EPIGENETICS and GENE EXPRESSION A-level Biology. How methyl and acetyl groups control transcription

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  • Опубліковано 9 лис 2024

КОМЕНТАРІ • 45

  • @leahlester2620
    @leahlester2620 4 роки тому +29

    Thank you!! You make this topic seem so simple now☺️

    • @MissEstruchBiology
      @MissEstruchBiology  4 роки тому +2

      Thank you Leah :)
      Glad you have found your 'subscriber choice' video helpful😁

  • @AndrewIu-jq3rt
    @AndrewIu-jq3rt 5 місяців тому +19

    Revision for next week yay

  • @menerrs
    @menerrs 3 роки тому +14

    thank you so much, when i learnt this in school I was overwhelmed by the new vocab but you explained it perfectly!

    • @MissEstruchBiology
      @MissEstruchBiology  3 роки тому +1

      Hello 👋🏻
      That's great 😁 So pleased it helped you understand this topic and the key words

  • @qaisarsbiology5267
    @qaisarsbiology5267 4 роки тому +12

    I was searching for a simple explanation on epigenetics and finally, i got it here.Thank you again

  • @ethancheung114
    @ethancheung114 7 місяців тому +13

    such a hard topic ngl

  • @marckessler3662
    @marckessler3662 3 роки тому +3

    Excellent videos, I am going to show this one to my AP Biology students. Given the quality of your videos, you should have many more views :)

    • @MissEstruchBiology
      @MissEstruchBiology  3 роки тому +1

      Thank you so much. I hope it helps them.
      Hopefully one day I will 😊🤞

    • @gregorysmith1134
      @gregorysmith1134 2 роки тому

      Most people know nothing about molecular biology. This is not a video for the general public, but, rather, for that small percentage of the population who has the background knowledge to understand the subject matter.

    • @rubiksworld2170
      @rubiksworld2170 8 місяців тому +2

      @@gregorysmith1134lol this is just an a level biology video so for 16-18 year olds. And a lot of ppl do a level bio!

  • @itsarmie3162
    @itsarmie3162 3 роки тому +3

    i return again to thank you, bless you! :)

    • @MissEstruchBiology
      @MissEstruchBiology  3 роки тому +1

      You are very welcome! I hope the videos continue to help you.

  • @kingd1738
    @kingd1738 2 роки тому +29

    Oh my lawd im finished tomorrow

  • @tryingtolearnn
    @tryingtolearnn 10 місяців тому +2

    3:57 is there a mistake because it says transcription is going to be hard as there are stronger association of dan and histone but then you say the exact opposite?

  • @VanecheWansi
    @VanecheWansi 6 місяців тому

    This was really helpful

  • @mostafaelboghdady8653
    @mostafaelboghdady8653 2 роки тому +1

    thank you doctor for this helpful video ☺☺☺

  • @angelumeokaleo1859
    @angelumeokaleo1859 2 роки тому +3

    hi I was wondering , if there’s decreased acetylation of histones does that make then bind to DNA Mir tightly or do they bind loosely ?? :)

    • @tania-vq8di
      @tania-vq8di 2 роки тому +1

      i think they bind more tightly due to stronger association!

    • @gregorysmith1134
      @gregorysmith1134 2 роки тому

      More tightly. The less acetylation, the more methylation.

  • @gregorysmith1134
    @gregorysmith1134 2 роки тому +2

    Like your British accent. You pronounce certain words differently than we do in America.

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому

      ahh yeah! Which words? I know in ecology niche is pronounced differently

    • @gregorysmith1134
      @gregorysmith1134 2 роки тому

      @@MissEstruchBiology words such as Methyl. We give it an "eh" sound, whereas you place your accent on the "e". It is difficult to explain in writing. While I have your ear, if I wanted to convert a virus into a retrovirus, would I need to create an operon to code for my Integrase, Protease, and Reverse Transcriptase? It would seem I would need to insert an operator to allow repression until these enzymes are translated and ready to carry out their functions.

    • @winniethepooh8766
      @winniethepooh8766 Рік тому

      @@gregorysmith1134 smart guy

  • @sea5205
    @sea5205 3 роки тому

    You have really helpful videos thanks!

  • @mathur932
    @mathur932 2 роки тому +1

    thank you

  • @rmzfbrmz
    @rmzfbrmz Рік тому +3

    Summary:
    Adding a methyl group to the tail (methylation) maintains the positive charge, making DNA more coiled and reducing transcription. Methyl group isn't positive.
    Adding an acetyl group to the tail (acetylation) neutralises the charge, making DNA less tightly coiled and increasing transcription.

  • @missgirl7879
    @missgirl7879 9 місяців тому

    Im finished for my mocks 😢

  • @Diedieimmerlacht253
    @Diedieimmerlacht253 3 роки тому +1

    The acetyl group is not negative. It just masks the positive charge of histones. Anyway, your videos are awesome.

    • @MissEstruchBiology
      @MissEstruchBiology  3 роки тому +4

      Glad you liked the video. Thanks for your point. For AQA that is the accepted the level of detail. As is often that case with science, GCSE and A-levels are taught at a particular level rather than all the exact details to prevent the courses becoming waaayyy to detailed and too high a standard.

    • @atrappy2077
      @atrappy2077 2 роки тому +8

      if you're such an expert then why u watching bio videos

  • @jonathanhyde3593
    @jonathanhyde3593 4 місяці тому +2

    i’m praying this doesn’t come up tmr

  • @sujansvault
    @sujansvault 2 роки тому

    m lmk

  • @Simi.g
    @Simi.g Рік тому

    thank you