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How do drugs affect the brain? - Sara Garofalo

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  • Опубліковано 28 чер 2017
  • View full lesson: ed.ted.com/lessons/how-do-drug...
    Most people will take a pill, receive an injection, or otherwise take some kind of medicine during their lives. But most of us don’t know anything about how these substances actually work. How can various compounds impact the way we physically feel, think, and even behave? Sara Garofalo explains how some drugs can alter the communication between cells in the brain.
    Lesson by Sara Garofalo, directed by Adriatic Animation.

КОМЕНТАРІ • 881

  • @amazingclod9304
    @amazingclod9304 7 років тому +2564

    I'm trying to take this seriously but those animations like seriously its hilarious and cute

    • @VAPOURNET
      @VAPOURNET 7 років тому +21

      Hahaha Ragdoll physics are fkin' hilariously stupid . ( bad minded ) it is freaking

    • @AB-bg7os
      @AB-bg7os 7 років тому +5

      ikr this is awesome

    • @oscarangeles6728
      @oscarangeles6728 7 років тому +4

      amazingclod it was funny when he was hitting the pookie

    • @oscarangeles6728
      @oscarangeles6728 7 років тому +3

      amazingclod I screentshoted it

    • @someonewhosinafucktonoffan1656
      @someonewhosinafucktonoffan1656 7 років тому +5

      amazingclod Looks like other people feel the same as me

  • @alumpinyourbrain
    @alumpinyourbrain 7 років тому +567

    3:20 You're not supposed to eat the pipe

    • @Fr0stBlade
      @Fr0stBlade 7 років тому +81

      Well fuck no wonder I've been having bad trips..

    • @DiamGR
      @DiamGR 7 років тому +68

      eat it for 2x effect

    • @nuclearfunk2001
      @nuclearfunk2001 7 років тому +5

      you're supposed to exhale immedietly, to avoid crystalization in the lungs, cuz dats bad. Also always brush your teeth after, or they will rot pretty quickly. And NEVER TAKE A FLAME TO YOUR ROCKS

    • @earth9564
      @earth9564 5 років тому +6

      *ssslllluuuuurrrrrppppp*

    • @bhaktaskitchen3510
      @bhaktaskitchen3510 5 років тому +6

      Lol how that guy ate the pipe 😂😂😂😂😂😂😂

  • @logane_pera
    @logane_pera 7 років тому +239

    I love this little blue guy. I'm calling him Bill.
    Have a good day Bill!

    • @thatguyfromouterspace5753
      @thatguyfromouterspace5753 5 років тому +4

      Bill is good

    • @darrenanimatic9675
      @darrenanimatic9675 5 років тому

      @@thatguyfromouterspace5753
      Well, PHERHAPS.
      jk he's a good boy

    • @rosesareb1ue
      @rosesareb1ue 3 роки тому +2

      dear people from 2017 and 2019,
      I'm kidnapping bill

    • @gaming_octopus7090
      @gaming_octopus7090 3 роки тому +2

      @@rosesareb1ue dear people of 2020
      i kidnapped bill and im gonna feed it to my babies then i’ll eat the baby lol

    • @filalieya7725
      @filalieya7725 3 роки тому +1

      This supposed to be not cute, but thatsss tooo cute

  • @rcxb1
    @rcxb1 7 років тому +549

    Did that little blue guy just eat a crack pipe, then turn into an angel with boxing gloves, and fly away?

    • @lovlelyhaha8184
      @lovlelyhaha8184 5 років тому +3

      rc xb when

    • @gray2306
      @gray2306 4 роки тому +8

      Yes, that pipe probably has something magical about it

    • @kevinshepherd6903
      @kevinshepherd6903 4 роки тому +7

      yeah this video is much more interesting on mushrooms...everything makes sense lol

    • @paingpaingpp
      @paingpaingpp 4 роки тому +3

      Haha pip goes glub glu..
      *dies*

    • @kotetsukaburagii
      @kotetsukaburagii 4 роки тому

      yuhhh get into itt

  • @x-man5374
    @x-man5374 4 роки тому +178

    Bruh they showed this at some drug/vaping presentation at my school’s auditorium today and I remember me and a few friends were holding in our laughter because how hilarious this animation looked to us. I don’t know why but at 0:38 we just burst out laughing because all we saw was a little blue thing just sliding down like it wants to die inside. Everyone else chuckled at it but we were just dying, like on the floor in tears.

    • @wolfgang5496
      @wolfgang5496 2 роки тому +2

      thats some gen z homour right there my guy

    • @leetlbt
      @leetlbt 2 роки тому +2

      Where yous stoned are something 🤔 cos its not funny.

    • @derickzon3347
      @derickzon3347 2 роки тому +1

      @@leetlbt very likely withraul afects

    • @Amin10XD
      @Amin10XD Рік тому

      It's not funny or hilarious. Something is wrong with you & your friends.

    • @x-man5374
      @x-man5374 Рік тому +1

      @@Amin10XD ur just not fun at parties chief

  • @yessir3944
    @yessir3944 7 років тому +1898

    animation is top kek

    • @ScorpoCorpo
      @ScorpoCorpo 7 років тому +10

      The Guy Who Comments Cool name, bro.

    • @razvanradoiu
      @razvanradoiu 7 років тому +23

      "kek" found the virgin

    • @yessir3944
      @yessir3944 7 років тому +8

      Răzvan Rădoiu prof pic tho 🤔

    • @riepie
      @riepie 7 років тому +2

      Răzvan Rădoiu That's racist

    • @carlsanders7921
      @carlsanders7921 7 років тому +5

      Idk top kek is a big deal, I didn't splooge so idk if it's top kek but it's high on the scale

  • @MusicMyLife1004
    @MusicMyLife1004 7 років тому +211

    Am I high, or is the animation just so... intriguing

    • @cestalia
      @cestalia 7 років тому +22

      Arya Stark who needs drug when you're high on animation?

    • @Infinityc702
      @Infinityc702 2 роки тому

      There’s also a video on how smoking affects the body and it involved getting high.

  • @mathewthomas6694
    @mathewthomas6694 Рік тому +7

    3:26:
    The way he ascends like that oh my god I'm dying

  • @j3d650
    @j3d650 7 років тому +1075

    I SNIFF OXYGEN

    • @hollykoll8999
      @hollykoll8999 7 років тому +19

      Jed Rivera me too bruh

    • @DavidLopez-zy9ei
      @DavidLopez-zy9ei 7 років тому +10

      Jed Rivera #Savage

    • @farkrad1970
      @farkrad1970 7 років тому +40

      Jed Rivera This is very dangerous because once you start sniffing oxygen you can't stop, plus most of the addict dies during detox.

    • @sizzlinsj8135
      @sizzlinsj8135 7 років тому +46

      Its dangerous because almost all the people who died inhaled oxygen in their lifetime 😓

    • @alexwang982
      @alexwang982 7 років тому +2

      Jed Rivera spaace!

  • @willstr88
    @willstr88 7 років тому +200

    *Looks at title*
    Me: "How do drugs affect the brain?"
    Me: Huh...
    *Looks at thumbnail*
    Me: Well, it looks like I'm already on drugs

  • @agochk01
    @agochk01 7 років тому +70

    Let's give a moment of silence to appreciate how fluently the narrator is saying these words.

  • @johnkeleher5563
    @johnkeleher5563 Рік тому +12

    I've heard so many wonderful things about magic mushrooms but I can't easily get some, Is there any realiable source I can purchase from??

    • @annamason3087
      @annamason3087 Рік тому

      I'm so interested in the experience but am terrified of having a bad trip

    • @sebastianfelipe515
      @sebastianfelipe515 Рік тому

      I did two grams last time, it was a thrilling experience and I enjoyed it

    • @odentenzin3129
      @odentenzin3129 Рік тому +1

      ( dream.spores). S. Jason
      Got psych's**

    • @annamason3087
      @annamason3087 Рік тому

      This whole thing is pretty new to me, can I try 3grams?

    • @sebastianfelipe515
      @sebastianfelipe515 Рік тому

      @@odentenzin3129 where to search? Is it IG ??

  • @neverending9803
    @neverending9803 7 років тому +81

    I understood everything until neurotransmitters, then I just watched the rest while being pleased by the animation. It was a great video and I'm really interested in this but I don't know why I've been loosing focus so quickly. I will rewatch this tomorrow as I really want to understand it. I enjoy this kind of content on UA-cam and look forward to more videos.

  • @jayakrishna2154
    @jayakrishna2154 5 років тому +10

    One of the crystal clear explanations available to me in my life is TED-Ed...

  • @WeArePharmers
    @WeArePharmers 7 років тому +109

    Excellent basic breakdown, I wish I could show this to all my patients.

    • @symonefiguracion
      @symonefiguracion Рік тому +2

      why can't you?

    • @ronlacker326
      @ronlacker326 Рік тому +3

      @@symonefiguracion Cause they're rug addicts. They can't stand the truth.

  • @2kidshavingfun
    @2kidshavingfun 7 років тому +96

    The animation is rly cool

  • @cd.s.82
    @cd.s.82 7 років тому +1

    The animations are bubbly, rounded-out, and nice, and I like it.

  • @katherineelizabeth7177
    @katherineelizabeth7177 7 років тому +6

    this animation is the best thing I've seen all week pls do all videos like this forever

  • @ahsanghumman4497
    @ahsanghumman4497 3 роки тому +2

    Excellent video,,,explained many complex concepts in a very short time.

  • @fandomfangirl5264
    @fandomfangirl5264 6 років тому +18

    The blue animated character is just so cute ❤💙💚💛💜💓💕💖💗💘💝💞💔💟

  • @mrblablo1
    @mrblablo1 7 років тому +25

    I love the animation, made me laugh a few times. I hope you guys use it or do something like it again.

  • @victortassi4397
    @victortassi4397 4 місяці тому +1

    I'm in Pharmaceutical School and there are so many little details to every single thing the video talks about...I miss it when learning about drugs and medicines was as simple as a TED Video 😭

  • @RixMorales
    @RixMorales 7 років тому +28

    I happened to watch an episode in Breakthrough S02 in National Geographic Channel where LSD was used to combat any form of addiction (drug, alcohol, tobacco). The results were kind of promising as the subjects of the treatment reported better mental state and were able to put their addiction at bay for several months

    • @Sonuxr_
      @Sonuxr_ 2 роки тому

      Yes I have watched it too

  • @aqstarrzz415
    @aqstarrzz415 3 роки тому +4

    Beautifully explained....👏👏👏

  • @ianonymous6106
    @ianonymous6106 7 років тому +1

    love what you do for us.......i watch every video that i can

  • @Marina-ly6zy
    @Marina-ly6zy 7 років тому +422

    the animation is nice

    • @kamalakhan3586
      @kamalakhan3586 7 років тому +6

      the animation is nice

    • @samdes9119
      @samdes9119 7 років тому +5

      The animation is nice

    • @ashw8495
      @ashw8495 7 років тому +4

      the animation is nice

    • @athanasia222
      @athanasia222 7 років тому +3

      Galaxy Unicorn the animation is nice

    • @jeshand3159
      @jeshand3159 7 років тому +4

      the animation is nice

  • @KawaiiHippityHop-cl5bb
    @KawaiiHippityHop-cl5bb 2 роки тому +2

    I love the cute blue cat-looking thing in the video, it’s just TOO cute.

  • @Lightning_Toad
    @Lightning_Toad 7 років тому +1

    I really love the animation in this video.

  • @user-cd4bx6uq1y
    @user-cd4bx6uq1y 8 місяців тому +1

    I've been getting a ton of "drugs experience explained" out of nowhere in my reccomendations, so at least I'll watch these

  • @elizxbeth1
    @elizxbeth1 4 роки тому +1

    Thanks for helping me with my homework

  • @eocalive
    @eocalive 7 років тому +3

    thank you for sharing another great video ted ed

  • @MPV_Puneeth
    @MPV_Puneeth 7 років тому

    great illustration..sir

  • @imandac.3737
    @imandac.3737 3 роки тому +9

    This 5 min explanation answered all my confusions than the school does in days lol

  • @LegoCookieDoggie
    @LegoCookieDoggie 7 років тому

    I love this smooth animation!

  • @dave6222
    @dave6222 7 років тому +62

    ted ed can explain shit very well, Ted ed you're doing a great job

  • @sayAlhamdulillah99
    @sayAlhamdulillah99 4 роки тому +1

    I love the animation so muchhhh 10/10!!

  • @deepdishattack
    @deepdishattack 7 років тому

    I love the animation style

  • @pierreschelling213
    @pierreschelling213 4 роки тому

    very well done

  • @psychedelicc
    @psychedelicc 7 років тому

    the animation is so awesome

  • @NeriDompiericchio
    @NeriDompiericchio 7 років тому +1

    fantastic animation!

  • @BeefyBastardy
    @BeefyBastardy 5 місяців тому +1

    My project partner and I were clowning on the animation but the info was so useful to us that we had to use in💀💀😭

  • @johnnyyu8392
    @johnnyyu8392 7 років тому

    Love the animation.

  • @idontwanttotellyou2554
    @idontwanttotellyou2554 7 років тому

    I love this animation.

  • @riverhope4299
    @riverhope4299 7 років тому

    The animation is so adorable and funny that I can barely focus on the information. Why am I like this? XD

  • @IndieSamurai101
    @IndieSamurai101 7 років тому +1

    Animation is top notch!

  • @vipinjamwal1522
    @vipinjamwal1522 5 років тому +1

    Best animation + best information = ted ed

  • @Filaqosik
    @Filaqosik 7 років тому +57

    oh, greater soul gems are also a drug?

    • @Yolen16
      @Yolen16 7 років тому +5

      you always need more xD

  • @sr2193
    @sr2193 4 роки тому

    Excellent video! Absolutely

  • @juanestebanacostagutierrez8950
    @juanestebanacostagutierrez8950 7 років тому +4

    they had already made a video about this. it's called How does your body process medicine.

  • @oakleyjacket7922
    @oakleyjacket7922 7 років тому

    I frikkin love this animation.

  • @sarveshkumaryadav5114
    @sarveshkumaryadav5114 3 роки тому

    Awesome animation effect... 👌👌

  • @MLMLML000
    @MLMLML000 7 років тому

    I knew about this before but i still learned some cool names!

  • @mariposahunter9737
    @mariposahunter9737 7 років тому

    I loved the animation of this video :D

  • @LucasPereira-iy6rb
    @LucasPereira-iy6rb 7 років тому

    It's really useful for improving my English.

  • @jayantzalki8039
    @jayantzalki8039 3 роки тому

    Liked the animation style 👌

  • @suyiyu8471
    @suyiyu8471 8 місяців тому

    The animation is like so good!

  • @naomikorem4338
    @naomikorem4338 7 років тому +10

    I think it will be interesting if you make a video about ADHD drugs like Ritalin or Adrel and how they're work

  • @gorannovaks
    @gorannovaks 7 років тому +16

    we need more rigid body physics in biomedical animations, looks unusually amusing

  • @lazerlightsub
    @lazerlightsub 7 років тому +14

    I learned more than what I learned in school for the last year, from this video.

    • @dillonmyers965
      @dillonmyers965 2 роки тому +1

      For reallllllll

    • @nazarruulhaqi4046
      @nazarruulhaqi4046 2 роки тому +1

      You should increase your attention span

    • @z0864
      @z0864 Рік тому

      @@nazarruulhaqi4046 its more about the teachers teaching and the way of teaching rather then the attention span

    • @starrykailani
      @starrykailani Рік тому

      I watched this at school

    • @julianbates
      @julianbates Рік тому

      no way man, that's crazy!!

  • @gabbydeveyra1571
    @gabbydeveyra1571 7 років тому

    and again the animation is great

  • @PhysicsVlogs
    @PhysicsVlogs 7 років тому

    wow, lovely animation!

  • @shammas371
    @shammas371 3 роки тому

    I got shivering by seeing this

  • @curiousbekishiferaw6003
    @curiousbekishiferaw6003 7 років тому

    excellent video.

  • @NeXt3895
    @NeXt3895 7 років тому

    I LOVED THE ANIMATION

  • @vincentkhang5264
    @vincentkhang5264 7 років тому +399

    When you're this early, there are no good comments because everyone's fighting to type "first"

    • @lecoureurdesbois86
      @lecoureurdesbois86 7 років тому +6

      Vincent Khang and the usual 20 people all claiming they are first

    • @vincentkhang5264
      @vincentkhang5264 7 років тому +1

      Z1RCONIUMx911 exactly lol

    • @sanjanasoni2262
      @sanjanasoni2262 7 років тому +12

      Vincent Khang , after that their are people claiming for second and third,.

    • @diyseeker3547
      @diyseeker3547 7 років тому +6

      Vincent Khang What is wrong with UA-cam, it says it was posted 31 min ago but you posted this comment 32 min. Gosh your early you said this before it was posted lol.

    • @-_Somebody_
      @-_Somebody_ 3 роки тому

      @@diyseeker3547 oh stop, I’d rather go back to 2017 where you are than be in 2020 😂

  • @RixMorales
    @RixMorales 7 років тому +7

    I love the voice of narrator. He can instantly calm my nerves. He's better than most ASMR artists I've ever watched.

    • @RixMorales
      @RixMorales 7 років тому +2

      Also, OMG the animation is so cute!

  • @eduardobarreto5555
    @eduardobarreto5555 7 років тому

    I watched this video 5 times just because of the cute animations. Good job!

  • @martonbalassa8128
    @martonbalassa8128 7 років тому +32

    @3:50 Psychedelics BLOCK the release of serotonin? Can we have a source on this? In every publication I have ever read, these molecules are described as serotinin agonists, that is, a molecule that is similar to serotonin, and binds to serotonin receptors, so the effect is not due to blocking serotonin, but exciting these neurons by mimicking it.

    • @ModdedLu
      @ModdedLu 7 років тому +14

      Márton Balassa that pissed me off also. He should've also mentioned Shrooms, which have been proven to almost cure depression. No sources though 😠

    • @paulrogers5105
      @paulrogers5105 5 років тому +2

      @@ModdedLu I just mentioned that in response to another comment the benefits of shrooms are amazing and we're just learning about them them

    • @postymusic4387
      @postymusic4387 2 роки тому

      @@ModdedLu Psylocibin cures depression

  • @igorwaite3085
    @igorwaite3085 7 років тому

    I love Learning new things about brain chemistry. And learning new things release dopamine.

  • @fishstixs7805
    @fishstixs7805 7 років тому

    I love the animation

  • @Phartonium
    @Phartonium 7 років тому

    I love this animation :)

  • @RammusTheArmordillo
    @RammusTheArmordillo 7 років тому +44

    Cut the sound, play psychedelic music and you get the best clip of 2017

    • @belladmazz6942
      @belladmazz6942 6 років тому +1

      RammusTheArmordillo ha I was jus trying to imagine wha that would look like!

  • @highTideWaves
    @highTideWaves 7 років тому +2

    It's 11:30pm but then I see a ted-ed video uploaded... Have to watch this before sleeping lol

  • @dogarucos
    @dogarucos 7 років тому

    The animation fits perfectly

  • @beatrizhelena6204
    @beatrizhelena6204 7 років тому

    THIS ANIMATION IS SO CUUUUTEEEE

  • @warriors_of_light5559
    @warriors_of_light5559 5 років тому +3

    Very quick and detailed, thank you!:)

  • @alinadiaz6625
    @alinadiaz6625 5 років тому

    This is useful for my science fair project

  • @prairiet.t.3447
    @prairiet.t.3447 7 років тому

    BEST ANIMATION where can i buy merch

  • @simratsingh4154
    @simratsingh4154 7 років тому

    dope animation

  • @MarkWaner
    @MarkWaner 7 років тому

    Cool animation! Like it!

  • @redbruhcolli
    @redbruhcolli 7 років тому

    Filip nails these animations!

  • @mrmemes7883
    @mrmemes7883 5 років тому

    Best joint animation

  • @frawgs
    @frawgs 7 років тому

    kudos to the animator, these 3D animations are awesome!

  • @muhamadazamuddin5925
    @muhamadazamuddin5925 7 років тому

    I'm waiting for the results to come out & hoping that I can get at least A- for Pharmacology...

  • @jordynelliott6712
    @jordynelliott6712 7 років тому +2

    *Came for the knowledge*
    *Stayed for the animation*

  • @slwm9741
    @slwm9741 Рік тому +3

    Watching this 20 mins before my exam 😂

  • @selifiaib1657
    @selifiaib1657 7 років тому

    Lovely !

  • @-_Somebody_
    @-_Somebody_ 3 роки тому

    Solid video, I’ll show my son.

  • @XXCoder
    @XXCoder 7 років тому

    Awesome video, I just hate the wandering camera effect.

  • @kindofart9369
    @kindofart9369 6 років тому

    Thnk youu ♡

  • @ninaerazo7409
    @ninaerazo7409 5 років тому

    Super Cute hehe and really like the information too, thank you for sharing...I wish I could do some animations like that for classes hehe

  • @TrueInvisible
    @TrueInvisible 7 років тому

    nice new animation!

  • @madcat789
    @madcat789 7 років тому

    Awesomely.

  • @symonefiguracion
    @symonefiguracion Рік тому

    cool animation

  • @cup_check_official
    @cup_check_official 7 років тому +153

    but my question is, does it reach your brain quickly if you inject it in your neck as compared to injecting it in your leg? just for scientific purposes. promeeeese

    • @polandball3076
      @polandball3076 7 років тому +3

      Tell Me This it takes 2 min longer in ur example so yes

    • @user-pj8tr3oc8s
      @user-pj8tr3oc8s 7 років тому +112

      Tell Me This If it's injected in a vein (intravenously), it won't make much of difference since both injection sites lead to very rapid distribution of the drug in the blood stream. However, if you inject the substance in fat tissue under the skin (usually the case when drugs are being injected in the leg), then it will have a much slower effect because it has to reach the blood stream by diffusion first before it can take action in the brain.
      Source: I'm a pharmacist

  • @rishabhrana5529
    @rishabhrana5529 7 років тому

    do a video on derivatives

  • @apophis2129
    @apophis2129 Рік тому +9

    I'm of the opinion that psychedelics have the potential to bridge the gap between what we think of as the material world and our "souls". There really needs to be a lot more research done, and the "war on drugs" really screwed any notion of understanding the intricacies of these substances, and how people could use them to better understand the spiritual elements of the experience and gain a deeper understanding of what dictates the motion of our spirits and personalities.

    • @user-jh4yx3sw2q
      @user-jh4yx3sw2q 9 місяців тому

      No, I have taken acid, and it just makes you understand the universe, it taps into knowledge and understanding, not the soul.

  • @shaqilamin6345
    @shaqilamin6345 7 років тому

    Thank for the weekly dose of useful information I will never use TedEd :' )

  • @victortassi4397
    @victortassi4397 4 місяці тому

    0:24 NOT THE FIGHT-OR-FLIGHT ANIMATION 😂😂

  • @yosoyjoe123
    @yosoyjoe123 2 роки тому

    Really cool I'm watching this awesome learning vid while sniff'n on my room👽 makes one of kind experience lol