Memory and the Hippocampus
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- Опубліковано 6 чер 2024
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This neuroscience video will help you to understand the structures/anatomy and the functions of the hippocampus located within the medial temporal lobe of the limbic system. The trisynaptic circuity is the pathway of memory transmission in the hippocampus which is explained in the video.
The hippocampus is part of the hippocampal formation which includes the dentate gyrus, parahippocampal gyrus, and hippocampal gyrus. The hippocampal gyrus contains areas such as the entorhinal cortex and subiculum, which are both vital in the flow of information through the hippocampus.
The hippocampus is divided into CA1 to CA4 regions which stands for cornu ammonis. This is the area of the brain which has a very important role in memory due to the high levels of NMDA glutamatergic receptors located in the CA1 Schaffer collateral neurons. The synaptic plasticity of these neurons heavily relies on long-term potentiation (LTP) induction to allow the strengthening of declarative memory (which includes two types of implicit memory such as episodic and semantic memory - Facts and events).
The trisynaptic circuit receives sensory input from the cortical regions of the brain which enters via the entorhinal cortex. This projects via the perforant pathway to the dentate gyrus, then to the CA3 region via the mossy fiber pathway to future travel to the CA3 neurons through the Schaffer collateral pathway. Finally, this signal is outputted from the subiculum to the rest of the various areas of the brain such as the Fornix (which can loop back to the entorhinal cortex).
If the sensory input is very strong and is repeated multiple times, LTP will be induced to increase synaptic connections. This allows the trisynaptic system to occur more rapidly next time.
#Memoryformation #neuroanatomy #youcanlearnanything
What is the hippocampus? What does the Hippocampus do? Where does Memory and Learning occur in the brain? What is the hippocampus structure? Where is the hippocampus located? What is the function of the hippocampus? What does the hippocampus mean? How does your memory work?
We will answer all this in this video so let us know how we do!
Copyright Mentions:
• Footage Provided By a href="www.videezy.com" Videezy /a, www. videvo.net
• Xu, X., Sun, Y., Holmes, T. and López, A., 2016. Noncanonical connections between the subiculum and hippocampal CA1. Journal of Comparative Neurology, 524(17), pp.3666-3673.
• Henry Gray (1918) Anatomy of the Human Body Book
• Medical Dictionary 2011. Hippocampus (Online). Available: medicine.academic.ru/3923/Hip... (Accessed 31 March 2020).
• Hippocampal Neurons Image by Dr. Wutian Wu Affiliatio: CTO, Re-Stem Biotechnology, Suzhou, China -nikonsmallworld
• Basal Ganglia In The Brain from Science Photo Library Art - Pixels.com
• Freestyle Beat from www.MixlaProduction.com - Наука та технологія
sweet !! That is really cool love the breakdown of the hippocampus index , 🔥🔥🔥🔥,
Love it coincidence receptor, haha!!
So what's is the most effective way to strengthen the hippocampal neurons for a specific episodic memories?
Apart from repetition which is 💤💤 ?
Thanks, I am glad you enjoyed the video! @chanel Tink Gave provided an excellent explanation! I hope that answers your question. What you will find out in our next video also is the key role of dopamine in Long-term potentiation. Dopamine is the reward signal for memories being novel and exciting. It acts as a memory modulator, therefore, helping you to remember things if the thing you are learning is new and exciting. This is why I would assume strong episodic memories are formed since you can't really practice repetition with eventful memories (thus relying on novelty to initiate LTP). Especially because most events when you remember them for the second time you actually change the memory to the last time you remembered it. This was actually really interesting and I recommend you search it up!
Interesting, if I do a moderate workout after studying I can consolidate better I like that, I can do moderate rehab circuits after studying I test it out !! #selfappointtedguineapig
@@chaneltink6071 this is very helpful cheers !!
@@BioBrainBuddies thank you for your reply, brain requires creativity to excite it seems to bring the best out of it, it would be great to have a way of learn that mimicks the level of dopamine in the body when your remembering repetetitive tasks!!! Or event, but yes will look into it appreciate it
Yeh definitely! Hope that help!
Well, when you are an engineer and this is your hobby, it's getting kinda complicated because my base is almost non-existent
Wonderful work Chanel as always!! Reading looking forward to seeing more of your videos!
Thank you!
simple yet finely structured narration, beautiful voice (!), and simple easy to follow animations and schemes. thank you so much for this and ur last video(LTP) :DD
Thank you so much for your comment! Means so much, I am so glad you enjoyed both our videos on memory!
Super insightful! Took me back to when I studied psychology. The brain is a powerful thing! 🔥 when’s the next episode?
Thanks for watching! as Chanel said yeh around a month or two untill the next video!
Concise and easy to follow! Awesome stuff :)
Thanks Andrada! :) :) :) :)
Great job explaining ~ Thank you!!!
Thank you for watching !
my wife was diagnosed with Alzheimer's in 2010 at age 59 and is still living in nursing home, mute, completely unaware of her surroundings and immobile bed-bound.... but she can swallow and manage her airway, has to be spoon fed by caregivers and but maintains basic homeostasis. in 2010 her csf showed the expected elevated tau and low amyloid, her MR was diagnostic for "marked hypoperfusion in the frontoparietal and posterior cingulate gyri".
they call it the long good-bye, yes very very long in an otherwise totally healthy non-smoker as she was.
I am sorry to hear that :(
Your wonderful work is highly appreciated , Thanks
Thank you glad you enjoyed! Need to get back to making more at some point!
I loved this! THANK YOU!!!
Thank you so much!
Very helpful and informative!
Thank you Margarita!
Thank you. This is great. Is there a video thst can show how to activate and stimulate this part of the brain.
And show how the memory differs in the Hippocampus compared the Basal Ganglia.
Thank you! May your channel grow with such great content
Thank you for watching! Interesting thought yeh I can definitely look into it for our next video. It's been a while as we have been quite busy with other things but more videos will come soon!
Me encanta. ¡Espero su siguiente vídeo sobre potenciación a largo plazo! Saludos desde Perú
Thank you so much for watching!
Neat. I am having my hippocampus laser ablated next week and I am so scared about what my memory will function like/or not function like after surgery. I am making videos to share the process if anyone is interested personally...
Wow I hope that goes all good! I'm sure you will get through this, my thoughts are with you! Thanks for sharing will check out your page x
keep creating videos, you explain very well
Thank you so much! I do need to create some new videos soon!
4:11 Nice hippocampal beatbox at the end!
Thank you yes thought that would be a special touch!
@@BioBrainBuddies My Hip-hopcampus appreciates the beat input!
@@psychedelictacos9118 Hahah no worries :)
@@psychedelictacos9118 🤣
Great video, great narrative. Lovely voice
Thank you so much! It means alot to us!
Very usefull video about hpcmps. Insightfull and attractive
Thanks for watching!
Brilliant, thank youu!
Love your voice btw
Thank you for watching! It means alot!
Thank you ! You have a lovely voice :D
Thank you! Glad you enjoyed the video
PLease do more videos!
We really want to continue doing videos! At the moment both of us are quite busy pursing our careers so its been quite hard to keep making videos but its still a passion of our to keep building up this channel just is taking some time!
wow this was very informative!! i dint knew my brain is carrying so much stuff 😅 and especially i dint knew that the word hippocampus came from seahorse 😲.
excellent work with the graphics and voice 👏🏻👏🏻
can't wait for the next one😁
Thank you so much for the feedback and for watching the video! It means alot to us :)
I love the presentation
Thank you so much!
Great to watch.....first time through this video I came to known about the full form of CA neuronal cell bodies.....i also tried to make one tutorial session on memery & neuroplasticity....in my channel... 🙏
i love this video thanks for a nice video
Thank you x
Easy to follow
Thanks for watching#
Thank you :)
Great video.
Glad you enjoyed it!
Thanks from Brazil
Thanks for watching our content!
Ma'am, can physical pain tolerance and mental pain tolerance give psychological strength and power?
Just wow ❤❤❤
Thank you
Subscribed.... 👍
Thank you! 😄
thnx buddy 🔥
No worries :)
cool!!
Thanks!!!
ECCEZIONALE
How to improve hypocampus function?
Hey, Thanks for watching! One latest research I have read is that intermittent fasting has been shown to increase the Neurogenesis of hippocampal neurons. This seems to happen as when in fasted fast the body needs to use its resources to hunt and be alter and remember things better instead of just relaxing.
Hope that helps! If you like the video please subscribe and share the video! We are a up and coming channel and it would help us out alot
Why, of all things, did you choose playing the piano as an exemplar of an episodic memory? This is a fine example of a basal ganglia-mediated skill, which interestingly is well preserved in Clive Waring, who is densely amnestic due to hippocampal damage arising from herpes encephalitis. .
Piano playing was an example was procedural memory not episodic. It is a main example because of the case study on HM showed he was still able to play the piano even after the removal of the hippocampus.
Can I increase my hippocampus size and its function?
I am not sure there are many studies suggesting increasing hippocampus size. There is one paper I just found from 2011 which suggest physical exercise helped increase by 2% and helps maintain size and function during late adulthood when otherwise the functions decrese slightly.
Hope that helps
Nice❤
Thank you!
ah yes the hyppocampus or shrimp inside our brains
the good old brain shrimp
Great video guys! I am looking for guests in my podcast series, especially neuroscience. If you want to be part in it, feel free to reach out :)
Hey thanks for watching! Thanks for the invite I will discuses it with my team and consider it as an option to do in the future for our channel!
This is sick I love her
Thank you!
fragments of self...
Pls wach this its imsame
Thank you!
@@BioBrainBuddies you should really be good at aience now
Haha thanks we try are best 😅
@@BioBrainBuddies your really good well don
@@mrreconsweat1678 Thanks Kai!
Hrllllllloooo
Hello :)
Can you live without a hippocampus? 😂
Yeh you just won't be able to remember new things like the case study HM who could remember things that he learnt before but can't form new memories after his hippocampus was removed