Unmet needs in front-line therapy for patients with FLT3-mutated AML

Amir Fathi, MD, MPH, Massachusetts General Hospital, Boston, MA, discusses the unmet needs in front-line therapies for patients with FLT3-mutated acute myeloid leukemia (AML). Key areas for improvement include increasing remission rates and facilitating transplants for younger patients. For older patients, the standard treatments-azacitidine or decitabine plus venetoclax-are less effective against FLT3-mutated AML, making remission more challenging to achieve. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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