The Mannich Reaction (Mechanism + Rxn Practice)

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  • Опубліковано 17 гру 2024

КОМЕНТАРІ • 16

  • @esmaali3809
    @esmaali3809 Місяць тому +1

    Your style is simple.👏👏keep going

  • @MarcoPolo-uw7rq
    @MarcoPolo-uw7rq 8 місяців тому +1

    Dude I have my Orgo chem 2 finals in a week, and this was one one of the reactions I was having trouble with. Tyvm!

  • @ilmasumbic9197
    @ilmasumbic9197 4 роки тому +1

    Very well explained! Tomorrow I am doing practically that reaction in the lab,so I needed this for the better understanding. Thank you!!

  • @sujungchung5347
    @sujungchung5347 5 років тому +2

    This cleared up a lot of confusion. Thank you!!

  • @joeychezz
    @joeychezz 4 роки тому +2

    Great video. You are getting me through my OChem class now that everything is being taught online because of COVID-19. Thank you so much!

    • @jOeCHEM
      @jOeCHEM  4 роки тому

      Joey! From one Joe to another thank you for the kind words. I'm so glad you're finding the videos helpful. Make sure to check out my most recent live exam review joechem.io/videos/158
      And if you'd subscribe to the YT channel (if you haven't already), I'd massively appreciate it. Stay safe and good luck!

  • @terencelee8056
    @terencelee8056 4 роки тому

    Hi sir, for 3:20 part, can I say a transfer of hydride ion from NH2CH3 to OH?

  • @Nsindisogcaba957
    @Nsindisogcaba957 6 місяців тому

    But how do we know how the enol will be formed?

  • @yasmensamer7656
    @yasmensamer7656 3 роки тому +1

    Perfect!!

  • @robertopatt3510
    @robertopatt3510 2 роки тому +1

    why didnt the hydrogen leave the nitrogen in order to get rid of positive charge?

    • @alinas.2245
      @alinas.2245 Рік тому

      he mentioned that the positive charge needs to be hold in order to be able to react with the enol

    • @Corey91666
      @Corey91666 Рік тому

      i think usually you would use secondary amine instead of a primary one. like that its not that easy to get rid of the positive charge. otherwise abstracting a proton is usually not that unlikely. however abstracting a positively charged alkyle rest (is that correct in english ? german speaker here) is definitely not very likely thing to happen.

  • @valerierachaelwinter4701
    @valerierachaelwinter4701 2 роки тому

    Where did that enol come from

    • @jOeCHEM
      @jOeCHEM  2 роки тому +1

      Hi Valerie! I'm assuming you're referring to the enol at 4:42 -- if that is the case, the enol was created because the carbonyl (which here is a ketone) is in an acidic environment, which supports keto-enol tautomerism (aka the ketone flipping back and forth between its enol and keto forms).
      Let me know if that does or doesn't make sense?

    • @sadiekakenny3367
      @sadiekakenny3367 Рік тому

      @@jOeCHEM do you have to show a mechanism from the ketone to enol or can you just show that is the ketone can form an enol because it is in an acidic environment?

  • @turkkarabakh1056
    @turkkarabakh1056 Рік тому

    Sorry, but I don't understant you😐