Topic 8 A level Biology - Learn the ENTIRE gene expression topic for A level in an hour!

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  • Опубліковано 13 лют 2022
  • Learn or revise all of topic 8 (Gene expression) for A level biology. I talk you through the fundamentals, but you can watch my other topic 8 videos for the full, in-depth details.
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КОМЕНТАРІ • 134

  • @Ned24824
    @Ned24824 2 дні тому +93

    crazy that im learning this for the first time the night before the exam

  • @Ned24824
    @Ned24824 2 дні тому +22

    Im officially failing this exam tomorrow

    • @fibonacci3138
      @fibonacci3138 2 дні тому +2

      In two hours omg!!! nah we're gonna smash it, god willing any examiners that mark my paper are extremely drunk

    • @saki7596
      @saki7596 2 дні тому

      sigh for real, esp unit 6 lord

  • @ok6694
    @ok6694 3 дні тому +34

    not looking good brev

  • @a1257_1
    @a1257_1 3 дні тому +34

    Pray for me paper 2s tmrw and I’ve never even revised topic 6 or 8 before 💔

  • @lizzyharness4643
    @lizzyharness4643 Рік тому +92

    for anyone here for tomorrows paper 2 don’t worry i will personally be lowering the grade boundaries for u 😍

    • @DoubleAAce
      @DoubleAAce Рік тому +9

      Ill try by best to lower it even more

    • @dfszf4743
      @dfszf4743 2 місяці тому +3

      how did itgo

  • @medicusv61
    @medicusv61 Рік тому +235

    This HAS to be the hardest topic, I've been going through this video bit by bit for like almost a week now!

    • @fefunkey3808
      @fefunkey3808 Рік тому +8

      Hardest?! I think this is the easiest!!

    • @medicusv61
      @medicusv61 Рік тому +42

      @@fefunkey3808 Its easy content wise but ALOT of remembering. :(

    • @Idkchangethislater
      @Idkchangethislater Рік тому +7

      Just boring mate module 5 and 6 mainly 6 are hardest

    • @Celeste_51
      @Celeste_51 6 місяців тому +7

      I agree hardest topic so far! (Apart from respiration oh my gosh)

    • @leoliversage
      @leoliversage Місяць тому +9

      @@Celeste_51 respiration easy compared to this

  • @beccaa7638
    @beccaa7638 3 дні тому +14

    2:23 mutations
    6:52 stem cells
    9:08 transcription and translation
    18:28 gene exp and cancer
    25:46 using genome projects
    28:03 recombinant dna
    50:21 differences in DNA between individuals of same species
    54:40 genetic fingerprinting

  • @jasminesfld7
    @jasminesfld7 2 дні тому +8

    soo behind on this paper and i also have an english exam tomorrow😔dreading it

    • @ellad43
      @ellad43 2 дні тому +2

      literally in the exact same position, i haven't revised at all for english today 😭hopefully we will both be fine

    • @ramengurung9913
      @ramengurung9913 2 дні тому +1

      @@ellad43yeh same. Icl I’m cooked

  • @Hannibalsbreakfast
    @Hannibalsbreakfast 2 роки тому +72

    I honestly was looking for a video that sums up all of gene expression and here it all is >_< Thankyou so much

  • @poppydowse7753
    @poppydowse7753 2 роки тому +29

    thank you i hate this topic so much! by far the hardest!!

  • @tomconway8241
    @tomconway8241 Рік тому +20

    You are a legend - this video is amazing, you have really simplified the topic for me!!

    • @MissEstruchBiology
      @MissEstruchBiology  Рік тому +1

      Thank you!!!! So pleased it helped simplify it all for you 😀

  • @maheenarahman573
    @maheenarahman573 2 роки тому +37

    Thank you so much, I really appreciate your hard work :)

  • @shafinbepary2000
    @shafinbepary2000 Рік тому +7

    the sheer dedication on this! kudo miss

  • @benjaminhirschfield9164
    @benjaminhirschfield9164 Рік тому +6

    great videos miss estruch, thank you for your help!

  • @abcrm101
    @abcrm101 2 роки тому +40

    I have finished the whole series :)
    Time to do the same thing for chemistry
    P.s. thank you so much, you have no idea how much your videos help

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому +7

      I'm so pleased you have found them helpful and wow for managing to watch all of them!!!

    • @abcrm101
      @abcrm101 2 роки тому +1

      @@MissEstruchBiology XD just a bit of time before and after meals

    • @elliesmith7518
      @elliesmith7518 2 роки тому +2

      What channel do you use for chem? Gimme rn

    • @sofiaqueen8635
      @sofiaqueen8635 2 роки тому +7

      @@elliesmith7518 allergy chemistry is really helpful :) he does a few exam boards and runs through all topics

    • @sofiaqueen8635
      @sofiaqueen8635 2 роки тому +3

      Allery* chemistry sorry ahah

  • @isobelcoulls9842
    @isobelcoulls9842 2 роки тому +7

    Thank you! I understand this a lot better now.

  • @katrinabentley
    @katrinabentley 3 дні тому +12

    i wanna scream 😊

  • @noahblackwelll
    @noahblackwelll 2 роки тому +16

    For aqa is this literally everything we need to know

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому +11

      Yes, it's all of the theory. It doesn't include application, required practicals or maths skills though.

  • @abcrm101
    @abcrm101 2 роки тому +12

    This series is awesome
    Thank you so much

  • @jessmitchell3195
    @jessmitchell3195 2 роки тому +2

    Great video! For the marker genes, I though that if the plasmid was taken up by the host cell then they will express GFP or they will be resistant to the antibiotic as they contain the marker gene (instead of disrupt the gene so it isn't expressed) or is it the opposite way round?

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому

      Hey its the opposite way round, as explained in the video..However, read the exam questions carefully to see the information given on where the DNA fragment is inserted.

  • @jess1148
    @jess1148 2 роки тому

    you're amazing thank you!!!!

  • @lucyruddle8521
    @lucyruddle8521 2 роки тому +6

    Hello, thank you for this video! I have a question - at 36 minutes you talk about the modifications being made so RNA polymerase can work properly. Why is it RNA polymerase, not DNA? What is the RNA polymerase being used for? Thanks!

    • @stressedoutkid2415
      @stressedoutkid2415 2 роки тому +7

      DNA polymerase is used for semi conservative replication ONLY. whereas promoter initiates TRANSCRIPTION hence only transcription factors and RNA polymerase can bind to promoter. If DNA polymerase binds to the promoter it will technically inhibit the binding site of the promoter

    • @lucyruddle8521
      @lucyruddle8521 2 роки тому +2

      @@stressedoutkid2415 thank you, that makes sense!

  • @rainbowraider5029
    @rainbowraider5029 Рік тому +2

    is this ok to use for edexcel b

  • @fibonacci3138
    @fibonacci3138 День тому

    Hi miss! at 47:00, are we meant to insert the enzyme gene into the plasmid? isn't it meant to be that the plasmid would already have the gene that codes for lactase and we're adding our DNA fragment to it to see if it disrupts the lactase? It does say that on the image you inserted but the text says otherwise... just checking with you if you see this!

  • @sams582
    @sams582 2 роки тому +1

    at 46:26 how do we know that the bacteria which aren't fluorescing even took up the plasmid at all

  • @fibonacci3138
    @fibonacci3138 2 дні тому

    Now time to procrastinate again till the night before paper 3

  • @yousifmajeed9316
    @yousifmajeed9316 2 роки тому +4

    thanks for this

  • @theendoftimeandme6960
    @theendoftimeandme6960 9 днів тому +3

    At 46:40 is it colourless to blue or blue to colourless?
    the text says from colourless to blue so thats why im confused
    thanks a lot for the vid btw, its a life saver 😭

    • @archiemarshall1533
      @archiemarshall1533 5 днів тому +1

      from colourless to blue, if the fragment is present then it stays colourless as it stops the lactase gene, however if the fragment is not present then it will turn blue as the lactase gene will work

  • @a1257_1
    @a1257_1 3 дні тому +2

    Do we need to know the antibiotic resistant marker genes names?

  • @footballvideoshd6183
    @footballvideoshd6183 2 роки тому +5

    I apologise that my comment is not related to this video. But I wanted to ask in regards to the ELISA test, which is explained in the Monoclonal Antibodies video. After adding the second antibody are you supposed to wash again to remove any unbound antibodies because I believe that that was not included in the method of performing the ELISA test

    • @vermillionxuxusss5801
      @vermillionxuxusss5801 2 роки тому

      Yea u wash after the second one otherwise when u add the substrate next it will break down regardless

    • @footballvideoshd6183
      @footballvideoshd6183 2 роки тому

      @@vermillionxuxusss5801
      How come that's not included in the video?

    • @alaynahurooj1995
      @alaynahurooj1995 2 роки тому

      @Veer Pattni thats in the immunity video

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому +4

      Hello, yes you do wash after both additions. Hope that helps

  • @atrappy2077
    @atrappy2077 2 роки тому +2

    topic 5 next please

  • @ta647
    @ta647 Рік тому

    hi miss, do aqa students not need to know about gene therapy?

  • @harrietrose347
    @harrietrose347 2 роки тому +5

    Hi, sorry this may be a stupid question but is oestrogen binding to a proto-oncogene to cause cancer just a completely random occurrence? Thank you for making these videos as well they are really helpful:)

  • @bobbytoot9858
    @bobbytoot9858 2 роки тому +4

    how much of this is included in the advanced information?

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому +3

      Quite a lot. Gene expression is on paper 2 and gene technologies on paper 3

  • @jeffreylau2010
    @jeffreylau2010 2 роки тому +6

    To clarify: When do you use DNA polymerase or RNA polymerase? (how to remember the difference?)
    (Might be a good TikTok video)

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому +6

      DNA polymerase = for DNA replication
      RNA polymerase = for transcription
      Hope that helps 😊

  • @katieweymouth3103
    @katieweymouth3103 2 роки тому +3

    hi miss, what unit will you be uploading next?

  • @yabombo8145
    @yabombo8145 2 роки тому +1

    Cheers lad have a good en

  • @soph2809
    @soph2809 Рік тому

    in 46:36 what if it isn't glowing because it hasn't taken up the plasmid? sorry

  • @samimuhammad1201
    @samimuhammad1201 2 роки тому +2

    Nice video

  • @pastaslut
    @pastaslut 7 місяців тому

    This is actually so so helpful thank you so much!

  • @doodlebob1898
    @doodlebob1898 2 роки тому +2

    Hi miss can you do all the other topics you have not done

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому +1

      Hello, yes 😊 I'm doing one per week

    • @doodlebob1898
      @doodlebob1898 2 роки тому +2

      @@MissEstruchBiology ty

    • @robyntappern7637
      @robyntappern7637 2 роки тому +2

      @@MissEstruchBiology hey Miss thank you so much for your videos, which topic will you be doing next?

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому +2

      @@robyntappern7637 I'll put it to a vote!

  • @radhaxel
    @radhaxel Рік тому +1

    is this for aqa?

  • @vermillionxuxusss5801
    @vermillionxuxusss5801 2 роки тому +5

    I got an idea, how bout you make a video for each paper with only the stuff on advanced information

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому +11

      haha its like you've seen my diary! That's coming in a month

  • @AjayPatel-xv4dk
    @AjayPatel-xv4dk Рік тому +1

    MediiiiCoach getting the recognition

    • @saddish2816
      @saddish2816 2 місяці тому

      Did u manage to sleep with any white girls in uni?

    • @basset5889
      @basset5889 7 днів тому

      @@saddish2816 huh

    • @saddish2816
      @saddish2816 6 днів тому

      @@basset5889 ?

  • @mariambenafia1385
    @mariambenafia1385 2 роки тому +1

    Topic 2 next? Or 4

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому +1

      Potentially 2!

    • @atrappy2077
      @atrappy2077 2 роки тому +1

      u not interested in topic 5? makes up a lot of paper 2 and paper 3....

  • @ludicrous_doughnut3533
    @ludicrous_doughnut3533 3 місяці тому +1

    no timestamps 💀

  • @chunkplunk
    @chunkplunk 2 роки тому +7

    this looks painful

  • @Elias.04
    @Elias.04 Рік тому +5

    Gene technologies is easily the worst topic 🥲

    • @MissEstruchBiology
      @MissEstruchBiology  Рік тому +3

      it's a tough one!

    • @Elias.04
      @Elias.04 Рік тому +1

      @@MissEstruchBiology You make it easier though, thank you so much 🥰

  • @samimuhammad1201
    @samimuhammad1201 2 роки тому +3

    Nice video