Increase Your Mitochondria, Your Body Will Thank You | The Acid Drop
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- Опубліковано 30 чер 2024
- As it turns out, mitochondria are essential for cellular function, and virtually every cell in the human body. We just learned about some exciting research whereby a dietary intervention can in fact dramatically increase the number of mitochondria in immune cells. That is certainly a plus. There’s some great information here.
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A low sodium diet is only for people that are mainly sedentary. For those of us who exercise and stay active, a higher sodium (sea salt) diet is much more preferred.
same applies for low carb diets
you need potassium to balance sodium
@@AlanNguyenMDabsolutely! I get @4-5g daily just in my homemade electrolyte drink as potassium nitrate, hence my nitric oxide also tests high. Life is hard 😅
Sources? Thanks
Thanks Dr. Perlmutter..!
Questions on a few items:
1) In study low sodium diet defined as below 6g per day. That is 6,000 mg a day which is huge number..! If we are avoiding processed foods, eating whole food, and maybe only adding modest amount of let's say Himalayan pink salt to our diet, most of us will be way below 6,000 mg of sodium daily..!
2) Study defined low fructose as below 20 g of fructose daily. It would have been helpful if you would put that into perspective. Quick study on high fructose foods identifies banana with about 6 g of fructose. Of course we should minimize fruit juices, processed foods containing high fructose corn syrup, etc., but my understanding is 2-3 pieces of whole fruit a day should keep us way below 20 g fructose daily, as whole fruit often contains fiber, other nutrients, that can act as buffer to modulate blood sugar to keep in acceptable range.
The scope of this video may not have included the above two items, but I found myself wanting while watching video due to no context provided on practical ways to adjust our eating habits to stay below 6,000 mg sodium and 20 g fructose daily.
Also, it would have been great to give viewers some dot points on other topics to improve mitochondrial function, and mitochondrial production, so viewers could do additional research on supporting optimal mitochondrial function as we age.
Thanks again..!
I think those of us that eat only whole nutrient dense foods can use Real Redmond salt on our food freely and still be way under 6g of sodium per day.
No.
Very helpful. Any ideas on how to calculate how much extra a person who is sweating a lot under the sun in a manual labour job along with heavy resistance training in the evenings might need? Obviously impossible to tell without exact details, just interested to know what you think.
@@bobcooterTry 1 tsp and see how it feels. You may need more than that at times.
Methylene Blue helps your mitochondria, research it.
Lower Fructose, Lower Sodium + Fasting for Autophagy/Mitophagy. Result = Lower Free Radicals, lower Oxidative Stress, lower Uric Acid. Thanks Dr PerlMutter, you advice is powerful as usual.
What is best fasting regiment ? Thanks...
My takeaway is; 1. We have evolved to fatten up in the fall and hibernate through the winter. 2. The deeper we dig into things, the more questions we come up with.
Something else people forget is that the foods that grows locally is enough to sustain and create health. Otherwise we wouldn't be here. You don't need avocados if they don't grow where you are. Find another source of good fat. The further north you go the more you need to choose meat.
Not sure that applies universally. Maybe for people that live in cold climates... People who live in the subtropics and to the equator can be outside year round working, exercising, etc... I think cold weather people get lazy in the fall and realize they need to look good for the beach or pool in the early spring. It's psychological for the cold weather folks
Mitochondria is the powerhouse of the cell…
it's not a mitochondria video until it uses that phrase!
*powerstation
Mitochondria are a microscopic life form that resides within all living cells. And we are symbionts with them. Life forms living together for mutual advantage. Without the mitochondria, life could not exist and we would have no knowledge of the Force. They continually speak to us telling us the will of the Force.
The mighty mitochondria 😁
This study is incredibly interesting re fructose but I can’t see it tells us anything about sodium. The comparison was low sodium vs low sodium with high fructose. Unless you also compare with medium and/or high sodium combined with low or high fructose only the data on fructose is meaningful.
That was to be my comment exactly. Thank you!
Yes, that seems glaringly obvious. Surely there's an explanation (by the researchers) regarding this point. I can't imagine what it would be though. Then again, there's a PLETHORA of poorly designed "bunk" research/studies in publication. I wonder what Peter Attia's, author or co author of a publication of some sort called "studying studies", opinion would be should he take an in depth look at it?
Sodium is an enzyme inhibitor.
@@bryantcofty2709 At this point, I’m cynical enough to think it had to do with funding based on the “low salt = good” message.
We are electric. Need sea salt, Need real salt.
You are a true life saver Dr. Pearlmutter. I am always blown away by your depth of knowledge and how simply you explain it to us. May you be blessed in all things good.
Great presentation, Dr.Perlmutter! Please present more factors/studies how to improve mitochondrial function-
would be highly appreciated.
Red light therapy, sauna exposure around 180 degrees Fahrenheit, regular exercise, and doing cold therapy like ice baths a few times a week. Low sodium diet goes against most Dr's these days
@@cain6981 Add Vitamin D3, the main catalyst in cell energy production
Excellent and interesting presentation! Thanks for the many ways you help all of us learn. You're a great teacher. 🙏
Thank you very much doctor.🙏 This is the clearest and most useful clip on "polyol pathway" mechanism. Such understanding provides for important direction for elimination diets. It was my good health fortune to have listened in.
Thank you Dr. Perlmutter. At my age 80 this. Helps to better understand why my mitochondrial function isn't balanced enough to create new muscle. And healthier skin
Etc. I'll just keep up with my biodynamic agriculture foods and clean diet.
Most nutrition for mitochondria is NIR .near infrared from sunlight especially morning and evening when the uv index is low ,below 3
hi! there, I am wondering if you care to provide a reliable source for your statement? thx.
Can you explain please.
Doing just that. It’s helping.
To several who noted, yes there have been follow-ups showing NaCl is the bigger player in this. Just remember if you cut out or cut way back on Iodized Salt, you must supplement with Iodine....
Central nervous system neurons have a lot more than 1,000 mitochondria! The range is between 2,000 and 2,500. Cardiomyocytes also contain about that same number. Highly physiologically active cells found in the kidneys, liver and spleen generally number over 1,000 mitochondria.
Although it's been a while, the director of the mitochondrial lab I worked in said that the current (2010) estimate of mitochondria in the ovum is 250,000. However there was speculation that the number may be as high as 1 million.
Note that mitochondria compose 10% of human body weight. The number of mitochondria in the human body is roughly 10^17.
Great info, thanks..
. sep.t3- no brnach*
Wow, thats a neat fact.
David Perlmutter should win a Nobel Prize. Incredible video.
Wow! I heard that salt could cause oxidative stress but didn't understand why and it gives the answer, thanks for it.
High salt and fructose intake are a marker for a diet high in processed food. However seems to me that fructose is the driver not the salt. See Richard Johnsons' research on fructose.
High salt does the same as fructose, also glutamine in diet. But ofc too low salt is very bad or worse. Salt is also a driver for sure also creates uric acid reaction.
But some salt before exercise is very healthy for heart providing more blood volume and so less need for oxygen for heart in hard situation or while digesting and moving with high blood requirement.
Thank you Doctor Perlmutter. Excellent presentation.
Please continue with U tubes. I'm a naturopathic person with HSV and I research mitochondrial support and thymus regeneration. I will watch mito u tubes more than once as I am getting very familiar with specific medical terms. Appreciate you Bonnie
Didn't know there was a test for Mitochondrial density, appreciate the info.
Agree. How or what do you order on a regular lab requisition?
Hello , right ?
the company viome tests mitochondria also
They will test you anything, if you pay enough. They will also make you believe it is important.
Thank you Doctor! Liked and Subscribed. Just started reading your Grain Brain book... fascinating! Keep up the great work!
I love these theories about early man that are pure speculation, but are used to explain current medical theories.
It's like being a weatherman.
Good analogy. Imagine being without the weatherman.
@@michaelb41 Knowing what the weather is predicted to be has never changed what I do in any particular day. Sure, some people live under threat of tornados and hurricanes, but that is what the public safety system is for.
Likewise, these theories have zero impact on how most people liver their lives.
I can do without them both.
❤😂
I am retired, and I don't buy very many new books now-a-days !, But I bought 'Drop Acid" yesterday ! (It cost $ 31.76 ) Thanks for your sincere efforts to help us all !
try your library...they have great stuff
Many thanks for the information.
From another video I was told that the intake of sodium (preferably in the form of sea salt or Himalayan salt, as these are rich in many other minerals) should be counterbalanced by the right amount of potassium (leafy salad, avocados, bananas etc.) and that half a teaspoon per day, especially when transpiration is increased, is a good thing to add.
you need potassium and magnesium regardless of how much sodium you consume. Its just best those 3 to be in synergy for optimal cell energy, hydration and ofc your blood pressure. BTW - potatoes are one of the best potassium sources. They can feed you, be tasty as heck and are low calories if you are looking for that hehe. Carrots also have plenty of potassium. And fresh carrot juice is just heaven.
But is potassium chloride in anyway heat sensitive/damaged?
Animal products contain potassium.
@@danielmason8574 No.
@@veniqer They do, but the most potassium-rich food sources are fruits and vegetables.
💖 Thank you for a very helpful and informative video..your delivery of info is really great...
I'm confused. It seems that many respected doctors & researchers have - in recent times - indicated that salt is of no concern because the body knows how to deal with excess salt/sodium.
Latest research that I have seen is that people are more likely to have issues with low sodium than high. Salt intake is not an issue if you have good kidney function.
Would have been nice to see another category that were fed just low fructose
@@michaeltrumper high salt intake works exactly the same way as fructose or rather causes uric acid production check out Richard Johnson talking about it deeply
High salt has effects. Body knows how to deal with toxins too should you take toxins? Salt also makes hungry.
@@szymonbaranowski8184 True, but in context, it is much bigger risk of people having too low salt intake than loo low fructose. Or to put it another way, there is a requirement for endogenous salt, but none for fructose.
So, low sodium = no significant change. Low sodium/ low fructose = significant positive change. Why didn't the study include the effect of low fructose in isolation? Also, am curious on the effects this would have on subjects not overweight-- of normal healthy weight?
High sodium is the same as fructose. Literally spikes uric acid the same way
Yes but combining things can be significantly different than how things work by themselves.
So really both should be studied by them selves in order to get a more clear picture.
Salt is highly necessary for many of the functions of the body and you can just cut it out without there being problems.
I agree would love to have seen the low fructose numbers by themselves
Doctor, in the study they isolated low sodium but not low fructose separately, this is incomplete, I would be interested in a further study.
Would you PLEASE post the link to this study in the lowbar? Thanks!
why did the study fail to look at just Fructose w/o a change in Salt ? did they cherry-pick it out?
I kept walking past your book until late last month. Gout hit my ankle again. Coincidentally our health group, we had others gout confirmed by labs. Found your UA-cam’s
Now our group of 300 owns 30meters and wow… 75% (roughly) have levels over 7.
Ordered bulk Quercetin Glycine and Potassium Citrate to start.
I read your book, "Drop Acid," and I'm skeptical of subclinical hyperuricemia in the absence of excessive carbohydrates. Are you sure the "independent" risk factors of UA are really independent at the subclinical level? I suspect there are cofactors that are not accounted for, as carnivores would all be suffering the consequences, and there have been plenty over the ages. I think fructose (or excessive other carbohydrates), for example-even in high fiber foods-is a likely cofactor, for sodium too. I'm sensing a potential plant-based bias and/or dependence on low-quality epidemiological studies.
PS: My suspicion is that people who strictly control carbohydrates may not need to worry about subclinical hyperuricemia, and that in that context, sodium is also not an issue. I can't prove it, but I'd like you to tell me if you know why that's wrong-because we're both after the truth.
You will definitely have high uric acid levels if you eat only meat, but that does not really mean anything in and of itself. It's not the uric acid itself causing issues, though it seems that way. It is your liver (not kidneys) being metabolically deranged that makes your kidneys unable to deacidify the blood enough to keep uric acid crystals from forming. Make sense? Probably not, but it is not a simple subject.
@@LTPottenger thoughtful, thanks........let's hope the doc here deals with the subject of upper gi tract glycan binding lectins and their relationship with acidic food consumption......
Great presentation!
Excellent video. Thank you
Lovely info. Can you please mention the test name for mitochondrial density. Thanks.
Thank You! Always interesting and informative.
What the Swedish news used from this study was the sodium angle...and how much salt there is in processed meals...
Knowing what you just said certainly makes this study more understandable. Processed salt in processed foods! Natural salt has 2% trace minerals which is extracted in commercial salt. When harvested from the sea, salt contains 14% moisture.
Also, sea salt has not been crushed by heavy machinery, thus causing very sharp splinters of crystal which can irritate the endothelia of blood vessels and capillaries, thus causing systemic inflammation.
very informative ... well presented
Letting sodium and fructose relative to what? What was the baseline level for the folks who experienced the decreases?
Fascinating.
Thank you
So mitochondria dna has increase after 8 weeks of low sodium and fructose diet. Did this translate to the participants feeling to have more energy or had any measured weight loss? Just an increase in mitochondrial dna on it's own doesn't appear to be a useful effect otherwise?
Agape 💙 .Dr. David. Ty 4 telling me the truth. I'm on it.
Hi doc, great presentation. What blood test reveals the mitochondrial count in the white blood cell?
I second this question, what is it ?
@DavidPerlmutterMD Would you consider doing a video on how to improve mitochondrial efficiency as well ? Thank you for the amazing content that you create to educate us. Much appreciated ! :)
Get morning sunlight on your retina and skin for improved mitochondrial health, and avoid blue light after sunset.
from my undergraduate studies in kinesiology i can tell you that inside the walls of the mitochondria a cascade of numerous chemical reactions takes place to produce the energy molecule atp (adenosine triphosphate). something like 75% of these reactions involve magnesium, so i make sure my magnesium content is topped up.
@@TerriblePerfectionwell said
This was powerful info
Thanks a lot for the advice
Did they not control for only low-fructose? I saw only the comparison between low-sodium and low-sodium, low-fructose.
I would have found additional interest in seeing the results of a group that was only low fructose.
The study was from 2013, have there been follow ups to confirm the finding? Also why not have seperate studies on fructose and salt? is there a synergy between them?
To several who noted, yes there have been follow-ups showing NaCl is the bigger player in this. Just remember if you cut out or cut way back on Iodized Salt, you must supplement with Iodine....
@@BluesDoctorIF your thyroid wirks
Interested if instead of lowering sodium you raised potassium and magnesium
Very interesting but what about for those that are not obese? I thought we need salt if we work out a lot, do fasting etc... I do keto ore mostly so sugar intake is very l low.
QUESTION: How do we know which is the cart and which is the horse? Do people with low mitochondrial function feel energy-starved and need to eat carbs for energy, so that's how they gain weight? Rather than mitochondrial function declining as a result of weight gain?
Why do scientists so often mix multiple variables into studies? Did I miss something? Where is the study of low sodium on mitochondria and low fructose on mitochondria? What sense does it make to introduce another variable? Apparently sodium had minimal effect, but fructose was a significant difference.
That's the honest truth. The only thing that likely has any effect is sugar. Salt is negligent.
great info.
I've read some studies by Rick Johnson. The polyol reaction seems to be key to uric acid levels which in turn prompts conversion of glucose to fructose (and triggering the 'uricase mutation'). His take on it (interview with Dr. Peter Attia) is that it's relative sodium levels - so dehydration can do this as well. His take on it was (paraphrasing) "if you're going to eat something salty, drink liquids first).
It's an interesting area. I hadn't made the connection with mitogenesis and mitophagy but how else would an organism reduce energy consumption? Subscribed, BTW.
Do we know what happened to the energy levels, the blood pressure or cognitive function of the study subjects?
Sodium causes leptin resistance, thus making people hungry. Fructose causes insulin resistance of the liver, thus making toxin processing more difficult. Combinations might synergize to increase advanced glycation end products and inflammatory processes that induce mitochondrial apoptosis in white blood cells?
Question: I see people including children on you tube videos recording extreme carnival rides like on a slingshot or Rollercoaster and often times they scream and even pass out...just wonder what is the impact on the brain..could they be doing irreparable damage?
You mention a simple blood draw test to measure mitrocondira in the white blood cells. What is the name of this test? Thank you
But wait, 6 grams of salt/sodium is NOT a low sodium diet.
salt is an enzyme inhibitor, so it can't be that great. need All my enzymes.
Definitely NOT what I thought when I saw “drop acid”. This is really cool though.
So, how does one go on a low sodium (salt) diet and not threaten the essential level of hydrochloric acid in the stomach? I would suggest using chloride forms of minerals such as magnesium chloride, calcium chloride, zinc Cl, etc where ever possible.
What’s the source of sodium they removed? Table salt? I imagine everything in moderation even applies to things like Redmond’s Real Salt. But specifically calling out the source could help determine if iodized table salt is causing oxidative stress.
If I read it correctly at 5:20, low sodium was defined as less than 6,000 mg, which is still a lot
How long should it take to drop Uric Acid, say, to 6, from 7, if following the protocol described in your book?
Thanks for providing the interesting finding. However, what could be the potential links between mitochondria and fructose/salts? It seems to me that conducting a study based on already obese individuals don’t make a lot of sense since they need to reduce daily nutrients intake anyway.
If you do a little digging on pubmed you'll find this study was called into question with the sample size too small and the variance of results too large to draw any meaningful conclusions.
In addition to many other supplements, I am taking 20 mg per day of pyrroloquinoline quinone or PQQ. Are there good substantive studies done on this compound with respect to mitochondrial function and mitochondrial genesis?
Pqq works but use it in conjuction with exercise or just walking do ur daily steps
This seems to me another good reason to cut off fructose. Just wonder why it toke 8 weeks before we see big changes in mitochondria.
If my blood test shows low sodium is that the same as reaffirming a low sodium diet? Sodium is a necessary mineral for electrolytes assisting in the electrical aspect of exercise and the heart.
What happens to the mitochondria if the person has a neutropenic fever due to chemotherapy? I had breast cancer and after my first dose of chemo, I got neutrpenic fever after my first dose of chemo. I was told that my neutrophils were 0.5 and normal was 13. I recovered, but I was wondering if that is why I had 'brain fog' afterwords the chemotherapy and radiation. That was 10 years ago. I am currently eating a low sodium and most of all, low sugar (carb) diet. I got off of sugar using monk fruit and now I am trying to eat less real fruit with the exception of a few, like kiwis. I am also taking vitamins such as MNM and trans reseratrol. I am noticing that my I have been retaining information better and memory has improved. Please tell me what you think about this.
Dr. Peter Attia address many health issues that you would be interested in. First in my mind is becoming bullet proof to illnesses. Largely that is due to exercise. Attia has many videos on UA-cam and podcast. Best wishes in your journey to wellness and greater health.
I'm wondering just how well the white blood cell mitochondrial density correlates-serves as a proxy for muscle tissues (?). Seeing a 70-fold increase in mitochondrial density sounds like it would mean a fantastic rise in potential muscle cell performance. I know there would still be other muscle performance limiting factors, but at least mitochondrial density should no longer be one.
Now we need to know what foods not to eat that are high in fructose
DOING INTERMITTENT FASTING, THE LAST THING ONE WANTS IS LOW SODIUM AS YOU EXCRETE MORE SODIUM WHILE FASTING.
Bullshit. You pee pure water from fat. body saves all minerals while fasting. I hope you don't go hard exercise while fasting lol
High sodium gets you fat in caloric deficit.
@@szymonbaranowski8184 This is bullshit. I've watched numerous vids from people who are experts on fasting & what I said is fact!
Drink coconut water, and lemon water with salt to keep sodium levels up.
Fact? only in your mind. I've watched numerous vids & read books on the subject too!
Maybe there's another explanation! Less fructose means a lower energy in the circulating nutrients and thus a compensation to get the work done with lower energy nutrition is a greater number of mitochondria.
You are spot on. And anaerobic training can quadruple muscle mitochondrial count.
I doubt that. Mitochondria must have oxygen to produce energy...
While mitochondria need oxygen to function, is it possible that more mitochondria are produced in an anaerobic environment because of the need for more energy?
Both aerobic and anaerobic training good for mitochondria, zone2 training is increasing “the number of mitoc.” while high intenty like zone3-4 making mitochondria larger in size.
The problem with zone3-4 eventually makes you tired because of that reason zone2 training is much more effective, easy, lowering your hbr but it takes time at least 4 weeks and 3 training for each week. Zone3-4 training you will get results immeadiately,maybe one every 2-3 weeks 1 or 2 speed or interval workout keep you safe.
Sodium reduces production of ATP (interferes with the work of the mitochondria) for 3 hours (it takes the body 3 hours to get rid of excess sodium). So if you eat every 3 hours you are basically toast.
Great comment. Good news for me is this- I eat once a day! Thanks 🎉
I wish they would have added one more arm to this study, low fructose only.
HIIT has been a clear and simple path to increasing my own mitochondria. This stress forces your mitochondria to multiply. Curious if there is any research data on combing both? I have always taken Fish and Flaxseed oil to keep my blood pressure low and scoop up free radicals etc. I am often thought to be 20 years younger then my actual age.
Information, great. Skin, glowing. Jawline, sharp.
Can you do a deep dive on inhalation of Hydrogen Gas relative to its ability to stop free radical damage and protect Mitochondria..?
I had no idea that Willem Dafoe knew so much about mitochondria. 😜
Very interesting. Now, how are we supposed to apply that information? Are we to weigh out sodium in our cooking and consult a table for the amount of fructose in our fruit? (never mind soft drinks, for those who consume them). Let's make it practical, shall we?
that is a different topic. Let's be respectful with content creators, shall we?
Excellent presentation. More than enough to get started, if you're willing to make the effort. Here's a jump start:
"Low sodium" diets are typically 2 grams or less/day. (1 tsp of table salt = 2300 mg of sodium.) For fructose: You can easily find charts online listing "fructose content" for various food. Print it out to keep handy as you "cut down" consumption from where you are now. (Was that really so difficult?)
@@enkidu001 It may be a different topic -- but should it be?
"Was that so difficult?"
Actually, yes. It's not how people cook or eat -- or should cook or eat. It's out of the flow. It's not "handy". People do not -- and should not have to -- interrupt the process to weigh ingredients or to consult a table -- unless they are in commercial production; that's a completely different mindset. Such is my opinion, such as it is.
Ever watch Julia Child cook?
@@Lawrence9Gold One medium banana is about 6 grams of fructose. Mango is the highest in fructose.--1/2 cup and you've about finished your daily allowance. Really...just limit yourself to garnishes and recite to yourself: "This is too good to eat.", and you'll be fine.
Is salt such a problem. Could you do a book on salt?
I'd like to see the same test with a low carb group without combining salt into the evaluation.
I wonder if the advice on sodium would be different if one is fasting and/or on a low carb diet?
I believe uric acid goes up during a fast.
Fasting appears to me to be the key.
It promotes Autophagy and Mitophaggy, as well as Mitochondrial biogenesis. As well as other forms of regeneration in the body, and Neurogenesis.
It reduces oxidative stress, glucose, insulin, and it seems to improve oxygen saturation in the blood.
When my wife has been fasting, her O2 Sat is often 100%, which I find interesting.
I'm the 'Control'! and mine is usually about 95 when lying down.
It's rather like having a 'hand with all the Aces' !! And the 'Goal' is to achieve a Glucose Ketone index of 1 for maximum benefit.
But be Careful...!!
Depends - do you like feeling good or not lol. But for real - if you dont supplement with salt and other electrolytes during fast /low carb diet - chances are - you will feel like shi1. Low blood pressure, irritable, low energy, all that jazz.
What was the sample size, did they placebo-control the overweight subjects and were the overweight participants dieting?
Thank you for your work on uric acid. In hopes that you will also study the effects of bovine growth hormones in our meat, and the who knows what they are injecting chickens and pigs with, but whatever it is, it's affecting our health in a very bad way. Almost as if they intended to wipe us out... :(
what kind of diet is low sodium and low fructose?
You didn't mention potassium values !!!
It is thought-provoking for me. Please advise.
- Uric acid is at 7.9.
- LDL is high.
- I am 50 years old.
- I am very active in sports. I cycled 1100 km last month.
- I have no symptoms of high LDL or uric acid.
- I have been struggling to lose 5 kg of weight for the past year.
- I haven't used added sugar for 6 months.
- I eat mostly boiled vegetables with olive oil once a day.
- I occasionally eat a small amount of fruit (fructose).
- I usually don't add salt to my food.
Please advise on what I should do to lower my uric acid levels, as I can feel that I am not metabolically healthy anymore. My physician is not very helpful.
Thank you
thank you
This study, or at least the way he explained it, seems to have convolved fructose and sodium impact. It should have studied them independently as well as together. That said, we're not ingesting more sodium than people years ago who didn't have these health issues. While there was a surge in HFCS in processed foods, that alone doesn't account for the explosion of chronic health issues that the public is experiencing across the board.
This feels like yet another hammer trying to find a nail.
More on point research is now showing that glyphosate (Roundup) is responsible for mitochondrial damage, gut flora damage, and damage to cellular protein synthesis and dismantling. Its use in big agriculture - starting in the 90s - lines up with the increase in these diseases. And there is evidence that the company that created Roundup has known about these issues for some time. But, while other countries haven't allowed or are outlawing this toxic chemical, the US government and agriculture industry have been resistant to change.
The medical system is looking at everything but the elephant in the room. My conclusion is that it seems to have been compromised by both big pharma and big agriculture which share common ownership.
Those of us who are damaged by years of glyphosate ingestion have to reduce our sodium and carbohydrate intake to compensate for the damage this chemical has done to our bodies. But, reducing sodium and carbohydrates won't fix the root cause of the problem. Until it is addressed, eat organic food and avoid processed food. And demand that the elephant be seen.
A link to relevant studies would help.
" Low fructose and low salt diets increase mitochondrial DNA in white blood cells of overweight subjects"
R Hernández-Ríos et al. Exp Clin Endocrinol Diabetes. 2013 Oct
Some very basic digging on pubmed finds this study was called into question with the sample size too small and the variance of results too large to draw any meaningful conclusions.
I experimented with my own body and salt mixtures and now make and use a mix of 25% KCl and 75% Himalayan salt , all group up and mixed well.
What does it do?
Where do you get Potassium chloride?
Seems interesting to me. Cold and heat shocking affect mitochondrial body function. Cold propagates them and heat attenuates them but this paper they seem to indicate low oxidative stress also propagates them. So 2 types of stress and 1 lack of stress improves functionality? Could this latter part because Mitochondria are proto-bacteria and potentially reproduce is a similar fashion? The DNHP and uric acid decrease seems like a benefit regardless.
So Dr. Pearlmutter: What do I do if I’m on keto and are diabetic with past history of high ( not now) cholesterol and I’ve been told I have to take more sodium due to my keto diet & greater rates of losing that & other electrolytes but I’m 68 female with Alzheimer’s big in my family so I want mitophagy & greater mitochondrial coupling. How much sodium is the right amount for me to have daily? I’m confused.
@@aliciastanley5582 want to have aswers these questions too..
High uric acid levels caused by excessive umami foods. Glutamate in red meat, organic meat, others triggers uric acid. Stan Ekberg discusses this
You forgot about salt
Being on a ketogenic diet gives me mighty chondria.
My mitochondria are doing good thanks but I am worried about my cytosomes and my Golgi apparatus. People are just not taking care of these organelles and there is so little information available could you please help?
In the study, did they use fructose in the form of fruits?
Would the antioxidants in the fruits reduce the negative effects?
On a mostly Vegan diet consisting of potatoes, fruits, veggies and no added salt,
my results are: Uric Acid 5.0, HbA1c 4.7% (avg 3 mo BG 86), Chol 185, TG 78.
I have gone totally off all sugars including fructose since April 2023 . SOmehow though my A1C has come down drastically, for the first time I found that my uric acid levels are elevated to 6.7 . Im completely confused as to what to do what to have how to control this . Could you please advise
Mindblowing
If you do a little digging on pubmed you'll find this study was called into question with the sample size too small and the variance of results too large to draw any meaningful conclusions.
The study is called "Low fructose and low salt diets increase mitochondrial DNA in white blood cells of overweight subjects"
R Hernández-Ríos et al. Exp Clin Endocrinol Diabetes. 2013 Oct