Very thought-provoking classification. 👏 Had to see the video twice! One Question: 🤔 If cancer cells first manipulate the osteoclasts and the progenitors of fibroblasts are the same as osteoblasts, is it correct to say that the early phase of marrow involvement for metastatic prostate cancer would be like this: PSMA-PET: + Bone scan: - FDG-PET: + (osteoclastic phase, if agressive phenotype and high GG) FAPI-PET: - (my main question) WB-MRI: -/+ (not hypercellular yet, similar to osteoclastic-only activity in the fat-predominant phenotype) CT: mildly hypodense, yet not lytic
Thank you i have agressive breast cancer and my knees and shin bones hurt so bad it makes me cry
WOW, great information, there is so much knowledge out there is incredible!
Glad it was helpful!
Very thought-provoking classification. 👏
Had to see the video twice!
One Question: 🤔
If cancer cells first manipulate the osteoclasts and the progenitors of fibroblasts are the same as osteoblasts, is it correct to say that the early phase of marrow involvement for metastatic prostate cancer would be like this:
PSMA-PET: +
Bone scan: -
FDG-PET: + (osteoclastic phase, if agressive phenotype and high GG)
FAPI-PET: - (my main question)
WB-MRI: -/+ (not hypercellular yet, similar to osteoclastic-only activity in the fat-predominant phenotype)
CT: mildly hypodense, yet not lytic
GREAT TALK!!!! thank you very much
If a ct scan reveals osteolytic and osteoblastic lesions along vertebral areas, is this a indicating mets?
Yes. If there's a history of Cancer
I don’t understand any of this
Look at the playlist on metastases where I break it down into 3 sections. That should help you
❤