacher because you explain topics in such a clear way it comes off as you understanding the material thoroughly.

  • @81vintage
    @81vintage 3 роки тому

    So can we eat this mixture and trip?

  • @titobhaivlog4187
    @titobhaivlog4187 Рік тому

    Is it a electriphilic substitution reaction?

  • @dynamic9016
    @dynamic9016 3 роки тому +1

    The more I learn, the less I know.

  • @zapfilmsyt
    @zapfilmsyt 3 роки тому +1

    Interesting

  • @devilriding676
    @devilriding676 3 роки тому

    Professor Dave please will you pull apart Eric dip ass dubays Level? Please

  • @blampfno
    @blampfno 3 роки тому

    In the south they call the the Sloppy Joe Reaction.

  • @berendhol4060
    @berendhol4060 3 роки тому

    Secondary anime???

  • @MuhammadFarhan-fv2ju
    @MuhammadFarhan-fv2ju 3 роки тому

    BRUH YOU LOOK DIFFERENTT

  • @tagtag123
    @tagtag123 3 роки тому

    As opposed to the manic reaction, aka whatever my girlfriend says after I accuse her on no basis and with no training in psychology of being bipolar

  • @aabahdjfisosososos
    @aabahdjfisosososos 3 роки тому

    Can you do a video on the presidency of Trump soon? I’d think a good title for him is “The Guy Who Made Politics Relevant Again.” Would lice to see a video

  • @originalFAKEDJ
    @originalFAKEDJ 3 роки тому +1

    Finally, ketamine!

  • @gigachad2419
    @gigachad2419 3 роки тому +1

    ❤❤❤❤💓💓💓💓

  • @farisdamerji2038
    @farisdamerji2038 2 місяці тому

    OC

  • @izzamaesabado8939
    @izzamaesabado8939 3 роки тому

    💗💗💗

  • @collegeofchemistry5508
    @collegeofchemistry5508 Рік тому

    صعبة

  • @danielefosa1679
    @danielefosa1679 3 роки тому +3

    First ❤️

  • @vihaandumir1649
    @vihaandumir1649 3 роки тому +1

    13th

  • @whatsagoodusername823
    @whatsagoodusername823 3 роки тому

    Ceann don algartam

  • @cottoncube6797
    @cottoncube6797 3 роки тому

    Ur very funny

  • @tamhewitt-baker5602
    @tamhewitt-baker5602 3 роки тому

    You know you lack basic fundamentals when it sounds like a made up language. Edit. There seems to be 103 videos before this one that might help. Here goes.

  • @erbenton07
    @erbenton07 3 роки тому

    Now can you go back and explain it in English? I mean, whats the point? What practical applications of this word soup are there? Will it give my car better gas mileage or keep the valves clean? Can I use it to gt my shower door shiny and transparent again?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  3 роки тому +7

      Um, so there are these people called chemists. They do chemistry, and make all kinds of new substances, materials, and useful products. Some young people are interested in becoming chemists, so they have to learn chemistry. If you aren't, that's totally fine, but it's very odd to act dumbfounded as to why anyone else would. And don't call it "word soup" just because you don't understand it. That's also infantile.

  • @ajv2d
    @ajv2d 3 роки тому +1

    you fell off ngl

    • @ajv2d
      @ajv2d 3 роки тому

      nah i'm playing good stuff dawg

  • @galileogaming.5606
    @galileogaming.5606 3 роки тому +2

    First

  • @galileogaming.5606
    @galileogaming.5606 3 роки тому +5

    Let’s see how many subs I can gain from this comment

  • @anishagulgule04
    @anishagulgule04 Рік тому

    It doesn't feels borring when I study from ur channel... it's also the start few seconds song it's amazing learnin from u!
    Pursuing bachelor's in biotechnology,love from India🇮🇳♥️

  • @sciencenerd7639
    @sciencenerd7639 3 роки тому

    thank you