MTT assay | Cell Viability and Cytotoxicity determination using MTT assay

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  • Опубліковано 5 лют 2025
  • This video talks about MTT assay and answers following questions like:
    How MTT assay is done?
    How does MTT assay determine cell viability?
    What is MTT assay cancer?
    What is MTT assay used for?
    What are advantages and disadvantages of MTT assay?
    How do you use MTT test?
    Why is determining cell viability important?

КОМЕНТАРІ •

  • @SaraTommat
    @SaraTommat 3 роки тому +22

    This was awesome, you took the major concepts and gave a quick overview of how they connect which makes it easier to understand

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      Thanks a lot Sara for your feedback, please share my channel link with your friends and help me to reach big audience

  • @aliyaa6156
    @aliyaa6156 2 місяці тому

    i love you king i was so confused trying to write my lab report for 2nd year biochem, but this saved me and i understand the content so much more now

  • @grw2429
    @grw2429 3 роки тому +11

    First of all, thankyou for making this content. It helps me a lot during uni 😭👍🏻 You make it so simple and easy to understand

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +2

      Please share my channel with your friends and help me to reach big audience..lots of love from India

  • @nancymalhotra6734
    @nancymalhotra6734 4 місяці тому +3

    Very helpful video (animations). Helped me clear my concepts. God bless you❤

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 місяці тому +1

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @xieruiyun5633
    @xieruiyun5633 3 роки тому +5

    waooo unbelievable~you really made this video so quickly.I really appreciate all your effort. Well done sir!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      Please share my channel link with your friends and help me to reach big audience

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      Don't forget to leave your suggestions

    • @xieruiyun5633
      @xieruiyun5633 3 роки тому

      @@animatedbiologywitharpan sure sure,I will try my best to share your working for many people .

  • @randompan1112
    @randompan1112 Рік тому +2

    This video is really helpful. Thank you for your wonderful presentation, it really helped me in my research study

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

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  • @srijandey87
    @srijandey87 3 роки тому +2

    Ur videos are really a way better and lucid than other youtubers 🧡❤

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      Please share my channel link with your friends and help me to reach big audience

  • @iftikharansare870
    @iftikharansare870 2 місяці тому +1

    Very helpful video sir..Thankuu

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 місяці тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @nooraks6032
    @nooraks6032 Рік тому +1

    Thank u.. clear and very beauty explain

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      Please support our channel by using super thanks. Your 2$ donation would give us motivation to do more. Super thanks option is present below any of my videos, a heart sign with $ in it.

  • @hamidakhatun2139
    @hamidakhatun2139 2 роки тому +1

    Such an awesome video..thank you so much💓💓

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +1

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
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  • @Mohamedyasar1234
    @Mohamedyasar1234 2 роки тому +1

    Amazing explanation sir.thank you so much sir.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.

  • @sirappo4336
    @sirappo4336 Рік тому +1

    Honestly this was so much clear and helpful ! thank you very much you are amazing !!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      It's very difficult for us to run the channel financially. Please support my channel via super thanks. Your small contribution like 1$ means a lot for us. The super thanks option is present at the lower right corner of any video, a heart sign with $ in it.

  • @norhadimohamad3667
    @norhadimohamad3667 2 роки тому +2

    very clear and simple explanation. love it
    :)

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Really glad to know it was useful. Please share my channel with friends. You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @samuelbrown9665
    @samuelbrown9665 2 роки тому +1

    Arpan, your videos are incredible, please keep going!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.

  • @leonellumogdang7313
    @leonellumogdang7313 3 роки тому +2

    Thank you for making this video. it really helps.

  • @mahabharathi7236
    @mahabharathi7236 2 роки тому +2

    very useful thankyou sir

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.

  • @dr.muhannadal-qahtani7367
    @dr.muhannadal-qahtani7367 4 місяці тому +1

    Very helpful video, Thanks

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 місяці тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @kochutheresaa
    @kochutheresaa 2 роки тому +1

    Nice lecture sir.. Useful 😇

  • @leanswagger5822
    @leanswagger5822 3 роки тому +2

    Bro, amazing animations and explained very well!

  • @EmilyBenson1998
    @EmilyBenson1998 2 роки тому +1

    Very well-detailed video!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Glad to hear that it wad useful. You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @Proudly_Nothing
    @Proudly_Nothing 10 місяців тому +1

    Thank u for such good concepts
    Appreciate it

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  10 місяців тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

    • @Proudly_Nothing
      @Proudly_Nothing 10 місяців тому

      @@animatedbiologywitharpan ofcourse man I will . Keep up the good content

  • @sarahsabrina1310
    @sarahsabrina1310 2 роки тому +2

    Thank you so much sir for your time and effort :D a very interesting video and it helps me a lot to do my research in my undergraduate study.

  • @rajarshibose3318
    @rajarshibose3318 7 місяців тому +1

    Great sir.Thank you so much

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  7 місяців тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  7 місяців тому

      @@rajarshibose3318 checkout our techniques in biology playlist.

  • @RohitPant04
    @RohitPant04 2 роки тому +1

    That "Hellow!" at the start of your videos is my energy drink these days. Haha!

  • @ammarahchaudhary2820
    @ammarahchaudhary2820 2 роки тому +2

    Nice lecture ,
    Sir plzzzzzz explained cell revival,cell subculturing ,cell culture , splitting and passaging etc Also with protocol.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on Instagram as @animatedbiologywitharpan. Install the app to follow my photos and videos. instagram.com/invites/contact/?i=1p41h314q3fv8&

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Cell culture playlist ua-cam.com/play/PLKtiwIJ8Q7rpNrZRxzBgoH2Q6oz4bJwg2.html

    • @ammarahchaudhary2820
      @ammarahchaudhary2820 2 роки тому +1

      Thanx sir for your reply .
      Keep it up for making such a nice videos
      Plz recommend any good book for cell culture protocol related.

  • @Belikeabutterfly-v7z
    @Belikeabutterfly-v7z 2 роки тому +1

    We need more of such clips ... very informative and concise

  • @fatemetaheri9132
    @fatemetaheri9132 2 місяці тому

    Great thanks very much

  • @MilindChatrabhuji
    @MilindChatrabhuji 2 роки тому +3

    Thank you for this video.
    I need to have cytotoxicity studies done for several samples of mercury sulphide on healthy cell lines of liver and kidney. Can you help me on where this can be done and what may be the approximate cost? Thanks in advance.

  • @mohanbotany8691
    @mohanbotany8691 5 місяців тому +1

    Please tell me cells seedling calculation

  • @BlackHorse7K
    @BlackHorse7K 3 місяці тому +1

    Thank you

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 місяці тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @shilat1234
    @shilat1234 2 роки тому +3

    Nice video :)
    Where are you get the animations (the little pictures)? Is there a website link?

  • @hudanoor6009
    @hudanoor6009 2 роки тому +1

    Sir can you make a video on cell invasion and migration assay

  • @ΓεώργιοςΖαμάνης
    @ΓεώργιοςΖαμάνης 2 роки тому

    I would like to ask if the reduction of tetrazolium takes place in the cytoplasm or in the mitochondria, i.e. the dye also penetrates into the mitochondria

  • @vinzky89
    @vinzky89 2 роки тому +1

    Thank you so much !!!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance

  • @ggsutelzi4236
    @ggsutelzi4236 2 роки тому +1

    Can i use this technique to measure cell viability after autolysis of E. Coli??

  • @spacebound05
    @spacebound05 2 роки тому +1

    Thank you so much 😭👍🏻

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance

  • @Mazykibite
    @Mazykibite Рік тому

    Please make vedio on Oecd guidelines 407, 408, 409, 410 and on Neutral Red assay

  • @ievavain
    @ievavain 2 роки тому +2

    Hello! so does MTT and LDH assays both use yellow tetrazolium salts that get converted into formazan? why is formazan produced different colours? is it bc in mtt the tetrazolium salt contains bromide (MTT) and in LDH - iodine (INT)?

  • @pratikbebektarifleri
    @pratikbebektarifleri 2 роки тому +1

    Must we wait 2 hours after adding DMSO?

  • @Crackheads305
    @Crackheads305 3 роки тому +1

    Is it a biochemical test

  • @milkskp9545
    @milkskp9545 2 роки тому +1

    what did you put in the control and treatment

  • @dhananjaydas5934
    @dhananjaydas5934 3 роки тому +1

    Thank you so much Sir... Sir can you please explain the Annexin V fitc experiment

  • @md8552
    @md8552 2 роки тому +1

    thank you sooo much

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.

  • @ammaarfirdauz
    @ammaarfirdauz Рік тому +1

    Thanks arpan

  • @kvnkvn9191
    @kvnkvn9191 3 роки тому

    How we can generate standard curve or
    how we know that how much cell are viable in or standard?
    🤔

  • @truthwill3
    @truthwill3 4 місяці тому +1

    thank you :)

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 місяці тому

      @@truthwill3 Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @aondohembanege9551
    @aondohembanege9551 11 місяців тому +1

    Hi, thanks for the video. Please, I have a question: I will like to ask a question about cell treatment experiment with a test drug for 72 h. In such an experiment, do I have to add my drug once and incubate for 72h then check the cell viability or I have to remove the drug solution and replace with the same drug and concentration after each 24h to avoid wrong readings due to degraded drug in wells or evaporation? Please any other person reading the comments can also reply me if you have the correct answer to my question. Thank you

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  11 місяців тому

      It depends on bioavailability. If the drug is degraded within a day then it has to be added multiple time.

    • @aondohembanege9551
      @aondohembanege9551 10 місяців тому +1

      Thank you very much for taking out time to respond to this my question here. I really appreciate it @animatedbiologywitharpan

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  10 місяців тому

      thanks for the kind words@@aondohembanege9551

  • @auroredega403
    @auroredega403 2 роки тому +1

    thank soo much

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @rootsnstems65
    @rootsnstems65 3 роки тому +1

    Very nice and easy explanation. Pls let me how to making this slide in ppt?

  • @panuwitkamwong3108
    @panuwitkamwong3108 4 місяці тому +1

    Cat we use MTT assay for investigation of IC50 ?

  • @JayantPadwal
    @JayantPadwal Рік тому +1

    On which website I will find this information in written ?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      www.sigmaaldrich.com/IN/en/technical-documents/protocol/cell-culture-and-cell-culture-analysis/cell-counting-and-health-analysis/cell-proliferation-kit-i-mtt

  • @ying2694
    @ying2694 2 роки тому +1

    What are the material and chemicals required for this experiment?

  • @dhanashreeshirsat8416
    @dhanashreeshirsat8416 Рік тому +1

    When drug is added into it

  • @BigDaddyGelo
    @BigDaddyGelo Рік тому +1

    Hi, I have a question regadring with MTT assay😃

  • @soundaryaudaiyar6965
    @soundaryaudaiyar6965 2 роки тому +1

    Which app did you use?

  • @prachitywankhade798
    @prachitywankhade798 2 роки тому +1

    It has really helped me a lot in understanding the test report of my research samples. Please let me know in which stage does the treated sample extract come in contact with the cells

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Please share my channel link with your friends. Glad to know that it was useful for you

  • @WebbLuther
    @WebbLuther 4 місяці тому +1

    673 Dalton Mountain

  • @masomahnejati9272
    @masomahnejati9272 3 роки тому +1

    🙏🙏👏

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      Please share my channel link with your friends and help me to reach big audience

  • @MackintoshWright
    @MackintoshWright 4 місяці тому +1

    5657 Abshire Skyway

  • @saltlake4098
    @saltlake4098 10 місяців тому

    Cancer, apoptosis, metabolic activity of cell- MTT assay

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  10 місяців тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @BettyHall-m6c
    @BettyHall-m6c 4 місяці тому +1

    Dickinson Green

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 місяці тому

      @@BettyHall-m6c Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @aina7600
    @aina7600 Рік тому +2

    Y we call it MTT ?

    • @Sheraz484
      @Sheraz484 Рік тому +5

      Because of the dye which is used in this procedure,"Tetrazoleum" which is short form of 3-(4,5-diMethylThiazol2-yl)-2,5-diphenylTetrazoluem bromide simply, MTT

    • @amanverma2611
      @amanverma2611 5 місяців тому

      Because Umtiti

  • @DanielRobinson-p1e
    @DanielRobinson-p1e 4 місяці тому +1

    Christa Camp

  • @santoshkumari161
    @santoshkumari161 3 роки тому +1

    Sir can you tell me how i find IC50 value from the standard curve of this assay

  • @LouiseLegault-w6z
    @LouiseLegault-w6z 5 місяців тому +1

    Edna Shoals

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 місяців тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @LeoTrenton-c8j
    @LeoTrenton-c8j 5 місяців тому +1

    Koch Glen

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 місяців тому

      Please support our channel by using super thanks. Your 2$ donation would give us motivation to do more. Super thanks option is present below any of my videos, a heart sign with $ in it.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 місяців тому

      Please support our channel by using super thanks. Your 2$ donation would give us motivation to do more. Super thanks option is present below any of my videos, a heart sign with $ in it.

  • @MarenAmore-e3f
    @MarenAmore-e3f 5 місяців тому +1

    Jolie Village

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 місяців тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @JennieHall-j1s
    @JennieHall-j1s 5 місяців тому +1

    Milo Haven

  • @MichelleLopez-s5t
    @MichelleLopez-s5t 4 місяці тому +1

    Senger Hollow

  • @lakshaygarg3473
    @lakshaygarg3473 2 роки тому +1

    Can you tell me what is the function of DMSO?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +2

      DMSO is added at the end of the reaction to dissolve the formazan crystals formed from the reaction. Otherwise, you can not properly measure the color density of the reaction. DMSO is added only after incubation with MTT dye.

    • @salaheddine3041
      @salaheddine3041 2 роки тому

      but DMSO has an antibacterial effect, will this ruin the experiment when using e.coli strains for example ?

  • @DanielKell-s8o
    @DanielKell-s8o 4 місяці тому +1

    Devonte Square

  • @ViralStuffs9999
    @ViralStuffs9999 9 місяців тому

    can u please share your slides

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  9 місяців тому

      you can buy it @5$ , please emailis at arpanparichha1994@gmail.com for more details