Fructose & Survival | Drop Acid
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- Опубліковано 14 лип 2024
- While so much is written these days calling attention to the significant threat posed by fructose on our metabolic health, it’s important to put this into historical context. As we look back in time, it is revealed that the consumption of fructose, a sugar found in fruits, was a powerful survival tool. Our hominid and primate ancestors would typically encounter fructose-containing foods in the late summer and early fall when fruit ripened. Ripened fruit triggered our long-standing sweet tooth, which, in and of itself, was an important part of our survival hard wiring.
Sweet foods told our physiology two important things. Firstly, that this is a food that is safe. Generally, in nature, anything that is sweet isn’t threatening. The second thing that foods containing fructose would tell our ancestors was that winter was coming. Fructose triggered the physiology of our ancestors as well as each and every one of us to make fat, store fat, increase blood sugar production, and reduce the metabolic rate, all factoring in to keep us alive during times of food scarcity.
The effects of fructose on our physiology are profound and served us well. In fact, so powerful is this effect that our bodies harness this activity even when we don’t consume fructose, again as an important survival mechanism for time of food or water scarcity. In the absence of dietary fructose, when the human body senses various stresses like dehydration or hypoxia, we actually create fructose and activate all the downstream survival mechanisms like making fat, increasing blood pressure and raising blood sugar. Yes, our bodies can create fructose from glucose through the polyol pathway. And while being able to name the pathway isn’t likely to serve you to any great degree, knowing what activates this pathway has profound implications.
Please enjoy this video. Yes, we get that fructose consumption opens the door to metabolic mayhem. But now we learn how our bodies create fructose, and most importantly how this turns on the production of the very threatening metabolite, uric acid. And uric acid itself goes on to further amplify the very production of its own precursor - fructose! It’s not a pretty picture, but understanding how this all comes together brings empowering new tools to bear on our efforts to regain control over our metabolic destiny.
Learn more in Drop Acid: www.dropacidbook.com
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"to answer this question we must turn to our friend Mr. Camel" great 🙌.
Thank you for the knowledge drop. I'll be sure to check out your book!
WOW! What an informative video! This information for me that is very timely! I am a T2D with HTN and am on a low-carb diet and am exercising several times a week. The takeaway point for me is to drink the appropriate amount of water for my height, weight, and activity level!
Have never realised that our body created fructose. Thank you for this informative podcast.
Thanks for watching!
Just purchased your book along with a few others. I am working on a private class paper on this topic and will be citing your work among many other. There is a lot to learn. Thank you.
Thank you Dr David for sharing the amazing research about the factors regulating serum urate concentrations, will be careful about the high fructose consumption , Do "Drop Acid " also talks about the behavioral and lifestyle changes we need to adopt for keeping the uric acid levels low.
Just made me go get my Uric Acid checked - 4.2 in a 4-8 range ! Never had it checked before and I’m 58 . Great info will purchase book too !
Glad to hear it!
@@DavidPerlmutterMD I do who however disagree with avoiding shellfish, shrimp,meat ,and organ food to avoid Uric Acid . I eat these foods frequently and they’re staple foods for me . My fasting insulin is under 2 . My A1c is 4.8 as mentioned my Uric acid is 4.2 . On a 4-8 scale .
I have had mine checked for years and ignored it thinking it was just about Gout. It has been from 4.6 to 5.3. I am 5.0 now. I understand it can go up for post menopausal women.
I am shocked regarding that statement that our bodies can manufacture fructose! This is truly amazing for me as I have eliminated fructose from my diet and yet still have high levels of Uriel acid at 5.3.
Amazing
This exactly explains what I am seeing in my body but was unable to understand what is going on. I am eating lots of salty food and lots nuts in the last 2 weeks. And I observe that I start to have a bigger tummy.
Thanks
More evidence of the amazing adaptability of the human body to weather times of scarcity. Anecdotally, I find when I fast for extended periods of time or maintain a ketogenic state which induces lipolysis that I am less thirsty than when I am eating (esp. carbs). This is a great synopsis of the biochemical mechanism for why that may be, Thank you!
The discussion about getting water from fat finally cleared something up for me.. when I am fasting I don't need that much water. I have like 5 glasses of water and my piddle runs clear. I always thought it was something about me. When I eat carbs I don't piddling and it is much more colored.
This video alerts us to understand that everything has its place in terms of body functions and survival. Even fructose. In moderation of course.
The trouble for us comes from when we mess it up through excess and ignorance. We have manufactured abundance, convenience, addictiveness, and have over egged the pudding. We have equipped ourselves with limitless supply but without the understanding of how to use it and what we are really doing to the equilibrium.
I believe Zoe Harcombe summed it up:
“Man is the only chronically sick creature on the planet. Could this be because man is the only creature clever enough to make his own food and stupid enough to eat it.”
My copy of Drop Acid is on order. Looking forward to reading it!👍
I have just recieved your book and about to read it. I had a really bad gout attack, and have quite a big tophi lump. Doctors advising long term medication although I'm not a fan of medication. I'm hoping your book will help my situation. I'm only 47, very strong, hardly ever drink. But I do consume huge amounts of sugar. This is because I do construction work and need high calories to keep going. Because my weight is normal I didn't think sugar was an issue, but clearly it is. Gout is awful ☹. My mission to never have an attack again, and to do this without medication.
Amazing info. So the best course of action to combat this process is to stay hydrated?
That ALWAYS helps, so does eating a diet low in fructose.
Sorbitol is used as an artificial sweetener. Now I learn we can convert it to fructose. Yuck.
Please more videos like this.
Lots more to come!
Can Wim-Hof alkaline breathing exercises and cold exposure help reduce Uric levels? How about intermittent fasting?
So, dry fasting is not recommended then, because of dehydration?
Is this info mainly from Dr. Johnson? What is the added value of your book? Tx
👋👋👋💜
I just wanted to add that table sugar is half FRUCTOSE half glucose. I have stopped eating fruits, and as a person living in Brazil, I´m totally counter stream as everybody here praises all kind of fruits, specially the tropical ones.
Great info. What do you think of Dr Paul Saladino saying incorporating fruit & honey is ok with his carnivore lifestyle?
I've reversed my position on honey! Now an ok sweetener if needed.
Amazing information. One Question. IS protein also contribute to Uric acid formation because most of time people with uric acid ,Dr ask them to stop Protein rich food ?
I think it's the purines in protein rich foods (animal protein I believe) I would double check though 😉
@@jenniferlabrum2277 yes please . Check . Thanks for information
If we are to have a low fructose diet does that mean we should not eat fruit?
Low-sugar fruits are a great choice.
So can we eat fruits? If yes what especially? Thank for the Info Dr.
More on that: www.drperlmutter.com/if-fructose-is-so-bad-should-i-eat-fruit/
@@DavidPerlmutterMD Thank you Sir!
Does this mean one should not eat fruit? Fruit turns into fructose- right?
Low-sugar fruits in moderation are acceptable.
@@DavidPerlmutterMD thanks for replying.
I’m so confused about fructose, I thought the fructose is the worst sugar for our body which our brain can’t use it without processed from liver, it also drives our insulin up especially for the diabetic patients to be insulin resistant
Thank you for sharing though !
I am just going to say the information about our bodies making fructose and the idea that salt can do it, I am sorry, just does not pass the smell test. It doesn't make evolutionary sense and that always gets my suspicions up. I am not saying people are trying to deceive I just think the science will turn out to be wrong. I don't see Bears looking for Potato Chips prior to hibernation. My only guess is that our bodies convert excess glucose or excess salt to fructose as an emergency way of turning it into fat and getting out of the blood stream (via turning it into fructose which activates the fat storage pathway).