How effective is NAD and its precursors for longevity?

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  • Опубліковано 20 січ 2025

КОМЕНТАРІ • 65

  • @gabymalembe
    @gabymalembe Місяць тому +6

    Anecdotal but I’ve been taking NR since 2018 as Resveracel. I’m 81, nothing hurts, ride my bike every day, feel good. No way to know if the NR is a contrbuter.

  • @ThomasNorthener
    @ThomasNorthener 8 місяців тому +13

    I'd like to know the opinion on GlyNac, rather then NAD

  • @mattstanbridge
    @mattstanbridge 8 місяців тому +14

    I've been taking it for 5 years. What benefits have I gained from it? It's hard to know what the 'me' without it would be like. All I can say is what I'm capable of and my appearance. I'm 55, people assume I'm about 15 years younger, I'm still very agile, very strong, and even though I've lost speed, I'm still fast. As well as going to the gym, I skateboard several times a week. Some of that may be down to genes or simply never allowing myself to grow old or even consider I'm ageing, basically maintaining a young mindset. The only hard evidence I have is when I used to play football ⚽️, I would need some good pre season training to start the season being able to do, according to my tracker, 40 or so flatout sprints, general jogging and some walking for 90 minutes a game. Covering around 8 km a game. The last season I played before, I decided to retire and just skateboard, I did no pre season training, but my first game it felt like I was 2 months into the season, I was running around and sprinting effortlessly, it was weird, and the only difference was nmn. Other than that, I can skate non-stop for 2 hours, probably more, without getting tired, I'm ready for breakfast after a couple of hours, though.

    • @bradlong7166
      @bradlong7166 5 місяців тому

      What dosage are you taking? And are you injecting it?

    • @mattstanbridge
      @mattstanbridge 5 місяців тому

      @@bradlong7166 About a gram under the tongue.

    • @hawakarshe7904
      @hawakarshe7904 24 дні тому +1

      Wow thanks for sharing

  • @rtypepe
    @rtypepe 8 місяців тому +22

    NMN has made a differance for me..... I am almost 60 years old and will continue. Also taking it with TMG

    • @liutasx
      @liutasx 8 місяців тому +1

      NMD doesn't help, you have wishful thinking

    • @sn0wfir3_
      @sn0wfir3_ 8 місяців тому

      And TMG only helps for working out

    • @pauln8503
      @pauln8503 7 місяців тому +3

      This is why it’s the most re-ordered supplement in the world- it works

    • @Just4AZ1
      @Just4AZ1 6 місяців тому +2

      At 70, I believe it makes a difference, but I live a healthy lifestyle in general so it is difficult to judge to what degree. Unless proven otherwise, and so far neither side is overwhelmingly convincing, I will continue using it.

    • @donovanumbra9704
      @donovanumbra9704 Місяць тому +1

      Yeah, I think a lot of these so-called experts are paid gatekeepers for the current pharmaceutical establishment. Notice how much he emphasizes current standard practices, which are often recommended because of the stents drug companies have. I think we need to take these talking heads with several grains of salt and give more weight to our personal powers of perception. 0:17

  • @TheBriarCottage
    @TheBriarCottage 8 місяців тому +9

    Dr. Attia, I would like your opinion on red light therapy.

    • @RodrigoPariente
      @RodrigoPariente 8 місяців тому +2

      He would get mad and say, are you doing 45 minutes of ejercice every day???

  • @2thdoctom
    @2thdoctom 8 місяців тому +2

    I have NMN powder from Renue. Figured I’d play human chemistry set with it and look for a single (self) case outcome. Wondering about bioavailability after 2nd pass metabolism. Too bitter for sublingual (and too much powder). Ruins coffee, and heat may denature the compound. So, I bought some cellulose capsules and filled them with the powder (2 caps/500mg). Renue instructions suggest 500mg BID. Is that an appropriate dose according to most recent data?

    • @theancientsancients1769
      @theancientsancients1769 8 місяців тому

      I wouldn't put it in a hot drink . Start at 500mg and see how you get on before increasing to 1000mg . Different people use the dosage they tolerate . But you must take TMG with for it to work

  • @nilforteza9154
    @nilforteza9154 День тому

    And... what about NMNH? No one talks about it

  • @Successfulmindsae
    @Successfulmindsae 2 місяці тому

    Id love a conversation arpund NAD and log distance runnibg or exercise. Im a ultra distance runner and I have to say since Ive been taking it I feel better, perform better and recover better. I use it for that more than any other benefits its has.

  • @judesterification
    @judesterification 8 місяців тому

    Would a severe niacin deficiency, like having pellagra cause someone to have very fragile, weak and thin connective tissue. Like ligament and tendon?

  • @marwanhagar7196
    @marwanhagar7196 8 місяців тому +4

    There's good data to support the use of NMN for endurance training, it has been shown to significantly improve cardiopulmonary metrics in several trials (within a short time period, appears to have a cute ergogenic effects like a pre-workout). With this knowledge, I think NMN should be taken in proximity to is cardiovascular exercise to get the most benefits from this ingredient.

    • @robynhope219
      @robynhope219 3 місяці тому

      Only the rich can afford NMN...NR is a bit cheaper🙁

  • @darthsoulglow321
    @darthsoulglow321 6 місяців тому +6

    Getting more nad and nmn is a great thing. So the fda bans it because of pharma!

  • @Cathal-unregressing
    @Cathal-unregressing 6 місяців тому +13

    You talked a lot without much direction

  • @junu0507
    @junu0507 8 місяців тому +6

    Lifespan probably not, but healthspan-wise, why not?

    • @miketermaaten26
      @miketermaaten26 5 місяців тому

      because it can push you into pre diabetes if taken in too large a dosage

  • @bretpark4485
    @bretpark4485 4 місяці тому +2

    I have the highest respect for Dr. Attia, but I'm afraid the topic of NAD precursor should be left to the experts who've seen the before and after benefits first hand -- especially with respect neuropathic diseases like Parkinsons, where either it works or it doesn't -- with little ground for placebo effect.

    • @meltedsnowman9637
      @meltedsnowman9637 Місяць тому +1

      That’s anecdotal evidence which is the lowest form of evidence on the scientific evidence hierarchy.

    • @bretpark4485
      @bretpark4485 Місяць тому

      @@meltedsnowman9637 Yes, tell that to all the users that swear by the "anecdotal" evidence. Having been involved in clinical trials for a living, I can honestly state that for many the evidence that truly matter are empirical in nature, especially as no supplement company can spend millions on trials or marketing.

    • @meltedsnowman9637
      @meltedsnowman9637 Місяць тому

      @@bretpark4485 I mean people historically swore by the anecdotal evidence of bloodletting. Doesn’t mean it was actually effective.

    • @bretpark4485
      @bretpark4485 Місяць тому

      @@meltedsnowman9637 Please don't confuse a primitive treatment forced on the unsuspecting before modern science with NAD precursor needed for over 500 enzymatic functions in the human body.

  • @juanpontif7577
    @juanpontif7577 12 днів тому

    There are studies showing it works in tissues outside the liver. I wish someone would challenge him .

  • @karenmcmillan4626
    @karenmcmillan4626 4 місяці тому +2

    Testing for longevity and wellness on patients with “death sentence” syndromes like ALS and Parkinsons makes zero sense. You need a large group long term age-related study of both men and women starting at age 40 -50 and following them for 20 -30 years. Start with a baseline full bloodwork and full mobility and strength testing for each participant. Then follow up testing each year. Otherwise I’ll take the information I’ve gotten from other participants in other studies. I’ve started taking Liposomal NMN+. I will see how it works for myself.

    • @Chares-ym8gw
      @Chares-ym8gw 19 днів тому

      Please kindly update me about your health experience with lipsomal NAD+ as I too will purchase it as well.

  • @Ryan-wx1bi
    @Ryan-wx1bi 8 місяців тому +18

    Tried it, gave me a headache every time. No thanks. People lived to 100+ without it. Ill just stick to a clean diet and lifestyle

    • @Jason5818UI
      @Jason5818UI 6 місяців тому

      Detoxification too..proper supplementation...the body aging because of DNA breaking..the environment..population etc. humans have existed long before western medicine

    • @7TheWhiteWolf
      @7TheWhiteWolf 6 місяців тому +1

      It gave me overwhelming energy and anxiety, heart palpitations and insomnia.

    • @joeschnur4632
      @joeschnur4632 3 місяці тому

      Did you measure your NAD levels before and during?

    • @marialiliaromero6930
      @marialiliaromero6930 2 місяці тому

      @@7TheWhiteWolf same!

    • @Iceman-xe7jo
      @Iceman-xe7jo 2 місяці тому

      If you live to be 100 plus I’m certain you’re a genetic anomaly.

  • @Jimmy-Legs
    @Jimmy-Legs 3 місяці тому +4

    Remember, this is the same guy who shills for AG1.

    • @robynhope219
      @robynhope219 3 місяці тому

      ??

    • @Jimmy-Legs
      @Jimmy-Legs 3 місяці тому

      @@robynhope219 He’s getting paid to shill for AG1. The $80 a month green vitamin drink.

    • @streetghost
      @streetghost 3 місяці тому

      ​@@robynhope219Look into the CEO of AG1 and his history of business practices. AG1 promoters are given a share of the company rather than a payout per ad. There is much financial incentive​ for people like Dr. Attia to promote a product with zero health benefits. It's a shame because it does make one question his other work that could actually be credible. Huberman, Joe Rogan and Chris Williamson are all promoting AG1 also...

    • @streetghost
      @streetghost 3 місяці тому

      ​@@robynhope219Look into the CEO of AG1 and his history of business practices. AG1 promoters are given a share of the company rather than a payout per ad. There is much financial incentive​ for people like Dr. Attia to promote a product with zero health benefits. It's a shame because it does make one question his other work that could actually be credible. Huberman, Joe Rogan and Chris Williamson are all promoting AG1 also...

    • @paulhailey2537
      @paulhailey2537 Місяць тому

      That's a great product , maybe you should use it

  • @dtanner215
    @dtanner215 5 місяців тому

    Take it subq small dose two or three times a week. You will feel 22 again. No benefits if you are actually young.

  • @wabash1975
    @wabash1975 2 місяці тому +1

    You infact CAN take NAD orally.

    • @KateAwakening
      @KateAwakening Місяць тому +3

      Yes, you can but it does not penetrate cell wall. It will do nothing for you

    • @debbiecato2101
      @debbiecato2101 21 день тому

      You take the precursors that maje your body create it . Sounds similar to glutathione to me

  • @whatthefunction9140
    @whatthefunction9140 8 місяців тому +2

    Als is proof there is no god.

    • @pr1ce213
      @pr1ce213 8 місяців тому +4

      Okay lol

    • @tommydinob
      @tommydinob 8 місяців тому +4

      Nonsense. But, obviously this place is a work in progress.

    • @TV-ob1if
      @TV-ob1if 3 місяці тому +1

      the earth and the scientific impossibility that this world and universe was created randomly proves there is a God

    • @Zephan-y2w
      @Zephan-y2w 2 місяці тому

      How is it proof Mr atheist

  • @irenekuznet847
    @irenekuznet847 8 місяців тому +3

    Aging "anti-aging " "doctor" tells us what to take. Nothing is more pathetic than...