just want to say a massive thanks for all the help from your channel over the past two years now that I've finally completed biology A level, I couldn't have done it without your help and paper 3 was a good one to finish with
For the importance of receptors could to talk about decrease and increase of blood glucose concentration, presynaptic and post synaptic membrane and phagocytosis
For the receptor question could you talk about light receptors in the eye (rod and cone cells) and also cholinergic synapses or neuromuscular junctions as ACh binds to the cholinergic receptor?
There isn’t hydrogen bonding that occurs with cisplatin, its the Cl atoms in the complex that binds to guanine, hydrogen bonds are not important nor relevant
@@Cloe092 Doesn’t cisplatin work by causing DNA strands to kink so they can no longer unwind as hydrogen bonds aren’t overcome. It’s definitely a bit of a stretch though
yh i think so, you can end your para abt DNA with: hydrogen bonds are important because without them, cells wouldn't be able to divide (obv elaborate on this a bit). for example the use of anticancer drugs such as cisplatin that work by preventing hydrogen bonds forming in DNA - this is evidence that hydrogen bonds are essential in the DNA and cell replication
Could I talk about NADH, NADPH and cAMP as carbon containing molecules? If so could I just state that these molecules contain carbon because we're not supposed to know the structures of these?
For the receptors topic could you also do transmission of an action potential along a synapse as their are receptors on the chemical-gated sodium ion channels on the postsynaptic membrane?
@@mimzyy3362 you can link it to eyes or control of heart rate. I personally like to always link this ones to the eyes and how you need enough iodopsin to be broken down to initiate an action potential otherwise you wouldnt be able to see. Just make that a little more waffly and your done.
Hi miss, I just wanted to ask if you can make your ao2 multiple points, e.g. the importance of atp in muscles contraction and also in the light independent reaction
For the first essay could you just do an essay of the importance of ATP in different areas of the spec or would you recommend doing a range of molecules.
For the importance of lipids could you link it to chemiosmosis where the membrane isn’t permeable to hydrogen ions so they can’t simply diffuse because they aren’t lipid soluble, and have to pass through atp synthase so results in atp production to provide energy for metabolic processes?
Hi Miss, are there any points from out of the spec that we can shuffle around and use to apply to most/any essays? I would really appreciate any response thank you!!
no - the importance part of the paragraph is the AO2 (application) marking point - if you only talk about what the things do you are only getting AO1 (knowledge) marks. you need to talk about what the things do and THEN why that is important: for example it is important that glucose is transported across membranes through co-transport (then go into detail about the sodium potassium pump etc) BECAUSE glucose is needed for glycolysis which is the first step of respiration. then you go into a bit of detail about glycolysis producing pyruvate which is used in the link reaction etc
what would you say for the importance part for pacinian corpuscle? i always end it with something like: 'to protect tissues from damage' but my teacher always says this is not A-level standard
Thank you so much for these amazing videos, I just had one question can you talk about how ADH increases the permeability of the DCT and CD as well as mentioning aquaporins? Also can you mentions the importance of both the receptors on the DCT and CD and the osmoreceptors as they link together ?
this is my paragraph on osmoregulation for an essay on the importance of osmosis, hopefully it helps a bit? Osmoregulation is the process that controls how much water is lost in animals via urine and is vital for maintaining isotonic conditions in the blood. When the water potential of the blood falls too low (becomes hypertonic), osmoreceptors in the hypothalamus shrivel up. In response to this, more of the hormone ADH is produced. The ADH is released by the pituitary gland, and then travels through the blood to the nephron in the kidney, where it binds to complementary receptors in the walls of the distal convoluted tubule (DCT) and the collecting duct (CD). This then activates phosphorylase enzymes within the cells, which causes vesicles containing aquaporin protein channels to fuse with the cell membrane. This results in more embedded aquaporins, which allows more water to leave the DCT and the CD via osmosis into the bloodstream. This prevents needed water from being lost via the urine, and ensures that the bloodstream maintains mostly isotonic conditions - therefore preventing the plasmolysis (and cytolysis) of cells. i've also used this paragraph (though slightly changed to change the focus) for an essay on receptors and one on interactions between organisms and their (internal) environment
@@mariamfarid5941 if osmoregulation didn't take place, the water potential of blood would either fall too low or rise too high, so cells would undergo cytolysis (because they're animal cells and don't have a cell wall) or plasmolysis the receptors on the DCT and CD are important because they activate the phosphorylase enzymes, which causes the aquaporins to fuse with the cell membrane and allow the water potential of the blood to return to more isotonic conditions does that help? sorry i'm not sure if i'm explaining this super well
If I was writing a paragraph on proteins or starch etc would including how to test for them be irrelevant as it's not to do with their importance? Or is there no harm in including it?
Isn’t the last title just the same as the importance of responder to internal and external responses in organisms the title in the video you did in your last essay on “predictions”
Can you talk about auxins (IAA), hormones (oestrogen), neurotransmitters (ACh) since they all contain C? This is for the importance of c containing compounds essay
when u plan for the importance of receptors u plan one paragraph on pacinian corpuscles and another on chemoreceptors but aren't they both in topic 6? Are you allowed to talk about two areas of the same topic I thought u had to pick different ones. Sorry if stupid question
You can never really tell accurately how an exam went. But even I'd one went badly, it doesn't mean the rest will and they can pull up you're overall mark still..You've got this 💪🏻💪🏻
Watching this after just finished doing chemistry paper 2 and bio is tomorrow, send help 💀
no im so scared
good luck!
Same. I’ve got 5 exams this week halp
@justmonicaaa5915 Me too, half my friends have finished already and I'm still on the grind
That chem paper is still haunting me
i’ve been pretending like it doesn’t exisy i need to lock in so bad 😭
you just like me fr
You've got this, rip that bandaid off 💪🏻
just want to say a massive thanks for all the help from your channel over the past two years now that I've finally completed biology A level, I couldn't have done it without your help and paper 3 was a good one to finish with
Thank you so much for taking the time to send such a lovely message 😊
For the importance of receptors could to talk about decrease and increase of blood glucose concentration, presynaptic and post synaptic membrane and phagocytosis
Yes
there is a special place in heaven for you 🙌
Real
For the receptor question could you talk about light receptors in the eye (rod and cone cells) and also cholinergic synapses or neuromuscular junctions as ACh binds to the cholinergic receptor?
yeah that is a good one
thank you for this miss, and your dna tattoo is so cute!
Do you think you could talk about cisplatin for the hydrogen bonding essay as something outside of the spec?
There isn’t hydrogen bonding that occurs with cisplatin, its the Cl atoms in the complex that binds to guanine, hydrogen bonds are not important nor relevant
@@Cloe092 Doesn’t cisplatin work by causing DNA strands to kink so they can no longer unwind as hydrogen bonds aren’t overcome. It’s definitely a bit of a stretch though
yh i think so, you can end your para abt DNA with: hydrogen bonds are important because without them, cells wouldn't be able to divide (obv elaborate on this a bit). for example the use of anticancer drugs such as cisplatin that work by preventing hydrogen bonds forming in DNA - this is evidence that hydrogen bonds are essential in the DNA and cell replication
Could I talk about NADH, NADPH and cAMP as carbon containing molecules? If so could I just state that these molecules contain carbon because we're not supposed to know the structures of these?
i doubt you would have state it as this is biology and all biological molecules contain carbon
For the receptors topic could you also do transmission of an action potential along a synapse as their are receptors on the chemical-gated sodium ion channels on the postsynaptic membrane?
yeah, that would be a good one
@@MissEstruchBiology what would be the importance for this one?
@@mimzyy3362 you can link it to eyes or control of heart rate. I personally like to always link this ones to the eyes and how you need enough iodopsin to be broken down to initiate an action potential otherwise you wouldnt be able to see. Just make that a little more waffly and your done.
@@flamez_beatz9116thank you so much
Hi miss, I just wanted to ask if you can make your ao2 multiple points, e.g. the importance of atp in muscles contraction and also in the light independent reaction
For the first essay could you just do an essay of the importance of ATP in different areas of the spec or would you recommend doing a range of molecules.
For the importance of lipids could you link it to chemiosmosis where the membrane isn’t permeable to hydrogen ions so they can’t simply diffuse because they aren’t lipid soluble, and have to pass through atp synthase so results in atp production to provide energy for metabolic processes?
Hi Miss, are there any points from out of the spec that we can shuffle around and use to apply to most/any essays? I would really appreciate any response thank you!!
Would it be good to link the lipid and phospholipid membrane to controlling transcription and oestrogen?
could u talk about reflex arcs in the importance of pacinian corpuscles
Will you be making another essay video before the Paper 3, Miss?
yes! One about mistakes to avoid
@@MissEstruchBiology Perfect, I look forward to watching it. Thank you for all your work.
When they ask about “the importance” is the pretty much the same as asking “what do these things do?”
no - the importance part of the paragraph is the AO2 (application) marking point - if you only talk about what the things do you are only getting AO1 (knowledge) marks. you need to talk about what the things do and THEN why that is important: for example it is important that glucose is transported across membranes through co-transport (then go into detail about the sodium potassium pump etc) BECAUSE glucose is needed for glycolysis which is the first step of respiration. then you go into a bit of detail about glycolysis producing pyruvate which is used in the link reaction etc
more like what do they lead to
You basically need to say 'why do animals/cells need to do this to survive'
what would you say for the importance part for pacinian corpuscle? i always end it with something like: 'to protect tissues from damage' but my teacher always says this is not A-level standard
Def a tough one, I’d do a similar thing to the video and say muscles contract to move away from pressure and prevent cell membranes being damaged
i saw something saying to link it to competition/ natural selection! organisms can move away from harm and reproduce etc etc
Is this the predictions like you did last year because you saved so many peoples lives with them predictions
Thank you!
You're welcome!
will u be making a prediction video? for the 25m
for importance of C bonds could you talk about the effect of Methly groups joining cytosine ? its technially a carbon bond lol
Thank you so much for these amazing videos, I just had one question can you talk about how ADH increases the permeability of the DCT and CD as well as mentioning aquaporins?
Also can you mentions the importance of both the receptors on the DCT and CD and the osmoreceptors as they link together ?
this is my paragraph on osmoregulation for an essay on the importance of osmosis, hopefully it helps a bit?
Osmoregulation is the process that controls how much water is lost in animals via urine and is vital for maintaining isotonic conditions in the blood. When the water potential of the blood falls too low (becomes hypertonic), osmoreceptors in the hypothalamus shrivel up. In response to this, more of the hormone ADH is produced. The ADH is released by the pituitary gland, and then travels through the blood to the nephron in the kidney, where it binds to complementary receptors in the walls of the distal convoluted tubule (DCT) and the collecting duct (CD). This then activates phosphorylase enzymes within the cells, which causes vesicles containing aquaporin protein channels to fuse with the cell membrane. This results in more embedded aquaporins, which allows more water to leave the DCT and the CD via osmosis into the bloodstream. This prevents needed water from being lost via the urine, and ensures that the bloodstream maintains mostly isotonic conditions - therefore preventing the plasmolysis (and cytolysis) of cells.
i've also used this paragraph (though slightly changed to change the focus) for an essay on receptors and one on interactions between organisms and their (internal) environment
@@izzymccarthy8335 thank you so much but what about the importance of this ?
@@mariamfarid5941 if osmoregulation didn't take place, the water potential of blood would either fall too low or rise too high, so cells would undergo cytolysis (because they're animal cells and don't have a cell wall) or plasmolysis
the receptors on the DCT and CD are important because they activate the phosphorylase enzymes, which causes the aquaporins to fuse with the cell membrane and allow the water potential of the blood to return to more isotonic conditions
does that help? sorry i'm not sure if i'm explaining this super well
@@izzymccarthy8335 thankyouuuu
@ 22:11isnt it noradrenaline which gets released not acetylcholine
thats what i thought too
Yh acetylcholine is inhibitory so that'd slow it down?
Are you able to mention chemoreceptors and pacinian corpuscles in the same essay since they are both in topic 6?
you can cuz they are diff spec points
L predictions
If I was writing a paragraph on proteins or starch etc would including how to test for them be irrelevant as it's not to do with their importance? Or is there no harm in including it?
Isn’t the last title just the same as the importance of responder to internal and external responses in organisms the title in the video you did in your last essay on “predictions”
Can you please provide more essay samples?
more videos like this you mean?
@@MissEstruchBiology i think they mean more exemplar/model essays :)
I meant more model essays
Can you talk about auxins (IAA), hormones (oestrogen), neurotransmitters (ACh) since they all contain C? This is for the importance of c containing compounds essay
yeah! Anything that contains carbon would be relevant
would you be able to use all of those topics in the same essay for carbon containing substances as they’re all from topic 1?
yes, as long as its not the same sub section of each topic
@@MissEstruchBiology okay thank you! by that do you mean you could only do one topic from 1A for example, or only one from 1A.1 ??
@em-kc7iq hey each purple box on the spec basically i think thats what my teacher was telling us? Not sure! But it should be that
can we talk about receptors in synaptic transmission??
yes!
do you have to include both A1 and A2 topics to get a high mark or is it just advised
No, there is no requirement to split it equally between the topics or the Y12/Y13 topics. Just has to be relevant and not the same spec point.
Telling u it’s gonna be receptors.
nope
its possible
@@emimumu why do you think it won't?
With the carbon question, can I talk about the Krebs cycle
I’d say yes you can!
Can I write 6 or 5 marker answers as bullet points
no, you can't bullet point the essay
That caps you at 5 marks
hi miss if an essay on carbon dioxide came can we talk about eutrophication or is that topic too small
isn't that GCSE
@@ManalHassan-zf6xt is it? I’m not sure
@@ayeshaa7334 It is
@@ManalHassan-zf6xtit’s a level too..
when u plan for the importance of receptors u plan one paragraph on pacinian corpuscles and another on chemoreceptors but aren't they both in topic 6? Are you allowed to talk about two areas of the same topic I thought u had to pick different ones. Sorry if stupid question
Yes that's allowed, it can't be the same spec sub section
ok thanksssss
has importance of proteins come up?
yes
@@alexandra129 what year
@@uhrinq6102 2019 and 2023
@@emimumuit didn’t come up in 2023? It was importance of membranes+ interactions between organism
@@emimumuand 2019 was bonds/bonding and DNA
cooked
Does the sympathetic neurone not release noradrenaline?
yeah, you could add that too. That's rarely on question mark schemes so I didn't add it, but you can do
no way u have a dna tattoo girl
ew
@@stwjeongguk3171 bros acting like jk doest have 7 million tattoos
I’ve done an exam last Monday and completely messed up - it makes looking at the textbook impossible and scary 💀🥲
Its okay just try your best and treat each exam like its the first one, you can do this
such great and lovely advice
You can never really tell accurately how an exam went. But even I'd one went badly, it doesn't mean the rest will and they can pull up you're overall mark still..You've got this 💪🏻💪🏻
@@buffenfinessed thank you, I'll try 💕
@@MissEstruchBiology thank you, I'll try to do better on the next one 💕