What Is Dopamine And How it Works. Under 15-minutes.

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  • Опубліковано 3 січ 2023
  • In this video, I delve into dopamine - a vital neurotransmitter that plays a significant role in motivation, happiness, and overall brain function.
    Dopamine is known as the brain's "reward" chemical. It's responsible for feelings of achievement, pleasure, and excitement. Understanding dopamine can help you unlock your potential and improve motivation, enhance productivity, and experience increased happiness levels.
    I first cover the science of dopamine and dopaminergic pathways (including mesolimbic and mesocortical pathways). Then I'll explore high and low dopamine symptoms and signs. Then I discuss lifestyle practices scientifically proven to enhance dopamine production.
    This video is your comprehensive guide to dopamine, backed by scientific research.
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    Timestamps:
    00:35 What is Dopamine
    00:40 Where is dopamine made?
    01:18 How is dopamine made?
    01:49 Dopamine pathways and dopaminergic projections
    02:02 Mesocortical dopamine pathway
    02:52 Mesolimbic pathway
    03:55 Nigrostriatal pathway
    04:20 How is dopamine released and how does dopamine work
    06:25 Dopamine levels and COMT gene
    07:00 Lower baseline dopamine: val/val
    07:25 Higher baseline dopamine: met/met
    08:24 High dopamine symptoms
    09:15 Low dopamine symptoms
    10:02 How to increase dopamine
    11:45 How to lower dopamine
    12:13 Dopamine detox or dopamine fasting

КОМЕНТАРІ • 42

  • @whitenoises5264
    @whitenoises5264 4 місяці тому +1

    Tonic and static modes are excellent.

  • @iakona23
    @iakona23 Рік тому +4

    I really like the topics which you are choosing to address on your channel here. Superb! Thank you.

    • @iaminkaland
      @iaminkaland  Рік тому +1

      Thank You Good to hear :) lmk if you have wishes.

    • @iaminkaland
      @iaminkaland  Рік тому

      Thank You Good to hear :) lmk if you have wishes.

  • @SiimLand
    @SiimLand Рік тому +4

    Love it

  • @mailaimmonen5921
    @mailaimmonen5921 Рік тому +2

    Super intresting 🤓

  • @mohammedabdulkadir2004
    @mohammedabdulkadir2004 Рік тому +1

    great vedio !!! am from east africa ,ethiopia

    • @iaminkaland
      @iaminkaland  Рік тому

      Thanks, glad to hear you liked it. hi to ethiopia

    • @mohammedabdulkadir2004
      @mohammedabdulkadir2004 Рік тому

      @@iaminkaland ameseginalew my konjo in ahmaric language ,meaning in english thank u my beautiful

  • @homejonny9326
    @homejonny9326 2 місяці тому

    thanks for the video!
    this subject is fascinating 🎉😊

    • @iaminkaland
      @iaminkaland  24 дні тому

      Thanks for your comment. Yes, one of my favorite ones!

  • @ian-flanagan
    @ian-flanagan 4 місяці тому +1

    8:16 Do you know any widely available genetic tests that include VAL/VAL or MET/MET? Thanks for the video

  • @dimasokva8673
    @dimasokva8673 5 місяців тому

    Thats a good explanation, but how can low serotonin levels also create high dopamine levels? If low serotonin makes us less happy, it is normal for our dopamine to be low (loss of interest, etc) but why is low serotonin associated with high dopamine, is it just for some people or people in general?

  • @roselilly8847
    @roselilly8847 Рік тому +1

    Very helpful information. Does is connected with couldn’t stop eating ones you start eating after fasting? Thank you

    • @iaminkaland
      @iaminkaland  Рік тому +2

      Yes it can. Check out this video, it explains :) ua-cam.com/users/shortscP_kgbbiCVQ

    • @roselilly8847
      @roselilly8847 Рік тому +1

      Thank you!

  • @panagenesis2695
    @panagenesis2695 Рік тому +1

    I've heard supplemental l-glutamine can be good for gut health. Seeing as how the intestines can produce neurotransmitters, would supplementing glutamine improve dopamine levels?

    • @iaminkaland
      @iaminkaland  Рік тому +1

      Good question. I haven't found direct studies on this. But I'd think so. L-glutamine lowers inflammation and can improve the epithelium in the gut. And improving gut health and lowering inflammation would have positive effect on the normal production of gut metabolites and neurotransmitters. L-glutamine is a precursor for two pther neurotransmitters - glutamate and GABA and would probably have a bigger effect on those.

  • @muddimert
    @muddimert Рік тому +1

    Great Video, very informative. I have the COMT worrier gene, so have tried to support with Magnesium supplementation (glycinate), but even if I have a low dose (120mg) I get super anxious and feel terrible. Lol weird, because I thought it should do the opposite, so I’m wondering if Glycinate is affecting my MCAS. Anyway, thank you 😊

    • @iaminkaland
      @iaminkaland  Рік тому +1

      Thank you!
      Have you tried Magnesium complex that has different types of Magnesium? Or changing the form? For example, magnesium citrate is often used in studies where they've found anti-anxiety effects. Some studies use much higher doses as well - like 200-400 mg.

    • @muddimert
      @muddimert Рік тому

      @@iaminkaland many thanks for your reply, I will certainly look in to that as I appreciate how important magnesium is for one’s health. Have a great day 😊

  • @isabellascarlett807
    @isabellascarlett807 Рік тому +1

    Very very very good overview about about dopamine! Well done! 👍🏼 I‘m a psychiatrist myself and as far as I know, there can be high and low levels of dopamine in the brain at the same time, just in different areas of the brain (e.g. in schizophrenia). So regulating the dopamine is a very complex procedure. 😅 Do you know whether SSRIs influence the dopamine levels? Really appreciate your profounding videos! Thanks for your work! 🙏

    • @iaminkaland
      @iaminkaland  Рік тому +1

      Thank you for the comment 🙏 I am glad you liked it! 👍🏼 That's correct - You can have different levels and signals in different systems like low striatal D2 and high prefrontal D1. So yes, dopamine is complex. I tried to do justice to it as much as possible in a 15-minute video😅 This review suggests that SSRI lowers dopamine and it explains some of the negative side-effects of SSRI: pubmed.ncbi.nlm.nih.gov/15323590/

    • @isabellascarlett807
      @isabellascarlett807 Рік тому +1

      @@iaminkaland Thank you very much for the article. 🙌🏼 Very interesting! I very much appreciate your work! 👍🏼

  • @llsa2009
    @llsa2009 8 місяців тому +1

    Can dopamine be tested using a blood sample?

  • @Reet7482
    @Reet7482 2 місяці тому

    I have magnesium complex by bio emblem it has malate, Glycinate and citrate. Can I still take magnesium L threonate?

    • @iaminkaland
      @iaminkaland  Місяць тому +1

      Yes, you can :) just tweak the doses accordingly.

  • @alessandrofacciani7209
    @alessandrofacciani7209 Рік тому +1

    We are like cacti in the rain forest “Anna Lembke”.

    • @iaminkaland
      @iaminkaland  Рік тому +2

      Yes, I love this metaphor. We live in abundance.

  • @jeanpaulkassdale
    @jeanpaulkassdale Рік тому +1

    Does it mean that vegeterian animals have no dopamine ?

    • @iaminkaland
      @iaminkaland  Рік тому +2

      Tyrosine is also found in plant sources :)

    • @jeanpaulkassdale
      @jeanpaulkassdale Рік тому

      @@iaminkaland Nice, but does it mean carnivore and vegetarian species rely differently on dopamine ? You seem to suggest that dairy, meat and eggs contain more tyrosine than veggies so I assume carnivores get more of it ?

    • @jeanpaulkassdale
      @jeanpaulkassdale Рік тому +3

      @@iaminkaland Great video though, very explicative, simple, straight to the point, thanks !

    • @iaminkaland
      @iaminkaland  Рік тому +1

      ​@@jeanpaulkassdale Good question. Vegetarians eat dairy products, eggs, and soy which also contain tyrosine. I found a study that vegetarian plasma tyrosine was not significantly different than meat and fish-eaters. But vegans had lower tyrosine so possible they have lower brain dopamine as well. Vegan diet is also risk factor for other nutritional deficiencies which would affect neurotransmitter synthesis.
      pubmed.ncbi.nlm.nih.gov/26395436/
      www.sciencedirect.com/science/article/pii/S0261561420306567

    • @iaminkaland
      @iaminkaland  Рік тому +2

      @@jeanpaulkassdale Thank you! glad to hear it resonated.