USMLE STEP 1: PHARMACOLOGY (VIDEO 3) - METABOLISM (INDUCERS & INHIBITORS)

Поділитися
Вставка
  • Опубліковано 15 сер 2020
  • ESSENTIAL MATERIALS
    www.amazon.com/shop/randyneilmd.
    Disclaimer: As an Amazon Associate I earn from qualifying purchases. There is no additional charge to you.
    USMLE STEP 1: PHARMACOLOGY (VIDEO 3) - METABOLISM (INDUCERS & INHIBITORS). This is the 3rd video in a series for basic concepts for STEP 1 Pharmacology.

КОМЕНТАРІ • 141

  • @SuperEditz-j9v
    @SuperEditz-j9v 3 роки тому +11

    Hi Dr Randy, I would like to point out that Quinidine is enzyme inhibitors and isoniazid is enzyme inducer.

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому +5

      I'll go ahead and PIN this... I thought I had mentioned that in the video...or maybe in the first version. I thought I had mentioned the change of Quinidine in the newer FA...

    • @eyybby1
      @eyybby1 3 роки тому +10

      @@RandyNeilMD where do you see isoniazid is an inducer? In FA 2020 it’s still under inhibitor

    • @dr.insitu6455
      @dr.insitu6455 3 роки тому +11

      @@eyybby1 INH is inhibitor, you are correct!

    • @abduldanish6112
      @abduldanish6112 3 роки тому +4

      @@dr.insitu6455 INH is never a inducer till yet.

    • @sleepytraveler369
      @sleepytraveler369 3 роки тому

      @Mohammed Alfred you're right, nobody gives a shit

  • @chetanreddycds
    @chetanreddycds 4 роки тому +9

    Hi Dr Randy, first thing i do in the morning is to watch your video and continue my study :)

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому +1

      Chetan... KEEP MOVING FORWARD!!

  • @Knstar5566
    @Knstar5566 4 роки тому +15

    I really like this pharmacology videos, you always make easier for everyone, thank you so much.

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому +2

      Thank you Musawair... Keep studying HARD!!

  • @MedicalBlackBook
    @MedicalBlackBook 3 роки тому +2

    Your so nice 😢 "be able to teach the next person" the sweetest gesture.

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      Thank you for taking time to comment. Appreciate the kind words.

  • @1DOLLARS1828
    @1DOLLARS1828 3 роки тому +3

    Missing and more missing the awesome Videos Docs.. No worrie about errors .. you are the best that's all.. ..You are doing Great and perfect for the beginers like us ..

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому +2

      Abali, Thank you for the kind words... No worries... just a small break. Trying to balance work, videos, everything... I know what it feels like to struggle...so I will be back to help.

  • @SA-jm1mm
    @SA-jm1mm 3 роки тому +1

    Thank you so much Dr. Randy.Great videos, please keep doing them!

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      Dr. SA, Thank you for commenting.

  • @goldenkeys3
    @goldenkeys3 3 роки тому +5

    Hi Dr. Randy! You're literally AMAZING. Thank you so much for sharing your knowledge. STEP 1 is next week for me and now I'm feeling confident! THANK YOUUU

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      Ivy, CONFIDENCE is KEY. It is...

  • @randomone3858
    @randomone3858 3 роки тому +4

    By watching your videos everything makes sense more and more

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому +1

      Izhar, I'm glad these have been helpful.

  • @mariagabrielazuritamontano8083
    @mariagabrielazuritamontano8083 3 місяці тому

    Simplemente amo! tu contenido thank you!!

  • @hazazihazazi4204
    @hazazihazazi4204 4 роки тому +3

    Dr. Randy new video is the best youtube notification

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому

      Hazazi, Too kind... I appreciate your comment. Thank you.

  • @user-hk4zr4nr3g
    @user-hk4zr4nr3g 4 роки тому +4

    Dr Neil thank you very much for amazing lectures! Because of you I started to understand much better biostatics and pharmacology! From Russia with love!

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому

      You are most welcome. Glad it was helpful.

  • @princessz5087
    @princessz5087 4 роки тому +5

    By reviewing the notes and going over the questions really help me remember the topics much easier. Thank you so much!

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому

      Princess Z, Thank you again for your comment and feedback. Much appreciated.

    • @anoshakhan2067
      @anoshakhan2067 2 роки тому

      Hey could you please send me the notes as well my exam is this month!

  • @sangayongmu2962
    @sangayongmu2962 4 роки тому +5

    You always hit on the most confusing topics! Thank you 🙏

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому +1

      Sangay, I always appreciate your comments. Thank you.

  • @lindaluzponcerosas4100
    @lindaluzponcerosas4100 3 роки тому +2

    I cannot life without your videos.

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      Linda, You are too kind. Appreciate the comment.

  • @Misschilaka
    @Misschilaka 3 роки тому +3

    your videos have been very helpful to my life. Especially biostatistics!! Thank you so much!

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому +1

      Victoria, Thank you for the kind words. I am glad videos have been helpful.

  • @nidiasarmiento6805
    @nidiasarmiento6805 3 роки тому +1

    Hi Dr Randy, thank you for your videos I really understand everything.

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      Nidia, Glad videos have been helpful.

  • @nalis074
    @nalis074 3 роки тому +1

    Hello Dr. Randy! love your videos! really appreciate your side comments about any topics which is basically integration . such what you normally monitor in pt who are given Amiodarone. you check for TSH lvl. That is great integration specially for someone who is gearing up for step in few weeks! really appreciate your videos! THANK YOU!

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому +1

      Nadib, Thank you for leaving such a thoughtful comment. Stay Focused, Finish STRONG!! Crush the exam.

  • @mishalshahab4913
    @mishalshahab4913 4 роки тому +1

    Huge respect for u Dr.Neil

  • @ifteeable
    @ifteeable 3 роки тому +1

    Thank you very much for your videos - very helpful indeed!

  • @saintsam7397
    @saintsam7397 3 роки тому +3

    Lost on 2D6 part of this video, hopefully the next videos will help with it. will appreciate it if someone can elaborate.
    I'm watching this series as the first thing for General pharm, I love your videos and love how they stick in my brain, more so than BNB so I thought of watching your series before any other source, ill just build up on this knowledge.
    THANK YOU Dr, Randy! you are a God sent.

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому +1

      Glad it was helpful.... I'll see if I can come up with something to discuss the 2D6, 1A2 etc...

  • @madzzzz3189
    @madzzzz3189 Рік тому +2

    For the 1st time I actually understood pharmacokinetics! 😅 thank you so much for these videos!
    this is the 1st time I'm watching your series and they are amazing! subscribed! 🙌

    • @RandyNeilMD
      @RandyNeilMD  Рік тому +1

      Thank you Madz... I appreciate you being a subscriber!

  • @harvey2733
    @harvey2733 3 роки тому +1

    thank u so much dr. randy. u r a savior

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      Suraj, Making me feel like Maximus... Savior... good for my ego. Thank you.

  • @hiiii4854
    @hiiii4854 9 днів тому +1

    Thank you so much

  • @Michelle-fn5nc
    @Michelle-fn5nc 4 роки тому +1

    great timing! I was reviewing this today :)

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому +1

      Michelle, Hope it was helpful. Thank you for commenting.

    • @Michelle-fn5nc
      @Michelle-fn5nc 4 роки тому

      Randy Neil, MD it was really helpful! Thank you so much for your effort in making these !

  • @mehv58
    @mehv58 2 роки тому +1

    This was so helpful! thanks!

  • @ewertonuchoaMD
    @ewertonuchoaMD 3 роки тому +1

    Amazing!

  • @xaaboopinkly
    @xaaboopinkly 3 роки тому +1

    Thanks sir for your efforts! Appreciated !

  • @perseveranceinprincess
    @perseveranceinprincess 4 роки тому

    Thank you for this lecture ,solved my difficulty in learning these topics!

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому

      Krupa, Glad it has been helpful.

  • @afghanbatmanspidermanalija7593

    Thank you so much sir for your nice lectures, it is more beneficial

  • @SherieshAggarwal09
    @SherieshAggarwal09 3 роки тому +1

    U r a saviour...❤️

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      Sheriesh, You are welcome. Thanks for commenting.

  • @rachaelias7636
    @rachaelias7636 Рік тому

    Amazing video

  • @user-cf1if7ff3h
    @user-cf1if7ff3h 6 місяців тому +2

    Thank you very much
    No word to sayb

  • @binoyphilips
    @binoyphilips 3 роки тому +2

    Love the videos. Please can we have the notes. Pharmacology makes so much sense now.

    • @muz755
      @muz755 2 роки тому

      hey, did u get the notes by any chance?

  • @olgabockeria6940
    @olgabockeria6940 3 роки тому

    perfect lessons! all of them! Please upload your notes for downloading

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      Thank you for commenting. I'm working on correcting the downloads

  • @aluken2003
    @aluken2003 Рік тому

    Thanks again.

  • @Sam_1964
    @Sam_1964 2 роки тому

    Outstanding teacher

  • @aloksah513
    @aloksah513 4 роки тому +2

    Thank you very much dr. for such wonderful questions & concepts.
    plz make video on pharmacodynamic 🍃

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому +1

      Alok, Thank you for the comment... I will eventually make my way to the DYNAMICS

    • @aloksah513
      @aloksah513 4 роки тому

      @@RandyNeilMD 😊👌👌

  • @usmleislife3396
    @usmleislife3396 4 роки тому +1

    Aswm...👍🏼👍🏼

  • @aroojaadil5667
    @aroojaadil5667 3 роки тому +1

    Ur awsum dr neil

  • @starmadu9343
    @starmadu9343 3 роки тому

    You atr a life saver

  • @jyotidave488
    @jyotidave488 Рік тому

    🎉🎉🎉

  • @MBBSZaraHutKay
    @MBBSZaraHutKay 2 роки тому +1

    Love ❤️ ....

  • @sambrummer5158
    @sambrummer5158 Рік тому

    Hi Dr Neil, I was looking for a link for the notes page but have not been able to find it. Are the notes for the pharm videos available?

  • @annauy6577
    @annauy6577 Рік тому

    Thank you for your very informative videos. I’ll definitely share these to my friends. May I ask where I can get your notes?

  • @lindamartin2764
    @lindamartin2764 3 роки тому +1

    THANK U

  • @monaelj2628
    @monaelj2628 Рік тому

    Hi Dr Randy , thanks so much for your help, just one question please where can i find your notes at 18:38

  • @Rakeshpandit-pr4qr
    @Rakeshpandit-pr4qr 3 роки тому

    Dr Randey your video is reallly helpful.But I want to point out that quinidine is potent enzyme inhibitor not inducer so plz correct it.Anyway plz do not hurdle here continue adding more video like this. I wait for it.

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      I think I had mentioned that it changed from step1 Books... I believe I had mentioned it in the video... but I said the pneumonic I learned had it the old way.

  • @aluken2003
    @aluken2003 Рік тому

    Thanks Dr Randy for the amazing helpful videos on Pharmacology. Is there a way I can get/purchase your pharmacology notes ? I do not see them on your website. Thanks

  • @ParthPatel-so9ec
    @ParthPatel-so9ec 4 роки тому +6

    Hi Dr Randy , i would like to point out that Azithromycin is exception among macrolide as it doesn't affect Cyt P450 activity so is safe to use in patient on warfarin.

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому +2

      Thank you for the accuracy. I didn't check that. I just gave examples about drugs in category... THANK YOU

  • @_dr.abhi_
    @_dr.abhi_ 3 роки тому

    thank you somuch... I found pharm very ery difficult but not now ...

  • @yishwererkaradapanddy3378
    @yishwererkaradapanddy3378 3 роки тому

    I can't find the pharmacology pdf on the website. Where is it?

  • @francescarestea4772
    @francescarestea4772 2 роки тому

    Does anyone have his Notes pdf on Pharmacokinetics, please? I looked on his website and I only found the BioStats. Thank you!!!!!!

  • @anndrerivas
    @anndrerivas 3 роки тому

    Thanks Dr. Neil! so helpful! is there any place where I can find the sheet? Thank you so much

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому +1

      Andrea, Eventually I will have them on my website. It may take some time bu they will be there...

  • @randomone3858
    @randomone3858 3 роки тому +1

    Sir plzz do more videos of basics stuff like behaviour, communication skills , genetics , virology

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому +1

      I will definitely make more videos... Thank you for commenting...

    • @randomone3858
      @randomone3858 3 роки тому

      Thanks alot

  • @mohammedabdulkadir5250
    @mohammedabdulkadir5250 4 роки тому

    Doctor, i like black/white color..cool

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому +2

      Mohammed, Thank you for the feedback. The simpler technology, the less distraction...

    • @mohammedabdulkadir5250
      @mohammedabdulkadir5250 4 роки тому

      @@RandyNeilMD well said doctor.

  • @ArunKumar-tc9ky
    @ArunKumar-tc9ky 4 роки тому

    Sir!. The video was helpful. Can you mention the mnemonic for cyp inducers and inhibitors in the description. Thank you

    • @ParthPatel-so9ec
      @ParthPatel-so9ec 4 роки тому +1

      CRAP Mobile GPS induces my rage
      Carbamazepine , Cyclophosphamide , Rifampin , Alcohol , Phenobarbital , Modafinil , Griseofulvin , Phenytoin , St. Johns warts and Sulfonylurea
      Inhibitors - by ruling out inducer choices
      Credits to Dirty Medicine
      I hope it helps 😊

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому

      Appreciate you sharing... Thank you.

  • @1DOLLARS1828
    @1DOLLARS1828 3 роки тому +1

    thank you again. Just wondering if you are tutoring. like giving one to one class?

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому +1

      Abali, Thank you for the vote of confidence, but I'm not sure I know much more than what I give you on the videos... I enjoy teaching and miss it... so at least we have the UA-cam forum...

  • @nihaarshrestha
    @nihaarshrestha 4 роки тому +1

    Dr Neil Can you please share the handsout.. thank you for your videos 🙏🏼

    • @RandyNeilMD
      @RandyNeilMD  4 роки тому +1

      As soon as I can have them uploaded...yes.

    • @nihaarshrestha
      @nihaarshrestha 4 роки тому

      Randy Neil, MD Thank you from the bottom of my heart.. 🙂

  • @samia9563
    @samia9563 3 роки тому

    can you share whats written about cyp2D and else.? either my screen is not sufficient or paper is quite blur

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому +1

      I will share. Trying to put everything in PDF format and then on webpage first.

  • @amrutajoshi7058
    @amrutajoshi7058 3 роки тому +2

    where can we get the notes?? can someone please share the link?

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      Amruta, Should be online.. coastalmdlive.com

    • @sumeyye8674
      @sumeyye8674 2 роки тому

      @@RandyNeilMD Hi Dr. Randy, First and foremost, I love your videos! I couldn't find your pharma notes on that link. Where can I find it? Thank you!

  • @masaral-mashkoor9611
    @masaral-mashkoor9611 2 роки тому

    Hi dr randy
    From where can i get ur notes ?

  • @draftabmashooque
    @draftabmashooque 9 місяців тому

    From where I can get these notes...anyone please?

  • @mmaheadquarter9740
    @mmaheadquarter9740 3 роки тому

    all of us:67yrs old
    randy: a 76 yrs old patient...

  • @afagsafarova6734
    @afagsafarova6734 3 роки тому

    I really love your videos! very helpful. Dr. Randy can I write a question from my NBME that I got wrong and still did not figure it out? It is pharm question

    • @RandyNeilMD
      @RandyNeilMD  3 роки тому

      Of course... can't guarantee I'll know the answer but can try...

    • @afagsafarova6734
      @afagsafarova6734 3 роки тому

      @@RandyNeilMD
      women is given 500 mg of drug X. several min later her serum concentration is 12.5 mg/L. two hours later her serum drug X is 10 mg. Drug X has first order elimination, what would be her serum drug X in another 2 hours?
      A. 7.5
      B. 8
      C. 7
      D. 6.5

    • @kavyag4024
      @kavyag4024 2 роки тому

      @@afagsafarova6734 7.5?

  • @robertohidalgo782
    @robertohidalgo782 Рік тому

    Could you Upload your Pharm Notes to your Webpage

  • @emperormouse5487
    @emperormouse5487 Рік тому

    Pro Surfer Rider Macro Amy Goes Keto: Mnemonic for the inhibitors

  • @abduldanish6112
    @abduldanish6112 3 роки тому

    Hi dr, macrolides are inhibitors, except erythromycin, acc to uworld.

  • @mukta81
    @mukta81 2 роки тому +1

    Ok, now they are saying quinidine is an inhibitor

    • @RandyNeilMD
      @RandyNeilMD  2 роки тому +1

      luckily...they tend not to use the ones that fall in both categories ...but I could be wrong.

  • @zv8381
    @zv8381 Рік тому

    Half life was great example