How Does Fluoride Change Your Teeth?

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  • Опубліковано 25 тра 2020
  • Support the channel by joining our newsletter: bit.ly/watchclockwork
    Let's talk about how fluoride ions straight-up change the chemistry of your teeth.
    This video provides a solid introduction to this topic, but can't hit all the important details. Corrections, clarifications and sources are here: bit.ly/clockworkep2
    This channel is created with the support of all our patrons on Patreon: / clockworkshow
    Support the channel directly with a one time donation: www.paypal.me/clockworkshow
    This channel is dedicated to sparking your curiosity about biochemistry, not to being a definitive resource. To help you continue you biochem journey, I'm really excited to partner with Biocord , a Discord server dedicated to bringing together biologists from around the globe! Join the conversation with thousands of life sciences professionals and enthusiasts here:- / discord
    All music is by Jeremy Blake( / redmeansrecording , released on the UA-cam Audio Library.
    Intro music: Let's Go Home (bit.ly/rmrlgh)
    Outro music: Lost and Found (bit.ly/rmrlnf)
    The style of this video was largely developed based on tutorials by Ben Marriot: (bit.ly/posterizethis)
    Learn more about tooth formation and chemistry in my post on the subject here: bit.ly/clockworkep2

КОМЕНТАРІ • 123

  • @morganstock4660
    @morganstock4660 3 роки тому +113

    Have you considered that the acid sensitivity is as simple as the basicity of hydroxide vs the basicity of fluoride? going from pH 6 to pH 5, you'd see a 10x drop in hydroxide concentration, thus reducing the amount available to remineralize into hydroxapatite. fluoride, however, is a weak base and won't start to protonate until the pH drops below 4ish (given that the pKa of HF is around 3).

    • @Clockworkbio
      @Clockworkbio  3 роки тому +51

      Yea, what I learned from the feedback to this video is that I don't remember my pchem fundamentals NEARLY as well as I remember my biochem fundamentals. I bit off more than I could chew--completely forgot to mention pKa in this ENTIRE video, and instead of a real paper, my primary source was an article funded by a toothpaste company. Complete scripting disaster from back to front. This video is _close_ to accurate--but not close enough. However, I really like your comment because it summarizes the problems with my script really well. So, if you're cool with it--I'm pinning this comment.
      After this video I got a lot more fact checking support from my network, specifically my community over a the Biocord discord server. Maybe after I crack open my pchem textbook a few more times I'll dip back into videos like this--but definitely not for a while. There are enough proteins for me to write about without reaching too far into the fields I don't remember enough.

    • @trailblazer7702
      @trailblazer7702 2 роки тому +1

      Chemistry of aqueous solutions! :DDDDD

    • @matejvidovic7859
      @matejvidovic7859 2 роки тому +2

      Definitely the most detailed video on chemistry behind it on UA-cam. Does anyone have suggestions as to where one should look to read on scientific papers on this topic. I'm doing a research project on Le Chatelier, equilibrium, pH...I need chemical equations regarding products and reactants, acids and bases, conjugate acids and conjugate bases...does anyone have a link with detailed info on this?

    • @daviddimbleby6725
      @daviddimbleby6725 Рік тому

      Could you elaborate Morgan......

    • @BranTaliesyn
      @BranTaliesyn 5 місяців тому

      The 'glorious clockwork' eh'? I can even see how one eyed ,color blind, and dead the lens you look at this living universe is from the PowerPoint thing. I kant even rn, Humen. ✌

  • @drpaul-dentist
    @drpaul-dentist 17 днів тому +14

    I am a dentist and stumbled upon this post. Let me say that you did a wonderful job. Like one of the other correspondence, I too grabbed a toothbrush and brushed my teeth after viewing this post. You did ask for corrections and clarifications which is most commendable and thus I assume you follow scientific principles of getting things right. I ran this by a dental materials PhD. Here is his assessment of your explanation: "Apart from it being somewhat inaccurate, the topic is well presented. Fluoride has an anti-cavity effect, and the epidemiological evidence is good. However nobody knows precisely how or why it works. The solubility differences mentioned in the post is minute (x0.6). Fluoroapatite is not formed - CaF2 is. The solubility ratio is constant over a large pH range, and there is NO switch point: it is an artifact of bad data plotting and analysis. Do it right and the illusion vanishes. Tooth mineral is not Hydroxyapatite, but a biological apatite with many important differences. Remineralization is not actually true.
    The fact is, it is an embarrassment to the folks that work on fluoride that they cannot explain the exact mechanism.
    However we do know with great certainty that fluoride does reduce tooth decay and is safe in therapeutic doses."
    Please note that I offer this as a constructive critique. I highly regard the manner with which you attempt to explain difficult and complex biological concepts in an understandable fashion for the lay public. Keep up the good work.

  • @janeenduff1589
    @janeenduff1589 3 роки тому +64

    I am a retired dental hygiene educator. I am working on a presentation for nutrition students on oral health as it relates to cariology, dietary counseling and saliva testing. In preparation I've been viewing a lot of videos lately and THIS is short, to the point, simplified science and awesome for visual learners. Thank you so much!

    • @vaerner
      @vaerner Рік тому +1

      Indeed. I loved the way this video conveyed the importance of balance

  • @philp1232
    @philp1232 4 роки тому +29

    As a fellow biochemist, I love how you explain this stuff great job cant wait to see you make more!

  • @CKTCation
    @CKTCation 4 роки тому +14

    This was so fascinating and the animation is really beautiful. Amazing video - can't wait to see your next one!

  • @miccecca
    @miccecca 3 роки тому +26

    I’m glad you mention that over-fluoridated water can be toxic; while we know it to strengthen teeth, I‘d like to know more about what happens when it’s ingested.

    • @YahwehhasgivenaservanttoHis
      @YahwehhasgivenaservanttoHis 6 місяців тому

      3years on…
      Taking the “drug” prescribed by municipal water districts (do they have a license to practice medicine…!) systemically (internally) affects only your teeth and has no impact whatsoever on your soft tissues organs or any other part of your body…
      Trust me, I am a scientist.
      Butcher…

    • @DASLAKILL
      @DASLAKILL 13 днів тому

      It's a neurotoxin and an adjuvant for other heavy metals. Half the fluoride ingested stays in your body building up.

  • @Annapolisz
    @Annapolisz 2 роки тому +4

    Your modesty and sense of humor make this already fascinating video even more lovable.

  • @jesseyvanbeek3421
    @jesseyvanbeek3421 4 роки тому +8

    Amazing video, this explanation makes a lot of sense and I like the message in the end. Looking forward to your next video!

  • @flyingsquirrelproductions2373
    @flyingsquirrelproductions2373 3 роки тому +4

    Coming from a biochem grad student, this channel is awesome!! Keep up the great work!

  • @bryanalexisleoncastillo316
    @bryanalexisleoncastillo316 4 роки тому +4

    Gorgeous video, loved the final message

  • @javokhir1556
    @javokhir1556 2 роки тому +17

    Briefly about fluorine: the fluorine atom is small enough and has the highest electronegativity. As a result of the formation of bonds, the electron that took the fluorine is very close to the nucleus, and the screening effect is minimal. Therefore, it is much more difficult to expel fluorine from apatite than the hydroxyl group.

  • @kevinjiang6647
    @kevinjiang6647 4 роки тому +73

    here before this channel becomes the next kurzgesagt ;)

    • @bmw_m4255
      @bmw_m4255 Рік тому +6

      It didn't

    • @bintanglintangerlangga1983
      @bintanglintangerlangga1983 Рік тому +5

      He stop making video 2 year ago so sadly it will never be the next kurzgesagt
      Edit: He is making a season 2 it might aswell be the next kurzgesagt

    • @pizzainc.1465
      @pizzainc.1465 25 днів тому +2

      Kurzgesagt, or less commonly known but technically still valid, “in a nutshell,” does not deal with biochemistry. So they could coexist. Also he may have ran out of topics, at which point he would need suggestions

    • @savethestick8609
      @savethestick8609 24 дні тому

      @@bmw_m4255it will

    • @savethestick8609
      @savethestick8609 24 дні тому +1

      @@bintanglintangerlangga1983he’s making a season 2 as views have increased 🎉🎉🎉🎉

  • @svetlanacarver9020
    @svetlanacarver9020 3 роки тому +1

    Amazing! Thanks for this video. It’s so easy to understand and learn about the different parts of the body. Can’t wait for your next video!! xx

  • @djt7387
    @djt7387 6 місяців тому +1

    That was fun to listen to. Thank you for compounding knowledge.

  • @FrenkMelk
    @FrenkMelk Рік тому +4

    so the exact mechanism of fluoride in tooth Health has been kind of an imponderable for me. this morning I finally decided to look on some UA-cam videos for answers. I was very impressed with the angle you take and describing the processes and understanding that the limits of your personal knowledge are not bounded and open to review as well as editing from your peers. good job!

  • @green0563
    @green0563 3 роки тому +1

    Amazing. Subscribing a minute in, because this is just so good.

  • @LongLiveTheDoors67
    @LongLiveTheDoors67 2 роки тому +5

    This was a great video! I just got my first huge cavity a week ago--dentist appointment is next week--and so I've been on an education binge on what to do to help treat it. You are exactly right that most coverage of the effects of fluoride end at just saying "do it, it makes your teeth stronger". That infuriates me to no end! I wanted to know WHY it works, and your video did an excellent job of clearing it up. I truly appreciate the work you put in, I'll be subscribing for sure!

    • @safsult
      @safsult 8 місяців тому

      I recently learned about xylitol ,after every meal or drink ,use a xylitol gum ,balls or pearls

  • @grumpyuncle.
    @grumpyuncle. 5 місяців тому +1

    Excellent content! Well done!

  • @goldreserve
    @goldreserve 11 місяців тому +2

    Earned a sub, great video.

  • @user-jn4ms6dd4s
    @user-jn4ms6dd4s Рік тому +5

    I have a tooth that needs root canal and periodontal pockets. Every time I use fluoride toothpaste I get severe pain and inflammation, this doesn’t happen when using fluoride free toothpaste ever

    • @cosmolosys
      @cosmolosys 8 місяців тому

      maybe you are allergic?

    • @protosfotod2416
      @protosfotod2416 19 днів тому

      Use your brain and put 2 and 2 together. Or listen to your body.

  • @RasmusKramerSchou
    @RasmusKramerSchou Рік тому +1

    Banging video. Made me brush teeth instantly. Subbed

  • @bravebrush5057
    @bravebrush5057 3 роки тому +1

    So good quality!

  • @RobiTheophilus
    @RobiTheophilus 3 роки тому

    Love this. Thank you!

    • @Clockworkbio
      @Clockworkbio  3 роки тому

      No--thank YOU for taking the time to reach out!

  • @WritersInkTHEWORD
    @WritersInkTHEWORD 11 місяців тому

    very good just what I was looking for thankyou

  • @motherloverkiller
    @motherloverkiller 4 роки тому +2

    This channel is finna blow up

  • @MrKAPESHKA
    @MrKAPESHKA 3 роки тому

    great video!

  • @germaniumdiode
    @germaniumdiode Місяць тому

    Such an amazing show

  • @alexaa8572
    @alexaa8572 Рік тому +1

    as a dentist, this is amazing. well done

  • @community1854
    @community1854 2 роки тому +1

    This is gold

  • @ryanatkinson2978
    @ryanatkinson2978 27 днів тому

    Has this channel finally been blessed by the almighty algorithm? I hope he starts uploading again!

  • @timreagan777
    @timreagan777 2 роки тому

    this video was fucking great! solid information and well spoken!

  • @AdityaPratapSingh-ss8wg
    @AdityaPratapSingh-ss8wg Рік тому +1

    Wow awesome guy awesome script... Great

  • @mohammadahmad4972
    @mohammadahmad4972 2 роки тому +3

    First of all thank you for this useful presentation I really enjoyed the chemistry part but around fluoride may cause damage or discolored your teeth it may cause that if someones receive excessive fluoride systematically during tooth development stages so excessive fluoride in your mouth do not cause discoloration unless you swallow it at time where tooth are in develop stage before they erupt

  • @glebbeer4160
    @glebbeer4160 3 роки тому +3

    Привет из Беларуси спасибо за это видео!

  • @user-sh1tg4kb4o
    @user-sh1tg4kb4o 3 роки тому +1

    A huge thanks to the person who shared this video on reddit

  • @daviddimbleby6725
    @daviddimbleby6725 Рік тому

    Thanks for the info ! 👍 your very humble dude it's refreshing ✌

  • @RenayEmond
    @RenayEmond 3 роки тому +12

    Great Channel!
    Can see why John Green gave this a recommendation
    Subscribed for more Awesome Learning 😁
    👏🏼✌🏽❤🙏🏽

  • @BRAND0N...
    @BRAND0N... 16 днів тому +1

    Could you cite any research that indicates or proves that ingesting the specific type of fluoride that we drink in our tap water? Also why did you seem to imply that it's the same kind that's in our toothpaste?

  • @user-xi3mk8kp4j
    @user-xi3mk8kp4j 5 місяців тому

    thank you i learned alot from ur video .. would like to ask if u have topic related to fluorosis .. could u talk about it why we get the white yellow spot related to fluoride consumtion. thank u

  • @teststream2511
    @teststream2511 3 роки тому +1

    Hi from Vert Dider!

  • @santoshsahani4264
    @santoshsahani4264 10 місяців тому +3

    Dental health is power💪

  • @nikitajouchims9584
    @nikitajouchims9584 4 роки тому +1

    I use miswak never had toothpain since.

  • @graemelaubach3106
    @graemelaubach3106 Рік тому

    Best biochem channel right now. Perfect animation, informative and just, so sexy. This will blow up soon.

  • @wyla5896
    @wyla5896 Рік тому +2

    Could other ions (strontium, chloride, heck- uranium theoretically) be used to replace the OH in apatite for an even more acid-resistant matrix than fluoride? Why don’t we use other ions besides fluoride?

    • @lolerie
      @lolerie Рік тому +1

      Because we now know nano-mhap is much more safe and fast and nice than F.

    • @storyls
      @storyls 7 місяців тому +1

      Because fluoride is the best.
      You can use chloride to make clorapatite but that is weaker than hydroxyapatite. Hypothetically you could use bromine or any other halogen too but that would be even worse.
      Fluorine is the most electronegative element in the periodic, it pulls together those ions because it really wants their electrons. That’s just it.

  • @ashleycarter1661
    @ashleycarter1661 3 роки тому +3

    It bothers me how the woman is brushing her teeth incorrectly with that electric toothbrush!!

  • @Jakensik
    @Jakensik 3 роки тому

    What about streptococcus salivarius m18?

  • @TheOgi22
    @TheOgi22 21 день тому

    03:35 is posible to make this font smaller?
    :)

  • @igloozoo3771
    @igloozoo3771 10 місяців тому +2

    So why not use Hydroxyapatite toothpaste instead of Fluoride?

    • @Nxck2440
      @Nxck2440 2 місяці тому +1

      Hydroxyapatite is a crystal, how are they going to put that in a tube?

    • @TS-jm7jm
      @TS-jm7jm 19 днів тому

      ​@@Nxck2440grind it up into a fine powder and add it to the liquid mix

  • @MrKAPESHKA
    @MrKAPESHKA 3 роки тому

    thnks from Kiev

  • @gx1501996
    @gx1501996 3 роки тому

    Your website links say Website Expired

  • @seanm7553
    @seanm7553 Рік тому +1

    U could have explained why stannous fluoride works so much better than sodium fluoride.

  • @gaureearolkar1522
    @gaureearolkar1522 16 днів тому

    many yt vdo about whitening teeth using vinegar, baking soda, etc....
    wonder what damage they would cause to teeth?

  • @Khmerstreets
    @Khmerstreets 24 дні тому

    I never brushed with toothpaste before, lol i guess i should start doing that

  • @snowps1
    @snowps1 2 роки тому +2

    Does fluoridated water turn your teeth yellow over time?

    • @lolieslover2179
      @lolieslover2179 2 роки тому

      no the quantity of fluoride in both tape water and toothpaste have no harm on your teeth and your health

  • @adrianmoisa2281
    @adrianmoisa2281 2 роки тому

    No more videos :( ?

  • @lyhongleft3676
    @lyhongleft3676 2 дні тому

    What if you don't eat carbs and eat lets say, meat instead?

  • @MrRaybrown007
    @MrRaybrown007 5 місяців тому

    I wonder about fluoride in toothpaste, I feel just not eating sugary foods would be better.

  • @mechez774
    @mechez774 23 дні тому

    I wonder if the fluoride has to be applied topically for fluorapatite formation, or whether there is also some mechanism whereby ingested fluoride is transported from the digestive system back to the mouth. It seems like this is part of the claim of water fluoridation advocates

    • @denofpigs2575
      @denofpigs2575 11 днів тому

      Water fluoridation has never been about improving your health.

  • @silverlyder
    @silverlyder 8 місяців тому

    6:20 me too I cant find a definitive answer

  • @user-yb4om7zd7b
    @user-yb4om7zd7b 3 роки тому

    Так поддержал канал, осталось выучить английский. Спасибо vert dider за перевод

  • @jorge.tavares
    @jorge.tavares 16 днів тому

    naaaaaooo so tem 12 videos nesse canal 😭😭😭😭😭😭

  • @pab166
    @pab166 3 роки тому

    From Vert Dider.

  • @misty_jeera
    @misty_jeera 3 роки тому

    Got here from a Corporis video : )

    • @Clockworkbio
      @Clockworkbio  3 роки тому +1

      hell yea friend--thanks for letting me know! Hope this channel someday catches up to him in quality!

  • @nandavenki3913
    @nandavenki3913 4 роки тому

    Are u a researcher?

  • @Liineeeee
    @Liineeeee 18 днів тому

    my real question is not why fluorine is better but more why didnt our body already got fluorine there. Well I guess it doesnt like dealing with fluorine because fluorine is... a bit mean.

  • @Tomatos1234
    @Tomatos1234 Рік тому +12

    A customer cured is a customer lost, just remember that.

    • @HUEHUEUHEPony
      @HUEHUEUHEPony 24 дні тому

      I'm not American, so this doesn't apply

  • @darnelljackson2160
    @darnelljackson2160 Рік тому

    skip to 0:45 to get to the actual topic.

  • @pyroromancer
    @pyroromancer 2 роки тому

    _interlinked_
    *within cells interlinked within cells interlinked within cells interlinked*

  • @AJ-rd4ng
    @AJ-rd4ng Місяць тому

    Iiiiiirons iiiiiirons iiiiiirons ⚒️⚒️⚒️

  • @PewDiePie777
    @PewDiePie777 Місяць тому

    Btw, if you ever wondered what video would be able to make your type of content blow up. In my experience, it would be something connected with reproducing. It's just a kind of trend I noticed in the most popular UA-cam channels of this thematic. Just an observation.

  • @imveryhungry112
    @imveryhungry112 Місяць тому

    Is flouride good for my teeth or not please just someone answer and help me

    • @macon8638
      @macon8638 Місяць тому

      Yeah it’s good for you’re teeth 🙃 Like everything it’s good in moderation, most places in the world don’t have too much fluoride

    • @DASLAKILL
      @DASLAKILL 13 днів тому

      Fluoride is a neurotoxin, and a waste product of heavy industry. None of it in any quantity is good for you.

  • @stratfilovski6539
    @stratfilovski6539 3 роки тому

    спасибо за полезную информацию. подача отличная! привет из России))

  • @wayneeligur7586
    @wayneeligur7586 8 днів тому

    Only Calcium Fluoride strengthens and protects teeth not the industrial version Sodium Fluoride!
    There is no safe minimum dose of elemental Fluoride!
    I suggest redoing the video after more research.

  • @1337bitcoin
    @1337bitcoin 18 днів тому +1

    2024 comeback???

  • @yerassylmukhamediyar4818
    @yerassylmukhamediyar4818 3 роки тому +1

    Hello from Kazakhstan. Good lack to your channel

  • @myceliation
    @myceliation 23 дні тому

    fluorapatite causes differential erosion of teeth which then further quickly erodes the hydroxyapatite sections of your mouth

  • @Gunzee
    @Gunzee 4 роки тому +1

    Drink carbonated things, even water through a straw & chew gum often.

  • @BlownMacTruck
    @BlownMacTruck Місяць тому +1

    6:21 for someone who supposedly loves learning, please learn how to use “begs the question” correctly. It’s a huge red flag when people who are trying to convey information use this phrase in a completely inapplicable way.

    • @makego
      @makego 27 днів тому

      It has more than one definition. It's not just the rhetorical fallacy. From the OED: 1. (of a fact or action) raise a question or point that has not been dealt with; invite an obvious question.

    • @BlownMacTruck
      @BlownMacTruck 27 днів тому

      @@makego Cite your reference.

  • @JewsRock-ILJ
    @JewsRock-ILJ 24 дні тому +2

    The fluoride will make the dentin in the tooth become brittle and will make it easier to snap the tooth. If you stop consuming sugar and high levels of carbs you won't have to worry about the acid from bacteria decaying the teeth. A good alternative for tooth paste is pure olive oil soap, flossing, hydrogen peroxide, mouthwash, and 40-75% ethanol right after consuming food.

    • @denofpigs2575
      @denofpigs2575 11 днів тому

      I use a homemade toothpaste of coconut oil, hydrogen peroxide, baking soda, and clove oil. Stuff makes my teeth feel pristine.