Renin Angiotensin Aldosterone System | RAAS Part 2👨⚕️
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- Опубліковано 2 сер 2024
- #drnajeeb #medicines #pharmacology #medicaleducation #renin #drnajeeblectures
Renin Angiotensin Aldosterone System | RAAS Part 2👨⚕️
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▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬
00:00:00 Polkissen cells, Lacis cells & Macula Densa cells
00:02:47 Juxtaglomerular Apparatus
00:04:03 Release and basic functions of Renin
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The renin-angiotensin-aldosterone system (RAAS) is a critical regulator of blood volume, electrolyte balance, and systemic vascular resistance. While the baroreceptor reflex responds short term to decreased arterial pressure, the RAAS is responsible for acute and chronic alterations.
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Most of the Sodium is reabsorbed in the kidney tubules.
There are Sodium sensing cells called as macula densa lining the tubule at the junction of DCT and thick Loop of Henle.
Special muscle cells ling the afferent arteriole is called Juxtaglomerular Granular Cells. These cells lie between macula densa and Polkissen cells
Together, the Polkissen cells, JG cells and macula densa constitute JG(Juxtaglomerular apparatus).They produce Renin.
When there is blood loss, renal perfusion is less. And movement of fluid through the tubule is slow. So there is more Sodium is absorbed. So less sodium comes to macula densa. Macula densa produces NO which activates JG cells and JG cells produce major proportion of renin.
Whenever Blood pressure falls down, like during blood loss, carotid sinus signals CNS
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think ive taken more notes watching your first two videos on RAS system then I have in the first 5 weeks of uni
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Thank you for this great explanation of the RAA system!
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I'm from mexico thanks alot teacher I'm gonna talk about renin angiotensin sistem
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Nice lecture..
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regards from romania
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very very thanks sir ji
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nic
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